Acir013217.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Athalia circularis
Gene Symbol
KEAP1
Assembly
GCA_963978495.1
Location
OZ021699.1:32138461-32141853[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.9e-32 3.3e-29 101.7 0.3 4 109 89 192 86 193 0.95

Sequence Information

Coding Sequence
ATGTCACGGACTGTATACACATTGTTGTGCATGCTCGACGTTGACGATATCGGGATGGATGGAGAAGAAGATTATTCAGAAATGGAAGGAAACAAATGTAAcagttatttttcttcattctgtAAAAATGGTGGTGCTACAGCTGCCCCCTGCGAAGAAAAGGAATCTACTGTGACCCTTGGTAATGAAAAACATGGTGACCTTGGAGATATGACCTTTTGCATGGCTAATTATATAAAAGAAGCTATGAAAATGATGTTCATGATGCGAAGTCATCATATGCTTACCGACGTTATCCTGGAAGTTGGACAAGAATTATTCCATGCGCATAAAGTCATTTTGGCTGCAGCAAGTCCTTATTTCAAGGCAATGTTCACAGGAGGTCTCAAAGAATGTGAAATGACCAGAGTAAACCTACAAGGAGTTTGCCCAACAGCAATGGCTCGActtttgtattttatgtacacgGGCCAGATCAGAGTCACTGAGGTAACGGTGTGCTCTTTATTACCTGCAGCGACGATGTTCCAGGTCAGTAATGTCATAGATGCATGTTGCGTGTTCCTCGAGAGACAATTAGATCCAACGAATGCAATCGGTATCGCAAATTTTGCAGAACAGCATGGCTGCCACGATTTGCATCACAAAGCCAATCAATTCATCGTCCAACACTTCAACAGGATTTGTCAAGAAGAGGAATTCTTACAACTTACTGCTATTCAATTGATAAGCCTCATTCGAAAGGACGAGTTGAACGTTCAAGAAGAGCGAGAAGTATACAATGCCGTGTTGAAATGGGTAAAATATAACGAAGAATCACGTGGTGTCAAGATGGAACACATACTGCAGGCTGTTCGCTGTCAATACTTGACGCCAAGTTTTCTCCGGGAACAAATGAAGAATTGTGATGTTCTAAAGAAAGTGCCTGCCTGCCGCGAATATCTAgcacaaattttcaaagactTGACTTTACATAAAAAACCAGTTGTCAAAGAAAGAACGCCTAACACACCAAGAGTAATTTACATTGCGGGAGGATTTCTCAGGCACTCGTTAGACGTCCTAGAAGGATATAATGCCGATGACAAAATCTGGAGTCAACATGCAAAGTTAACGGTACCTCGTTCCGGGCTTGGGGGAGCATTTTTAAAAGGCATGTTCTATGCCGTTGGTGGTAGAAATAATTCCCCAGGAAGCAGATACGACAGTGACTGGGTGGACAGATATAATCCAGTTCTTGATCAATGGAGACCATGCAATCCCATGTCAGTACCAAGGAATAGGGTTGGAGTTGCAGTAATGGATGGCGTGTTGTACGCCGTAGGAGGCAGTGCTGGTGCAGAATACCATAACAGCGTTGAATGTTATGATACAGAACAAGATATTTGGACCAACGTTAAACCGATGCACACCAAACGATTAGGAGTCGGAGTTGCCGTCGTCAATCGATTGCTATATGCTATCGGAGGATTCGACGGCGAACACAGATTAAGTTCGGTTGAATGTTATCATCCGGAAAATGACGAGTGGACCATGGTATCTCCTATGCATTGTAGCCGCTCGGGGTCCGGGGTAGCAAGTCTCGGACAACACATTTATGTTGTGGGAGGTTATGATGGTACCCGTCAACTTAGTACAGTGGAACGTTACGACACAGAACGAGATACTTGGGAGTATGTCAGCGGAGTTTCAGTCGCACGAAGTGCTTTAAGTGTCACCGTACTTGATGGAAAACTTTATGCTATGGgAGGCTATGACGGACAGAACTTCTTAAGCATAGTAGAAATATACGATCCGGCTAAAGATCAATGGGAACAAGGGAAGCCAATGACGTCTGGTAGATCCGGTCATGCAAGTGCAGTTTCTTATCACCAGTGTCCATTGCATTGCGAACATTTAGAGCACCATATTGTCCCAGGCGGGACCCCAGCGAAACGCCCGTGTTAA
Protein Sequence
MSRTVYTLLCMLDVDDIGMDGEEDYSEMEGNKCNSYFSSFCKNGGATAAPCEEKESTVTLGNEKHGDLGDMTFCMANYIKEAMKMMFMMRSHHMLTDVILEVGQELFHAHKVILAAASPYFKAMFTGGLKECEMTRVNLQGVCPTAMARLLYFMYTGQIRVTEVTVCSLLPAATMFQVSNVIDACCVFLERQLDPTNAIGIANFAEQHGCHDLHHKANQFIVQHFNRICQEEEFLQLTAIQLISLIRKDELNVQEEREVYNAVLKWVKYNEESRGVKMEHILQAVRCQYLTPSFLREQMKNCDVLKKVPACREYLAQIFKDLTLHKKPVVKERTPNTPRVIYIAGGFLRHSLDVLEGYNADDKIWSQHAKLTVPRSGLGGAFLKGMFYAVGGRNNSPGSRYDSDWVDRYNPVLDQWRPCNPMSVPRNRVGVAVMDGVLYAVGGSAGAEYHNSVECYDTEQDIWTNVKPMHTKRLGVGVAVVNRLLYAIGGFDGEHRLSSVECYHPENDEWTMVSPMHCSRSGSGVASLGQHIYVVGGYDGTRQLSTVERYDTERDTWEYVSGVSVARSALSVTVLDGKLYAMGGYDGQNFLSIVEIYDPAKDQWEQGKPMTSGRSGHASAVSYHQCPLHCEHLEHHIVPGGTPAKRPC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01255773;
90% Identity
iTF_01414310; iTF_01411629; iTF_00175154; iTF_00175827; iTF_00060437; iTF_01413461; iTF_01412439; iTF_00939706; iTF_01303550; iTF_00938848; iTF_00719531; iTF_01200295; iTF_00718715; iTF_01049024; iTF_01048309;
80% Identity
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