Bhor012283.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus hortorum
Gene Symbol
-
Assembly
GCA_905332935.1
Location
HG995192.1:3252701-3260213[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.14 15 6.5 6.7 1 23 79 101 79 101 0.97
2 25 6.5e-06 0.00069 20.2 2.0 1 23 107 129 107 129 0.98
3 25 0.092 9.8 7.1 1.9 1 23 136 159 136 159 0.94
4 25 3.8e-06 0.00041 20.9 1.3 1 23 165 187 165 187 0.97
5 25 1 1.1e+02 3.8 3.9 2 20 193 211 192 215 0.82
6 25 1.1e-05 0.0012 19.5 2.4 1 23 222 244 222 244 0.97
7 25 2e-07 2.1e-05 25.0 1.0 1 23 248 270 248 270 0.99
8 25 0.035 3.8 8.4 1.1 1 23 276 298 276 298 0.94
9 25 5.5e-06 0.00058 20.4 0.6 1 23 304 326 304 326 0.99
10 25 5e-06 0.00053 20.5 1.2 1 23 459 481 459 481 0.98
11 25 0.34 36 5.3 2.8 2 23 487 508 486 508 0.96
12 25 7.3e-05 0.0078 16.9 1.1 1 23 515 538 515 538 0.97
13 25 4.8e-06 0.00051 20.6 2.7 1 23 544 567 544 567 0.93
14 25 0.0025 0.27 12.1 3.4 2 22 573 593 572 597 0.92
15 25 0.0001 0.011 16.4 6.1 1 23 630 652 630 652 0.98
16 25 2.3e-05 0.0025 18.4 0.5 1 23 656 678 656 678 0.97
17 25 0.00013 0.014 16.0 1.4 1 23 808 831 808 831 0.96
18 25 1.7e-05 0.0018 18.9 5.0 1 23 837 859 837 859 0.98
19 25 0.015 1.6 9.6 7.6 1 23 868 891 868 891 0.94
20 25 0.0012 0.12 13.1 1.2 1 23 897 919 897 919 0.95
21 25 1.6e-05 0.0017 19.0 2.4 1 23 924 947 924 947 0.96
22 25 0.00099 0.11 13.3 0.9 1 23 953 975 953 975 0.98
23 25 7.8e-08 8.3e-06 26.2 0.7 1 23 979 1001 979 1001 0.99
24 25 0.0009 0.096 13.4 7.4 1 23 1007 1029 1007 1029 0.99
25 25 6.5e-05 0.007 17.0 3.2 1 23 1035 1057 1035 1057 0.97

Sequence Information

Coding Sequence
ATGAAGGAACCGCCACCGGGTTCCACCGAAGAAAAGAAGGCTCAACCAGCAAAAGAAGACGGCGTTCATTCAACAAAGACAAATCAGACAGAAGAAAAAATAAAGGACGATTCAAGTAGCAACGATTCCTTTGAAGATCTCGACGACGCCCCCTTGGACTTCCGAAAGAGAGAACAGGAGCAAGAACAGGAGAAAAATAAATCTGTGAAACCAATACTCCCTAAGAAGAAAGTACACACGTGCGAGATCTGTTACGCGACTTTCGATCGTAAAAGTAAACATACGCGGCACATGTTCAAGCACAGTAACTCGAGACCTCATAAGTGTCCTATTTGCGCGAAAGGATTCAAAACCACAGCTCATCTAAGCAGGCACATGGAGGTTCACGATGAACCGGTAAACCTACATGCATGTAGTCTGTGTGACTTCAAAGCACGCACCAAGCCTTATCTGAAGATCCATTATATCAGAAAGCACACAGAAGACTACAACTATAAATGCGAACAATGTGGGAAGATGTTTAAGGTACAATCGGATTATACGACACATGTGAAAGATCATGATACAGAGTCTTGCGTGTGTGATATCTGTGGCTCGTCTTATCCCAGCAAAAGCTCGCTGTACTTCCATAAGCATTACAAACACAAGACGAAGGTGAAGAAGTTCCCCTGTCAGACGTGTAAGAAGAAGTTCAAGACGCAGAAGAATTTAGATAACCATATGGAGCTGCACAAGATTAAATACGTTTGTGAACAATGCGGGATGGAATTTAAGACGAAATATGGTCTCACCAAGCATCTGAGGACTCATTCCGGGGAGAAGTCTTATTTGTGCGCGATTTGTGGGAAAACTTTTGGATGTCTCAGCTCACAGAAGATTCATCTATTGACGCACGTTGGCGAAAGGCCTTACGTATGCGACATTTGTGGTCAGAGTTTCACTCAGAGGTCACCCATGATGTTGCATCGCAGAAAGCACCCTGGGGTGCACCCACCACCTCCTCCCATTAAAATAACAAACCTGCTGCATGGTGTGCAAGACAAAATAATCGTGAACAAGAGTAGCAAGTCGACACAGCGTGATCCGCTCGAGCAAACGTACCTCGTGGTGCAAAACACCAACAAATACTTCCTCCTTCCCATGGAGCAGAAAACATCGGCAGAGAAACACGAAGAGTGCATTGCTGATGATATCACCATCAAGTTTGAGGAACAAGACATACCCGAAGACACGACTGAACAACAGCTAATCGAATCGCCTGAACGAAAAGATTTTAAAATTGACGAAACTGCTGAGGTACATACGAATCAATTTTCGCAGTCGTTGGACCAACGTTCCAATGGTTCTGAAAGTATAACGAGCAACGAGGAAACGTTTACTTGCGACTACTGTTTGAAGATGTTCAAGAAGAAGCCCGCATTGCAGAGGCATATAGAGACTCATAGTAAAGCACGGGTGGAATGTTCGGTGTGCCATCGACTCCTAAAGACCAAGAAGACGCTGAAGTTTCATATGATGCTGCACGAAGATACCGATAAAATATTCGAGTGTTCGGAATGCGGCTTTATATCGAAACGAAAGCAAAGTTTGACTCGTCATCAGATCAGGATGCACTCGAAGATCGCCCATTACAAATGTCCAATTTGCTCGAAGACGTTTAAATTTAACGGTGATCTTAAAAGACATCATGAAGCGAAACACGTGGTCGACCCATGTTATTGCGAGGTTTGTGGAAAATCGTATCAAAATAGTCATTTTCTTCGAGAGCACCGGCGCATATCCAAGGCACATAGAAACGCTTACACTCGTTTATGTTACGGGGGAATTTGGGATAATAAGAACATAGAGCGTGCGACCTCGCAAAACAAGGGTAAAGAGAAGCGAATATTTAATTGCTCCAAGTGCAAATGGCGATTCAGCAGCTGCAAGTTACTAAATAAGCACATGCAACGACATCTCCTCATTTTTAACTGTGACATTTGTGGAGCCGTGTTTAAGTATAAGGCTTCGTTTTTGAAGCATCAAGAATCGCACAAACAATCTGAACAGAAACCAACTCAGCACTTAACCCCGAAGAACAAAGCCATCGCTCCTAAGCAACCGAAAGATCAATTAAGAGCTTCTCGCAAACCATCGAGCATTCTTCAAAGAAGAATCGCGTTTCGAGCTTCGAAGAACCGCAAACGCAGAAGCAACGGGCGTCTGAACAACTCTTCTAGTCGCGCAGAAACGAAAAGTATTTCAACCAATAACACAAACTCCAAACATAGGAGAATAAACGACGACGAAACGACTTCGTCGAAAAATTCTACGAAGAAAAAGTCATCTTTAAATTTCAACAATCGTTCGAATCAATTGCAAAATAACGAGAAACAAAGTACACAACAAGAAGATCTATATAAGAAACTCAACGACGGTACTTATACCTGTGATATCTGCCAAACGACCTTCGAACAGAAGAGCAAGATCCTCCGTCATATTACCAGCAAGCACAGCTTCCACCGACCCTTCAAATGTTCAACTTGCGACAAAACCTTCAAGTACAAATGCGACTTGAAAGCTCATCGTCTAATCCATCAAGACGTCGACTCCAGTTTATTACATTGTTGCGACAAATGTGATTATCGCACGAAGACGAAGAACAATCTCAAGTCCCATTACATTAGAAGACACACGGACGATTATAAATTCGCGTGTGAACACTGTGGGAAGCGTTTCAAAATGGAATGGGACTTGAAATTCCACATTGGAACTCACAGCAATTCGCAGCACATGTGTGACATCTGTGGAAAATTTTACACGAGCAACTATTCTTTGTATAAGCACAGGAAAGTGGCTCATTTGAACGAATATAAGTTCCAATGTAACGTTTGCAATAAAAGGCTCTTGACACAGGAGAACTTGGACAATCATATGCAACAACACAGTAGAACGTACGAGTGTAAAGACTGTGGAAAGGTATTTGCATCAAAAAGGTATCTAGCGACTCATATGACTACACACACAGGCGTGAAACCGTATACTTGTCATATTTGCAAGAAAAACTTTAGAACGTCGCATATGAGAAATACGCATCTTTTAACGCATTCTACGGAAAGGCCACATATCTGTGATCTTTGTGGACAGTCCTTTAAGAGGAGATATTATATGATAGAGCATAGAAGGAAACATCCTGACGCTCATTTGTCTTCGCCTCCTGTGCCTCTTGGGAAAAAGAAAAACGTTACCGGCACTGTGACTGAATGCCAAGCAGAGATTTCGCTGTAA
Protein Sequence
MKEPPPGSTEEKKAQPAKEDGVHSTKTNQTEEKIKDDSSSNDSFEDLDDAPLDFRKREQEQEQEKNKSVKPILPKKKVHTCEICYATFDRKSKHTRHMFKHSNSRPHKCPICAKGFKTTAHLSRHMEVHDEPVNLHACSLCDFKARTKPYLKIHYIRKHTEDYNYKCEQCGKMFKVQSDYTTHVKDHDTESCVCDICGSSYPSKSSLYFHKHYKHKTKVKKFPCQTCKKKFKTQKNLDNHMELHKIKYVCEQCGMEFKTKYGLTKHLRTHSGEKSYLCAICGKTFGCLSSQKIHLLTHVGERPYVCDICGQSFTQRSPMMLHRRKHPGVHPPPPPIKITNLLHGVQDKIIVNKSSKSTQRDPLEQTYLVVQNTNKYFLLPMEQKTSAEKHEECIADDITIKFEEQDIPEDTTEQQLIESPERKDFKIDETAEVHTNQFSQSLDQRSNGSESITSNEETFTCDYCLKMFKKKPALQRHIETHSKARVECSVCHRLLKTKKTLKFHMMLHEDTDKIFECSECGFISKRKQSLTRHQIRMHSKIAHYKCPICSKTFKFNGDLKRHHEAKHVVDPCYCEVCGKSYQNSHFLREHRRISKAHRNAYTRLCYGGIWDNKNIERATSQNKGKEKRIFNCSKCKWRFSSCKLLNKHMQRHLLIFNCDICGAVFKYKASFLKHQESHKQSEQKPTQHLTPKNKAIAPKQPKDQLRASRKPSSILQRRIAFRASKNRKRRSNGRLNNSSSRAETKSISTNNTNSKHRRINDDETTSSKNSTKKKSSLNFNNRSNQLQNNEKQSTQQEDLYKKLNDGTYTCDICQTTFEQKSKILRHITSKHSFHRPFKCSTCDKTFKYKCDLKAHRLIHQDVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHIGTHSNSQHMCDICGKFYTSNYSLYKHRKVAHLNEYKFQCNVCNKRLLTQENLDNHMQQHSRTYECKDCGKVFASKRYLATHMTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSTERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKKNVTGTVTECQAEISL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00229487; iTF_00225373;
90% Identity
iTF_00225373;
80% Identity
-