Basic Information

Insect: Apis mellifera
Gene Symbol: -
Assembly: GCA_003254395.2
Location: NC:8635100-8642941[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.43 26 4.6 5.6 2 23 241 263 240 263 0.96

2 21 0.012 0.74 9.5 2.0 1 23 313 335 313 335 0.97

3 21 0.22 14 5.6 1.4 1 23 384 406 384 406 0.98

4 21 0.022 1.4 8.7 0.2 1 20 461 480 461 482 0.93

5 21 2.8 1.7e+02 2.1 2.5 1 20 494 513 494 517 0.73

6 21 1.8e-05 0.0011 18.4 2.8 1 23 522 544 522 544 0.98

7 21 0.00018 0.011 15.3 0.3 1 23 592 614 592 614 0.97

8 21 0.00046 0.028 14.0 0.1 1 23 620 642 620 642 0.97

9 21 1.5e-06 9.1e-05 21.8 1.7 3 23 687 708 686 708 0.96

10 21 0.15 9.2 6.1 0.8 1 14 715 728 715 738 0.81

11 21 0.0028 0.17 11.6 0.9 2 23 747 768 746 769 0.94

12 21 0.00069 0.042 13.4 0.3 1 23 774 796 774 796 0.96

13 21 0.057 3.5 7.4 0.4 1 20 852 871 852 871 0.97

14 21 0.00026 0.016 14.8 0.1 1 23 890 912 890 912 0.98

15 21 0.00016 0.0099 15.4 0.5 1 23 926 948 926 948 0.97

16 21 5.3e-05 0.0032 17.0 2.7 3 23 965 986 964 986 0.95

17 21 0.005 0.3 10.7 1.5 2 23 1039 1061 1038 1061 0.93

18 21 0.023 1.4 8.6 1.4 3 23 1090 1111 1088 1111 0.92

19 21 0.0073 0.44 10.2 0.7 1 23 1120 1144 1120 1144 0.95

20 21 0.0043 0.26 11.0 1.4 1 23 1149 1172 1149 1172 0.97

21 21 0.082 5 6.9 0.7 2 23 1202 1224 1202 1224 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.43	26	4.6	5.6	2	23	241	263	240	263	0.96
2	21	0.012	0.74	9.5	2.0	1	23	313	335	313	335	0.97
3	21	0.22	14	5.6	1.4	1	23	384	406	384	406	0.98
4	21	0.022	1.4	8.7	0.2	1	20	461	480	461	482	0.93
5	21	2.8	1.7e+02	2.1	2.5	1	20	494	513	494	517	0.73
6	21	1.8e-05	0.0011	18.4	2.8	1	23	522	544	522	544	0.98
7	21	0.00018	0.011	15.3	0.3	1	23	592	614	592	614	0.97
8	21	0.00046	0.028	14.0	0.1	1	23	620	642	620	642	0.97
9	21	1.5e-06	9.1e-05	21.8	1.7	3	23	687	708	686	708	0.96
10	21	0.15	9.2	6.1	0.8	1	14	715	728	715	738	0.81
11	21	0.0028	0.17	11.6	0.9	2	23	747	768	746	769	0.94
12	21	0.00069	0.042	13.4	0.3	1	23	774	796	774	796	0.96
13	21	0.057	3.5	7.4	0.4	1	20	852	871	852	871	0.97
14	21	0.00026	0.016	14.8	0.1	1	23	890	912	890	912	0.98
15	21	0.00016	0.0099	15.4	0.5	1	23	926	948	926	948	0.97
16	21	5.3e-05	0.0032	17.0	2.7	3	23	965	986	964	986	0.95
17	21	0.005	0.3	10.7	1.5	2	23	1039	1061	1038	1061	0.93
18	21	0.023	1.4	8.6	1.4	3	23	1090	1111	1088	1111	0.92
19	21	0.0073	0.44	10.2	0.7	1	23	1120	1144	1120	1144	0.95
20	21	0.0043	0.26	11.0	1.4	1	23	1149	1172	1149	1172	0.97
21	21	0.082	5	6.9	0.7	2	23	1202	1224	1202	1224	0.94

Sequence Information

Coding Sequence: ATGGACGAAGTGATAGAGTTACAAAATATGGAAAACGTATGCAGGCTCTGCCTTTCCACCGATGAGCCAAAATCGTCGGTGTTCGAAACGGAAGACTCTCCGGTATCGTTGGCCAATAAAATACAAGCGTGTCTGTCGATTCAGATTTTAACGACGGACAAATTATCGACGAAAATATGCGCGCAATGTGTAAAAAATGTGAATCAGTGGCATAATTATAAGGAAGTATGTCTACGTTCCCAAGATAAATTGCAGCAATGGTTAGAACAGAATTTACAATCAACCCCGAtggTTGTAACAATTAAAGACGAACCTGTTGACTTGGACTTTTGTGAGGACAACATTGAAGTCATATCCGAATCTACCAATGATTCAGATTTGGAAGCTACTAATCTCGAAGAGAATATGAATCCTTTAACGAACAATGTCCAAGTAGAATTAACtgatgatgaaattaattttgagaaaaatcaaTCAACTTTAACAAAAGATgtggatataaatataaaatccgaACCACAGGATTATGACACAGATTGTACTATAGAGATAGAATCTGTAACTGGTAGCGAGCTTGTTTTGAATCCTCTTTCAAACACAGAGGATAGGATTATGGAGGCTGATTCTACCCAAAAATCCAATGCATCCACATCAGCAAGTAAGAAAAAAACCAGAAGAGGTCCACATACCCATTTTAGAGGTGCACGtgttttcaaacaaaaatgtGTACATTGTCAAATTAATCTGCActctaaatattcttatacaaAGCACATGGAAAGATTTCACAGTGATAAACAGAATGGCACTAATCAAAAATCAGAATTGGAAGATGAAGAAGAGCTTGTTGAAGATTTAGAAGATGAATTAATGAGCATGGAAAAAGATGCTCCATTAACGCAAGTGCAACAAAACATCATTAGTCAATTGAAAACTTTCATGTGTTATTCTTGCGAACAAACTTTCAGTGATCGTAGAAGTACACTTTCCCATATTCGTCAACATATGCCTGATTTAAGGCCATACACGTGTATTGCGTGTTTGACAGAATTCCCAGATCGCTCGATGTATAAACAGCATTGTAAAATGTCATTCGAATGTGCGATGAAGATTGCACTCGTTATACCGAATCAAGgtgaagagaaatatttcactTGTAATATGTGTTTACGTCCTATGCAGAATAGAAAACAGTTGCTTAGTCATTTATCAAAACACTCGGATAAACAATACGAGGAATTAATATCTCCTACACGATCTCCTCCCAAATTGAAACCAATAACACCCTTACCATCTCCAAAACAAGAAATAATGAAGGAGCCACGCaatgaaagtataaatataccaCATCCTTACAAAAACGGCGATCCTGCGCACAATCATATATGTGATTTGTGCGGTATGATTTACAGGTACAAACCTAATATGCTTAAACACAGAGATCTATGTCAACGTTTATCGTCTGAGGTCAGAACGTCCTATAAGTGTGTTCATTGTGGTATGACGTATCTCGTGTTTAGAAAGTTTCATAGTCATATCACGGCAgatcataaaaagaaagagttcACTTGCTCTGAGTGCAACAAAAAATTCAGATCTCCTAGCGACTTCTTGGAGCATCATGAGATGCATCGAATGGCGCGTAATCAGAAACAGCCTCTTCAATTGAAAAGCGATTTAATGAAGCACAAACAGAATATATCGACGTCGTTCAAGGACtggaataaattcgaaactaAAATGAACGCAAATCAATTATCTGAAAACAATCAATACAGTTGTGCACTGTGCAATCTGGAATTCTCAACCAGAGCTGAATTAACGGAACACAGGAATCTTCATCTGAAAGTGAAAATCTATTCTTGCGTTATCTGTCGTAGCATGTTCAGTAGTGCAGGTGCTTTGGAAATTCATATGAAAGATCATGGAATAGAAGACCCGAATGAGAGAAACGCAAATATTTCGTGCGTAGAATACGGTACCGTAGAAGATGATTCACGAGATTCAAACTCGATGAATTTAAGTGCTATCTCGGATCCAGGACCGaaacataataattgtaaaaaatgtgGAAGACAATTCTCGAACACCGCGAATCTCAAGAgacatataagaaatattcatcCTATCGAGAAACCTCCTTACAATTGCTCTCATTGTTGGCTATCATTTAAGAGCAAAGAAATCCGAGATCAGCACATTACATCCGCACATTCAAAGGCTTCGAAAACTATGCTTCGATGTCCTCAATGTCCACAAACATTTGTCTTCGAAGCCAATCTAGATcttcatttcaaaaatcacCATAAAGATTGCCGTTTCAAATGCGATATTTGCGGTAAAGAGTTCTTGAAGGAAGGCTCGTTGAAGATTCATAGAAGTTGGCACAATAGAGAGAATTATGGACAgagtttgaaatttatgaagaaaGAGGATCAAAAACCATTGGTAGAacctaaaaaagaagaatcgttcAATACGAACGTTAGTGGTCGGCCGGCTAGGGCACGAAAATCCTATCCGAGTTCATCTCCGACAAAACCTAACGGGAATTTCCAATGTCAAGTTTGCAGTGATAAGTTTAACGATGTAACAGAATTGAGGAAACATTTATGGGATGTGCATTGTGCTCGCAATAAAAGCGAGAAGAGCTTTGCAGGTGACGAATTCCAATGCGAACTTTGTACGAATATTTTCCCTGATAAGGAGACGTTGAACGTACACATACAATGGCACAAGGCTCAGCCCATCTTGAGTGACATTCGAAAGACCAATTTCCCTTGTGATATCTGTGGAAAACTTTACAGTTCCAAAAAGGTATTGGCGAGACACAAAAAACTTCATAAAGCGAGCTCGGTGGCTATTAGCAACTTTTCGAGTAATCAGCCTTTATGCACAATTTGTCATAAAGTATTTAACAGTAATCAGTCGTTACAGCGTCACAGGCTTAATTTACACAGCAATATTTTCACTCAACGACCTCAAACGCAACAGTACAATAATACGAGAAGAATGTCTCAAGAAGAATCAAaacctaaaaaaataaaattggaagagGAAGATAAAAAAGTACCATTTGCTATGGATGCCATGAGCGCAGGCAGAAAGTCGGTAATGTGTCACGGctgtaaaaaattcttccctaATATGAGTGTACTGTATAAGCATAAACAATTGGTACATAATAAGTCTCATATGATAAGAAACATCGCGAAATCGCTCACCATGGAATGTGTACCGTTGCATTGCAACGATGGCAAAGTCGCATGCAACATTTGCTATAAAAAGTTCTGCGGTGTGCCGAATCTCCGTCAGCATTTCACTGTGAAACACAAGAATGACCGGCCCAAATATAAGTATGCTTGCTCTATAGATGGCTGTAAGCTCACGTTCCCTACACAATTGACCTTAAAGCATCACGAATTGTCGCATACGGTCACCATGTTCAGCTGCTCCTTGTGCAATAGACACGTGTTTAATAGAGCAGCTATGACGAATCATATGCTGACAGTGCACAACACCGTCTACGACGCCGAGAAGAACAAGAATTTCCATAGAGAAATGGATTTAAGTAGTTACGTGGTGGAAGGTGCGGTAGATGCTACTTGCCCCCGATGTAAAGTGAAGTATCCCAACAACAAGGCTATGAagattcattatttcaaaattcacgaGGGCACGAATCAGTAG
Protein Sequence: MDEVIELQNMENVCRLCLSTDEPKSSVFETEDSPVSLANKIQACLSIQILTTDKLSTKICAQCVKNVNQWHNYKEVCLRSQDKLQQWLEQNLQSTPMVVTIKDEPVDLDFCEDNIEVISESTNDSDLEATNLEENMNPLTNNVQVELTDDEINFEKNQSTLTKDVDINIKSEPQDYDTDCTIEIESVTGSELVLNPLSNTEDRIMEADSTQKSNASTSASKKKTRRGPHTHFRGARVFKQKCVHCQINLHSKYSYTKHMERFHSDKQNGTNQKSELEDEEELVEDLEDELMSMEKDAPLTQVQQNIISQLKTFMCYSCEQTFSDRRSTLSHIRQHMPDLRPYTCIACLTEFPDRSMYKQHCKMSFECAMKIALVIPNQGEEKYFTCNMCLRPMQNRKQLLSHLSKHSDKQYEELISPTRSPPKLKPITPLPSPKQEIMKEPRNESINIPHPYKNGDPAHNHICDLCGMIYRYKPNMLKHRDLCQRLSSEVRTSYKCVHCGMTYLVFRKFHSHITADHKKKEFTCSECNKKFRSPSDFLEHHEMHRMARNQKQPLQLKSDLMKHKQNISTSFKDWNKFETKMNANQLSENNQYSCALCNLEFSTRAELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPNERNANISCVEYGTVEDDSRDSNSMNLSAISDPGPKHNNCKKCGRQFSNTANLKRHIRNIHPIEKPPYNCSHCWLSFKSKEIRDQHITSAHSKASKTMLRCPQCPQTFVFEANLDLHFKNHHKDCRFKCDICGKEFLKEGSLKIHRSWHNRENYGQSLKFMKKEDQKPLVEPKKEESFNTNVSGRPARARKSYPSSSPTKPNGNFQCQVCSDKFNDVTELRKHLWDVHCARNKSEKSFAGDEFQCELCTNIFPDKETLNVHIQWHKAQPILSDIRKTNFPCDICGKLYSSKKVLARHKKLHKASSVAISNFSSNQPLCTICHKVFNSNQSLQRHRLNLHSNIFTQRPQTQQYNNTRRMSQEESKPKKIKLEEEDKKVPFAMDAMSAGRKSVMCHGCKKFFPNMSVLYKHKQLVHNKSHMIRNIAKSLTMECVPLHCNDGKVACNICYKKFCGVPNLRQHFTVKHKNDRPKYKYACSIDGCKLTFPTQLTLKHHELSHTVTMFSCSLCNRHVFNRAAMTNHMLTVHNTVYDAEKNKNFHREMDLSSYVVEGAVDATCPRCKVKYPNNKAMKIHYFKIHEGTNQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00140756; iTF_00141979; iTF_00141363;
90% Identity: iTF_00141363; iTF_00141979; iTF_00140756;
80% Identity: -