Basic Information

Insect: Bombus pascuorum
Gene Symbol: ZFY
Assembly: GCA_905332965.1
Location: HG995277.1:12126668-12162624[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.7 5e+02 1.8 1.7 2 23 447 467 446 467 0.93

2 13 6.5 6.9e+02 1.4 4.2 1 23 499 523 499 523 0.92

3 13 0.00058 0.062 14.1 0.4 2 22 580 600 579 603 0.90

4 13 0.0041 0.43 11.5 0.6 2 23 618 640 617 640 0.96

5 13 0.17 18 6.4 0.7 1 23 656 680 656 680 0.92

6 13 0.012 1.3 10.0 1.8 1 21 727 747 727 752 0.95

7 13 2.4e-05 0.0025 18.5 0.6 1 23 812 833 812 833 0.98

8 13 0.00077 0.081 13.7 0.1 1 21 839 859 839 860 0.95

9 13 5.2e-05 0.0055 17.4 3.1 1 23 879 901 879 901 0.98

10 13 0.0039 0.42 11.5 0.1 1 23 906 931 906 931 0.93

11 13 0.021 2.3 9.2 4.6 1 22 940 961 940 962 0.91

12 13 0.084 8.9 7.3 0.7 3 23 976 998 975 998 0.92

13 13 0.0014 0.14 12.9 1.2 1 21 1004 1024 1004 1029 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.7	5e+02	1.8	1.7	2	23	447	467	446	467	0.93
2	13	6.5	6.9e+02	1.4	4.2	1	23	499	523	499	523	0.92
3	13	0.00058	0.062	14.1	0.4	2	22	580	600	579	603	0.90
4	13	0.0041	0.43	11.5	0.6	2	23	618	640	617	640	0.96
5	13	0.17	18	6.4	0.7	1	23	656	680	656	680	0.92
6	13	0.012	1.3	10.0	1.8	1	21	727	747	727	752	0.95
7	13	2.4e-05	0.0025	18.5	0.6	1	23	812	833	812	833	0.98
8	13	0.00077	0.081	13.7	0.1	1	21	839	859	839	860	0.95
9	13	5.2e-05	0.0055	17.4	3.1	1	23	879	901	879	901	0.98
10	13	0.0039	0.42	11.5	0.1	1	23	906	931	906	931	0.93
11	13	0.021	2.3	9.2	4.6	1	22	940	961	940	962	0.91
12	13	0.084	8.9	7.3	0.7	3	23	976	998	975	998	0.92
13	13	0.0014	0.14	12.9	1.2	1	21	1004	1024	1004	1029	0.94

Sequence Information

Coding Sequence: ATGGAAAGTTACGAGGACGACGACGACACTCACTTCTGCATCAAATGCCATCTGACGATACACGGCCTCGACAATTACGTACGACATCGTCAATCCGGATGTCGGCCACCGGACGACAAGAACGTAGCCGTGCGGGTATCACCCACGACGCCCGCTTCGCCGACCACCGTTTTCTATCCGGAGATACTGAACGCGGACGCGTTCTTCAGTTCGCTGGAACTACAGAGCAGCTCCAAGTCGAATCCTCGAAAGGCATCCGGTTTGCTCGAGGAAAGTAGGAAGTTCAAGAAGGACGACAAAAGGAAAAAGAGTCAGAAATCGCAGGTGGACGCGGACGAATCGACGGTAAAAGAGAAGCTTCACAATATGTTGCCCGGAGTTTCGGAGCTCGAAAACCCCACCGACCATCTCTGCATGCCATCCCTCGTTGGATTTCCCGATATCGTTCCGTCCACGTCCAATAAGCCTACGGTTACGAGCAACCGGAACAAATTAAGTCAATCGATGAGCAACGTCGCCACGAACATCGACAGCGGCGGATTTTCGGTGAAGCCCGAGCCGGAAAATTCCTTGGAAGGTCTGATGACGTCTCAGGAATCCAAGCAGTCGGATAGAAAACGACAGGAAGAATCGCAAAGGATCGAACAGGTTCATCAAACGTGGTTGGAATACACGATATTGGCCGAGCTGGTGTCGAACAACGAAAACAAGGATCTGACCAGATACGAGTACGAATATCAACAGGACGAGGATTCCGAGGACGATATATTGGAGGAAGATTTGGGGGAGGATGACTCTTATACCGAGTCTGACGATGGGGAAGATCGAGAACGTCCACCGCGTGGTCACATCGGTGGCAAATGGAAGCCAGAATTGGACGATCTTCCTCAAAATATGTCTCAACTTCAGGACGACGACGTGGAGCCCGAAGACGAACATCAAGAACATCCGCCGCCGACTTATACAGGGGGCAAGTGGCGACCCTCGGACGCCTCGCAGAAGACGGAAGAATACGAGACTAAGAGCAACGTTGGACAACCATCGCCAGGACACACACGAGGGAAATGGGTACCGGGCGCACAAACGGATATCGAATCAGGATATTGGTGCAGTCCTTGCGGCAGGAAACTTGCCTCTCGATTGGTCTACAACAGGCATCTTCTCTCTGATTTGCACGCTAGAAGGAGCATCCGAGAAATCGATGGCGTTCTTTGCCTGCCGCGTGTCGCCAAGTTGCACGCACTGAAAAAATCATCGACTCGTATTCAAAAAACTAAAGAAGCGGAGGAAACGAAAGAAGCGAAGAAAAGTTTGCGAAAACGAGAAAAGGAAATACTTCGTTGCGAAATGTGCCATGCCCGAGTGAGAAGAACGCAAATGGGCAAGCATTTGCTCTCTCATTATCACTGCCGCGTGGCAGGTGTAAATCCTTGCAGCCCACGGGCGCGTCGCTTTTTACTAGAAAATATGGCGAATGTGGTTCGGCAGTGCCCTTTTCAGTGTTTCTCTTGTCGTTTTTACTGTAACACGGAGGAAACATTCCTGCGTCATTGGCGATCCGATCTTCACGCAAAAACGCTCGACCAGATCGCCGGCAGTTACAGATGCACTCCTTGCGACTTTTGGTGCGAGGACAACGAAACGATGGAAGCGCATCTGGTCGATTCGAGTCATCGCGACGTTGTTTCCATGATGAATGGTTCGGTGCCGATCATGATAGGTCGTCAGCGAGCTCTGACCTGCGGTGGTTGCGATCGTCGATTCCGGTATAATTTACAACTTCGATTGCACATCAAGGAAACTGGCCACGAAGAGAGTTTGACCGCGACGGACGAATATCAACAGCGAATCAAATGCAATCTGTGCCCGCAAATAGTTCGATCGTTGGTGGCACTTCAGCGTCACCAGTTGTCTTGCCACGTCACGAAGATCGAGAAACACGAGACGAACGATTCGCCCCAGCCTTATTTCTGTTCGTTCTGCTCGATGAACTTTGCCACTGCTCGAGAAGCCGTATTACATCGAAGAACGTCCAGTCACAAGGAGATAGTGAAGGCTCGGAAAAGCAGCGAAGGCCCGTCCACGTCCACGGTTCGGCAGTGTCCTCATTGCAAGCAGAAGCAGGCGAATTTATCGAAGCACAAGGCACACCTTCTCGATAATCATCCCGAGCTTTGTTACAGATGTCCCAAATGCGGTACGTTGTTTGCCCTCTCGCAAGACGTGACGAGGCACACGAGGGAAAACAAGTGCCATGTCTCAAACGATGAATCGAATAAAACGAAAACAGCGGACGCGAGAGACGAATGGAAATGCAACAGCTGTAGCTTCTCGACCAACATTCAAGCGGAATTTATCTTCCACGAAGCTCTTCACGCCGGGATCGTGCGAGGCGATAACGAAGACGAGAACTCTGGCAAATCATTGGCGAAGTATTCTTGCCCCATCTGCAAGAAGACATTCGCGAAAGTGTCATTACGGAATCACATCAGAAGCCACACCGGAGAGCGTCCGTTTCCGTGTGCCAAGTGTCTCGTGCCCTTTTCCAGGAGATCCGACCTAAACGCCCATCAGAAAGAGTGCACGGCTTCGACATCGTCGGGATGGTCGGAACGTTTGGAACGGAAACGAAGCTTTGTTTGTTCCGAGTGCAACAGCGCCTTCTACACAAAGCACTCGCTGCGACAGCATATGCTGCGCCACGCTGGGAAAAAGTACAAGTGCGGACTTCCGGGCTGTCCAACGGTGCTCCGAACAGCCTCCGAATTGAGATCGCACAGAACCTTGGTACACGACAGCACGCCGTCTAATAGACGATACAAGTGCTCCGATTGTTCTTACGCGGCCAAAACGAAGACTCAGTTACGACGACACTGCACTCGGCACGAAGAAGCAGGGAACGTGGCAAAATCAGAACTTCGCGCATGTCCCTACAGTGGTTGCGCTTTTAAAACGAAGCTCGCTTCTCATTTGCAGCGGCACGTGCGTCTCCACACGGGCACAAAGCCATACAAGTGTCGTCATTGTCCGTACGCCAGCAACAACTTGGAAAATCTAAGGAAACACGTGTTGTCCACGAACTTGCATCGGGGCAAGACGATCTACGAATGCGACGTTTGCCAAGAAGACAACCCGGAGCCGTTCCAGACGAATTTCGCGAAGGAGCTTCGCGCGCATCTGTTGGAAGTGCACAGCGACGCTTTTCCAACGCCTAACCACGCGAGCGATTACGTGGTCGGGATTTTTAAGGTTCGACGAGACTGTGACGAGTCAAATTAA
Protein Sequence: MESYEDDDDTHFCIKCHLTIHGLDNYVRHRQSGCRPPDDKNVAVRVSPTTPASPTTVFYPEILNADAFFSSLELQSSSKSNPRKASGLLEESRKFKKDDKRKKSQKSQVDADESTVKEKLHNMLPGVSELENPTDHLCMPSLVGFPDIVPSTSNKPTVTSNRNKLSQSMSNVATNIDSGGFSVKPEPENSLEGLMTSQESKQSDRKRQEESQRIEQVHQTWLEYTILAELVSNNENKDLTRYEYEYQQDEDSEDDILEEDLGEDDSYTESDDGEDRERPPRGHIGGKWKPELDDLPQNMSQLQDDDVEPEDEHQEHPPPTYTGGKWRPSDASQKTEEYETKSNVGQPSPGHTRGKWVPGAQTDIESGYWCSPCGRKLASRLVYNRHLLSDLHARRSIREIDGVLCLPRVAKLHALKKSSTRIQKTKEAEETKEAKKSLRKREKEILRCEMCHARVRRTQMGKHLLSHYHCRVAGVNPCSPRARRFLLENMANVVRQCPFQCFSCRFYCNTEETFLRHWRSDLHAKTLDQIAGSYRCTPCDFWCEDNETMEAHLVDSSHRDVVSMMNGSVPIMIGRQRALTCGGCDRRFRYNLQLRLHIKETGHEESLTATDEYQQRIKCNLCPQIVRSLVALQRHQLSCHVTKIEKHETNDSPQPYFCSFCSMNFATAREAVLHRRTSSHKEIVKARKSSEGPSTSTVRQCPHCKQKQANLSKHKAHLLDNHPELCYRCPKCGTLFALSQDVTRHTRENKCHVSNDESNKTKTADARDEWKCNSCSFSTNIQAEFIFHEALHAGIVRGDNEDENSGKSLAKYSCPICKKTFAKVSLRNHIRSHTGERPFPCAKCLVPFSRRSDLNAHQKECTASTSSGWSERLERKRSFVCSECNSAFYTKHSLRQHMLRHAGKKYKCGLPGCPTVLRTASELRSHRTLVHDSTPSNRRYKCSDCSYAAKTKTQLRRHCTRHEEAGNVAKSELRACPYSGCAFKTKLASHLQRHVRLHTGTKPYKCRHCPYASNNLENLRKHVLSTNLHRGKTIYECDVCQEDNPEPFQTNFAKELRAHLLEVHSDAFPTPNHASDYVVGIFKVRRDCDESN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684410;
90% Identity: iTF_00231595;
80% Identity: -