Basic Information

Insect: Tetragonula clypearis
Gene Symbol: ZFHX3
Assembly: GCA_010645135.1
Location: WIUT01004746.1:1-10042[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.049 7.8 8.0 0.1 2 23 34 56 33 56 0.96

2 14 0.073 12 7.4 0.1 3 23 77 98 76 98 0.95

3 14 0.00091 0.15 13.4 3.5 2 23 162 184 161 184 0.95

4 14 0.0028 0.45 11.8 1.3 1 23 201 223 201 223 0.97

5 14 0.00012 0.019 16.2 0.2 2 23 230 252 229 252 0.95

6 14 0.0016 0.26 12.6 3.3 1 23 342 366 342 366 0.91

7 14 0.0045 0.73 11.2 0.6 1 22 386 407 386 410 0.89

8 14 0.00061 0.098 13.9 0.2 1 23 451 475 451 475 0.93

9 14 0.0042 0.68 11.3 0.1 2 21 525 544 524 545 0.94

10 14 0.14 22 6.5 2.0 2 19 689 706 688 711 0.91

11 14 9.7e-05 0.016 16.4 2.5 1 23 1307 1329 1307 1329 0.99

12 14 0.0031 0.5 11.7 0.5 1 23 1449 1471 1449 1471 0.98

13 14 0.0088 1.4 10.3 0.3 2 23 1614 1636 1613 1636 0.95

14 14 4.4 7.1e+02 1.8 0.3 2 21 1913 1932 1912 1936 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.049	7.8	8.0	0.1	2	23	34	56	33	56	0.96
2	14	0.073	12	7.4	0.1	3	23	77	98	76	98	0.95
3	14	0.00091	0.15	13.4	3.5	2	23	162	184	161	184	0.95
4	14	0.0028	0.45	11.8	1.3	1	23	201	223	201	223	0.97
5	14	0.00012	0.019	16.2	0.2	2	23	230	252	229	252	0.95
6	14	0.0016	0.26	12.6	3.3	1	23	342	366	342	366	0.91
7	14	0.0045	0.73	11.2	0.6	1	22	386	407	386	410	0.89
8	14	0.00061	0.098	13.9	0.2	1	23	451	475	451	475	0.93
9	14	0.0042	0.68	11.3	0.1	2	21	525	544	524	545	0.94
10	14	0.14	22	6.5	2.0	2	19	689	706	688	711	0.91
11	14	9.7e-05	0.016	16.4	2.5	1	23	1307	1329	1307	1329	0.99
12	14	0.0031	0.5	11.7	0.5	1	23	1449	1471	1449	1471	0.98
13	14	0.0088	1.4	10.3	0.3	2	23	1614	1636	1613	1636	0.95
14	14	4.4	7.1e+02	1.8	0.3	2	21	1913	1932	1912	1936	0.88

Sequence Information

Coding Sequence: CGACGAGAGGAAGGCAGCGACTGCGGCAGCGAGGTGAAGCAAGAACCGGATAACGATCAGGAGCCGGAACAAGAGCCGGAGAACGAGCACGAGGAAGTCACCTGCCCATATTGCACTTATCAGCCGACGTCGCGCGAAGAATTGAGGCAGCATTTGCAAGTGGCTCATGTCCAGGATGCCGAGGACAAAGCGGAGGCGGTGAAGGAAGAGCCGCCGCCGGAATTGTTGTGCCCGCTGTGCCAGGACGGCTTCAAAGAGCGTTCCGCGCTCGAGAAACACGTGATGCAAATCCACTCGGTGAACGCGGACGGTTTACAACGGCTGCTGTTGCTGGTGGACCAGAGCCACTGGCTGAACAACAATCCGCGAAACACCTCGACGCCGGCGATGGCTATGCCCTCGTCGCCGACCACCACGGCGAAACAACAGCAGGAGGAGGACATGAGCGAGCGCGGGGCCAACGAAGAGATCGAGGAGATCACCAGATGCACCGTATGCGGCCGCGTGTGCCGCTCGTTGGAGGAGCTCCAACAACATCATAGGGAGACCCATCCGGCCACTACGCCCACGCTCGCCGTCAGCGAGAAACACGTTTACAAGTATCGGTGCGGACAGTGCAGCCTGGCGTTCAAGACTCTGGAGAAGCTGCAACAGCACTCGCAGTATCACGCGATCCGGGACGCGACGAAATGCGCGCTCTGCGGAAGATCGTTTCGCTCGGTGCAGGCGCTTCAAAGACACCTGGAGTCGGCGCACGCGGACCTTCACGAAGATGAGATGGCACAGTACAAGCAGAGCCTGATACACGCTCATCCGCTTCTTCAGGCGCTCACGGAGGAAGCTCTGCGCAGGCAGGGCAGCTTGATCGGCGAGCAGAACGTGGACGACGACGCTAGCAaagcggaggaggaggagagcgACGCGAGCGACTCGTCGCCGTTGCACAAGGAACAGCGTCTCCTGGAGGACTATCTCAACAGTCAACCGGTCGCCGAAGATTCGTATCAGGATCCAGGAAGAAAATTCAAGTGTCATCGCTGCAAAGTCGCGTTCACCAGGCAAAGTTACTTGACCGGGCATAACAAAACTCTGCTCCATCGCAAAGGCGAGAAGATGTCCTATCCAATGGAGAAGTATCTAGACCCCAATAGACCGTACAAGTGCGACGTTTGCAAGGAGAGTTTCACCCAGAAGAACATCCTGTTGGTTCATTACAACAGCGTGAGCCACCTGCACAAGCTGAAGAGAGCGATGCAAGAGCAGGGTAACAACAACACGCTCATCTCCGTGATGCCACCCGCCAGTCCCACAGAGTCGCCCGATTCTCAGCAAGACCAGGACAAGAAGCCGTACAAGTGCAACATCTGCAAGGTAGCCTATTCTCAAGGCAGCACGTTGGACATTCACATGAGGAGCGTGCTGCATCAGACCAGGGCCAGTAAACTGCCGGATCTCGCTGCCAGCGGCCAGCTAGATCTCGCTCGTCCGTTGATCGAACAACCGCCGCCAAGCAGCCCGAACAGTCCACCGGTGAACACCAGCAGCACCTCTGGAAACAGCGGGACGATGTTGTCCTGTCCCCGTTGCAACGCCTTCTTCGTCAATCAGGAACAGCTCGCCACCCACCAGCAACTTTATTGCATATTCAGCAATCCTTTGGCGTTGTTTCAACAGCTGGCGGCGTCTCAGCAGCTCGCGTCAACTCCAGCCAAAACTCCGCCGCCAACGTCCACGACGCCCGGCTCGCAACAGCACTTGCAACAAGCCACGCAACATTCCTCGCAAACAACGCAGGACATTCTGTCTCAGCCTCGCCACAAGACCTCGCAGATGTATAAACACCTCCTGGAGAGTTTCGGTTTCGATCTGGTGATGCAGTTCAACGAGAACCATCAACGACGCCAGCGCAAAGAGGAGGAGGCTGCGGCCGCGCTTCAAGCGCAGCAGGAACAACAGAAACAGGAACAGCAGAAGCAGGCACTGGCTGCTCAAGCCGCGCGCGAAAGGGAGGAGGAGACGGAGGAACATACCGACGACGATGTCATACCGGAGCTAACCAGGAGCACTTGTCAGCACTGCAACAAGGAATTCAGCAGCGTCTGGGTGTTGAAGGCTCATTGCGAGGAGGTGCATCGTGACTTGGTGCCGCGCGAATTCTTGGAGAAGTACGCCCAGCAATTCAAGTGCGAGTACGAGAAGAAGAGCGTCGTGGTGACTGTCGCGACGTCCTCTTCCACGTCGTCCGGACCCAGAAGCTCGACACCGGCCTCCAGCCAACCGCAGGATCTCTCCTCGGACAAGGAACAACGCGAGAAGGACAAGGAGGATATGAACGAGAGCAAAGATCGAGTCAGCAAGACCCCGGAGGCTACTTCCACCACGCCGGCAACAACTCCGGCGTTGAGCAACACGCCAGTGTCGAGCACCGATTCTACAACGCCAACCGTGTTGTCCACCAATCCTCAGCTTCATAttcaacagcagcagcaacaacagcagcagcaacaacaacagcaacaacagcaacagcaacaacagcacGCTCAGTTGACACTGGCGCAACAGATGACAGAGATGCAAGCCGCTTTAAACGCGATGGCTGCGTCTCAACTGCAGCAGCAGCTTCAACAGTATCCTGGACTGATGATGGGCATGATGGGTTTACCCCTTGGATTGAACGTTCCCGCTCTGGCTGCCATGAATCTTCAACCACCGTTGGTGCCAATGATGCTACCACCGCCGCCGTACGACGGAACGGCTACCGGATATCCACCCCCTATCAATGCACAAGCCGATCTCCTTGCCAAGCAACATCTCGCCTTGCAGCAGCAACAAGCAGCAGCCGCAAACGCGGCTGCCTCGCAGAAACGAGCGCGAACGCGCATTACCGACGAACAGCTAAAGATATTACGAGCGCATTTCGACATCAACAATTCCCCCGGCGAGGAACAGATTCTAGATATGGCGGCTCAGAGCGGGCTACCGCCGAAAGTCATCAAACACTGGTTCAGAAACACGTTGTTCAAAGAGCGGCAGCGGAACAAGGACAGTCCGTACAACTTTAACAACCCACCGAGCACAACGTTGAATCTCGAGGAGTACGAAAAGACTGGCGAGGCGAAAGTGACGCCGTTGAACTCTAGCGTGTCCGGGAGTAGTTCCTCGGACGACAAAAGCCCGAACAAACAGGCGACACCGCCACCGTCGACCGCCGCACAAGTGAACACGTCGCAGGCCAGCGAGATCAAGCAGGAGATTCAAGAACAGCCGCAGTTGCACGTTCAGCAACATTCGCAGCATTCGCAGGAGGAGCAGCAACATCATTCGCCCGGTAGTTCCGGCGGACAGCAGTCGAGACCGCACTCGCCGGCGCTCAGCATGAGCTCCGTGTTCTCTGGGATTCATCACGACGTGTCGTCGCACGGCGCATCGACCGTCAGCGCTCCAAGCACGCCGATGCTACCCCCGAAGCTGGCACCGCAAAACTTCACCAGCCCGACCCCCGGTGCCGGTAACGTGGTCCCGGGGGCGATCGCGGCAATGGCTCTGACGCCTCAACGATCACTCAGCCCTGGTCGTGGACCGACCGATTACTCCTTCAGCGGAAGCACCAACGGCAACAGCTCCTCGTCCGGCGGTAGCTCCGGCAAACGAGCCAACAGAACGAGATTCACCGACTATCAGATCAAGGTGCTTCAGGAGTTCTTCGAGAACAACGCGTACCCGAAAGACGATGACTTGGAGTATCTGAGCAAGCTGCTCGGGCTGAGCCCGCGCGTGATCGTGGTATGGTTCCAGAACGCTAGGCAAAAAGCGCGAAAGGTGTATGAAAATCAGCCAGCCGCTGAACCAGTGACGACGGGCAGCCGCGAGGGTGACGACGGTTCAGGCCGATTCCAACGGACCCCAGGCTTGAATTACCAATGCAAGAAGTGTTTGCTGGTGTTTCAGAGATACTACGAGCTCATTCGTCATCAGAAGACGCACTGCTTCAAGGAGGAAGACGCGAAGAGGAGCGCCCAAGCGCAGGCAGCCGCGGCCCAAGTCGCCGCTGTTCTTAGCTCCGAAGACAGCAACAGCAgttccaccaccaccactgcTAACGCCGTGTCCAGTAATCCGATCAACACTCCCGCACTCGCGGAACAGTTACATCAGCCGTTGAACGCCACCACGTCTCCTCATCatcagcaacagcaacaaatGGGACAGTCGCATCAACATCCTCAGCAACAGtcgcagcagcaacagcagcaacagcaacagcaacagtcgcagcagcagcaacagcaatcGCAGCAGCAACAACCGCAACAGTCGCAGACCGAGTCGAAGGAAGGTAGCTTTCAGTGCGACAAGTGTAACCTGATGTTCGGGCGGTTCGAACTGTGGCGCGAACATCAGCTAGTACATATCATGAACCCGTCCCTGTTCCCACCCGCCTATCCGCCAGACTCACCGTTCGGCATCCTCCAGCAACAAGCGCTGAACGCTACCAGCGGGGTAGCCGCCGATACCCCTCACCCTTTAATCGCGATGatgcaagagagaaagagaaagtacGATGACTTCGACGAGGGAACGGTCGGCGACAGCCGCTCCAACTCCGAGCACAACGAGCAGCCGAAGGACAAGCGACTGAGAACGACGATATTGCCTGAACAGTTGGATTATTTGTATCAAAAGTACCAAGTCGAGTCGAATCCGTCGAGGAAGATGTTGGAGACGATCGCTCGCGAGGTCGGCCTGAAGAAACGGGTGGTGCAAGTGTGGTTCCAGAATACGCGCGCCCGCGAACGGAAGGGCCAGTTCCGCGCGCACAGCCAGGTGATCAACAAACGGTGCCCCTTCTGTCCGGCCTTGTTCAAAGTGAAGTCAGCCCTAGAATCGCATCTGAGTAGCAAACACGCCGATCAGGTGGCTCGCGGCGAAGTGAATATAGATAACATTCCGGATGAGGAACTCTCGATGGAGTCGGCCCCCTCGAACCCGAGCACGCCCAACATGATGCCGCCGCTGTTCCCGCCGTTCAACACCGAAATGGAGGCGTCTCTGAAAAAGTACTACGAGGAGTCGATGAAGCGATACATCAGCGAGCTGCAGGCTCACGCCAGCAACGGCAAGCAAGAGACCGCTAACCATCAGGCGGGTGGCAACAGCGGCGAGTCGCCGTTGGATCTGAGCAAACCGGTAGATCTGAGTCGCCCGATGAAATTGAGCCTCGGCGGGCTGTCGAATCTCCTCGATGAACAACACAGCGCGCACTTCCGCGGCGGCAGCGACTGCGGTCCGCTGACCGACCTCTCCGAGAGGAGCATCTGCGACGACGACAGCATGAGCGAGACCACGGAATTCCTAGACGACGAGAGCGGACCGGCGAGTCCAGCCTCGAGCACACAGAGTTCCAGACAGGGTCCCGCTTCGGCGGGGGCCGGAAGTGCCGCGGGCCCGCCGGTCGCCGGCGCCGGCAGCGGGACAGGCCAATCCAGCGGCAAGCGATATCGCACCCAGATGTCCGCTACCCAGGTAAAGGTGATGAAGTCGCTGTTCTCGGACTACAAGACGCCCACCATGGCCGAGTGCGAGATGCTCGGACGCGAGATCGGACTGCCGAAGCGCGTGGTTCAGGTGTGGTTCCAGAACGCCCGTGCAAAAGAGAAGAAGGCTAGACTGGCGGCCGGTTTGCCGGCCGAAGGCTCGGCCGTCCAACCTCATCGCGGCCCGACCGGCCCGGACGAGTGTAGACTCTGCTCGGTTCGATACTCGGCCAAGTCGCCGCTTCAGGAGCATGTATTCTCGCGGCGACACATCGAGTCGGTGCGTGTCGCCGTCGAGGAGGGTAGCCTCGTGCCGCCAACACCCGGCGCACCGATCGTTCCTGGCGGCAACAGCGGCGCAGCAGGAATCGGTAGCTCGCCGGTGGTCGGACCTGGTAACCAGCAAACcagccagcagcagcagcaatcGGACGAAAACATGATGTACGGATCCTTGTTCCTCCATCCAACGGCGATGTTCCAGtcacagcaacagcaacaccCGGGCGCCGCAGCGGCTAGCACGGCTACCACTACCGCCGGTGAGTGTCTGGCTGACCTCTTAGACTCGTAA
Protein Sequence: RREEGSDCGSEVKQEPDNDQEPEQEPENEHEEVTCPYCTYQPTSREELRQHLQVAHVQDAEDKAEAVKEEPPPELLCPLCQDGFKERSALEKHVMQIHSVNADGLQRLLLLVDQSHWLNNNPRNTSTPAMAMPSSPTTTAKQQQEEDMSERGANEEIEEITRCTVCGRVCRSLEELQQHHRETHPATTPTLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCALCGRSFRSVQALQRHLESAHADLHEDEMAQYKQSLIHAHPLLQALTEEALRRQGSLIGEQNVDDDASKAEEEESDASDSSPLHKEQRLLEDYLNSQPVAEDSYQDPGRKFKCHRCKVAFTRQSYLTGHNKTLLHRKGEKMSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLISVMPPASPTESPDSQQDQDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLPDLAASGQLDLARPLIEQPPPSSPNSPPVNTSSTSGNSGTMLSCPRCNAFFVNQEQLATHQQLYCIFSNPLALFQQLAASQQLASTPAKTPPPTSTTPGSQQHLQQATQHSSQTTQDILSQPRHKTSQMYKHLLESFGFDLVMQFNENHQRRQRKEEEAAAALQAQQEQQKQEQQKQALAAQAAREREEETEEHTDDDVIPELTRSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKSVVVTVATSSSTSSGPRSSTPASSQPQDLSSDKEQREKDKEDMNESKDRVSKTPEATSTTPATTPALSNTPVSSTDSTTPTVLSTNPQLHIQQQQQQQQQQQQQQQQQQQQQHAQLTLAQQMTEMQAALNAMAASQLQQQLQQYPGLMMGMMGLPLGLNVPALAAMNLQPPLVPMMLPPPPYDGTATGYPPPINAQADLLAKQHLALQQQQAAAANAAASQKRARTRITDEQLKILRAHFDINNSPGEEQILDMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLNSSVSGSSSSDDKSPNKQATPPPSTAAQVNTSQASEIKQEIQEQPQLHVQQHSQHSQEEQQHHSPGSSGGQQSRPHSPALSMSSVFSGIHHDVSSHGASTVSAPSTPMLPPKLAPQNFTSPTPGAGNVVPGAIAAMALTPQRSLSPGRGPTDYSFSGSTNGNSSSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPVTTGSREGDDGSGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAAVLSSEDSNSSSTTTTANAVSSNPINTPALAEQLHQPLNATTSPHHQQQQQMGQSHQHPQQQSQQQQQQQQQQQSQQQQQQSQQQQPQQSQTESKEGSFQCDKCNLMFGRFELWREHQLVHIMNPSLFPPAYPPDSPFGILQQQALNATSGVAADTPHPLIAMMQERKRKYDDFDEGTVGDSRSNSEHNEQPKDKRLRTTILPEQLDYLYQKYQVESNPSRKMLETIAREVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLSSKHADQVARGEVNIDNIPDEELSMESAPSNPSTPNMMPPLFPPFNTEMEASLKKYYEESMKRYISELQAHASNGKQETANHQAGGNSGESPLDLSKPVDLSRPMKLSLGGLSNLLDEQHSAHFRGGSDCGPLTDLSERSICDDDSMSETTEFLDDESGPASPASSTQSSRQGPASAGAGSAAGPPVAGAGSGTGQSSGKRYRTQMSATQVKVMKSLFSDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKARLAAGLPAEGSAVQPHRGPTGPDECRLCSVRYSAKSPLQEHVFSRRHIESVRVAVEEGSLVPPTPGAPIVPGGNSGAAGIGSSPVVGPGNQQTSQQQQQSDENMMYGSLFLHPTAMFQSQQQQHPGAAAASTATTTAGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00142019;
90% Identity: iTF_01420760;
80% Identity: iTF_01418835;