Basic Information

Gene Symbol
-
Assembly
None
Location
JAPVRH010004869.1:11669-16003[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00077 0.06 14.1 0.3 1 23 186 208 186 208 0.94
2 15 0.0036 0.27 12.0 2.6 3 23 216 236 214 236 0.95
3 15 0.0013 0.099 13.4 0.1 1 23 380 402 380 402 0.97
4 15 0.0009 0.069 13.9 0.5 1 23 408 430 408 430 0.98
5 15 7.3e-05 0.0056 17.4 2.3 1 23 462 484 462 484 0.97
6 15 0.0094 0.72 10.7 0.3 1 23 500 522 500 522 0.94
7 15 0.0072 0.56 11.1 0.4 1 23 528 551 528 551 0.98
8 15 0.37 28 5.7 0.4 5 19 562 576 559 577 0.91
9 15 0.00018 0.014 16.1 5.6 1 23 586 608 586 608 0.97
10 15 0.076 5.8 7.9 0.4 3 23 615 635 613 635 0.96
11 15 1e-05 0.0008 20.0 1.0 1 23 643 665 643 665 0.98
12 15 0.0052 0.4 11.5 0.2 3 23 673 693 671 693 0.97
13 15 0.00016 0.013 16.2 0.8 1 23 699 721 699 722 0.95
14 15 0.073 5.6 7.9 0.1 1 23 732 754 732 754 0.97
15 15 0.018 1.4 9.8 0.0 1 20 1276 1295 1276 1298 0.93

Sequence Information

Coding Sequence
ATGGACAGGCaaacttttgaaatacaaTGGATACAAGAAGATCAGGATGATCTTAAAACAGCAAATGGTCAACTGATTGTAAAATCACAATTACCGTCTGAAGATGAACTTCTGGTCAACGATGCAGCTGATGCTGGTAGAGAGGAATACCAATTGGTCACTGGTAATGATGAAGATGGGAATGTACCAAATGAAGTTAACATTGATCAAATAGCTGcagaaaacttaatatttatggCGCATGATGGTCAAATGGTAACGGAGATAATTGATGCCACTAGGGCTAATAATACTACCGTCGTCGTCGCTACTTCCGATGAGATTGACTGTACAGAAGTATTGCAACAAACTGGAAATGGTTTTATTGATAGTTTTGTCGATACTACACCACAAATGGTAACAGAAGAGGTGATAACGGACGACTGGGTACAGCATCAAGGCGAAGAGCGTGTGGAAATATCAGCCGATCAAATAATTTGTTCTGGTTCTCAAGTATTGCTGGATATGGAAGTGCCGTTGCCTACTGTTCAGGATGAGTATACTGCTCTACGTCCATTCCCATGCGATTTTTGCAGTCGCCGTTTCCGTAAAAAGGCAGGTTTGATGAATCATATAGGTGCACATCAGAACGATAGGCCACATTTGTGTAAACTATGTGACTCACGGTTTTTCCGTCGTTCTGATCTAATAAATCACCTTAAAGCACATGCTGATGCCCCCGATCCTGAGTTAGATACAGAATTTATGAACTTCGACGAACGAGAACACCAGCAGTTGCAATTGCGACAACCTAATGATCATTACTATGAGCAAGATTGGACCACACACATAAATTCCTTGCAACGTGGCGAAAAATCTAGTCGGAAACCGCACAATGTTAGCGGGAACAGTTCATCTACCTCAACATCCACGACAATAGGTCGTGGTCGTATTAGTCGAATTAAACCAAAAGAAGAAAGTTATGTTTTAAATGAGTCACATGAAAATGAAACAGCTGGGTTGGCGAATTTAGAGAACCCGTCTAGTGCTTTTGAAGACTGCCAACAACTACAGGCCTCCACTGCGGTTgtgaaatttacacaaaaccAATCACCAGCCCATCAAAAAAACTTCCCCGTTATCGATGAGAGTAAACCATTTGTTTGTCAGCAGTGCGGATTGGCCTTTGCACGTGAGAAAGCAATGCTAGCCCATACAAAGAATCATAGTGAAGATCAACCGCATGAgtgcaacaaatgcaatgaGATGTTCTGGGATGCAGACGGTCTCCAAGAGCATCTGAAAACTCATCAATTTGAAGATAGTAACTCGGAATACGACCCCGACGAAGCAGAAGCTGAAGAAACCCAAAGCGAATCTGAATCGGAGCGTTTGTTTGGGGAGTTTTACTGCAGCGAATGTGGTATGTCATTTCATAGAGAAGATTTGCTGCGCAGACACtccaaaatacacacaaaaactATCGCTGAATGTGATATCGATAATGTTAAGGATCGACATTGTTGCAACACATGTGGCGAAACGTTTGCCGAGGCCTTAGATTTACTAGCGCACGCTGAAATACATGCACGTTATCCACcatataaGTGTGTTCTTTGTGGCGAGACATTTTTTGAGGAGCTAACGATTAAACGTCATCTGCGGTCAGTGCATCCACACGACATGACGCCCAATTCATGTATACTCTGTGGCAAACAATGCCGGGATCGTAAAGCTTTAATAAAGCATGCCTGGGATCATTCACGAGAAAAATGTCACTCGTGCTCAAAATGTGGCAAGAACTTTCATAACAAGGCACGTCTGAAACGGCATATGGCGTCTCATCGTGATAAGTCGGTAATCTGCGATGTGTGTCAAGAAGAATTTCCAGATGGTCGCACTCTCTCCAACCATCGACACTCGCATACTAATGCTTCAGGTAAACTGTTTCCCTGCCATGAATGTGGCAAAACGTTCGGTTCGCGCAGTTCTCAGCAAATACATGTGCGCATACACACCGGTGAGAGGCCTTATGGTTGCCGCTTCTGTTGGAAGGCGTTTGCTGATGGTGGTACATTACGTAAACACGAACGTATTCACACGGGCGAAAAACCTTACGCTTGCTCGGTATGCTCACGTGCATTCAACCAACGCGTTGTTTTGCGCGAACATATACGATCTCATCATTCTGGATTGGATGCAAAACGTAACACATACTACTGCAACGTATGCTCTATGGAAATGTCGTCATCTGGAGATCTTGTGCAACATCTAATACAGCACAGTGATATGAACACTGCCATGCAGAGGCAACCAATTACTGGCCCACGTAAGTATAAAAGGCGGCGAAAGTTGAAACCACATGAAATCGCACGTCTGCGGAGAGAAGGCCAGCAAAATTGCAATGGAAGTGATATCGAAATATCAGACTTCGAATTGGATAATGTAGATGACCTCTTAGGCATTACAGAACCTATTCCGGTCTCCAAATCTTCAAAATCCAAACGTAGGAAAGTTAAAGACAGCATCAATAACAATTCCTTGATGAAGGAAGGAGTAGATGGGGTTATACTACCAGATAATGATCTACTTGTCGTACAGTCTAGGAAGCCGCGTTATAAATCGTCGGGTAGTAACTCGGATACTTTCTGGCAAACAAAGCTCAATACCAGTTCGTTACTATcgaatttagaaaatacttTGCAAAGCATCGACACACTTGTAGTGGGCTCTTCGGTTGGCGGCGCCACACATTTAGATGCGGAAGAACGCAAATCGAGGAACAAATCGGGAAGTGAGATTAGTACTGGTGGCGGTTCACAACGCACCCAGGAGGTGCAGATTAACAAGAATTATAACGTGAATAAAGCGCGAAAAAGGATCGAAAAAGCATCGACAACGAAAGCAACCCGTCCGCGCATGATCCATACGGAAAAATTATCATCCACCTACAATGACTATGGGCGAAAACGTTCTAAAACAGTCGTAACACATAGAGAGCAAAACGGTCTAGATTTATTGCGTCCTACCGGTCGATCGATGGTGGATGACTATGAAATTCTTTCACCTGCCACTGAATTGCCCAAACAGATTAGTTCAAGCCCACCAGGAATTAAAGAAGAGATGGGGCAAAATAATCACAATGATGTACATGTTTCAAATTCTTCAGGGAATGTAGATCTCTATGACACACAGTTCCTCAATGGAGCTTCGACGCTACGCAAGGAAGCCTATGAAAAATTCAACCCAAGTATAGTTAACGATCTCGAAGAGATTTTGCGTTCTCCCATCAAATGTGATCGTGCAGAGCGTCATCGCTTTATAAGTGAGTCTTCCACACCATTTCTCGAAGATGAGCAACataatatgataaaaatcGAACCAACTTCACCAGATTTGCGTGAGATCGTTGTTGGTGTCAGCGGCTCTGCTGGTATGAGTGCAAGTGgtggcagcggcagcagcaatgAACGTCGTTACGCACGCACTGCACGCAATTGCACTGGCgctataaatagaaaatatttagaatttgatTCGGATCTGCAAACTAATGGTTCAACACGTTATCAAAAGCGTAGTGCAACAACTTGCAATGGTAACAGttcaaaaagcaaacaagCCAAGAACAATAGACGTGAGAAAAAAGAAGGTTCCACAATAAACCAAAGAACTACCACATATTCTTCAACTTACGGTGGCTCACTGAGCACCACTAACGATTCGTCCTTCTCTTCACTCTCGCCAACGGACGGCGCTACTACGGTGTCAGCAGTATCAGCAGTATCAGCAGTATCAGCCACGTCGCCGACAGCACCAACCCAACCGGATCGCAAAGTGCGGTACTTCGAGTGTGAGATGTGCTCGGCTGTATTTCCAGATCGAGCCCAGCTGCTGGATCACGtgcctatacatatataa
Protein Sequence
MDRQTFEIQWIQEDQDDLKTANGQLIVKSQLPSEDELLVNDAADAGREEYQLVTGNDEDGNVPNEVNIDQIAAENLIFMAHDGQMVTEIIDATRANNTTVVVATSDEIDCTEVLQQTGNGFIDSFVDTTPQMVTEEVITDDWVQHQGEERVEISADQIICSGSQVLLDMEVPLPTVQDEYTALRPFPCDFCSRRFRKKAGLMNHIGAHQNDRPHLCKLCDSRFFRRSDLINHLKAHADAPDPELDTEFMNFDEREHQQLQLRQPNDHYYEQDWTTHINSLQRGEKSSRKPHNVSGNSSSTSTSTTIGRGRISRIKPKEESYVLNESHENETAGLANLENPSSAFEDCQQLQASTAVVKFTQNQSPAHQKNFPVIDESKPFVCQQCGLAFAREKAMLAHTKNHSEDQPHECNKCNEMFWDADGLQEHLKTHQFEDSNSEYDPDEAEAEETQSESESERLFGEFYCSECGMSFHREDLLRRHSKIHTKTIAECDIDNVKDRHCCNTCGETFAEALDLLAHAEIHARYPPYKCVLCGETFFEELTIKRHLRSVHPHDMTPNSCILCGKQCRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVICDVCQEEFPDGRTLSNHRHSHTNASGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCSRAFNQRVVLREHIRSHHSGLDAKRNTYYCNVCSMEMSSSGDLVQHLIQHSDMNTAMQRQPITGPRKYKRRRKLKPHEIARLRREGQQNCNGSDIEISDFELDNVDDLLGITEPIPVSKSSKSKRRKVKDSINNNSLMKEGVDGVILPDNDLLVVQSRKPRYKSSGSNSDTFWQTKLNTSSLLSNLENTLQSIDTLVVGSSVGGATHLDAEERKSRNKSGSEISTGGGSQRTQEVQINKNYNVNKARKRIEKASTTKATRPRMIHTEKLSSTYNDYGRKRSKTVVTHREQNGLDLLRPTGRSMVDDYEILSPATELPKQISSSPPGIKEEMGQNNHNDVHVSNSSGNVDLYDTQFLNGASTLRKEAYEKFNPSIVNDLEEILRSPIKCDRAERHRFISESSTPFLEDEQHNMIKIEPTSPDLREIVVGVSGSAGMSASGGSGSSNERRYARTARNCTGAINRKYLEFDSDLQTNGSTRYQKRSATTCNGNSSKSKQAKNNRREKKEGSTINQRTTTYSSTYGGSLSTTNDSSFSSLSPTDGATTVSAVSAVSAVSATSPTAPTQPDRKVRYFECEMCSAVFPDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01563089;
90% Identity
iTF_00191510;
80% Identity
-