Ador006713.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis dorsata
Gene Symbol
E2f2
Assembly
GCA_000469605.1
Location
NW:160154-165612[+]

Transcription Factor Domain

TF Family
E2F
Domain
E2F_TDP domain
PFAM
PF02319
TF Group
Helix-turn-helix
Description
This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.6e-31 1.4e-27 94.3 0.3 2 65 136 199 135 199 0.98

Sequence Information

Coding Sequence
atgcCTCGAGTAAGGAGACAAGTGGTCTTAGAAGATCCTGCTAGGCCTGTCACACCAGATATGGTGGAGACTAAATTACtaaagGAAGAATTTTTAGATGAGGGCTCTTTGGATGAAGTACAAGCACAAAAAGTAGCTGAAGAAACACCAAGTCCTCATCTTCAAGACCACCAATATGGACAAACACCTTGTTATCAAGTAACAAGGAAACCTACACAACCACCACCACGAACTGAacaAATTTCAGTTCAAGCAGTGAAACGAAGACTGAATTTGGAAATGGGAACTACAGGCCCTAGCCAATCTGCTTTTAAAGCTCCTAGAGGTAAACGTAGAAAATCTGGATCAAGTTCTCTAGCTGGCCATACACCtacaaaaaGTAAAACAGTAGAGAGAACGCGGTACGATACATCACTGAGCTTACTTACAAAAAAGTTCATACATTTAGTTGAAAGCAGTCAAGATGGTGTTGTAGATTTAAATGTAGCATCTGAAAAATTAGAAGTACAGAAACGTCGTATTTACGATATTACGAATGTATTGGAAGGTATAGGtattttggaaaagaaaagtaaaaacaatatacaatGGAAagGCGGTCAATTACCAAATGAAAGGAACGATATCGCTGATCTCAGAAAAGAAGTGGCAGATTTAGAAGCTAAAGAAAATACTTTGGATCGATTAATTCATGGTGCAGACAAAAATCTTAGGGAGCTCTGTGCAGACAGACAATACGCTTATGTAACGTATCATGATTTACGTTCTGTCCCAATGTACAAAGACCAAGCTATAATGGCAGTGAAAGCTCCACCAGAAGCTACACTTCATGTTCCACAACCTATTAATAATCTTGGTCAACAAAAGCTTCAAATGCATATGAGGTCATCTCATGGTGAAATAGAGGTATTTCTTTGTCCTGATGATCCTGCAGTTAAAACGTCTCCCACTCCGGGTTACACGACGACGCAACCTGTGCCTTCGTCAAAAGAATCCGAAATACCTTGTCTCCCTCCTGAACTGCTGGCCAATGGAGGAAGCGGGGTTCGGGTTGAACCAGTACCTTCTATCGAAAGTTCGTTGAGTACTCGTTTGTGTACTCCGGTTATATCTACAGTTACCAGTTTAGCAGGCATGAGGGACGCGCTTTTGTGTGAATCCGATGATTATGGACCAATGGGTGGTGGCAAATTCCAACTCCAAACGGAGGATCAAATTAGCACTCCAGATCTAAGTATTCTCGATTTTGGTGAGCATCTACTGTCCCTGGAACCGCCTCTTTCTGAAAACGACTATTCGTTCTCGTTAGGCACAGAGGAAGGGCTTTCGGATCTCTTTGATTTCAAATTCTAA
Protein Sequence
MPRVRRQVVLEDPARPVTPDMVETKLLKEEFLDEGSLDEVQAQKVAEETPSPHLQDHQYGQTPCYQVTRKPTQPPPRTEQISVQAVKRRLNLEMGTTGPSQSAFKAPRGKRRKSGSSSLAGHTPTKSKTVERTRYDTSLSLLTKKFIHLVESSQDGVVDLNVASEKLEVQKRRIYDITNVLEGIGILEKKSKNNIQWKGGQLPNERNDIADLRKEVADLEAKENTLDRLIHGADKNLRELCADRQYAYVTYHDLRSVPMYKDQAIMAVKAPPEATLHVPQPINNLGQQKLQMHMRSSHGEIEVFLCPDDPAVKTSPTPGYTTTQPVPSSKESEIPCLPPELLANGGSGVRVEPVPSIESSLSTRLCTPVISTVTSLAGMRDALLCESDDYGPMGGGKFQLQTEDQISTPDLSILDFGEHLLSLEPPLSENDYSFSLGTEEGLSDLFDFKF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00141633; iTF_00142277; iTF_00140381; iTF_01254593; iTF_01266690; iTF_01268810; iTF_01267340; iTF_01270990; iTF_01269590; iTF_01270298; iTF_01268064; iTF_01497988; iTF_00756421; iTF_00863754; iTF_00762347; iTF_00861681; iTF_00860179; iTF_00763034; iTF_00860922; iTF_00863071; iTF_00864435; iTF_00865118; iTF_01098987; iTF_00292077; iTF_01394916; iTF_01475236; iTF_01472966; iTF_01474472; iTF_00298094; iTF_00296560; iTF_00295029; iTF_00253353; iTF_00251855; iTF_00254870; iTF_00254106; iTF_00252604; iTF_01473705; iTF_00295794; iTF_00770162; iTF_01130600; iTF_01198456; iTF_01199194; iTF_00297333; iTF_00292728; iTF_00294255; iTF_00291322; iTF_00293504; iTF_00633421; iTF_00391085; iTF_00865805; iTF_01354413; iTF_01015599; iTF_01355104; iTF_00385070; iTF_00125700; iTF_00127237; iTF_00127976; iTF_00129518; iTF_00884848; iTF_00128755; iTF_00765333; iTF_01523160; iTF_00126492; iTF_01520022; iTF_01418159; iTF_00982083; iTF_00873607; iTF_00982759; iTF_01419441; iTF_01418806; iTF_01420090; iTF_01420731; iTF_00084323; iTF_00183747; iTF_00224355; iTF_00214820; iTF_00216868; iTF_00218213; iTF_00230502; iTF_00225705; iTF_00227753; iTF_00231113; iTF_00219596; iTF_00225036; iTF_00228461; iTF_00215502; iTF_00223669; iTF_00226389; iTF_00218906; iTF_00222331; iTF_00232412; iTF_00221053; iTF_00221725; iTF_00229150; iTF_00227071; iTF_00233028; iTF_00229825; iTF_00983428; iTF_01539396; iTF_00683963; iTF_00684606; iTF_01168965; iTF_00085959; iTF_00866503; iTF_01424167; iTF_00962984; iTF_00963661; iTF_01122227; iTF_00964276; iTF_00961622; iTF_00962300; iTF_01122876; iTF_00222985; iTF_00675818; iTF_00087723; iTF_00086893; iTF_00217549; iTF_00760785; iTF_00117797; iTF_00024434; iTF_00625295; iTF_00085077; iTF_00965846; iTF_00216183; iTF_01453879; iTF_00214200; iTF_00231788; iTF_00220377; iTF_00862361; iTF_00088573; iTF_01417502; iTF_00306047; iTF_00360703; iTF_00360010; iTF_01070847; iTF_00302832; iTF_00754384; iTF_00393393; iTF_01255330; iTF_01077265; iTF_00264802; iTF_00730529; iTF_00264068; iTF_00280452; iTF_00109621; iTF_00729087; iTF_00729856; iTF_01245016; iTF_00868562; iTF_00867188; iTF_00867933; iTF_00773587; iTF_01406291; iTF_01421350; iTF_01405481; iTF_01422027; iTF_01423435; iTF_01407021; iTF_01408849; iTF_01407958; iTF_01422715; iTF_00183092; iTF_01228184; iTF_01228814; iTF_01261660; iTF_00015845; iTF_00016489; iTF_00181769; iTF_00417354; iTF_01475980; iTF_00015184; iTF_01476725; iTF_01477368; iTF_00014521; iTF_00181113; iTF_01089789; iTF_00452383; iTF_01087010; iTF_00769425; iTF_01512639; iTF_01068769; iTF_01070149; iTF_01067403; iTF_01068077; iTF_01066739; iTF_01234145; iTF_01234817; iTF_01232215; iTF_01233439; iTF_01065346; iTF_01232807; iTF_01513265; iTF_01514627; iTF_01513958; iTF_01066035; iTF_01069443;
90% Identity
iTF_00306047;
80% Identity
iTF_00142277; iTF_00140381;