Basic Information

Insect: Bombus cullumanus
Gene Symbol: zfp-2
Assembly: GCA_014737535.1
Location: JACXIX010000093.1:365009-369310[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0011 0.11 13.1 0.2 1 20 62 81 62 83 0.95

2 13 1.5e-06 0.00014 22.2 2.5 1 23 161 184 161 184 0.95

3 13 7.1e-06 0.00067 20.0 5.4 2 23 191 213 190 213 0.95

4 13 0.0048 0.45 11.1 3.4 1 21 219 239 219 244 0.94

5 13 4.2e-08 3.9e-06 27.0 1.7 1 23 251 273 251 273 0.99

6 13 0.00017 0.016 15.7 0.4 2 23 283 304 282 304 0.96

7 13 0.00028 0.026 15.0 0.4 2 23 311 332 310 332 0.97

8 13 1.6e-06 0.00015 22.1 2.1 1 23 338 360 338 360 0.99

9 13 2e-05 0.0019 18.6 2.5 1 23 366 388 366 388 0.95

10 13 7.5e-06 0.0007 20.0 0.8 1 23 394 417 394 417 0.94

11 13 2.7e-05 0.0025 18.2 0.3 1 23 423 445 423 445 0.95

12 13 2.2e-08 2e-06 27.9 1.7 1 23 451 473 451 473 0.99

13 13 4e-05 0.0038 17.7 1.6 2 23 480 502 479 502 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0011	0.11	13.1	0.2	1	20	62	81	62	83	0.95
2	13	1.5e-06	0.00014	22.2	2.5	1	23	161	184	161	184	0.95
3	13	7.1e-06	0.00067	20.0	5.4	2	23	191	213	190	213	0.95
4	13	0.0048	0.45	11.1	3.4	1	21	219	239	219	244	0.94
5	13	4.2e-08	3.9e-06	27.0	1.7	1	23	251	273	251	273	0.99
6	13	0.00017	0.016	15.7	0.4	2	23	283	304	282	304	0.96
7	13	0.00028	0.026	15.0	0.4	2	23	311	332	310	332	0.97
8	13	1.6e-06	0.00015	22.1	2.1	1	23	338	360	338	360	0.99
9	13	2e-05	0.0019	18.6	2.5	1	23	366	388	366	388	0.95
10	13	7.5e-06	0.0007	20.0	0.8	1	23	394	417	394	417	0.94
11	13	2.7e-05	0.0025	18.2	0.3	1	23	423	445	423	445	0.95
12	13	2.2e-08	2e-06	27.9	1.7	1	23	451	473	451	473	0.99
13	13	4e-05	0.0038	17.7	1.6	2	23	480	502	479	502	0.94

Sequence Information

Coding Sequence: ATGGAAGAAATAATGGAAATCGTGAAAGTTGAGGATGCAGTGTTCTTAGAAGATACAGCGCTAGAAAATTTATTCGATCCAGAAAACGTACAAGAAACTATTATAATGTCTGCTGAACAAGGAGACTCCACTGACACAACAGTTATTGCTCATGACGGTCAAATTATACAAATTATAACAGATTATGAATGTGTTACATGTCATCGTATCTTTCAATCACAAGATATGCTAAAGGAACATTTAGACATATGTAGAGAAGAAGATGATTCCAACATTTTGCAGTTAAGGAGTCTCGAGAATTATGAGTCAGATGATGAAGAGAGAGATAATAATCCAGACTATATTAATAATTCCAATATGGAAGATGACAGTTCCAATAATCAAAAAAATTATAATGATAAACCAATAATTATACCTGTACCTGATACACAATGTCATTGCTGTGCTGAAGATTTAAGCACTGCGCACAGTGGTGGTGAATTTAAATGTCAACACTGTAACCTATCATTTAAAAAGAAATCATCCTTAGAAAGACACATTGTGGTAATTCATTGGCAGTGTGATTCATGTACCTGCAAAGATTGTGGACAATCATTTCGTGATAAGAAGTCACTAAACAAACATCGTTATACTACTCATGCTGATAAAAAAATTTTCAGATGTGAGCCTTGCGATACTTATTTTTCACGAATGTATCATTTAAATCGCCATATAATGCAATCTGGATGTCATGGAAATATTCTTAATACATATAGTTGTCAAGTTTGCCAAAAAATTTTCACGCGGAAGGATAATTTACGTGAACATTTACGAACTCACGCCGGAACTCCTCAAAGACAAAAGAAACCTTGTAGATATTGTCCTAAGGAATTTTTTACTAACCAACAATTGTTAATTCACGAACGTGTACACACAGGAGAACGACCAGTTCAATGCGATTTATGCCCAAAGTCTTTTCTATCTTCTCTTGCATTAAAGAAACATAGACGTGTACATACAGGAGAAAAACCATTTGAATGTCAATATTGTCAAAAAAAATTTGCTGCTCGGGAAACTTTAAATCGTCACCAAAGAACTCATACTGGCGAAAAACCTCATGTTTGTCAATATTGCTCTAAATCATTTATTCAGGCTGCTCAATTGAGAGCACATATATTTCATCACACTGGTGAAAATGGTTTTTACTGTGAGGTATGTGGGAAAGCATTTAGTAGAAAAGCTCGGTTAAATGTTCACAAAAAATTTGTTCATGAAGGAGCTACCCCATTTGCATGTCAAATGTGTGAAAAGAAATTTATAAGAAAGGAAGATCTTGTTAAACATGTAATACTTCATACAGGAGTTAAAGCATATAAATGTGATAAATGTACAAAAGCTTTTTCTACAAAATCTTCCTTACAAGCTCATTTAAATACTCATAGACGAGAACCACCACAATCTTGTGTTGAATGTAATAGAGTTTTCATACGTCAAGATTGTTTAATGAGGCACATTAAAGCAAAACACCGTGATCTATTAGAAGAAGTAATGGATGAAGTCGAAAAAAAGAATTTACAAATACAGTTATATAACATTGCAACAGTTGCTGCAGAGAAAACAAAGAAAGGAGAGTCTACTCAATTTTCCACTGAAGAATTGTTAAAAGCCATAGCTGATCTTTTGAAAATATTAATTGATGATGATACTCTTCAGCTCTTTGGTTGGCCTGATGCCCCTATTGAAGATATTGTACAAGCTGTAATTAGACGGTGTGGGCATGAACCATTAACATCAGAATGTAGATTACCTTTTGATGAAAGATTAAGGGAAAACATAAAGTGTTTATTTATGGTTGTTATAGAAGATAATATGGTAAAATCTCTTTTAACAAGAAAGACAATAGATGACGTAATTGTACATATCTTAAAACTTTCAAAGGAAGCAAATTTATAG
Protein Sequence: MEEIMEIVKVEDAVFLEDTALENLFDPENVQETIIMSAEQGDSTDTTVIAHDGQIIQIITDYECVTCHRIFQSQDMLKEHLDICREEDDSNILQLRSLENYESDDEERDNNPDYINNSNMEDDSSNNQKNYNDKPIIIPVPDTQCHCCAEDLSTAHSGGEFKCQHCNLSFKKKSSLERHIVVIHWQCDSCTCKDCGQSFRDKKSLNKHRYTTHADKKIFRCEPCDTYFSRMYHLNRHIMQSGCHGNILNTYSCQVCQKIFTRKDNLREHLRTHAGTPQRQKKPCRYCPKEFFTNQQLLIHERVHTGERPVQCDLCPKSFLSSLALKKHRRVHTGEKPFECQYCQKKFAARETLNRHQRTHTGEKPHVCQYCSKSFIQAAQLRAHIFHHTGENGFYCEVCGKAFSRKARLNVHKKFVHEGATPFACQMCEKKFIRKEDLVKHVILHTGVKAYKCDKCTKAFSTKSSLQAHLNTHRREPPQSCVECNRVFIRQDCLMRHIKAKHRDLLEEVMDEVEKKNLQIQLYNIATVAAEKTKKGESTQFSTEELLKAIADLLKILIDDDTLQLFGWPDAPIEDIVQAVIRRCGHEPLTSECRLPFDERLRENIKCLFMVVIEDNMVKSLLTRKTIDDVIVHILKLSKEANL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00225380;
90% Identity: iTF_00225380;
80% Identity: -