Bign015206.1
Basic Information
- Insect
- Bombus ignitus
- Gene Symbol
- Lztr1
- Assembly
- GCA_014825875.1
- Location
- CM026150.1:5822887-5826155[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3.3e-12 1.2e-09 38.6 0.7 2 108 351 494 350 496 0.87 2 4 4.6 1.7e+03 -0.5 0.0 77 108 495 526 492 527 0.89 3 4 1.4e-19 5.2e-17 62.3 0.0 9 95 588 674 580 690 0.84 4 4 0.85 3.2e+02 1.8 0.0 76 100 689 713 685 722 0.80
Sequence Information
- Coding Sequence
- ATGGATAACGTTGCGACAGCAGAGTGTTTGACTCTTGATTTTGGTCCTTTTGAAACTGTTCATCGCTGGCAACGGATGCTAGAATGTGACGAATTCGTTGGTGCCAGGCGTAGCAAACACACTGTTGTAGCATACAAAGATGCGATCTATGTTTTTGGTGGTGATAATGGTAAAAGAATGTTGAATGATTTATTGAGATTTGATGTAAAAGAAAAGTCCTGGGGACGTGCATTTGCAACAGGAATACCTCCTGCTCCAAGATATCATCATTCTGCAGTTGTGTATGACTCGTCTATGTTTGTATTTGGTGGTTATACTGGTGACATACATTCCAATTCGAATCTCACAAATAAGAATGACCTATTTGAGTACCGATTCCAAACTGGTCAATGGATACAATGGAAATTTATTGGAAAAACTCCTGTGGCTAGATCTGCACATGGAGCTGCTGTATATAATAATAAATTATGGATATTTGCTGGTTATGATGGTAATGCGAGATTAAACGATATGTGGACAATATCATTATTACCTGGAGAACCAAGAGTGTGGGAAGAGGTTGTTCAGTCTGGCGACTGCCCACCAACATGTTGTAACTTTCCTGTTGCAGTAGCACGCGAATCCATGTTTGTATTCAGTGGCCAGAGTGGAGCTAAGATCACAAATAGTCTCTTTCAATTCCACTTTCGAGAAAGGCGATGGACGCGAATTTCAACGGAGCATATACTTCGTGGTGCACCACCTCCACCAGCGCGACGATATGGTCACACCATGGTTAGTTTTGATAGACATCTTTACGTGTTTGGCGGCGCAGCTGATTCTACGTTACCCAACGATCTTCACTGCTATGATCTCGATACGCAAACATGGAATATTATTTTGCCATCTGCTGATAGTCAGGTTCCTTCTGGTCGAGTGTTTCACGCAACAGCGGTAATCGGAGAAGCAATGTTCATTTTCGGTGGAACAGCCGACAATAATGTCCGATCTGGGGAAACGTACCGATTCCAATTTTCGTCTTATCCAAAATGTACTTTACATGATGATTTTGGAAAATTTTTGAACAAGCGCCTTTTCTGTGATGTAGAATTTATAGTAGGAGATGCAGAAACCAAAATACCTGCTCACATAGCTATGGTAGCGGCTCGTTCACAATTTCTTAGGAAGCGCATTAGGCAAGCTCGAAAGAAACGAGATAAACATTTACAGGAAGTTTTTGGAACTGCAGATGTACCAATCAAAGATATGCCATTGTTAGAAGTAAAACTGAAAGATGCTGTCCCAGAGGCATTTGAGATGGCTCTTAACTATATTTATACCGATCGTATCGATCCAACAAAAAGAAGTGAAGATGGGTCGAGTAGTCGTGTCGAAGACCCATTAAGCAATCGAATTGTGCTTCTTATGATGGATGTTTATCGTTTAGCTTTGCAATTTAATATGAAACGATTGGACCAGTTGTGCGTTCAATATTTGAAAGCAACTATAAGTCGCGCTAACGTTTTAGAAGCATTGCATAACGCCGTTCAATTAAAATTATATTTTATAAAGGAGTTTTGCTTGAGTTTCATTGTAAAAGAAGTCAATTACAATCAAATTGTAATGAGCAAGGAATTTGAGACCTTGGATCAACCTTTGATGGTAGAAATTATTAGAAAAAGACAAATGCCTCAAAAAGATTTATTTCCTAGGCAGTGCGATCTTACTACAGGGACGACTTTGGAACAGGACATGGAGGCATTTCTTAAAAGTGTGGGCAGAGAATTCTGTGATATAACGCTTATGTTGGATGGCGTGCCGATTCCAGCCCACAAGGCCATTCTCGCGGCGCGTTGTAACTATTTTGAGGGAATGTTTCGCTCTTTTATGCCTGAAAATAATACAGTAAACATACAAATCGGTGAAATGATTCCATCTTCCGAGTCATTCCACTCCTTATTAAGGTATATTTACTATGCGGACGTTTCAATGCCGCCTGAAGACTCTTTATATTTATTTAACGCGCCAGCTTTTTATGGTTTTGCAAATAATCGATTGCAAGCGTTTTGCAAACAGAATCTTGAGATGAATGTCACTTTTGAGAACGTCATACAAATCTTGGAAGCTGCGGATAGGATGCAAGCTGTTGACATAAAGAAATACGCATTGAATCTTATTGTGCATCACTTTACGAAGGTTGCAAGGCTACCAAGGTTGAAGCAATTGAGTCGTGAACTTTTATTGGATATCTTAGGAGTATTGGCTGATGAACGCAGCGAGGCACGAACATGTCAGAACATGGAAAATGATTGCTGA
- Protein Sequence
- MDNVATAECLTLDFGPFETVHRWQRMLECDEFVGARRSKHTVVAYKDAIYVFGGDNGKRMLNDLLRFDVKEKSWGRAFATGIPPAPRYHHSAVVYDSSMFVFGGYTGDIHSNSNLTNKNDLFEYRFQTGQWIQWKFIGKTPVARSAHGAAVYNNKLWIFAGYDGNARLNDMWTISLLPGEPRVWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFRERRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFGGAADSTLPNDLHCYDLDTQTWNIILPSADSQVPSGRVFHATAVIGEAMFIFGGTADNNVRSGETYRFQFSSYPKCTLHDDFGKFLNKRLFCDVEFIVGDAETKIPAHIAMVAARSQFLRKRIRQARKKRDKHLQEVFGTADVPIKDMPLLEVKLKDAVPEAFEMALNYIYTDRIDPTKRSEDGSSSRVEDPLSNRIVLLMMDVYRLALQFNMKRLDQLCVQYLKATISRANVLEALHNAVQLKLYFIKEFCLSFIVKEVNYNQIVMSKEFETLDQPLMVEIIRKRQMPQKDLFPRQCDLTTGTTLEQDMEAFLKSVGREFCDITLMLDGVPIPAHKAILAARCNYFEGMFRSFMPENNTVNIQIGEMIPSSESFHSLLRYIYYADVSMPPEDSLYLFNAPAFYGFANNRLQAFCKQNLEMNVTFENVIQILEAADRMQAVDIKKYALNLIVHHFTKVARLPRLKQLSRELLLDILGVLADERSEARTCQNMENDC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00087267;
- 90% Identity
- iTF_00216471;
- 80% Identity
- -