Basic Information

Gene Symbol
-
Assembly
None
Location
CADEBC010000566.1:599672-605441[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.032 2 9.1 7.1 1 23 94 117 94 117 0.95
2 18 7.7e-05 0.0047 17.3 0.9 1 23 126 149 126 149 0.96
3 18 0.011 0.65 10.6 0.4 2 23 162 184 162 184 0.97
4 18 0.00045 0.028 14.9 1.1 1 23 193 216 193 216 0.97
5 18 0.005 0.31 11.6 3.1 1 23 228 251 228 251 0.96
6 18 9.2e-05 0.0057 17.1 0.9 2 23 283 305 282 305 0.97
7 18 0.001 0.065 13.8 1.2 2 23 315 337 314 337 0.96
8 18 0.1 6.2 7.5 1.7 3 20 343 360 341 362 0.90
9 18 0.00057 0.035 14.6 0.5 2 21 367 386 366 389 0.94
10 18 0.049 3 8.5 1.8 3 23 399 420 398 420 0.96
11 18 0.00066 0.041 14.4 4.6 1 23 425 448 425 448 0.94
12 18 0.00019 0.012 16.1 1.3 2 23 460 482 459 482 0.96
13 18 0.05 3.1 8.5 2.8 1 23 507 530 507 531 0.94
14 18 1.6 1e+02 3.7 0.1 2 23 537 558 536 558 0.86
15 18 0.025 1.5 9.4 2.0 2 23 564 585 563 585 0.97
16 18 0.74 45 4.8 0.5 2 23 592 615 591 615 0.90
17 18 0.012 0.73 10.4 0.2 1 23 651 673 651 673 0.97
18 18 0.24 15 6.3 2.8 1 23 679 702 679 702 0.97

Sequence Information

Coding Sequence
ATGAATATGAAACCTATAATAACAGAAACGATACCACCAGCTTTTGACCCAgaagttaatattaaagttgaaaaaattGAAGTTGAATTAGATTTTCAtgatTTTACTGATAATACAGGCCTTATGTTAGAAGGGCCGGAAAGTGAGGACAGCCAGGAGCCAGCTGTAAAAATTGAGAATCAAAACCATGAAGCTGTCTTGCTTACTTTTGAAAGTGTTATCAATCCCAAAAGAATGTTGCCTAAAAAGGAAGAGCTAGATATCGTACCTAAAGCAGAACACTTTTGCAAGATATGTCATCTGGTCTTCCAATCAACAAAAACACTAAGAATGCACCAGAAAAGAAAACACAAAGTGTTTAGAAAGTCATTCAAACATATTTGCGATAACTGCGGTATGTCCtatgaaacaaaaaacagtttAGTTGCACACATTAAACGTAAACATGGGCCAGATTCATTGCCTGATGATAAAGAAGAAAGAACTTGTGAGATATGTGCATTAGTGTTTAAAGGCATGGCCAGGTTACGTATGCACATGAGACGGAAGCATGGATCTTTCCAGGACTCCTTCCAACATGTATGTCAGGACTGTGGTCTGACTTATGATAAATATAGAAGTTTAATAGTTCATATACAACGTAAGCATTCAAATCAAACGACGCCAGAGATAAGTCAGTGGTACAATTGTATGTTTTGTCAGAAGATGTTCAATAAAAGAGAAACGTATGCAAGACATGTACAAAGGAAACATAGAATTGCTGACGATAATATAAAGCAAGAGAATCTTGGTGAAAACTTAGAAGGCGATCTCGAAAGTTGTAAAAATGAGCAAACAGGAGAAATCACTTGCAAGGAATGCCCTCTAGTGTTTTCTTCAATGAATTTCCTAAAACTACATATGCGAAGAAAACATAATGCTTTGAAAGAAAACTTCAGATTGAAATGTAGGATCTGTAACCTATCTTATGATAAGATTGAAAGTCTTAAACGACACGTGAGACGGAAACATGATAAAGGCTCACATTGCGAAGTGTGCAATAAACAATTTGATTCCAgagaaatgtatttaaatcacTCCCACACAAAAATTATCAAAGAGTGCACAATTTGTGGACTCATCTTTGCTTCTCAAGGGGGTTTAGCGAAACATTTAAGGTGTACACACAAAATAGACACACCAAAAACAGTCTTTTGTAACTTGTGCAATGAAGGGTTTCATGACAAACGGCAGTTGAAACCACATCTCATGAAAGTGCATTTAAAAGTTTCTTACACATGTATGCActgcaaaaaagtttttaaagcaaAGGAGAGTTATCGACGACATATCCTGTTCAAACACCCTACTCCGAACTATGTTAACACACAGCTGCAGAAATGTGAGCAATGTTCTGAAATGTTTAAGGATGAATTTGAACTTTGCAAACATATAAACATAGCCCACAGACATACAGATGAGAGTATGACAGAAGATGGCATGCATATAAAAAGGGAAGATGAAGATATCAAGAACAATTTCCAGTGCACCAAGTGTCCTGAGATTTATTTAACTTGGGATGAATTAAAACTGCACTATGAACAATGTCACCACAATATTCAACAAACTCAATGTCAAATTTGTGGAGAAATAATGCAAGGCAATGAACTGGAAAAGCATATAAAAGCATTACATACAAATAATGAGAAGCAGTGTAAATATTgtgaatttaaaacaaatattaaaataagtttaacacAGCACATGCTGAGACACAAAAATGCAGCAACGATACGTTGCGAGTACCCAGGTTGTCGGTATAAGACGTTTTATGAAGGTGCTATGGAGAAGCATAGACGAAAGCATCTTGATCAGGGAGTCAAACTCCAATGTGCGCAATGTCCTTTCCAaactatgaataaatatattttaaaatatcatgagGAAGCACATGAAACTGGTAAAAAGAGGTATTCATGTGACCAGTGTGATTATGCTACAATTCTGCCGGCAAATTTAGTGCAACATAAGTATAAACATTCTACAGAGAAGCGGTTCAAATGCGACGTGTGCTCCTTTGCAACTAAGTACAATACGTCATTAAGGTTTCATGTTAGGAAAAAGCACTGTGATCTCCCAACATTCAGctaa
Protein Sequence
MNMKPIITETIPPAFDPEVNIKVEKIEVELDFHDFTDNTGLMLEGPESEDSQEPAVKIENQNHEAVLLTFESVINPKRMLPKKEELDIVPKAEHFCKICHLVFQSTKTLRMHQKRKHKVFRKSFKHICDNCGMSYETKNSLVAHIKRKHGPDSLPDDKEERTCEICALVFKGMARLRMHMRRKHGSFQDSFQHVCQDCGLTYDKYRSLIVHIQRKHSNQTTPEISQWYNCMFCQKMFNKRETYARHVQRKHRIADDNIKQENLGENLEGDLESCKNEQTGEITCKECPLVFSSMNFLKLHMRRKHNALKENFRLKCRICNLSYDKIESLKRHVRRKHDKGSHCEVCNKQFDSREMYLNHSHTKIIKECTICGLIFASQGGLAKHLRCTHKIDTPKTVFCNLCNEGFHDKRQLKPHLMKVHLKVSYTCMHCKKVFKAKESYRRHILFKHPTPNYVNTQLQKCEQCSEMFKDEFELCKHINIAHRHTDESMTEDGMHIKREDEDIKNNFQCTKCPEIYLTWDELKLHYEQCHHNIQQTQCQICGEIMQGNELEKHIKALHTNNEKQCKYCEFKTNIKISLTQHMLRHKNAATIRCEYPGCRYKTFYEGAMEKHRRKHLDQGVKLQCAQCPFQTMNKYILKYHEEAHETGKKRYSCDQCDYATILPANLVQHKYKHSTEKRFKCDVCSFATKYNTSLRFHVRKKHCDLPTFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00405296;
90% Identity
iTF_01360976;
80% Identity
-