Basic Information

Gene Symbol
-
Assembly
GCA_014737525.1
Location
JACXIT010000097.1:1082480-1087878[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.096 9 7.1 6.7 1 23 115 137 115 137 0.97
2 16 4.3e-06 0.00041 20.8 2.0 1 23 143 165 143 165 0.98
3 16 0.062 5.8 7.7 1.9 1 23 172 195 172 195 0.94
4 16 2.6e-06 0.00024 21.5 1.3 1 23 201 223 201 223 0.97
5 16 0.68 64 4.5 3.9 2 20 229 247 228 251 0.82
6 16 7.4e-06 0.00069 20.1 2.4 1 23 258 280 258 280 0.97
7 16 1.3e-07 1.2e-05 25.6 1.0 1 23 284 306 284 306 0.99
8 16 0.024 2.2 9.1 1.1 1 23 312 334 312 334 0.94
9 16 3.6e-06 0.00034 21.0 0.6 1 23 340 362 340 362 0.99
10 16 1.4e-06 0.00013 22.4 1.5 1 23 503 525 503 525 0.98
11 16 0.0031 0.29 11.8 2.3 2 23 531 552 530 552 0.96
12 16 0.00023 0.022 15.4 1.5 1 23 559 582 559 582 0.97
13 16 3.3e-06 0.00031 21.2 2.3 1 23 588 611 588 611 0.93
14 16 0.00014 0.013 16.1 5.5 2 22 617 637 616 641 0.92
15 16 1.8e-06 0.00017 22.0 2.7 1 23 674 696 674 696 0.98
16 16 1.6e-05 0.0015 19.1 0.5 1 23 700 722 700 722 0.97

Sequence Information

Coding Sequence
ATGGCATCTAGTAGGTACAATGCGCTAGATCCACTCGCCCCAACTTTTCTGATAGTAAAACTAGAAGATAATTACTTTCGGATACCGACGTCGCTGAGTGTGTTCATGATGAAGGAACCGCCACCGGGTTCCACCGAAGAAAAGAAGGCTCAACCAGCGAAAGAAGATGGCGTTCATTCGACAAAGACAAACGAGACAGAAGAAAAAATAAAGGACGATTCAAGTAGCAACGATTCCTTCGAAGATCTCGACGACACCCCCTTGGATTTCCGAAAGAGAGAACAGGAGCAAGAACAGGAGAAAAATAAATCTGCGAAACCAATACTCCCTAAGAAGAAAGTACACACGTGCGAGATCTGTTACGCGACTTTCGATCGTAAAAGTAAACATACACGGCACATGTTCAAGCACAGTAACTCGAGACCTCATAAGTGTCCTATTTGCGCGAAAGGATTCAAAACCACAGCTCATCTAAGCAGGCACATGGAGGTTCACGATGAACCGGTAAACCTACATGCATGTAGTCTGTGTGACTTCAAAGCACGTACCAAGCCTTATCTGAAGATCCATTATATTAGAAAGCACACAGAAGACTACAACTATAAATGTGAACAATGTGGAAAGATGTTTAAGGTACAATCAGATTATACGACACATGTGAAAGATCATGATACAGAGTCTTGCGTGTGTGATATCTGTGGTTCGTCTTATCCCAGCAAAAGCTCGCTGTACTTCCATAAGCATTACAAACACAAGACGAAGGTGAAGAAGTTCCCCTGTCAGACATGTAAGAAGAAGTTCAAGACGCAGAAGAATTTAGATAACCATATGGAGCTGCACAAGATTAAATACGTTTGTGAACAATGCGGGATGGAATTTAAAACGAAATATGGCCTCACCAAACATCTAAGGACTCATTCCGGGGAGAAGTCTTATTTGTGCGCGATTTGTGGGAAAACTTTTGGATGTCTCAGCTCACAGAAGATTCATCTGTTGACGCACGTTGGCGAAAGGCCTTACGTATGCGACATTTGTGGTCAGAGTTTCACCCAGAGATCGCCCATGATGTTGCATCGCAGAAAGCATCCTGGGGTGCACCCACCACCTCCTCCCATTAAAATAACGAACCTGCTACACGGTGTACAAGATAAAATAATCGTGAACAAGAGTAGCAAGTCGACACAACGTGATCCGCTCGAGCAAACGTACCTCGTGGTGCAAAACGTCGACAAATACTTCCTCCTTCCCATGGAGCACAAAACATCGATACAGAAACACGAAGAAGAGTGTATTACTGGAGATATCACCATCAAGTTGGAGGAACAAGACATACCCGAAGACACGACCGAACAACAGCTAATCGAATCGCCTGAGCGAAAAGATTCTCAAATTGACGAAACTGCTCAGGTACATACGAATCTATCTGTTCAGACGCCTGTACAATTTTCTCAGTGGTTGGACCAATGTTCCAATGGTTCTGAAAGTATAACGAGCAACGAGGAAACGTTTATTTGCGACTACTGTTCGAAGATCTTCAGGAAGAAGTACGCGTTACAAAGGCATTTAGAGACTCATAGCAACGCACGGGTGGAATGTTCGGTGTGCCATCGACTCCTAAAGACCAAGAAGACGCTGAAGCTTCATATGATGCTGCACGAAGATACCGGTAAAATATTCGAGTGCTCGGAATGCGGCTTTATGTCGAAACGAAAGCAAAGTATGACTCGTCATCAGATCAGGATGCACTCGAAGATCGCCGGTTACAAATGTCCACTTTGCCCGAAGACGTTTAAATTTAACGGTGATCTTAAAAGACATCATGAAGCGAAACACGTGGTCGACCCATGTTATTGCGAGATTTGTGGAAAAACGTATCGAAATAGTCATTTTCTTCGGAAGCATCGGCGCATATCCAAGACACACAGAAACGCTTACACTCGTATATGTTACGGGGCAATTAGGGGTAATCAGAACATAGAGTGTGCAACCTCGCAAAACAAGGGTAAAGTGAAGCGAATATTCAATTGCTCCAAGTGCAAATGGCGATTCAGCAGCTGGAGGTTACTAAATAAGCACATGCAACGACATCTCCTCATCTTTAACTGCGATATTTGTGGAGCCGTGTTTAAGTATAAGGCTTCGTTTTTGAAGCATCAAGAATCGCACAAACAATCTGAACAGTTTTAA
Protein Sequence
MASSRYNALDPLAPTFLIVKLEDNYFRIPTSLSVFMMKEPPPGSTEEKKAQPAKEDGVHSTKTNETEEKIKDDSSSNDSFEDLDDTPLDFRKREQEQEQEKNKSAKPILPKKKVHTCEICYATFDRKSKHTRHMFKHSNSRPHKCPICAKGFKTTAHLSRHMEVHDEPVNLHACSLCDFKARTKPYLKIHYIRKHTEDYNYKCEQCGKMFKVQSDYTTHVKDHDTESCVCDICGSSYPSKSSLYFHKHYKHKTKVKKFPCQTCKKKFKTQKNLDNHMELHKIKYVCEQCGMEFKTKYGLTKHLRTHSGEKSYLCAICGKTFGCLSSQKIHLLTHVGERPYVCDICGQSFTQRSPMMLHRRKHPGVHPPPPPIKITNLLHGVQDKIIVNKSSKSTQRDPLEQTYLVVQNVDKYFLLPMEHKTSIQKHEEECITGDITIKLEEQDIPEDTTEQQLIESPERKDSQIDETAQVHTNLSVQTPVQFSQWLDQCSNGSESITSNEETFICDYCSKIFRKKYALQRHLETHSNARVECSVCHRLLKTKKTLKLHMMLHEDTGKIFECSECGFMSKRKQSMTRHQIRMHSKIAGYKCPLCPKTFKFNGDLKRHHEAKHVVDPCYCEICGKTYRNSHFLRKHRRISKTHRNAYTRICYGAIRGNQNIECATSQNKGKVKRIFNCSKCKWRFSSWRLLNKHMQRHLLIFNCDICGAVFKYKASFLKHQESHKQSEQF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00228336;
90% Identity
iTF_00215167;
80% Identity
iTF_00219475;