Basic Information

Insect: Bombus confusus
Gene Symbol: Hr39_2
Assembly: GCA_014737475.1
Location: JACXIV010000158.1:101764-131518[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.97 7.5e+03 -4.3 4.4 120 140 49 69 22 111 0.47

2 5 1.5 1.2e+04 -4.9 8.8 79 163 316 401 278 430 0.46

3 5 2 1.6e+04 -16.5 22.2 70 129 421 500 317 543 0.52

4 5 1.7e-08 0.00013 21.3 0.0 1 24 609 632 609 673 0.85

5 5 3.2e-71 2.5e-67 227.9 0.1 97 408 676 986 641 986 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.97	7.5e+03	-4.3	4.4	120	140	49	69	22	111	0.47
2	5	1.5	1.2e+04	-4.9	8.8	79	163	316	401	278	430	0.46
3	5	2	1.6e+04	-16.5	22.2	70	129	421	500	317	543	0.52
4	5	1.7e-08	0.00013	21.3	0.0	1	24	609	632	609	673	0.85
5	5	3.2e-71	2.5e-67	227.9	0.1	97	408	676	986	641	986	0.80

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCTGGACCGGGCCCAGGGCCGGGTCCTGGCTGGTGGCCAACCTCACAGTCCTGGAAGACGAACTCCTGCACCGCTGCCGCCTCGTCCACTGGTTCAACCGTTGCAGACAACTCCGCCTCCGTCTCTGCCTCTTGCACCACGTCTACGTCCTCCCTGGCGACCACCACATCGGCCACTTCATCGACCAGCTGCTGTTCCTCCACTCCTGCCGGTGGACCGTCTTGCACGATCACCGCGGCCCGCTGCTCCGAAACGGCGAAGAACGTCTCTGTCACGACGATCAACGTACCCCCTAATCAGGACATGCACGATGGCAAGGGTATATGCAAGTATCTTGCCGGCCAGAATGGCGTGACGGTATCGGTAGTGTCGAGCTGTGGCTCCGTACTGGGATGTGGAAACGCGAATGTCGTGTCTACTACGGGGATCGGCGGCAGCACCGGCACGCAGAGTATTGGCATCGGAGTGAACATCCTTGACCAGAGCGCAGCGGATGATGACGCGGAGGATAGCGACGTTGAGATAAGCAAAATCGACTTCCGAGGGGTGAATTTGCGTACGAAGAAGAAGCGAGACGTGTCTGGTAGTCACAGTCAAAGCGGGGAGAAAATCGGCGATGGAGAGGTCGAGGATGGGAACGGTTGTTACGATGGAAACGATGCGTCTCGGCAACAACCGGAGAGGCCCATGTCATGGGAGGGAGAACTATCCGATCAAGAAATGTCTTCCAATACGATTACAAATCAAGATACACACGAGGACACGTCAATGGAGGGTGTTCAAGTATGTGGCGCGAGTCCCGGGCCAATGGAGCAAAAATTTCCCATAAAACCAGAGCCAGATTTTCAGTCCAACCCAGGATTCACGTTTGGCTCTTTCCACGACACCGGATTACCTCTGAATCACGGCCAGCAAATACAACAACAGCAACAACAGCAACAACAGCGCAACATTGAGAATCTTGAACAGACACAACAAAACGATTTGCCTCTTCTCGTAGGAAAATTACTTGGCGGTTACAATAGTTCGACTCCAAATCACAGTCCAGTGTTGAATCCTAGACACCATCTAACAAAGCATAGCCACACGAGATCGCAGGTGCCGTCACCGGACTCGGCCATTCATTCCGCATACAGCGTATTCAGCTCCCCGACGCAGAGTCCTCACGCAGCCCGCCACTCCGCCCTGGGCGCGGCAAGTCCAGTTCCATCTTCGTCGCTATCCTTGTCGCGACACAGTTTCAACAATTCCACATCCTCGTTGTCGCTCTCGTTGTCACACTCCCTCTCGAGAAACAATTCGGACGCCTCGAGCAGCTGCTACAGTTACGGCTCTCTCAGCCCACCCACGCACTCGCCCGTCCAGCAACCGAGACATCCGCAGCATCACCAGCATCAAGTTGCTCAAGGAAGTCCACTTCATCTGCCAGCAACCGCTTCTCCCGCCATTACTCATCACTACGCTTCGTCTGCACCGGGTTCTGAGCTATCTCCAGAAGGACACGCTGCAACAGACGATCAGGAAGACTGTAGAATACCCTCGGCACCGTCTGGTATATCCACAAGGCAGCAACTAATTAACAGCCCGTGTCCAATTTGCGGGGATAAGATCAGTGGTTTTCATTATGGGATATTCTCGTGCGAGTCGTGCAAGGGATTTTTCAAACGCACCGTCCAGAATCGAAAGAATTATGTGTGCCTTAGAGGCGCGGTCTGTCCAGTCACCGTTGCTACCAGGAAAAAATGCCCCGCCTGCAGATTCGACAAGTGCCTCAATATGGGTATGAAGCTCGAGGCGATTAGGGAGGATCGCACCAGGGGTGGCAGAAGTACCTATCAGTGTACATATACTCTTCCAGCAAGTCTTGTCGGTAGTCCAGCGAGTAACATGTCCAGCGACAAATTAGCTAGCGGAGGAAATTGTAGTCCAGCTCCAGCTGGTAACGAACATCACTATCCGGCAAGGCACCATTCGAATCACTCCCATAAGATACAAGTGGTACCGCAACTTCTACAGGATATCATGGATGTAGAGCACTTGTGGCATTACAATGATAACGATCGTATGACTGGGATTCAAAACGCAGCAACGAATCCTACTAGAAACAACGATTCAATGTTATTGAGTGTTAGAAGCAACGGAGGATCTGGAATAGAGAACGACACAGGTTCAGGTATTGACTGTTCCTCCAATGGAACTACAGGAAATGGTAATTCTAGTAATAGAAGAGATACCAGATCATGCTCCAATGTTTCTAACGTTGGTAACGAACAACATACTGCACCCGTTGGTAACAGCTCTCAAATCAACAATGCTAATGGTAATCCAACTCAACATCCTGATTTTCTGTCGAACCTCTGCAATATTGCTGATCATCGACTCTACAAAATAGTGAAATGGTGCAAGAGTTTGCCGCTATTTAAAAACATTTCGATCGATGATCAGATCTGTCTGTTGATTAATTCTTGGTGCGAGCTACTGCTCTTTTCATGCTGCTTTCGCAGTATGAGCACTCCCGGTGAAATTAGAGTGTCTCTCGGTAAGTCGATTACACTGGAACAAGCTAGGCAGCTTGGCTTAGCGACCTGCATCGAGAGGATGCTTGCATTTACTAACAATTTGAGAAGGCTCCGAGTAGATCAGTACGAATACGTGGCGATGAAGGTAATAGTACTGTTGACCTCTGATACGAGTGAACTGAAAGAACCTGAAAAAGTTAGAGCATCTCAGGAAAAGGCTTTACAAGCATTGCAACAATATACTATCGCAAGGTACCCAGAAATGCCTGCTAAGTTTGGTGAATTATTATTGAGAATTCCAGATTTACAAAGAACATGCCAAGCAGGAAAGGAATTATTAAGTGCTAAACGTGCTGAAGGAGAAGGCAGCTCGTTTAATCTGTTGATGGAATTGTTGAGAGGAGATCACTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPGWWPTSQSWKTNSCTAAASSTGSTVADNSASVSASCTTSTSSLATTTSATSSTSCCSSTPAGGPSCTITAARCSETAKNVSVTTINVPPNQDMHDGKGICKYLAGQNGVTVSVVSSCGSVLGCGNANVVSTTGIGGSTGTQSIGIGVNILDQSAADDDAEDSDVEISKIDFRGVNLRTKKKRDVSGSHSQSGEKIGDGEVEDGNGCYDGNDASRQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGASPGPMEQKFPIKPEPDFQSNPGFTFGSFHDTGLPLNHGQQIQQQQQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAASPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASPAITHHYASSAPGSELSPEGHAATDDQEDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAVCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPASLVGSPASNMSSDKLASGGNCSPAPAGNEHHYPARHHSNHSHKIQVVPQLLQDIMDVEHLWHYNDNDRMTGIQNAATNPTRNNDSMLLSVRSNGGSGIENDTGSGIDCSSNGTTGNGNSSNRRDTRSCSNVSNVGNEQHTAPVGNSSQINNANGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_00228733;
80% Identity: iTF_00216422;