Apag004392.1
Basic Information
- Insect
- Arge pagana
- Gene Symbol
- Hr39
- Assembly
- GCA_963969455.1
- Location
- OZ018309.1:11083477-11088197[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4 1.8e+04 -13.5 18.3 126 163 256 292 103 425 0.61 2 4 4.9e-08 0.00021 20.8 0.0 1 21 494 514 494 519 0.92 3 4 0.026 1.1e+02 1.9 4.6 78 164 537 624 516 633 0.57 4 4 1.3e-69 5.9e-66 223.5 0.3 201 408 623 825 616 825 0.96
Sequence Information
- Coding Sequence
- ATGTCGGAACAGAACGGGCCCCCCGAGGGCCCAGGCTGGTGGCCTCCGGCCCAATCGTGGaagtcttcgtcttcgtcgaccTGTGCAAGACCGGAAGCCGGAAAAAACGTATCTGTGACGACTATCAACGTACCACCACCAGCCCACGAGATGCACGATGGTAAAAATGTTAAGTATTTGGGCGGTCGGAACGGCGTGACGGTGTCCGTTGTGTCCGGCTGCGCGACCGGAACCGAGCGACTGGACGACGGAGCTGATAGTGACGGCGAAGTGAGCAAGATCGACTTCCGGGGTGTTAATCTTCGcacgaagaagaaacgagacgcgCCCGAGGGCCAGGAGAGCGATGCTAGGAACGATGCGATGTTACAACAACCGGAGCGCCCCATGTCCTGGGAAGGGGAACTCTCCGACCAAGAAATGTCTTCCAATACGATAACGAGCCAAGACCACGAGGAAACCTCGATGGAAGGGGTTCAAGTGTGCAGCGCGTGCCCAGGACCAGTCCCAGCGTACCAAGAACCGAAATTTCCTATAAAACTGGAACCCGACTTTCGATCGAGTCCAGGACCACCTTTAGGACCACCCCGAGAAACATCGTTAACTGGCAATGCTCAGCAACATCAGCAGTACCAGCAGCGCCAACAACACAACCTCGACGGACTCGAGCAAAGCCAGCAAAGCGATTTACCACTTTTGGTTGGAAAATTACTGGGGGGATACAGCAATGCCACTCCTAATCACAGCCCAGTTCTGAATCCACGACATCATCTGACTAAACATAGCCATACGAGATCGCAGGTTCCATCCCCGGATTCAGCGATACATTCGGCGTACAGCGTATTCAGCTCCCCAACGCAGAGTCCGCACGCGGCTCGACACTCAGCGCTGGGAGCCGGCAGTCCTgtaccgtcgtcgtcgctgtcgcTTTCTCGTCACAGCTTCAACAATTCCACGTCTTCGCTCTCGTTGTCATTTTCCCACTCCCTGTCGCGAAACAATTCCGACGCGTCTAGTAGCTGCTACAGCTACGGCTCTCTCAGTCCACCGACGCATTCGCCTGTCCAGCAACCGAGGTATTCTCACTCCCACAGTTCGCACCCCCATCATCAAGTCGCAGCTCAAGGTAGTCCCCTCCATTTACCAGTATCGCATCACTATTCAGCTGCGAACTCTGAACTCTCGGAGGGATTGAGCGAGGATCAAGAGGATTGCAAAATAGCGCCAGCTACGTCCGGCATCTCGACGAGGCAACAGTTGATAAACAGTCCCTGTCCTATTTGCGGTGACAAAATCAGTGGATTCCATTACGGCATATTTTCTTGCGAATCGTGCAAAGGATTCTTCAAAAGAACTGTACAGAACCGAAAGAATTACGTTTGCCTGAGAGGAGCCGGATGTCCCGTTACAGTCGCTACCCGTAAAAAGTGCCCGGCTTGTCGCTTCGACAAGTGTCTTAATATGGGGATGAAATTGGAAGCGATACGGGAGGACAGAACCAGGGGTGGAAGGAGTACGTATCAGTGTAGTTATACGTTGCCGGCCAACCTTGTTGGCTGCACTTCCGGTAACTTGCCCAATGATAAGATGACCGGTGGAACCTGCAGTCCCGCGCCGCCTGGATACGAACATCATCATTCGACCAGGCATCACTCGAATCACTCGCATAAAATGCACGTCATACCGCAACTATTACAAGAGATCATGGACGTTGAGCATCTGTGGCATTacaacgacaacgatcgtCAAGCGAGCGCGcaaagtagtagtagtagcagcagcagtagtaaATCGGAACAACCCAGGCCAAATTCGGCAGGACCGATCAGTACCGATCAAGAGCCACATCCACCGACGAACGAAAACACGAATACTTCGCAGGAGCCAGACTTTTTGACGAATCTGTGTAACATAGCGGATCACAGGCTCTACAAAATCGTTAAGTGGTGCAAGAGTCTGCCTCTCtttaaaaacatttcgatCGACGATCAAATATGCCTTCTAATCAATTCCTGGTGcgagttgttgttgttttcttgTTGCTTCCGAAGTGTTAGTACACCGGGGGAGATTCGAGTGTCGTTTGGAAAGTCAATTACTCTCGAGCAAGCAAGACAGTTGGGTCTTGCCAGTTGCATCGAAAGAATGCTCGCTTTCACCAATAACCTCAGGCGTTTAAGAGTGGACCAATACGAGTACGTCGCCATGAAGGTTATCGTCCTGCTCACTTCCGACACGAGCGAACTCAAAGAACCGGAGAGAGTGAGATCATCTCAAGAGAAAGCACTGTCCGCGCTGCAGCAGTATACAATCGCCATGTATCCAGAAATGCCAGCCAAATTTGGAGAGCTACTCCTCAGAATCCCCGATTTGCAAAGGACGTGTCAAGTTGGAAAGGAGTTACTCAGCGCAAAACGAGCCGACGGAGAGGGTAGCTCGTTCAATTTATTGATGGAACTGCTCAGAGGGGACCACTGA
- Protein Sequence
- MSEQNGPPEGPGWWPPAQSWKSSSSSTCARPEAGKNVSVTTINVPPPAHEMHDGKNVKYLGGRNGVTVSVVSGCATGTERLDDGADSDGEVSKIDFRGVNLRTKKKRDAPEGQESDARNDAMLQQPERPMSWEGELSDQEMSSNTITSQDHEETSMEGVQVCSACPGPVPAYQEPKFPIKLEPDFRSSPGPPLGPPRETSLTGNAQQHQQYQQRQQHNLDGLEQSQQSDLPLLVGKLLGGYSNATPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSFSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRYSHSHSSHPHHQVAAQGSPLHLPVSHHYSAANSELSEGLSEDQEDCKIAPATSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTLPANLVGCTSGNLPNDKMTGGTCSPAPPGYEHHHSTRHHSNHSHKMHVIPQLLQEIMDVEHLWHYNDNDRQASAQSSSSSSSSSKSEQPRPNSAGPISTDQEPHPPTNENTNTSQEPDFLTNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVSTPGEIRVSFGKSITLEQARQLGLASCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPERVRSSQEKALSALQQYTIAMYPEMPAKFGELLLRIPDLQRTCQVGKELLSAKRADGEGSSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00174217;
- 90% Identity
- iTF_00938835;
- 80% Identity
- iTF_00159190; iTF_00159135;