Aver005904.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Asbolus verrucosus
Gene Symbol
RHOBTB1
Assembly
GCA_004193795.1
Location
QDEB01054458.1:2165-7695[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.3e-10 3.3e-08 33.4 0.1 3 45 256 299 254 316 0.80
2 3 1.2e-06 0.0003 20.6 0.0 47 103 358 413 346 416 0.82
3 3 3.4e-18 8.6e-16 57.8 0.1 5 107 440 541 437 544 0.93

Sequence Information

Coding Sequence
ATGGATAATGAACAACCCCACCAGGAACTCGTCAAGTGCGTGGTGGTGGGCGACACGGCGGTCGGCAAGACGCGTCTGATATGCGCCCGGGCGTGCAACAAGCAAGTCTCCCTGGCCCAGCTGCTCGCGACCCACGTCCCGACGGTGTGGGCCATCGACCAATACCGCATCTACAAAGACGTCCTCGAGCGCTCCTGGGAGGTGGTCGACAGCGTCAATGTCTCGCTGCGACTGTGGGACACCTTCGGCGACCACGAGAAGGACCGCCGCTTCGCCTACGGCCGCTCCGACGTCGTCCTCCTGTGCTTCAGTGTCAACAACCCGGTGTCTCTTCGCAACTGCCGCCTGATGTGGTTCCCGGAGATCCGCCGCTTCTGTCCAAGCACGCCGGTCCTCCTCGTCGGCTGCAAGAACGACCTGAGGTACATGTACAGGGACGAGGCCTATTTGAGCTACTTCCGGGACAGGAGCCCGTTCGTGAGGGCCACGCGCAAGAGCGACTTGGTGATGCCGGACGAGGCCAGGGACGTCGCCAGGGAGCTGGGGCTCTACTACTACGAAACCTCGGTACTTACCTATTACGGAGTTAACGAAGTGTTCGAGAACGCCATCAGGGCCGCGCTCATCGCCCGACGCCAGCAGCGCTTCTGGATGACCAACCTCAAGAAAGTGCAGCGTCCTCTGCTCCAGGCCCCTTTCAAGCCGCCGCCGCCCATGAAACCTGAAGTACTCGTAGTGGCGGGCTCTTACGCCGAACACATGCACCAGCTCTACTTGGACCGCGCTCACACCGACGTCGTTCTAGTCGTAGGCTCCGTGGGGTTCCCCGCTCACCGTTTCGTCTTGGCCGCGTGCAGTCGCGCTTTCTACCGGTTACTCGCAGCCGACCTCATGGCGAGGAGCACCAGCGACTCCAGCATGGTCAGTTCTTTGGGCGACTTCGCCGACGAAACCGAATGTCTGGTCAGAGCCGAGCAGAAGACGTGCAAACGACGCGCTAGCTGTCAAGCACTGCCTTCGGCCCGCGAACTCGACCACCCCGCTTTCCACTGCATCAGGAACGTGCAGCCCGAAGGACAGACTGTCGTCACTTTAAGCAAGTTAGTTACCCCGGGGGCGATGCACCAATGCCTCCAGTTCGCCTACACGGGGACCGTCGACCGTAGCGCCCTCAATCTCCAGGAAACTCGCGAAGCCGCCGAATTCTTGGAACTGCCGCAGCTTTTAATCCTTCTCACCAAACACCCATTCGTCGGCCCAGATCACCCAGACGAAACCTACGAAAACTTCCTGAAGAGGCGTTTACAAGACATCTGCCTCGACCAAGGCCTCTTCGCAGACGTCATTTTCGAGCTGGACGATGGTGCTTGCGCTGCACACAAGGCGATGCTCACAGCTCGATGTGACGTCATGAAGGCCATGTTCAGCGGGGATTTTCGCGAGAGCCAAGCCAAAGTGATCGAGTTTCCCGGAGTTAGGGAGTACACCTTCCACAAGCTGCTGTGCTTCTTGTACACCGACGAGATCCCGGCGGTGTCCGCGGTCCGCTGCGTCAACCTGCTGGAGTTGGCCAATCGACTTTGCCTGCCACGACTTGTCAATTTAGTGGAGAGGAGGGTGATCGAGGATCTGGAGTGCTTGCAGCCGTCGGAGGCCATCGAGCAGTGCTTGCGGCTGCTGGAGCCGGTCAAGTTGCACAACGGGCATCAGCTGGCCGACTGGTGCATGAACCACCTGTGCGTCAACTACAACAAGTTGTGCAGGATGTCTCCGCGCAGTCTTCGACTGCTGCATCCCGACAACCAAGCCTACTTGGTGGAGCACCGTTGGCCGCCCGTCTGGTATCTGAAAGATTACGACTACTACCAGAAGTGTTTGGCCGAGCGCGACAAAGAACTAAAGCCCACAATCAAAACCACATCGGGCTGTCTATGCTTCTCTCGCAAGTCAGAGTCTGATCCGGCCTTGTCCTCGAGTCAGCTCTGA
Protein Sequence
MDNEQPHQELVKCVVVGDTAVGKTRLICARACNKQVSLAQLLATHVPTVWAIDQYRIYKDVLERSWEVVDSVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSVNNPVSLRNCRLMWFPEIRRFCPSTPVLLVGCKNDLRYMYRDEAYLSYFRDRSPFVRATRKSDLVMPDEARDVARELGLYYYETSVLTYYGVNEVFENAIRAALIARRQQRFWMTNLKKVQRPLLQAPFKPPPPMKPEVLVVAGSYAEHMHQLYLDRAHTDVVLVVGSVGFPAHRFVLAACSRAFYRLLAADLMARSTSDSSMVSSLGDFADETECLVRAEQKTCKRRASCQALPSARELDHPAFHCIRNVQPEGQTVVTLSKLVTPGAMHQCLQFAYTGTVDRSALNLQETREAAEFLELPQLLILLTKHPFVGPDHPDETYENFLKRRLQDICLDQGLFADVIFELDDGACAAHKAMLTARCDVMKAMFSGDFRESQAKVIEFPGVREYTFHKLLCFLYTDEIPAVSAVRCVNLLELANRLCLPRLVNLVERRVIEDLECLQPSEAIEQCLRLLEPVKLHNGHQLADWCMNHLCVNYNKLCRMSPRSLRLLHPDNQAYLVEHRWPPVWYLKDYDYYQKCLAERDKELKPTIKTTSGCLCFSRKSESDPALSSSQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00392834;
90% Identity
iTF_01311637;
80% Identity
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