Basic Information

Insect: Bombus cullumanus
Gene Symbol: BAZ2B
Assembly: GCA_014737535.1
Location: JACXIX010000023.1:3575323-3586498[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.4e-23 4.5e-19 67.9 0.0 4 76 530 602 527 603 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.4e-23	4.5e-19	67.9	0.0	4	76	530	602	527	603	0.94

Sequence Information

Coding Sequence: ATGCCGGGCGGGTATGGATTGGGGGCCCATCATTTACCATCGGCTTATGCCATCTTGGGCCGTGGTGGCTCTGCTCCCGGATTCGGGGGCCACACACCAGCTTCCGCTCCACCACCACCTCCATACTCCCATAGCAGCCTTGGTACTCTGAGTGTAGCTGCCAGTCAGGCTGCGAGTTTAGGTATCAATCCTGCTAGTGCAGCGTGGTGGACAATGGCCTCACATTTAGCTGCACAGGACTACCTCGCGAGGTTACAAGGAGCGGCAGGGCTACCCGGATTTCCGCCTGGTGCCGAGAGCCTTCTGCCACCCTATCCTGCCTCTCTACTTAATCCCCCGTCCCTATCGTCCCATAAGTCTAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACGCCAGCGAGCAGTAGCAGCTCGACGACGCCGAGTATGACGGGAAGCAGTTTACCAGTTTCGACTCAAGCACCAGTCACGTCGTCTCATCACAGCACGTCGACCAGCAGCACGCCGAATTCGCAAACGAACGTTGTCAGCGATCCTAGCAGTATATTAGGAGGTGTACGCCTGCCACCTGATACGGAGATTATCAAGTACACGTCGAGCATAGTCGGTCCAAAGGTTCCTGGCACAACGAACCGTGGGAGGAAGAAGACTATATCCTTAGACACACCGAGTGTGAGTGTACATCCACCGCCGGTACCTGCTCTGAGTGCTCATCAGACAAACACCACGACATCTTCCTTAATGATGGAACCGAGAAAATATAATCGCACGGGGACCGAGTCGAACGATTATAGGGAGTCGGTGGATCGCGTGGAAGTGATCAAACTGCCGGCACACTCGACAAACGGCTCTGCCTTACCAGCGCCATCGTCGTATACAACAACCACCAACGCGAGCAATTCGAATGATTCGGACGCGCCGCTGAACCTCTCGCTGAAACCCTCGACGACGAGCAGTAGCTCGCCGATTTCAGGCAGTCAGCCGCTCAGTCAGCTCAGTAATTTAAGTCAGTCGTTACTCGCCTCCGATCGAACTTCGAGAAGAAAGCCGGGACCGAAGCCTCGAAGGGTACCACAGAATTCCGTACCGGTGCCAGCATCGCCGAGTCCATCCTTGGCGCAGCTGTTCGCTGCAGCGGATTCACCTCAACGACCGAGCAGCGGAAGCGAAGAGAGCGAGAGCGCCAGCACCACCCACCACAAGGATGGTCGACCGAGAAACTTGGGCCGCGGAGTATCCAAACCGAAGAAGAACACGGTGGCCTCGCTGCTAGCTCAGAGTAGAGCTTTGGGGATCAAACCGACGCCCACTTTGGATCCTAGTGTGCCATTGTCTCATCAGGTCTCGTTACTTAGATCGAATATTCTGGCTGCTCAATTGCATGCCACTGCCACTGGCCAGACTGATGACAAGAATCAGCGGTCTTTGCAGGAGAAGATGAAGAACAAGGTGCTCGAGGTATCCGGCGAGGAGAGTAACATGGACGTGACGAGCGAGAGCGGCAGCAATACCGATGTTGTGACGGACACCGACGACGACAACGCGGATGGCGTGCCTAGCGCGAAGAGAAGAAAAGTGAAGCCTAGCGAGAGGGATCTCCAGGTGCCGCTTGAGCGTGGCTGGAAGCGAGAGACCGTCATCAAGGGATTAGGAAAGTCAGGGGTGATAAAGGGTGACGTGTCTTATTATAGTCCTTGTGGAAAGACGTTCAGGAGTAGTCCGGATTTGGCGAAGTTTTTGGAGCAACAGAATCCACCCGACTTAACGACGGCAAACTTTTCGTTCTCGTCTCGTCCGCTTGTGGGTGAATTCCTGCAGCCAACGATGGGTCTCGCGGAGGCGGAATTCGTTAGGTTGGGAGCTCAGGAAGTTGCGAGAAGATTGGAGGAGTTGAGAGCCGCAGGTGGTTTCAGGGACGTGCGAACAAACAATCAGTACGAGAGGGAGAAATTGGCGTATGCAAAAAAGCTAGCGAAAGAGGAGGCGCAACGACACAAGGAGCAAGCTAGGCTCATCAAGGAGCAAGAGAAAACGGAAAGGCAGGAGGCAGTGAGGCGAGAACGGGAGATTCGAAATCAACAGCTGCTCGAGTTGGTTACGAAGCTCGAAAAAGGCTCAGCCTATCCTCTTCACAGTGAGACCACGCTAGAAATCCAACCACCACCTACCACCACCATCACGACCACTACCACTACCACCACGATCATTCACCCAAGTTGCTCAAAACAATTGTTTACGAACGTCCTCCTCGAACGAAGGACGGGCCACCGTCGTCGAAAAGAGCGACGGGTATCACTCGCACGCGTACCACCACGTAATCACGTACCGCCGATTAACACGATCGATTATTGGGCATCCCTAAACCTACAAACGCAGGGTCGAAAGCGGCTAGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAACGCGGTAAGAGCAAGAGCGACGTGGCGCGCGAGCTGGGTCTGGCTAGCAGCACGGTGGCCACCATTTGGAAGAATCGGGAAAGCATCGCGGAGAGCTGGAGGAACCGCGACATGATGCAGCACTCTGATGTCGAGGACTCGGTCGCAAAAAAGTCCGGCCTGTCCTCATCATCGTCGAATTTGGCGTCCGTCACGTCGTTGGTGACGAACAATACGGTTTTAAACACCGTCAACACCACCAACAGTAGCACCACCGGCACCACGTTGCCCACCGCCATCGTGGTGGCACCGCCACAGGTGCAGGTGGTGCCGCCGCCACCACCACCGCCTCTCCCATTGCCGACCACCTCCGCCACGGTCGTCCCGTCGACGTCGCAACCGACGCAGCTCTCCACACCGACAATCTCCAGCACCATGTCCACAGGCACCACCACCACCACCAACGCCAGCATGGACAATACTCAGCAGGCCCAGACCCAGACGCAAAGTCAGGAGCTTCTGGAGGTAAGATGTCGTATGACGCCTCCCGACCCCTCACCGAAATACCCTCAGATAACTCGAAAAAATCGAGTTACCAACCCAAAAATTCTCTCCGCCCTCGATCATCCCTTTCAGGGGAACCTTCCATCGCGAGTCGCGTCCTCGAGGTTTTTGCTCATATTCAGATGGAATTCACGATGGAATTGTGGTTGGTGA
Protein Sequence: MPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSTTPSMTGSSLPVSTQAPVTSSHHSTSTSSTPNSQTNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPPVPALSAHQTNTTTSSLMMEPRKYNRTGTESNDYRESVDRVEVIKLPAHSTNGSALPAPSSYTTTTNASNSNDSDAPLNLSLKPSTTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHATATGQTDDKNQRSLQEKMKNKVLEVSGEESNMDVTSESGSNTDVVTDTDDDNADGVPSAKRRKVKPSERDLQVPLERGWKRETVIKGLGKSGVIKGDVSYYSPCGKTFRSSPDLAKFLEQQNPPDLTTANFSFSSRPLVGEFLQPTMGLAEAEFVRLGAQEVARRLEELRAAGGFRDVRTNNQYEREKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRREREIRNQQLLELVTKLEKGSAYPLHSETTLEIQPPPTTTITTTTTTTTIIHPSCSKQLFTNVLLERRTGHRRRKERRVSLARVPPRNHVPPINTIDYWASLNLQTQGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDMMQHSDVEDSVAKKSGLSSSSSNLASVTSLVTNNTVLNTVNTTNSSTTGTTLPTAIVVAPPQVQVVPPPPPPPLPLPTTSATVVPSTSQPTQLSTPTISSTMSTGTTTTTNASMDNTQQAQTQTQSQELLEVRCRMTPPDPSPKYPQITRKNRVTNPKILSALDHPFQGNLPSRVASSRFLLIFRWNSRWNCGW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00226594;
90% Identity: iTF_01419640;
80% Identity: -