Basic Information

Insect: Bombus difficillimus
Gene Symbol: Rreb1
Assembly: GCA_014737525.1
Location: JACXIT010000092.1:3526304-3533566[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0031 0.29 11.8 0.0 1 23 40 62 40 62 0.98

2 15 0.006 0.56 10.9 1.2 1 20 76 95 76 101 0.93

3 15 0.0099 0.93 10.2 0.0 1 23 196 220 196 220 0.95

4 15 0.062 5.8 7.7 3.0 2 23 226 248 226 248 0.95

5 15 1.6 1.5e+02 3.3 0.6 1 19 304 322 304 324 0.89

6 15 0.46 43 5.0 0.1 1 23 437 459 437 459 0.96

7 15 2.4e-05 0.0023 18.5 0.3 1 23 468 490 468 490 0.98

8 15 0.0011 0.1 13.3 2.8 1 23 496 519 496 519 0.97

9 15 0.00039 0.037 14.7 3.0 1 23 901 924 901 924 0.97

10 15 0.00057 0.053 14.2 0.1 3 23 1201 1221 1199 1221 0.97

11 15 0.5 47 4.9 6.0 1 23 1227 1250 1227 1250 0.97

12 15 0.0036 0.33 11.6 2.2 1 23 1288 1312 1288 1312 0.97

13 15 5.5 5.2e+02 1.6 7.4 1 23 1396 1419 1396 1419 0.96

14 15 0.0096 0.9 10.3 0.4 2 23 1470 1491 1469 1491 0.94

15 15 1.1 1.1e+02 3.8 8.2 1 23 1497 1519 1497 1519 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0031	0.29	11.8	0.0	1	23	40	62	40	62	0.98
2	15	0.006	0.56	10.9	1.2	1	20	76	95	76	101	0.93
3	15	0.0099	0.93	10.2	0.0	1	23	196	220	196	220	0.95
4	15	0.062	5.8	7.7	3.0	2	23	226	248	226	248	0.95
5	15	1.6	1.5e+02	3.3	0.6	1	19	304	322	304	324	0.89
6	15	0.46	43	5.0	0.1	1	23	437	459	437	459	0.96
7	15	2.4e-05	0.0023	18.5	0.3	1	23	468	490	468	490	0.98
8	15	0.0011	0.1	13.3	2.8	1	23	496	519	496	519	0.97
9	15	0.00039	0.037	14.7	3.0	1	23	901	924	901	924	0.97
10	15	0.00057	0.053	14.2	0.1	3	23	1201	1221	1199	1221	0.97
11	15	0.5	47	4.9	6.0	1	23	1227	1250	1227	1250	0.97
12	15	0.0036	0.33	11.6	2.2	1	23	1288	1312	1288	1312	0.97
13	15	5.5	5.2e+02	1.6	7.4	1	23	1396	1419	1396	1419	0.96
14	15	0.0096	0.9	10.3	0.4	2	23	1470	1491	1469	1491	0.94
15	15	1.1	1.1e+02	3.8	8.2	1	23	1497	1519	1497	1519	0.98

Sequence Information

Coding Sequence: ATGGACGACGCACGACGCTGTCTTACTGTTAAAAACGGACCCACCCAGGAAAATGAGAATGAAACACCAGCTGATGCTGCATCCTCACCATCCAGTGTTGAACTACCAGAAAGCGCATATCCATGTCCAGCTTGTTCGACCGTTTTGCCCACCTCCAGGGAGTTAACGAACCACCTACGCGGCCATAATTCGCCTCGCAGCACAGACTGTAGCGGCGAGGATGACTATTGCTGCGGCGTGTGCAATAAGGTGCTGAGCTCTGCAAGTTCCCTCGACAGACATGTGCATTTGAGGACAGCGCACAGAGGCGCCTCGCCTAACAGCTGCACCGACTCCGAGGGTAGCAGCGACTCGGACAAATCATCCAGGCAGCGACATCTCGAGGAATACAACAACAACGAGATCACAAAAAGAAACTCGCCAAATATCGAGGACAGACGGGACGAGGAACAGACCTCGTCGTTAACTGGAAAGAGAAAGTGCCCTAACTATACGAGCGACAACGAAACACAGAAGAGGCACAAGATTCTTCTAAATAGTTCGAGAAGCGAGATGAAGTCGAGACCGGACGACAACCAGAACATTTACAATTGTCCAGTATGCGGGCGACAGGATTTTGCCACTAGCGCCCTCTTAGAAGCGCATCTGGAACGAAGTCATCCAGAATTCCCCGCAAAATGCGACACGTGCAACTTGTCGTTCAAAAACCACAGAGTATTGAATCTGCATCGGTTCATGATACATTTCGCGGAACACTCGATGGGAAATACCGCGAGAAATCTGAGAAACTCGATAGTAGGTTTCAACGATTTAACGTTCGTTGATTTCTCGTCCGATAAGTTCCCAGCAATAGCGAGAGCTGTCTGCGAACAATCGCTTCACCGGCCAGCTTCTGGCGAGGTAACCAAATTCCAATGTTCCAAATGTCTGCGAGCATTCCCTTGTAGGTCCGCGTTGGACGCCCACGAAACTGACTGCGGCACGATGAATTTGCAAAGCAGAACAACCGACGATAGCCAATCGAGAAGAGACGATTTCTTCGCTGGCTTGGATCTTCAAAACAAGGCTGCTTTGAGGGAAGCGAAGGAAGGCAAAGATCTTGCCGATATCCAGAGTATCATATCTGTCACTTCTGGGCCCATTTTACAGAATTTTCGATCAGATGCCAGTACACCAGAGAATAACATCAAATTTAATAACAGCATAAATTCTTCTGGTAGTTCAAGTACGTACTGCGCAGAGTACCACGAGGAGGAAGCTCAAGACGCGTTTTCCGCGGAGTTCAGAAAAATGAAATTGAAAGGGGAGTTCCCTTGCAGGCTCTGTTCCTCAATATTTCCTAATCTAAGAGCCCTAAAAGGTCATAACAGGGCGCACATGGGCGTGGGACCTGGCATGCCATATCCTTGTAATATGTGCCCTTATACCAGCACTGATAAAGCGACTCTGGTGAGGCATCTGAGGTCTCACAATGGCGACAGACCTTACGAATGCTCTCTTTGCAATTACGCTTTCACAACCAAAGCAAATTGTGAGCGCCATGTACGAAACCGACATGGAAAATTGACAAGAGAAGACATTAAGAGCGTTCTCATTTATCATCCGAATGAAGATTCTACGAACGAAAACGTGGAACGTGGAAACTCACCTAGAGTTTTGAAGGATGAAGTGAGAAAGAGCCTCGTATATCCGCCAGAACGCGAAGAACTTCACCACCAGGCGCAAATACATTATCCTCCGGTTTCTATGGAGGCAAGAGGTGAGATCAGAATAATAGAAGAGGCGAAGCTGCAAAATTCCTCGATGTCGATATACAGCACTAGCCACTTTGAAAAAAATGATGCGTTTTCAAGGCATGGTCAGCCTTTGGAGCTGACTCAAAGGAACTCCGAGGAGACGAAACCTGGTCAAGATGCCAAATCGGATTATTCGAAGTTGGACGACGATTTGGAGTCGAGGTCGTCCGAGGGTAGCGTATCTCTAGTCACAGAAACCAAAACAGATTCGCACCAAAGAATACAAGCTAGTCCTATGAATTTAAAGAAAGGTCTCAACATATCGGAAAACATAGGCGAAGACGGTCCGTTGGACCTTTCCATGGACGTACTGGATCTCAGCAAGAAGTCGAAGGAGAAGGAGAACGATAACTTGGCCGCGGCTCACGAACAATTTGGAAAAAACCAAAAAGATTTGTACAGTGCTACCAGTCACTTATTGTTGACCGAGGCTTTGTTGAAGGCTGGCCAGGGTACCTCTCAATCTACATCTCTGGAAGCTCTGTACGCTAACGCAATCTACAGAAACTTCAGTACATTTCCTAGTAGCGTAGGAACTGGAATACTGCCACCGTACATGTTCAATCCTCATGTCTTTGGCCAGGATTTCGCTATGAAGGAAAGATTACAGAAGGAACTGGTTAGAGGTCTACAGTTGACGAGCGGAGGTACTTTGGTGGAGCCACCCATAGGTAGCGCGGGATTTACCACCTTCTCTCAAAATAGAGACATGAATTCTCAGTCTCATTCAACGACCGACCAAAGCGAATATGCCAAATTAATATCTTCTAAGATGGCCAACAAGAGTCTGACAACCCGCGATAAACCAGACAATCTGCCCTCGTCCAATTCTGTGAAGATGGTGATCAAAAATGGAGTCCTGATGCCTAAACAAAAGCAACGAAGGTACAGAACTGAGAGGCCGTTTACCTGTGAACATTGCTCAGCGAGATTTACTTTAAGGAGTAATATGGAAAGACACATTAAGCAACAACATCCTCAGCACTGGAGCCAGCGACCCAGAGGAGGTCACTCGACAAGGGGAAGACCACCTTCTAGCCATCCTACGCTGATTCAAAACCTTGGACAGTCGACTTCTCAAGGCAGTCAATCGTACAACAATATCCTGCCAAAAGTGGAACAGTCAACGAATCCGGAATTTACGAGGCATCCTATCTCCGACCAAGTAAAGTACGCTATACTAGCACAGCAATTAAAGGTAAACAAAATGGAAGACAACGATTCTGAAGAAGAATTGGTAATAGACGAAGGGCCCCAGGAAAAAGAAAATCAGGAATCTCAGGATCAAGGGGAGAAGAGTCTATTGAGAGGCCAATTGGAAGCTACAGAATCTACGAAAGAAATTGTAGTGAAAGAAGAAGCCATGGAATGTTCAAACGATGGCCCAAACGAGACAAATGTTGAGCTGGAGAATAACGAACAAAATGTTGCTGAACAACAGAAAAAATCTGACACGGAAAAGGTTACTGTGACGGAAAATTCGGTTGATAAGAATACTGACAGACTGCTCAAAACGGAAACAGTTAATGTGAAAAGCGAGAAGATGGAGGATGGAGCAACTGACCTCGCTAGCGTGTCAGAACTATTAGACAATGCCTCCCAACAATATCAGCAGTTTCAACCCCAGTATTTAAGCGACGAAGAAGGTCTGGTAGCATCGAACAGTGATTGCAATAATTCAGGTAGTGACGAGAAATCCGACTCCGTAAATTCATCACATTCGACGAACGCTTCGAAGAAAAAGAAGAAAAAGAAGAAAAAAAAGAAGAAATCGGCATATTCAATGGCCCCGAATAGAGTAATATGTCCATACTGCGAACGACCATTTCCATGGACCTCGTCTCTCAGACGACATATTTTGACACACACTGGGCAGAAACCGTACCAATGCGTTCACTGTTCGTTGCTATTCACAACGAAATCCAACTGTGACCGTCATTTGCTCCGAAAACATAAAGCAAATCCGAACAAGATGCGTAGAGTTAGAAACTCTTCTTCTCCAGATTCTCAAGCAGTCATCAACAATAGTAACTCGTTCTCCATGAGGAACGTCCCTGAAAGACCCTACAAGTGCAATCAGTGTCCCAGCTCAACATTTTCAACGTTGGGTAACCTAAAGAAACATCGTTCCACTAAACACGCTCGAAAGATGAAGACCAGGTCGGACACTCCGTCCAGTGAACCTCAAGCCAGCCCACAGGAGTGTCCAAAGCCGAATAACGAGCAAACTGATTATGATAGTCAGTCTTCGAGCGTGTCCGAAGGGATAGAAACTTCTTCGATGCCAGGGCTTACCAAATCGAATTCTAACGCTTCACAATTGGCCAACGAAACAGCTAGGTCAAGGAGACCTTCGCCAAGATCATCACCTGGGCCCAGTGATGTTCCTTTTAAGTGCCACTTATGCGACTGTGGTTTCGCAGAACGACACGACTGCCTCGAACACATCAAAATGAACCACAAAAAATCCTACGAAATGTTAGTGGCGAAAGGGGCACTGGACATGGACATCGACGCGGTCGAAGACCAGCAACAACCGCCGCCACAACATCATACCAGCGACGGAGAAGAAAAACGGGGACGTTTCCCAGACTATAGTAACAGGAAGGTTGTATGTGCATTCTGTATGAGGCGGTTCTGGTCTGCAGAGGATCTCCGACGCCATATGAGAACACACACCGGAGAACGACCTTTCTCCTGCGATATATGCTGCAGAAGATTCACCTTGAAGCATAGTATGCTGCGGCACAGAAAGAAGCACGAATCCATTGATTCTACCATGTATGTTGGTACAAGCGGAGATGAAGAAAACTCACCTACACAGCCACCTACGATTACACCACGAAGCCAACAGCAACAACAAATTCTGGTGACAGCTAACAACGGAAATTCCCGTATTCAAGACAGAATCTCTTTGCCAACTGTTACTCCAGTCGCGACCGGCGATGCAGCCCCGAGTGGATTAATAAGATTCAATCCATACGAGAAATTAACCACTCTGACAGGAAAATTGGCCAGTATTCCATCAAACGCAAATCCAGATGCAGAGAACACGGATAATGATTTGATCTCGAACCTGCTGGGAATAAGAGACAAGAGTTTTATCGACAGAGTACTACAGGCATCCGCGGATGACGCCGCCAAGCTATTAGGAGTAAAGCGTAGCCACGAATGA
Protein Sequence: MDDARRCLTVKNGPTQENENETPADAASSPSSVELPESAYPCPACSTVLPTSRELTNHLRGHNSPRSTDCSGEDDYCCGVCNKVLSSASSLDRHVHLRTAHRGASPNSCTDSEGSSDSDKSSRQRHLEEYNNNEITKRNSPNIEDRRDEEQTSSLTGKRKCPNYTSDNETQKRHKILLNSSRSEMKSRPDDNQNIYNCPVCGRQDFATSALLEAHLERSHPEFPAKCDTCNLSFKNHRVLNLHRFMIHFAEHSMGNTARNLRNSIVGFNDLTFVDFSSDKFPAIARAVCEQSLHRPASGEVTKFQCSKCLRAFPCRSALDAHETDCGTMNLQSRTTDDSQSRRDDFFAGLDLQNKAALREAKEGKDLADIQSIISVTSGPILQNFRSDASTPENNIKFNNSINSSGSSSTYCAEYHEEEAQDAFSAEFRKMKLKGEFPCRLCSSIFPNLRALKGHNRAHMGVGPGMPYPCNMCPYTSTDKATLVRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLTREDIKSVLIYHPNEDSTNENVERGNSPRVLKDEVRKSLVYPPEREELHHQAQIHYPPVSMEARGEIRIIEEAKLQNSSMSIYSTSHFEKNDAFSRHGQPLELTQRNSEETKPGQDAKSDYSKLDDDLESRSSEGSVSLVTETKTDSHQRIQASPMNLKKGLNISENIGEDGPLDLSMDVLDLSKKSKEKENDNLAAAHEQFGKNQKDLYSATSHLLLTEALLKAGQGTSQSTSLEALYANAIYRNFSTFPSSVGTGILPPYMFNPHVFGQDFAMKERLQKELVRGLQLTSGGTLVEPPIGSAGFTTFSQNRDMNSQSHSTTDQSEYAKLISSKMANKSLTTRDKPDNLPSSNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPSSHPTLIQNLGQSTSQGSQSYNNILPKVEQSTNPEFTRHPISDQVKYAILAQQLKVNKMEDNDSEEELVIDEGPQEKENQESQDQGEKSLLRGQLEATESTKEIVVKEEAMECSNDGPNETNVELENNEQNVAEQQKKSDTEKVTVTENSVDKNTDRLLKTETVNVKSEKMEDGATDLASVSELLDNASQQYQQFQPQYLSDEEGLVASNSDCNNSGSDEKSDSVNSSHSTNASKKKKKKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCVHCSLLFTTKSNCDRHLLRKHKANPNKMRRVRNSSSPDSQAVINNSNSFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHARKMKTRSDTPSSEPQASPQECPKPNNEQTDYDSQSSSVSEGIETSSMPGLTKSNSNASQLANETARSRRPSPRSSPGPSDVPFKCHLCDCGFAERHDCLEHIKMNHKKSYEMLVAKGALDMDIDAVEDQQQPPPQHHTSDGEEKRGRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKHESIDSTMYVGTSGDEENSPTQPPTITPRSQQQQQILVTANNGNSRIQDRISLPTVTPVATGDAAPSGLIRFNPYEKLTTLTGKLASIPSNANPDAENTDNDLISNLLGIRDKSFIDRVLQASADDAAKLLGVKRSHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00625690;
90% Identity: iTF_00214579;
80% Identity: -