Basic Information

Insect: Frieseomelitta varia
Gene Symbol: zfp-2
Assembly: GCA_011392965.1
Location: WNWW01000168.1:369552-372346[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0009 0.056 13.2 0.2 1 20 27 46 27 48 0.95

2 13 1.2e-06 7.3e-05 22.2 2.5 1 23 126 149 126 149 0.95

3 13 3.9e-06 0.00024 20.6 4.5 2 23 156 178 155 178 0.95

4 13 0.0039 0.24 11.2 3.4 1 21 184 204 184 209 0.94

5 13 3.9e-08 2.4e-06 26.9 2.2 1 23 216 238 216 238 0.98

6 13 3.8e-05 0.0023 17.5 0.5 2 23 248 269 247 269 0.97

7 13 0.00022 0.014 15.1 0.4 2 23 276 297 275 297 0.97

8 13 0.00027 0.017 14.8 2.4 1 23 303 329 303 329 0.93

9 13 1.6e-05 0.001 18.7 2.5 1 23 335 357 335 357 0.95

10 13 6e-06 0.00037 20.0 0.8 1 23 363 386 363 386 0.94

11 13 1.6e-05 0.001 18.6 0.2 1 21 392 412 392 413 0.94

12 13 1.7e-08 1.1e-06 28.0 1.7 1 23 431 453 431 453 0.99

13 13 3.2e-05 0.002 17.7 1.6 2 23 460 482 459 482 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0009	0.056	13.2	0.2	1	20	27	46	27	48	0.95
2	13	1.2e-06	7.3e-05	22.2	2.5	1	23	126	149	126	149	0.95
3	13	3.9e-06	0.00024	20.6	4.5	2	23	156	178	155	178	0.95
4	13	0.0039	0.24	11.2	3.4	1	21	184	204	184	209	0.94
5	13	3.9e-08	2.4e-06	26.9	2.2	1	23	216	238	216	238	0.98
6	13	3.8e-05	0.0023	17.5	0.5	2	23	248	269	247	269	0.97
7	13	0.00022	0.014	15.1	0.4	2	23	276	297	275	297	0.97
8	13	0.00027	0.017	14.8	2.4	1	23	303	329	303	329	0.93
9	13	1.6e-05	0.001	18.7	2.5	1	23	335	357	335	357	0.95
10	13	6e-06	0.00037	20.0	0.8	1	23	363	386	363	386	0.94
11	13	1.6e-05	0.001	18.6	0.2	1	21	392	412	392	413	0.94
12	13	1.7e-08	1.1e-06	28.0	1.7	1	23	431	453	431	453	0.99
13	13	3.2e-05	0.002	17.7	1.6	2	23	460	482	459	482	0.94

Sequence Information

Coding Sequence: atgTCTGCTGAACAAGAAGAATCTACCGACGCAGAAGTTATTGCTCATGATGgtcaaattatacaaattataacagATTATGAATGTGTTACTTGCCATCGTATCTTTCAGTCGCAAGATATGTTGAAGGAACATTTAGATATATGCAGAGAGGAAGATGACAGTAGCATATTGCAATTAAGACTTGAGAATTATGAATCAGAAGATGAAGAGGAGAAAGATAATAGCTCAGATTgtgttaataattctaatgCAGAAGATGACAGTTCCAATAataagaagaataataatgataagcCAGTGATTACGCCTGTACCTGATACGCAATGTCATTGCTGCGCCGAGGATTTGACCACTGCACATAGTGGTGGGGAATTTAAATGTCAGCATTGTAAtctatcgtttaaaaaaaagtcgtcTTTGGAAAGACACATTGTGGTAATTCATTGGCAGTGTGATTCGTGTACCTGTAAAGATTGTGGAGAATCATTTCGTGATAGAAAATCATTGAATAGACATCGTTATACAACTCACGCtgataagaaaattttcagatGCGAGCCCTGTGATACCTATTTTTCGCGGATGTATCATTTAAATCGTCACATAATGCAGTCAGGATGTCAcggaaatattcttaatacGTATAATTGTCAAgttTGCCAGAAAATGTTTACACGTAAAGATAATCTACGTGAACATCTACGAACACATGCTGGAACTCCTCAGAGACAGAAGAAGCCTTGTAAATATTGTCCTAAAGAATTCTTTACTAATCAACAATTGTTAATTCACGAACGTGTACACACAGGAGAACGACCAGTTCAGTGCGATTTATGCCCAAAATCTTTTCTATCTTCTCTTGCATTAAAAAAACACAGACGTGTACATACAGGAGAAAAACCATTTGAATGTCAATATtataaatatacttGTCAAAAGAAGTTTGCTGCTCGGGAAACTTTAAATCGTCATCAGAGAACTCACACCGGCGAGAAACCTCACGTTTGTCAATATTGttcaaaatcatttattcAGGCCGCTCAATTGAGAGCACATATATTTCATCATACTGGTGAAAATGGATTTTATTGCGAAGTATGTGGAAAAGCATTTAGTAGAAAAGCTCGGTTGaatgttcataaaaaatttgttcacgAAGGAGCAACACCATTTACGTGTCAAAtgtgtgaaaagaaattcataagAAAAGAAGATCTTGTTAAGCATttaattgtagtagattttaatataatgttagtAAACTGTAGTATTGTCTTTGTTGCAGCTTATAAATGTGATAAATGTACGAAagcattttctacaaaatcttCTTTGCAAGCTCATTTAAATACTCATAGACGAGAGCCACCACAATCTTGCGTCGAATGTAATAGGGTCTTCATACGCCAGGATTGTTTAATGAGGCATATTAAAGCAAAGCATCGTGCTCTGCTAGAAGAAGTGATGGACGAagtcgaaaaaaagaatttgcaaacgcaattatataatatcgcCACAGTTGCTGCAGAAAGAACAAAGAATGGAGAGTCTACAAAATTGTCCACTAAGGAATTGCTAGAAGCTATCACCGaccttttgaaaatattaattgatgaCGATACTCTTCAGCTTTTTGGTTGGCCTGATGCTCCTATTGAAGATATCGTAGAAGCTGTAATTAGAAGGTGTGGACACGAACCGTTAACATCAGATTGTAAATTATCCTCTGATGAAAGATTAagggaaaatataaaatgcttGTTTATGGTTGTCATAGAAGATAATAGGGTAAAATCTCTTTTAACAAGAAACACGATAGACGATGTTATTGTACAtgttttaaaactttcaaaagaaacaaatttatag
Protein Sequence: MSAEQEESTDAEVIAHDGQIIQIITDYECVTCHRIFQSQDMLKEHLDICREEDDSSILQLRLENYESEDEEEKDNSSDCVNNSNAEDDSSNNKKNNNDKPVITPVPDTQCHCCAEDLTTAHSGGEFKCQHCNLSFKKKSSLERHIVVIHWQCDSCTCKDCGESFRDRKSLNRHRYTTHADKKIFRCEPCDTYFSRMYHLNRHIMQSGCHGNILNTYNCQVCQKMFTRKDNLREHLRTHAGTPQRQKKPCKYCPKEFFTNQQLLIHERVHTGERPVQCDLCPKSFLSSLALKKHRRVHTGEKPFECQYYKYTCQKKFAARETLNRHQRTHTGEKPHVCQYCSKSFIQAAQLRAHIFHHTGENGFYCEVCGKAFSRKARLNVHKKFVHEGATPFTCQMCEKKFIRKEDLVKHLIVVDFNIMLVNCSIVFVAAYKCDKCTKAFSTKSSLQAHLNTHRREPPQSCVECNRVFIRQDCLMRHIKAKHRALLEEVMDEVEKKNLQTQLYNIATVAAERTKNGESTKLSTKELLEAITDLLKILIDDDTLQLFGWPDAPIEDIVEAVIRRCGHEPLTSDCKLSSDERLRENIKCLFMVVIEDNRVKSLLTRNTIDDVIVHVLKLSKETNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00225380;
90% Identity: iTF_01420400;
80% Identity: -