Bpic006307.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus picipes
Gene Symbol
zfp-2
Assembly
GCA_014737485.1
Location
JACXIP010000013.1:3706189-3711224[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 1.3e-06 0.00013 22.4 2.5 1 23 85 108 85 108 0.95
2 12 4.1e-06 0.00042 20.8 4.8 2 23 115 137 114 137 0.95
3 12 0.0043 0.43 11.3 3.4 1 21 143 163 143 168 0.94
4 12 3.7e-08 3.7e-06 27.3 1.7 1 23 175 197 175 197 0.99
5 12 0.00015 0.015 15.9 0.4 2 23 207 228 206 228 0.96
6 12 0.00025 0.025 15.2 0.4 2 23 235 256 234 256 0.97
7 12 1.4e-06 0.00014 22.3 2.1 1 23 262 284 262 284 0.99
8 12 1.8e-05 0.0018 18.8 2.5 1 23 290 312 290 312 0.95
9 12 6.6e-06 0.00067 20.2 0.8 1 23 318 341 318 341 0.94
10 12 2.4e-05 0.0024 18.4 0.3 1 23 347 369 347 369 0.95
11 12 1.9e-08 1.9e-06 28.2 1.7 1 23 375 397 375 397 0.99
12 12 3.6e-05 0.0036 17.9 1.6 2 23 404 426 403 426 0.94

Sequence Information

Coding Sequence
ATGGAAGAAATAATGGACATATGTAGAGAAGAAGATGATTCCAACATTTTGCAGTTAAGGAGTCTTGAGAATTATGAATCAGATGATGAAGAGAAAGATAATAATCCAGACTATATTAATAATTCCAATATGGAAGATGACAGTTCCAATAATCAAAAAAATTATAATGATAAGCCAATAATTATACCTGTACCTGATACACAATGTCATTGCTGTGCTGAAGATTTAAGCACTGCGCACAGTGGTGGTGAATTTAAATGTCAACACTGTAACCTATCATTTAAAAAGAAATCATCCTTAGAAAGACACATTGTGGTAATTCATTGGCAGTGTGATTCATGTACCTGCAAAGATTGTGGAGAATCATTTCGTGATAAGAAGTCACTAAACAAACATCGTTATACTACTCATGCTGATAAAAAAATTTTCAGATGTGAGCCTTGCGATACTTATTTTTCACGAATGTATCATTTAAATCGCCATATAATGCAATCTGGATGTCATGGAAATATTCTTAATACATATAGTTGTCAAGTTTGCCAAAAGATTTTCACGCGGAAGGATAATTTACGTGAACATTTACGAACTCACGCCGGAACTCCTCAAAGACAAAAGAAACCTTGTAGATATTGTCCTAAGGAATTTTTTACTAACCAACAATTGTTAATTCACGAACGTGTACACACAGGAGAACGACCAGTTCAATGCGATTTATGCCCAAAGTCTTTTCTATCTTCTCTTGCATTAAAGAAACATAGACGTGTACATACAGGAGAAAAACCATTTGAATGCCAATATTGTCAAAAAAAGTTTGCTGCTCGGGAAACTTTAAATCGTCACCAAAGAACTCATACTGGCGAAAAACCTCATGTTTGTCAATATTGCTCTAAATCATTTATTCAGGCTGCTCAATTGAGAGCACATATATTTCATCACACTGGTGAAAATGGTTTTTACTGTGAGGTATGTGGGAAAGCATTTAGTAGAAAAGCTCGGTTAAATGTTCACAAAAAATTTGTTCATGAAGGAGCCACCCCATTTGCATGTCAAATGTGTGAAAAGAAATTTATAAGAAAAGAAGATCTGGTTAAACATGTAATACTTCATACAGGAGTTAAAGCATATAAATGTGATAAATGTACAAAAGCTTTTTCTACAAAATCTTCCTTACAAGCTCATTTAAATACTCATAGACGAGAACCACCACAATCTTGTGTTGAATGTAATAGAGTTTTCATACGTCAAGATTGTTTAATGAGGCACATTAAAGCAAAACACCGTGATCTATTAGAAGAAAATTTACAAATACAATTATATAATATTGCAACAGTTGCTGCAGAGAAAACAAAGAAAGGAGAGTCTACTCAATTTTCCACTGAAGAATTGTTAAAAGCCATAGCTGATCTTTTGAAAATATTAATTGATGATGATACTCTTCAGCTCTTTGGTTGGCCTGATGCCCCTATTGAAGATATTGTACAAGCTGTAATTAGACGATGTGGGCATGAACCATTAACATCAGAATGTAGATTACCTTTTGATGAAAGATTAAGGGAAAACATAAAGTGTTTATTTATGGTTGTTATAGAAGATAATATGGTAAAATCTCTTTTAACAAGAAAGACAATAGATGACGTAATTGTACATATTTTGAAACTTTCAAAGGAAGCAAATTTATAG
Protein Sequence
MEEIMDICREEDDSNILQLRSLENYESDDEEKDNNPDYINNSNMEDDSSNNQKNYNDKPIIIPVPDTQCHCCAEDLSTAHSGGEFKCQHCNLSFKKKSSLERHIVVIHWQCDSCTCKDCGESFRDKKSLNKHRYTTHADKKIFRCEPCDTYFSRMYHLNRHIMQSGCHGNILNTYSCQVCQKIFTRKDNLREHLRTHAGTPQRQKKPCRYCPKEFFTNQQLLIHERVHTGERPVQCDLCPKSFLSSLALKKHRRVHTGEKPFECQYCQKKFAARETLNRHQRTHTGEKPHVCQYCSKSFIQAAQLRAHIFHHTGENGFYCEVCGKAFSRKARLNVHKKFVHEGATPFACQMCEKKFIRKEDLVKHVILHTGVKAYKCDKCTKAFSTKSSLQAHLNTHRREPPQSCVECNRVFIRQDCLMRHIKAKHRDLLEENLQIQLYNIATVAAEKTKKGESTQFSTEELLKAIADLLKILIDDDTLQLFGWPDAPIEDIVQAVIRRCGHEPLTSECRLPFDERLRENIKCLFMVVIEDNMVKSLLTRKTIDDVIVHILKLSKEANL