Bopu000910.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus opulentus
Gene Symbol
BAZ2B
Assembly
GCA_034509555.1
Location
CM067408.1:13843553-13856817[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.4e-22 4.5e-19 68.0 0.0 4 76 564 636 561 637 0.94

Sequence Information

Coding Sequence
ATGGAAATTCTAAAAGCGCAGCTAAAACCAAAGAAAAAGTCGCAGCGAAGGATTACGTATTGGCCTCGAGGCGACAGTGCAGCTTCGTCGCTATTCGGCGGAATGCCGGGCGGGTATGGATTGGGGGCCCATCATTTACCATCGGCTTATGCCATCTTGGGCCGTGGTGGCTCTGCTCCCGGATTCGGAGGCCACACACCAGCTTCCGCTCCACCACCACCTCCATACTCCCATAGCAGCCTTGGTACTCTGAGTGTAGCTGCTAGTCAGGCTGCGAGTTTAggTATCAATCCTGCTAGTGCAGCGTGGTGGACAATGGCCTCACATTTAGCTGCACAGGACTACCTCGCGAGGTTACAAGGAGCGGCAGGGCTACCCGGATTTCCGCCTGGTGCCGAGAGCCTTCTGCCACCCTATCCTGCCTCTCTACTTAATCCCCCGTCCCTATCGTCCCACAAGTCTAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACACCAGCGAGCAGTAGCAGTTCGACGACGCCGAGTATGACGGGCAGCAGTTTACCGGTTTCGACTCAAGCACCAGTCACGTCGTCTCATCACAGCACGTCGACCAGCAGCACGCCGAATTCGCAAACGAACGTTGTCAGcgATCCTAGCAGTATATTAGGAGGTGTACGCCTGCCACCTGATACGGAGATTATCAAGTACACGTCGAGCATAGTCGGTCCAAAGGTTCCTGGCACAACGAACCGCGGCAGGAAGAAGACTATATCCTTAGACACACCTAGCGTGAGTGTGCATCCACCGCCGGTACCTGCTCTCAGTGCTCATCAGACAAACACCACGACATCTTCGTTAATGATGGAACCGAGAAAATATAATCGCACGGGgACCGAGTCGAACGATTATAGGGAGTCGGTGGATCGCGTGGAGGTGATCAAACTGCCGGCACACTCGACAAACGGCTCTGCCTTACCAGCGCCATCGTCGTATACAACAACCACTAACGCGAGCAATTCGAACGATTCGGACGCGCCGCTGAACCTCTCGCTGAAACCCTCGACGACGAGCAGTAGCTCGCCGATTTCAGGCAGTCAGCCGCTCAGTCAGCTCAGTAATTTAAGTCAGTCGTTACTCGCCTCCGATAGAACTTCGAGAAGAAAGCCAGGACCGAAGCCTCGAAGGGTACCACAGAATTCCGTACCGGTGCCAGCATCGCCGAGTCCATCCTTGGCGCAGCTGTTCGCTGCAGCGGATTCACCTCAACGACCGAGCAGTGGAAGCGAGGAGAGCGAGAGCGCCAGCACGACCCACCACAAAGATGGTCGGCCGAGAAACTTGGGCCGTGGAGTATCTAAACCGAAGAAGAATACGGTGGCCTCGTTGCTAGCTCAGAGTAGAGCTTTGGGAATCAAACCGACGCCCACTTTGGATCCTAGTGTGCCATTGTCTCATCAGGTCTCGTTACTTAGGTCGAATATTCTGGCTGCTCAATTGCATGCCACTGCCACTGGCCAGACCGATGATAAGAATCAGCGGTCTTTACAGGAGAAGATGAAGAACAAGGTGCTCGAGGTATCCGGTGAGGAGAGTAACATGGACGTGACGAGCGAGAGCGGCAGCAACACCGACGTTGTGACGGACACCGACGACGACAACGCGGATGGCGTGTCTAGcgcgaagagaagaaaagtgAAGCCTAGCGAGAGGGATCTCCAGGTGCCGCTTGAGCGTGGCTGGAAGCGAGAGACCGTCATCAAGGGATTAGGAAAGTCAGGGGTGATAAAGGGTGACGTGTCTTATTATAGTCCTTGTGGAAAGACGTTCAGGAGTAGTCCGGATTTAGCGAAGTTTTTGGAGCAACAGAATCCACCCGACTTAACGACGGCAAACTTTTCCTTCTCGTCTCGTCCGCTTGTGGGTGAATTCCTGCAGCCAACGATGGGTCTCGCGGAGGCGGAATTCGTTAGGTTGGGCGCTCAGGAAGTTGCGAGAAGATTGGAGGAGTTGAGAGCCGCAGGTGGTTTCAGGGACGTGCGAACAAACAATCAGTACGAGAGGGAGAAACTGGCATATGCAAAAAAGCTAGCGAAAGAGGAGGCGCAACGACACAAGGAGCAAGCTAGGCTCATCAAGGAGCAAGAGAAAACGGAAAGGCAGGAGGCAGTGAGGCGAGAACGGGAGATTCGAAATCAACAGCTGCTCGAGGGTCGAAAGCGGCTAGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAACGCGGTAAGAGCAAGAGCGACGTGGCGCGCGAGCTGGGTCTGGCTAGCAGCACGGTGGCCACCATTTGGAAGAATCGGGAAAGCATCGCGGAGAGCTGGAGGAACCGCGACATGATGCAGCACTCTGATGTCGAGGACTCGGTCGCAAAAAAGTCCGGCCTGTCCTCATCATCGTCGAATTTGGCGTCCGTCACGTCGTTGGTGACGAACAATACGGTGTTAAACACCGTCAACACCACCAACAGTAGCACCACCGGCACCACGTTGCCCACCGCCATCGTGGTGGCACCGCCACAGGTGCAGGTGGTgccgccgccaccaccaccgccTCTCCCATTGCCGACCACCTCCGCCACGGTCGTCCCGTCGACGTCGCAACCGACGCAGCTCTCCACACCGCCAATCTCCAGCACCATGTCCACAggcaccaccaccaccaccaacGCCAGCATGGACAATACTCAGCAGGCCCAGACCCAGACGCAAAGTCAGGAGCTTCTGGAGGTAAGATGTCGTATGACGCCTCCCGACCCCTCACCGAAATACCCTCAGATAACTCGAAAAAAAATCGAGTTACCAACCCCAAAATTCTCTCCGCCCTCGATCATCCCTTTCAGGGGAACCTTCCATCGCGAGTCGCGTCCTCGAGGTTTTTTGCTCACATTCAGATGGAATTCACGATGGAATTGTGGTTGGTGA
Protein Sequence
MEILKAQLKPKKKSQRRITYWPRGDSAASSLFGGMPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSTTPSMTGSSLPVSTQAPVTSSHHSTSTSSTPNSQTNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPPVPALSAHQTNTTTSSLMMEPRKYNRTGTESNDYRESVDRVEVIKLPAHSTNGSALPAPSSYTTTTNASNSNDSDAPLNLSLKPSTTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHATATGQTDDKNQRSLQEKMKNKVLEVSGEESNMDVTSESGSNTDVVTDTDDDNADGVSSAKRRKVKPSERDLQVPLERGWKRETVIKGLGKSGVIKGDVSYYSPCGKTFRSSPDLAKFLEQQNPPDLTTANFSFSSRPLVGEFLQPTMGLAEAEFVRLGAQEVARRLEELRAAGGFRDVRTNNQYEREKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRREREIRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDMMQHSDVEDSVAKKSGLSSSSSNLASVTSLVTNNTVLNTVNTTNSSTTGTTLPTAIVVAPPQVQVVPPPPPPPLPLPTTSATVVPSTSQPTQLSTPPISSTMSTGTTTTTNASMDNTQQAQTQTQSQELLEVRCRMTPPDPSPKYPQITRKKIELPTPKFSPPSIIPFRGTFHRESRPRGFLLTFRWNSRWNCGW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00226594;
90% Identity
iTF_00220578; iTF_00226594; iTF_00223188; iTF_00219111; iTF_00216393; iTF_00221260; iTF_00230028; iTF_00962509; iTF_01169168; iTF_00676020; iTF_01418996; iTF_00218422; iTF_00225914; iTF_00228670; iTF_00227966;
80% Identity
iTF_00225234;