Basic Information

Insect: Apis laboriosa
Gene Symbol: ZFHX3
Assembly: GCA_014066325.1
Location: JACEOM010000009.1:443591-451291[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.05 9.5 7.9 0.1 2 23 93 115 92 115 0.96

2 14 0.075 14 7.4 0.1 3 23 136 157 135 157 0.95

3 14 0.00054 0.1 14.1 2.7 2 23 221 243 220 243 0.95

4 14 0.0029 0.55 11.8 1.3 1 23 260 282 260 282 0.97

5 14 0.00012 0.023 16.1 0.2 2 23 289 311 288 311 0.95

6 14 0.0017 0.32 12.6 3.3 1 23 401 425 401 425 0.91

7 14 0.0046 0.88 11.2 0.6 1 22 445 466 445 469 0.89

8 14 0.00062 0.12 13.9 0.2 1 23 510 534 510 534 0.93

9 14 0.072 14 7.4 0.1 2 21 583 602 582 603 0.94

10 14 0.14 26 6.5 2.0 2 19 748 765 747 770 0.91

11 14 9.9e-05 0.019 16.4 2.5 1 23 1373 1395 1373 1395 0.99

12 14 0.0032 0.6 11.7 0.5 1 23 1506 1528 1506 1528 0.98

13 14 0.009 1.7 10.3 0.3 2 23 1671 1693 1670 1693 0.95

14 14 4.5 8.6e+02 1.7 0.3 2 21 1970 1989 1969 1993 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.05	9.5	7.9	0.1	2	23	93	115	92	115	0.96
2	14	0.075	14	7.4	0.1	3	23	136	157	135	157	0.95
3	14	0.00054	0.1	14.1	2.7	2	23	221	243	220	243	0.95
4	14	0.0029	0.55	11.8	1.3	1	23	260	282	260	282	0.97
5	14	0.00012	0.023	16.1	0.2	2	23	289	311	288	311	0.95
6	14	0.0017	0.32	12.6	3.3	1	23	401	425	401	425	0.91
7	14	0.0046	0.88	11.2	0.6	1	22	445	466	445	469	0.89
8	14	0.00062	0.12	13.9	0.2	1	23	510	534	510	534	0.93
9	14	0.072	14	7.4	0.1	2	21	583	602	582	603	0.94
10	14	0.14	26	6.5	2.0	2	19	748	765	747	770	0.91
11	14	9.9e-05	0.019	16.4	2.5	1	23	1373	1395	1373	1395	0.99
12	14	0.0032	0.6	11.7	0.5	1	23	1506	1528	1506	1528	0.98
13	14	0.009	1.7	10.3	0.3	2	23	1671	1693	1670	1693	0.95
14	14	4.5	8.6e+02	1.7	0.3	2	21	1970	1989	1969	1993	0.88

Sequence Information

Coding Sequence: ATGCGGCCCAATTGCACGGTGTGTTCCCATAGTGATTTCCGGTTTTCACCGTGCGGAAATTTCGATGCTTTTAAAACGCCCCTTAAAATTAAGAACAACGCGCTTCAAAACGCATCGCCCGTTGATCTCTTGCCTCAATTACCATGCGAATCCCGGTTACCGTTTTCTTTTCCAGACCGACGAGAGGAAGGTAGCGACTGCGGCAGCGAGGTGAAGCAGGAGCCGGATAACGATCAGGAAACTGAACAAGAGCCGGAGAACGATCACGAGGAAGTCACCTGCCCGTATTGCACTTATCAGCCGACGTCGCGCGAGGAATTGAGGCAGCATTTGCAAGTTGCTCATGTCCAGGACGCCGAGGACAAAGCGGAGGCCGTAAAGGAGGAGCCGCCTCCGGAATTGTTGTGCCCGCTGTGCCAGGACGGGTTCAAAGAGCGTTCCGCGCTCGAGAAGCACGTGATGCAAATACACTCGGTGAACGCGGACGGTTTACAACGTCTTCTGCTGCTGGTTGACCAGAGCCATTGGCTGAACAACAATCCGCGGAACACCTCGACGCCGGCCGTGGCAATGCCGTCCTCACCGACCACCACCATCAAGCAGCCGCAGGAGGAGGATTTGAGCGAGCGCGGGGCCAACGAGGAGATCGAGGAGATCACGAGATGCACCGTTTGCGGCCGTGTTTGCCGCTCGTTGGAGGAGCTGCAGCAACACCACAGGGAGATCCATCCTGCCACTACGCCCACGCTCGCCGTCAGCGAGAAACACGTATACAAGTATCGATGCGGCCAGTGCAGCCTCGCGTTCAAGACGCTGGAGAAGTTGCAACAGCACTCGCAATATCACGCCATCAGGGACGCGACCAAGTGCGCCCTCTGCGGAAGATCGTTTCGCTCGGTGCAGGCGCTCCAAAGACACCTCGAATCCGCCCACGCGGATCTCCACGAGGACGAGTTGGCCCAGTACAAGCAGAGCTTGTTGCACGCCCATCCGCTCCTCCAGGCGCTCACGGAGGAGGCGCTGCGCAGGCAGGGCAGCCTCGTCGGGGAGCAGAACGTCGAGGACGATGCTAGCAAggcggaagaggaggagagcgACGCGAGCGACTCGTCGCCATTGCACAAGGAGCAACGCCTTCTGGAGGATTACCTGAACAGCCAGCCGGTAGCCGAGGATTCTTATCACGATCCAGGGAGAAAGTTCAAGTGTCATCGTTGCAAAGTCGCGTTCACAAGGCAGAGTTACTTGACAGGTCACAACAAGACGTTGCTGCATCGCAAAGGGGAGAAAATGTCTTACCCTATGGAGAAGTATCTGGATCCGAATAGACCGTACAAGTGCGATGTTTGCAAAGAGAGTTTCACTCAGAAGAATATTCTCCTCGTCCATTACAATAGCGTGAGCCATCTGCACAAATTGAAGAGGGCCATGCAAGAGCAAGGTAACAACAACACGTTGATCTCCGTGGTTCCACCTGCCAGTCCGACAGAATCGCCAGATTCTCAGCAAGATCAGGACAAGAAACCGTACAAATGTAACATATGCAAGGTAGCCTATTCCCAAGGTAGCACTTTGGACATTCACATGAGGAGCGTGCTCCATCAGACCAGGGCCAGTAAATTACCAGATCTCGCTGCGAGCGGCCAACTCGACCTCGCGCGTCCCCTGATCGAACAGCCTCCACCTAGCAGCCCTAATAGTCCACCTGTCAACACCAGCACTTCCGGGAATAGCGGTGCAATGCTGTCCTGTCCTCGCTGCAGCGCTCTCTTTGTGAACCAAGAGCAGCTCGCCACCCATCAACAACTGTATTGCATCTTCAGTAATCCTTTGGCGTTGTTTCAACAATTGGCGGCTTCGCAACAGCTCGCTTCGTCCGCGCCAGCGAAAACACCGCCTCCAACCTCCACAACGCCGGGTCCTCAGCAGCACATGCAGCAGAGTGCACAACACTCCACGCAAACCGCCCAGGACATCCTCTCTCAGCCCCGTCACAAGACGTCACAGATGTACAAGCATCTTTTGGAGAGCTTTGGCTTCGATCTGGTGATGCAGTTCAACGAGAATCACCAAAGGCGTCAGcgcaaggaggaggaggcggcaGCTGCGCTTCAGGCCCAGCAGGAACAACAGAAGCAGGAGCAACAGAAACAAGCCCTCGCCGCTCAAGCTGCtcgggagagagaggaagaagccGAGGAGCACACGGATGATGACGTTATACCGGAATTGACCAGAAGCACCTGCCAACATTGCAACAAAGAATTCAGCAGCGTTTGGGTGCTGAAGGCACATTGCGAGGAGGTGCACCGCGACTTGGTGCCTCGAGAATTCTTAGAGAAATACGCTCAACAGTTCAAGTGTGAATACGAGAAGAAAAGCGTGGTGGTGACAGTTGCAACGTCCTCTTCCACGTCATCTGGGCCCAGAAGTTCGACACCAGCTTCTGGCCAACCGCAAGATCTCAGTTCGGACAAAGAGCAACGAGAGAAAGTGAAGGAGGAGATTATCGAGAACAAGGATAGAATCAGTAAAACGCCAGAAGCTACTTCCACGACACCAGCGACCACTCCAGCTCTGAGCAATACTCCAGTGTCGAGTACTGATTCCACCACACCCACTGTGTTGCCAACCAATCCTCAGCATCACATTCAACAGCatcagcagcaacagcagcagcagcaacaacagcagcagcagcagcatcaacaacaacaacaacagcagcagcagcaacagcagcaacaacacGCTCAACTGACTTTGGCACAACAAATGACGGAAATGCAAGCTGCTCTGAACGCTATGGCCGCATCTCAGCTGCAACAACAGCTTCAACAGTATCCTGGATTGATGATGGGTATGATGGGATTACCGCTTGGATTAAATGTTCCTGCTTTGGCTGCTATGAATCTTCAACCCCCATTGGTGCCAATGATGTTACCGCCACCACCGTACGATGGTACAGCCACCGGATATCCGCCTATTAATGCTCAAGCTGATCTCCTAGCCAAACAACATCTCGCCTTGCAGCAGCAACAAGCAGCAGCCGCAAACGCGGCTGCCTCGCAGAAACGAGCGCGAACACGCATTACCGACGAACAGCTAAAGATATTACGGGCGCATTTCGACATCAATAATTCCCCCGGCGAGGAGCAGATTCTAGACATGGCTGCCCAAAGCGGTCTACCGCCCAAAGTGATCAAACACTGGTTCAGGAACACGTTGTTCAAAGAACGGCAGCGCAACAAGGACAGCCCTTACAACTTCAACAATCCGCCTAGCACGACCCTGAATCTCGAGGAATACGAGAAAACGGGGGAGGCGAAGGTGACGCCGTTGAATTCGAGCGTGTCCGGGAGCAGTTCCTCGGACGACAAAAGCCCAAACAAACAGGCGACCCCGCCACCCACGGCCACGTCAGTCAACACGTCCCAGCCAGCCGATATAAAGCAAGAAATTCAAGAGCAGCCGCAGTGCCACGTGCAGCAACAGTCTCAGCATCAGGAGGAGCAACAACATCACTCGCCCGGAAGTTCGGGCGGGCAACAGTCGAGACCGCACTCACCGGCGCTGAGCATGAGCTCGGTATTCTCTGGCATCCATCACGACGTGTCGACGCACGCGCCATCAGCCACCAGCACCCCAAGTGCCCCGATGTTACCGCCAAAACTGGCGCCCCAAAATTTCGCCAGTCCTAATTCGGGGACGAGTAGCGTGGTGGCCAGTCCGATTGCGGCGATGGCGTTGACGCCTCAGAGATCTCTGAGCCCTGGCCGCGGGCCGACCGATTATTCGTTCGGTGGAAGCGCGAACGGAAGTAATTCGTCAGGCGGGAGTTCGGGGAAACGTGCGAATCGGACAAGATTCACCGATTATCAAATCAAAGTGCTGCAAGAGTTCTTCGAAAACAACGCGTACCCGAAGGACGACGACCTGGAATACTTGAGCAAACTGCTGGGATTGAGCCCGCGCGTGATCGTGGTTTGGTTCCAAAACGCTAGGCAGAAAGCCCGAAAGGTGTACGAGAATCAGCCAGCCGCTGAGCCAGTGACACCGGGGGGCCGCGAGGGTGACGACGGTTCGGGCCGCTTCCAGCGGACCCCAGGCTTGAATTACCAATGCAAGAAGTGTTTGCTGGTGTTTCAGAGATACTACGAGCTCATTCGTCATCAGAAGACGCACTGCTTCAAGGAGGAGGACGCGAAGAGGAGCGCCCAAGCGCAGGCGGCCGCGGCCCAAGTAGCCGCGGTTCTCAGTTCCGAAGACAGCAACAGCAGCTCGACCACCACCACTGCTAACGCAGTCTCCACCAATCCTACGAGCGCGCCCGCCCTCGCGGAACAGTTGCAACAACCGTTGAACACAGCTACGCCGCCCCATCATCAGCAACAGGCGATGGGACAGTCGCATCAACAAtcgcagcagcagcaacagcaacaacaacagcagcagcagcagcagcagcaacaacaacaacaacagcagtCGCAGACTGAGTCGAAGGAGGGTAGCTTTCAGTGCGACAAATGCAATCTGATGTTCGGACGATTCGAACTGTGGCGCGAGCATCAGCTGGTACATATCATGAACCCGTCCCTCTTCCCACCCGCTTATCCACCGGACTCACCCTTCGGGATCCTGCAACAGCAGGCGTTGAACGCTACCACGGGAGTGGCGACCGACGCTCCCCACCCGTTGATAGCGATGATGCAGGATAGAAAGAGGAAATACGAGGATTTCGACGAGGGGACAGGTGGCGAATCGCGATCGAATTCCGAGCACAGCGAGCAGCCCAAAGACAAACGACTGAGAACAACCATACTGCCCGAACAATTGGATTACTTGTATCAGAAGTACCAGGTCGAGTCGAATCCATCGAGAAAGATGTTGGAGACCATAGCTCGCGAGGTCGGTTTGAAGAAGCGCGTGGTGCAAGTATGGTTTCAAAATACTCGCGCCCGCGAACGAAAGGGCCAGTTCCGCGCGCACAGCCAGGTGATCAACAAGCGTTGCCCCTTCTGTCCAGCCTTGTTCAAGGTGAAATCCGCCTTGGAGTCGCATCTCAGCAGCAAACACGCCGACCAGGTGGCGCGTGGCGAGGTCAATATCGACAATATCCCGGACGAGGAGCTGTCGATGGAGTCCGCTCCCTCGAACCCTAGCACGCCCAACATGATGCCTCCCCTCTTCCCACCGTTCAACACCGACATGGAGGCGTCGTTGAAAAAGTACTACGAGGAGTCGATGAAGCGATACATCAGCGAGTTGCAGGCCCACGCCAGCAACGGGAAACAAGAGACGGCGAATCATCAGGCGAGCAGCAACAGCGGCGAATCTCCTCTGGATCTGAGCAAACCTGTCGACCTTAGCCGCCCCATGAAACTGAACCTCGGCGGGCTGGGCAATCTCCTCGACGAGCAACACGGCGCTCATTTCCGCGGCGGTAGCGATTGCGGCCCTCTTACCGATCTTTCCGAAAGAAGCATCTGCGATGACGACAGCATGAGCGAGACTACGGAGTTCCTAGACGACGAGAGCGGACCCGCGAGCCCTGCCTCGAGCACGCAAAGCTCGAGACAGGGCCCGGCTTCCGCGGGAGCTGGAAGCACACCTGGCCCACCTGTCACCGGAGCAAGCAGTGGTACAGGCCAATCGAGCGGCAAGAGATATCGAACCCAGATGTCCGCCACCCAAGTGAAGGTGATGAAGTCACTGTTCTCGGACTACAAGACGCCTACGATGGCCGAATGCGAGATGCTGGGGCGCGAAATCGGCCTGCCCAAGCGCGTCGTCCAGGTTTGGTTCCAGAACGCCCGCGCCAAGGAGAAGAAGGCGAGACTGGCCGCGGGTCTGCCCGCCGAGGGCTCGGCCGTCCAACCGAATCGCGGCCCGACCGGGCCCGACGAGTGCAGGCTATGCTCGGTCCGATACTCGGCGAAATCGCCGCTCCAGGAGCACGTATTCTCGCGGCGACACATCGAGTCGGTGCGTGTCGCCGTCGAGGAAGGTAGCCTCGTGCCGCCAACACCCGGCGCGCCGATCGTTCCTGGCGGCAACACGAGCGCAGCGGGGATCGGTGGCTCGCCGGTGGTCGGCAaccagcagcagcagcagcagcaacagcagcagcaatcGGACGAAAACATGATGTACGGATCCTTGTTCCTCCATCCAACGGCGATGTTCCAGCCACAGCAACAGCAACACCCGGGCGCCGCAGCGGCAAGCACGGCTACCACCACGGCCGGTGAGTGTCTGGCTGACCTCTTAGACTCGTAA
Protein Sequence: MRPNCTVCSHSDFRFSPCGNFDAFKTPLKIKNNALQNASPVDLLPQLPCESRLPFSFPDRREEGSDCGSEVKQEPDNDQETEQEPENDHEEVTCPYCTYQPTSREELRQHLQVAHVQDAEDKAEAVKEEPPPELLCPLCQDGFKERSALEKHVMQIHSVNADGLQRLLLLVDQSHWLNNNPRNTSTPAVAMPSSPTTTIKQPQEEDLSERGANEEIEEITRCTVCGRVCRSLEELQQHHREIHPATTPTLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCALCGRSFRSVQALQRHLESAHADLHEDELAQYKQSLLHAHPLLQALTEEALRRQGSLVGEQNVEDDASKAEEEESDASDSSPLHKEQRLLEDYLNSQPVAEDSYHDPGRKFKCHRCKVAFTRQSYLTGHNKTLLHRKGEKMSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLISVVPPASPTESPDSQQDQDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLPDLAASGQLDLARPLIEQPPPSSPNSPPVNTSTSGNSGAMLSCPRCSALFVNQEQLATHQQLYCIFSNPLALFQQLAASQQLASSAPAKTPPPTSTTPGPQQHMQQSAQHSTQTAQDILSQPRHKTSQMYKHLLESFGFDLVMQFNENHQRRQRKEEEAAAALQAQQEQQKQEQQKQALAAQAAREREEEAEEHTDDDVIPELTRSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKSVVVTVATSSSTSSGPRSSTPASGQPQDLSSDKEQREKVKEEIIENKDRISKTPEATSTTPATTPALSNTPVSSTDSTTPTVLPTNPQHHIQQHQQQQQQQQQQQQQQHQQQQQQQQQQQQQQHAQLTLAQQMTEMQAALNAMAASQLQQQLQQYPGLMMGMMGLPLGLNVPALAAMNLQPPLVPMMLPPPPYDGTATGYPPINAQADLLAKQHLALQQQQAAAANAAASQKRARTRITDEQLKILRAHFDINNSPGEEQILDMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLNSSVSGSSSSDDKSPNKQATPPPTATSVNTSQPADIKQEIQEQPQCHVQQQSQHQEEQQHHSPGSSGGQQSRPHSPALSMSSVFSGIHHDVSTHAPSATSTPSAPMLPPKLAPQNFASPNSGTSSVVASPIAAMALTPQRSLSPGRGPTDYSFGGSANGSNSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPVTPGGREGDDGSGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAAVLSSEDSNSSSTTTTANAVSTNPTSAPALAEQLQQPLNTATPPHHQQQAMGQSHQQSQQQQQQQQQQQQQQQQQQQQQQSQTESKEGSFQCDKCNLMFGRFELWREHQLVHIMNPSLFPPAYPPDSPFGILQQQALNATTGVATDAPHPLIAMMQDRKRKYEDFDEGTGGESRSNSEHSEQPKDKRLRTTILPEQLDYLYQKYQVESNPSRKMLETIAREVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLSSKHADQVARGEVNIDNIPDEELSMESAPSNPSTPNMMPPLFPPFNTDMEASLKKYYEESMKRYISELQAHASNGKQETANHQASSNSGESPLDLSKPVDLSRPMKLNLGGLGNLLDEQHGAHFRGGSDCGPLTDLSERSICDDDSMSETTEFLDDESGPASPASSTQSSRQGPASAGAGSTPGPPVTGASSGTGQSSGKRYRTQMSATQVKVMKSLFSDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKARLAAGLPAEGSAVQPNRGPTGPDECRLCSVRYSAKSPLQEHVFSRRHIESVRVAVEEGSLVPPTPGAPIVPGGNTSAAGIGGSPVVGNQQQQQQQQQQQSDENMMYGSLFLHPTAMFQPQQQQHPGAAAASTATTTAGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00141661; iTF_00385825; iTF_00385098; iTF_00089872; iTF_00089361; iTF_00280179; iTF_00279791; iTF_01418835; iTF_01419168; iTF_01453907; iTF_01454439; iTF_01420760; iTF_01421101;
90% Identity: iTF_00141661;
80% Identity: iTF_00141661;