Basic Information

Insect: Bombus consobrinus
Gene Symbol: Hr39
Assembly: GCA_014737455.1
Location: JACXIU010000009.1:2197295-2226783[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2 1.6e+04 -6.5 6.4 120 141 49 70 23 106 0.48

2 5 1.9 1.6e+04 -5.2 8.6 81 163 318 398 276 441 0.46

3 5 2 1.6e+04 -12.1 18.2 44 146 393 509 366 539 0.53

4 5 1.1e-07 0.00088 18.7 0.1 1 19 606 624 606 629 0.95

5 5 1.9e-71 1.5e-67 228.7 0.2 89 408 665 983 632 983 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2	1.6e+04	-6.5	6.4	120	141	49	70	23	106	0.48
2	5	1.9	1.6e+04	-5.2	8.6	81	163	318	398	276	441	0.46
3	5	2	1.6e+04	-12.1	18.2	44	146	393	509	366	539	0.53
4	5	1.1e-07	0.00088	18.7	0.1	1	19	606	624	606	629	0.95
5	5	1.9e-71	1.5e-67	228.7	0.2	89	408	665	983	632	983	0.75

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCTGGACCGGGCCCAGGGCCGGGTCCTGGTTGGTGGCCAACCTCACAGTCCTGGAAAACGAACTCCTGCACCGCTGCCTCCCCGTCCACTTGTTCAACCATTTCAGACAACTCCGCCTCCGTCTCTGCCTCTTGCACCACCTCTACGTCCTCCCTGGCGACCACCACATCGGCCACTTCATCGACCAGCTGCTGTTCCTCCACCCCTGCCGGTGGACCGTCTTGCACGATCACCGCGGCCCGCTCCTCCGAAACGGGAAAGAACGTCTCTGTCACGACGATCAATGTACCCCCTAATCAGGACATGCACGATGGCAAGGGTATATGCAAGTATCTTGGCGGCCAGAACGGCGTGACAGTATCGGTGGTGTCAAGCTGTGGCTCCGTACTGGGATGTGGAAACGCGAACGTCGTGTCTACCACGGGGATAGGCAGTAGCACCGGCACACAGAGTATTGGCATCGGAGTGAACATCCTTGACCAGAGCACGGCCGATGATGACGCGGATGATAGCGACGTTGAGATAAGCAAAATCGACTTCCGAGGGGTGAATTTGCGTACGAAGAAGAAACGAGACGTGTCTGGTAGCCAGAGTCAAAGCGGGGAGAAAATCGGCGATGGTGAGGTCGAGGATGGGAACGGTTGTTACGATGGAAGCGACGCGTCTCAGCAACAACCGGAGAGGCCCATGTCGTGGGAGGGAGAACTATCCGATCAAGAAATGTCTTCCAATACGATTACAAATCAAGATACACACGAGGACACGTCAATGGAGGGTGTTCAAGTATGCGGCACCAGTCCCGGGCCAATGGAACAAAAATTTCCCATAAAGCCAGAGCCAGATTTTCAGTCCAACTCAGGTTTCACGTTTGGCTCTTTTCACGACGCCGGATTACCTCTGAATCACGGCCAGCAGATACAACAACAGCAACAACAGCGCAACATTGAGAACCTTGAACAGACACAACAAAACGATTTGCCTCTTCTCGTAGGAAAATTACTCGGTGGTTACAATAGTTCGACTCCGAATCACAGTCCAGTGTTGAATCCCAGACACCATCTAACAAAGCATAGCCACACGAGATCGCAGGTGCCGTCACCGGACTCGGCCATTCATTCCGCGTACAGCGTATTCAGCTCCCCGACGCAAAGTCCTCACGCGACTCGCCACTCCCCCCTGGGCGCGGCAAGTCCAGTTCCATCTTCGTCGCTATCCTTGTCGCGACACAGTTTCAACAATTCCACTTCCTCGTTGTCGCTCTCGTTGTCACACTCCCTCTCGAGAAACAATTCGGACGCCTCGAGCAGCTGCTACAGCTACGGCTCTCTCAGCCCACCCACACACTCGCCCGTCCAGCAACCGAGACATCCGCAGCATCACCAGCATCAAGTTGCTCAAGGAAGCCCGCTTCATCTGCCAGCAACCGCTTCTCCCGCCATTACTCATCACTACGCTTCCTCCGCACCGGGTTCCGAGCTATCTCCAGAAGGACACGCCGCTACAGACGATCAGGAAGACTGTAGAATACCCTCGGCACCGTCCGGTATATCCACAAGGCAGCAACTAATTAATACCCCGTGTCCAATTTGCGGGGATAAGATCAGCGGTTTTCATTATGGAATATTCTCGTGCGAGTCGTGCAAGGGATTTTTCAAACGCACCGTCCAGAATCGAAAGAATTACGTGTGCCTTAGAGGCGCGGGCTGTCCAGTCACCGTTGTTACCAGGAAAAAATGCCCCGCCTGCAGATTCGAGAAGTGCCTCAATATGGGTATGAAGCTGGAGGCGATCAGGGAGGATCGCACCAGAGGTGGCAGAAGTACCTATCAGTGTACATATACTTTTCCGCCAAATTTTGTCGGTAGTCCTGCGAGTAACATGTCCAGCGACAAATTAGCCACCGGAGGAAATTGTAGTCCAGCTCCAGCTGGTAACGAACATCACTATCCGGCAAGGCACCATTCGAATCACTCGCATAAGATGCAAGTGGTACCGCAACTTCTACAGGATATCATGGACGTAGAACACTTGTGGCATTACAATGACAACGATCGTATGACCGGGATTCAAAACGCAGGAACGAATTTCGCTAGAAACAACGATTCAATGTTATCGAGTGTTAGAAGCAACGGAGGATCTGGAATAGAGAACGACGCGGGTTCAGGTATCGAGTGTTCCTCCAACAGAACTACGGGAAATGGTAATCCTAGTAATAGAAGAGATAACAGATCATGCTCCAATGTTTCCAACGTTGGTAACGAACAACACGCTGCACCCGTTGCTAACAGTTCTCAAATCAACAATACGAATTGCAATCCAACTCAACATCCTGATTTTCTGTCGAACCTCTGCAATATCGCTGATCATCGACTCTACAAAATAGTGAAGTGGTGCAAGAGTTTGCCGTTATTTAAAAACATTTCGATCGATGATCAGATCTGTCTGTTGATTAATTCTTGGTGCGAGCTACTGCTCTTCTCGTGCTGCTTTCGCAGTATGAGCACTCCCGGTGAAATTAGAGTGTCTCTCGGTAAGTCGATTACACTGGAACAAGCTAGGCAGCTTGGCTTAGCGACCTGCATCGAGAGGATGCTTGCATTTACTAACAATTTGAGAAGGCTCCGAGTAGATCAGTACGAATACGTGGCGATGAAGGTAATAGTACTGTTGACCTCTGATACAAGCGAACTGAAAGAACCTGAAAAAGTTAGAGCATCTCAGGAAAAGGCTTTGCAAGCGTTGCAACAATATACTATCGCAAGGTACCCAGAAATGCCTGCTAAGTTTGGTGAATTATTATTGAGAATTCCAGATTTACAAAGAACATGCCAAGCAGGAAAGGAATTGCTAAGTGCTAAACGCGCTGAAGGAGAAGGCAGCTCGTTTAATCTGTTGATGGAATTGTTGAGAGGAGATCACTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPGWWPTSQSWKTNSCTAASPSTCSTISDNSASVSASCTTSTSSLATTTSATSSTSCCSSTPAGGPSCTITAARSSETGKNVSVTTINVPPNQDMHDGKGICKYLGGQNGVTVSVVSSCGSVLGCGNANVVSTTGIGSSTGTQSIGIGVNILDQSTADDDADDSDVEISKIDFRGVNLRTKKKRDVSGSQSQSGEKIGDGEVEDGNGCYDGSDASQQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGTSPGPMEQKFPIKPEPDFQSNSGFTFGSFHDAGLPLNHGQQIQQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHATRHSPLGAASPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASPAITHHYASSAPGSELSPEGHAATDDQEDCRIPSAPSGISTRQQLINTPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVVTRKKCPACRFEKCLNMGMKLEAIREDRTRGGRSTYQCTYTFPPNFVGSPASNMSSDKLATGGNCSPAPAGNEHHYPARHHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRMTGIQNAGTNFARNNDSMLSSVRSNGGSGIENDAGSGIECSSNRTTGNGNPSNRRDNRSCSNVSNVGNEQHAAPVANSSQINNTNCNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_00228733;
80% Identity: iTF_00217130;