Adix013862.1
Basic Information
- Insect
- Atrophaneura dixoni
- Gene Symbol
- Mbd3
- Assembly
- GCA_018248015.1
- Location
- DWHX01004239.1:1-3661[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.4e-24 5.3e-21 75.6 0.1 11 72 1 57 1 61 0.95 2 2 0.00054 2 9.7 0.1 29 74 79 132 64 135 0.87
Sequence Information
- Coding Sequence
- TTACCAAAGGGTTGGCAAAGAGAAGAAATCCTCAGAAAAACGGGACTTTCTGCAGGCAAAGTCGATGTTTACTATTACAGcCCTACAGGTAAAAAGTTTCGCAGTAAACCCGAGCTAGTTCGATATCTGGGTGATAGTATGGACCTGTCATGTTTCGACTTTCAACAAggtcaaataaatacaatgctCCTGTGCAAGACCAAGAAAGCTCGAGCCCAGTTTGACTACAGAGGAGTGCGCTCTGATGCTTCACTGGTACCACCAATACGTCAGACCGcatcaatttttaaacagcCCGTAACAGTTTATAAAACGCAAGAGAGCAAAGTTAAAACGGATTTGAAACAAGGCACACAAGAGAAACCTAAGCAGTTATTTTGGGAGAAACGTCTCGagaatttAACTGCGTGTGATGCAAACGGTGTTATCGGAGTGACTACATTGCCGAAGTACATTAAACCATTGGGACCTTTCACAACTGATGCAACTACTATACAGTCACTGGCTACTGCTTTACATGTCTCATCACAACCTATTAcagGTCAAACTGGATCAAAGCAGACCATCATGGAGAATCCGGGCGTTTTTTTGAATCCTGAACAGCCACTGATTGCTGCAGTGACAATAACCAAAGACGACGTCAAACGTCAAGAGGAGAGAGTGAACCGCGCCCGACAGAGGCTGCGAGCTGCTTTGGTGGCGGCATAG
- Protein Sequence
- LPKGWQREEILRKTGLSAGKVDVYYYSPTGKKFRSKPELVRYLGDSMDLSCFDFQQGQINTMLLCKTKKARAQFDYRGVRSDASLVPPIRQTASIFKQPVTVYKTQESKVKTDLKQGTQEKPKQLFWEKRLENLTACDANGVIGVTTLPKYIKPLGPFTTDATTIQSLATALHVSSQPITGQTGSKQTIMENPGVFLNPEQPLIAAVTITKDDVKRQEERVNRARQRLRAALVAA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01090793;
- 90% Identity
- iTF_00000356;
- 80% Identity
- -