Basic Information

Insect: Bombus muscorum
Gene Symbol: Hr39
Assembly: GCA_963971185.1
Location: OZ020138.1:151505-160891[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3 2.7e+04 -5.7 5.5 138 160 44 66 22 90 0.42

2 5 3 2.7e+04 -7.0 10.9 79 164 319 402 247 449 0.53

3 5 3 2.7e+04 -11.3 16.2 45 148 397 514 373 541 0.51

4 5 1.5e-07 0.0014 18.8 0.1 1 19 608 626 608 645 0.94

5 5 6.9e-71 6.3e-67 227.4 0.2 88 408 666 985 628 985 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3	2.7e+04	-5.7	5.5	138	160	44	66	22	90	0.42
2	5	3	2.7e+04	-7.0	10.9	79	164	319	402	247	449	0.53
3	5	3	2.7e+04	-11.3	16.2	45	148	397	514	373	541	0.51
4	5	1.5e-07	0.0014	18.8	0.1	1	19	608	626	608	645	0.94
5	5	6.9e-71	6.3e-67	227.4	0.2	88	408	666	985	628	985	0.75

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCTGGACCGGGCCCAGGGCCGGGTCCCGGTTGGTGGCCAACCTCACAGTCCTGGAAAACGAACTCCTGCACCGCTGCTGCCTCCTCGTCCACTTGTTCGACCATTTCAGAAAACTCCGCCTCCGTCTCTGCCTCTTGCACCACCTCTACGTCCACCCTGGCGACCACCACATCGGCCACTTCGTCGACCAGCTGCTGTTCCTCCAGCCCTGGCGGTCCTGGTGGACCGTCTTGCACCATCACCGCGGCCCGCTCCTCCGAAACGGGAAAGAACGTCTCTGTCACGACGATCAATGTACCGCCTAATCAGGACATGCACGATGGCAAGGGTATATGCAAGTATCTTGGCGGCCAGAATGGCGTGACGGTATCGGTAGTGTCGAGCTGTGGCTCCGTACTGGGATGTGGAAACGCGAACGTTGTGTCTACCACGGGGATAGGCAATAGCACCGGCACACAGAGTATTGGCATCGGAGTGAACATCCTTGACCAGAGCACGGCGGATGATGACGCGGAGGATAGCGACGTTGAGATAAGCAAAATCGACTTCCGAGGGGTGAATTTGCgtacgaagaagaaacgagacgCGTCCGGTAGTCAGAGTCAAAGCGGGGAGAAAATCGGCGATGGAGAGGCGGAGGATGCGAACGGTTGTTACGATGGAAGCGACGCGTCTCAGCAACAACCGGAGAGGCCTATGTCATGGGAGGGAGAACTATCCGATCAAGAAATGTCTTCCAATACGATTACAAATCAAGATACGCACGAGGACACGTCGATGGAGGGTGTTCAAGTATGCGGCACGAGTCCCGGACCAATGGAACaaaaatttcccataaaaCCAGAGCCAGATTTTCAGTCCAACCCAGGTTTCACGTTTGGATCTTTTCACGACACCGGATTACCTCTGAATCACGGCCAGCAAatacaacaacagcaacaacagcgCAACATCGAGAATCTCGAACAGACGCAACAAAACGATTTGCCTCTTCTCGTAGGAAAGTTACTTGGCGGTTACAATAGTTCGACTCCGAATCACAGTCCAGTGTTGAATCCTAGACACCATCTAACGAAGCATAGCCACACGAGATCGCAGGTGCCGTCACCGGACTCGGCCATTCATTCCGCATACAGCGTATTCAGCTCCCCGACGCAAAGTCCTCACGCAACTCGCCACTCCCCCCTGGGCGCGGCGAGTCCAGTTCCATCTTCGTCGCTATCCTTGTCGCGACACAGTTTCAACAATTCCACATCCTCGTTGTCGCTCTCGTTGTCACACTCCCTCTCGAGAAACAATTCGGACGCCTCGAGCAGCTGCTACAGCTACGGCTCTCTCAGCCCGCCCACGCACTCGCCCGTCCAGCAACCGAGACATCCGCAGCATCACCAGCATCAAGTTGCTCAAGGAAGCCCGCTTCATCTGCCAGCGACCGCTTCTCCCGCCGTTACTCATCACTACAATTCCACTGCACCGGGTTCCGAGCTATCTCCGGAAGGATACGTTGCAGACGATCAGGAAGACTGTAGAATACCCTCGGCACCGTCCGGTATATCCACGAGGCAGCAACTAATTAATACCCCGTGTCCAATTTGCGGGGATAAGATCAGTGGTTTTCATTATGGAATATTCTCGTGCGAGTCGTGCAAGGGATTTTTCAAACGCACCGTCCAGAATCGAAAGAATTACGTGTGCCTTAGAGGCGCGGGCTGTCCAGTCACCGTTGTTACCAGGAAAAAATGCCCCGCCTGCAGATTCGAGAAGTGCCTCAATATGGGTATGAAGCTCGAGGCGATCAGGGAGGATCGCACCAGGGGTGGCAGAAGTACCTATCAGTGTACATATACTTTTCCACCGAATTTTGTCGGTAGTTCTGCGAGTAACATGGCCAGCGACAAATTAGCTAGCGGAGGAAATTGTAGTCCGGCTCCGGCTGGTAACGAACATCACTATGCGGCAAGGCACCATTCGAATCACTCCCATAAGATGCAAGTGGTACCGCAACTTCTACAGGATATCATGGACGTAGAGCACTTGTGGCATTACAACGATAACGATCGTATGACTGGGATTCAAAACGCAGGAACGAATTTTACTAGAAACAACGATTCAATGTTATTGAACGTTAGAAGCAACGGAGGATCTGGAATAGAGAACGACACGGGTTCGGGTATCGAGTGTTCCTCCAATAGAACTACAGGGAATGGTAATCCTAGCAATAGGAGAGATAACAGGTCATGCTCCAATGTTTCTAACGTTGGTAACGAACAACATGCTACACCCGTTGGTAACAGTTCTCAAATCAACAATACGAATTGCAATCCAACTCAACATCCTGATTTTCTGTCGAACCTCTGCAATATCGCTGATCATCGACTCTACAAAATAGTGAAGTGGTGCAAGAGTTTGCcgttatttaaaaacatttcgaTCGATGATCAGATCTGTCTGTTGATTAATTCTTGGTGCGAGCTACTGCTCTTCTCGTGCTGCTTTCGCAGTATGAGCACTCCCGGTGAAATTAGAGTGTCTCTCGGTAAGTCGATTACACTGGAACAAGCTAGGCAGCTTGGCTTGGCGACCTGCATCGAGAGGATGCTTGCGTTTACTAACAATTTGAGAAGGCTCCGAGTAGATCAGTACGAATACGTGGCGATGAAGgTAATAGTACTGTTGACCTCTGATACGAGTGAACTGAAAGAACCTGAAAAAGTTAGAGCATCTCAGGAAAAGGCTTTACAAGCATTGCAACAATATACTATCGCAAGGTATCCAGAAATGCCAGCTAAGTTTGGTGAATTATTATTGAGAATTCCAGATTTACAAAGAACATGCCAAGCAGGAAAGGAATTATTAAGTGCTAAACGTGCCGAAGGAGAAGGCAGCTCGTTTAATCTGTTGATGGAATTGTTGAGAGGAGATCATTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPGWWPTSQSWKTNSCTAAASSSTCSTISENSASVSASCTTSTSTLATTTSATSSTSCCSSSPGGPGGPSCTITAARSSETGKNVSVTTINVPPNQDMHDGKGICKYLGGQNGVTVSVVSSCGSVLGCGNANVVSTTGIGNSTGTQSIGIGVNILDQSTADDDAEDSDVEISKIDFRGVNLRTKKKRDASGSQSQSGEKIGDGEAEDANGCYDGSDASQQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGTSPGPMEQKFPIKPEPDFQSNPGFTFGSFHDTGLPLNHGQQIQQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHATRHSPLGAASPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASPAVTHHYNSTAPGSELSPEGYVADDQEDCRIPSAPSGISTRQQLINTPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVVTRKKCPACRFEKCLNMGMKLEAIREDRTRGGRSTYQCTYTFPPNFVGSSASNMASDKLASGGNCSPAPAGNEHHYAARHHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRMTGIQNAGTNFTRNNDSMLLNVRSNGGSGIENDTGSGIECSSNRTTGNGNPSNRRDNRSCSNVSNVGNEQHATPVGNSSQINNTNCNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_00228733;
80% Identity: iTF_00223253;