Agos000224.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphis gossypii
Gene Symbol
-
Assembly
GCA_004010815.1
Location
NW:97289-103820[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.019 1.4 9.0 2.3 2 21 112 131 111 132 0.94
2 21 1.5e-05 0.0011 18.7 1.0 1 23 139 161 139 161 0.98
3 21 2.2e-06 0.00017 21.4 0.6 2 23 168 189 167 189 0.98
4 21 0.0012 0.092 12.8 1.4 1 23 195 217 195 217 0.98
5 21 8.8e-06 0.00066 19.5 3.8 1 23 223 245 223 245 0.98
6 21 6.3e-06 0.00047 20.0 2.4 1 19 253 271 253 275 0.95
7 21 2.5e-07 1.8e-05 24.4 4.5 1 23 281 303 281 303 0.99
8 21 1e-07 7.6e-06 25.6 0.7 1 23 309 331 309 331 0.98
9 21 1.8e-05 0.0014 18.5 3.5 1 23 337 359 337 359 0.98
10 21 7.4e-06 0.00056 19.7 4.2 1 23 365 387 365 387 0.98
11 21 0.0001 0.0077 16.1 1.5 1 23 393 415 393 415 0.97
12 21 3.7e-08 2.8e-06 27.0 2.0 1 23 421 443 421 443 0.99
13 21 2.4e-06 0.00018 21.3 2.1 1 23 449 471 449 471 0.99
14 21 6.3e-05 0.0047 16.8 3.1 1 23 477 499 477 499 0.97
15 21 5.3e-05 0.004 17.0 0.5 1 23 505 527 505 527 0.98
16 21 1.7e-05 0.0013 18.6 1.0 1 23 533 556 533 556 0.97
17 21 0.00012 0.0089 16.0 0.7 1 23 562 584 562 584 0.99
18 21 1.8e-06 0.00014 21.7 1.9 1 23 590 612 590 612 0.97
19 21 1.6e-07 1.2e-05 25.0 0.9 1 23 618 640 618 640 0.99
20 21 0.00022 0.016 15.1 0.8 1 23 646 668 646 668 0.97
21 21 5.6e-07 4.2e-05 23.3 0.4 1 23 674 696 674 696 0.98

Sequence Information

Coding Sequence
atggagTTAAGAACAACTTCAAATGATGCCAAAATCTCTTCCAAatatggttatatattaaacaattctaGACAGTTGATAATTCCACTTATTAGATGTGATCATTTACTCAATCGACCATCTAATGTAGTTATTAAACAAGAATTTATTGCCAAGACGGAGTATCATAATGATAGTCAATTATTACAAAGTGGgacTGTACATAAAACTGGAGAAAAagtaaacacaaatattactgatataaaaatcgaaaatgattatatcgataataatgtatttgaaagTATAGTTGTTAGGCAAGATCACTCTTCAAACTTTCTGGAAAATACCTTAACATGCGAATTgtgttgtaaaaaatttactgATGAATTCAGTATGAGAAgacatatgaaaatatatagggGAAAACCCACTTTTACATGTGAAATATGTAAACAATCATTTCATCAAAAACCACAGTTGATCgctcatattttaaatcacacAGAAGATAAATCTAACAAATGTGgtgtttgtaataaaatgtttacaagaAATGGATATGTAAAAATTCATATGAGGATCCATACTGGAGAAAAGCCGTATgaatgtaatttatgtaatcaaaaatatgcTCACAGAGGAGGTTATGACATTCATATGAAAAATCATACTGGATTGAAACCGCACAAATGTGGTTTATGTAATGCATCATTTAGTTTAAAAGGCCATTTGAAAAGACATATGTTGACTCATACCAGTAAAAGAGAAAGGACATATGTTTGTGACATTTGTAATAAGTCTTACTATAATAGTTCACATTTGAAAAGACACAAATGGCTTCATTCTGCAGAAAAACCTTATAAATGCACTATCTGTAATAGAACATTTTCAGACACGAGCCATCTCAAAACACACACAAGAATTCATACTGGTGAAAAGCCTTTTAAATGTGAAATTTGCAATAAatcttttattgtaaaatcaagtTTGACAATACATATGATGAATCACACAGGGTTGAAACCTTTCAAATGTAAAGACTGTTTTAAGACATTCAGTAATATGACACGACTGAAATCACATATGTCAGTTCATACAGGAGAAAAACCATTCGAATGTAGCATctgtcataaattattttctaaatcaaCCAATTTACAATACCATATGATGAAACATAAAGACGAAAATCCTCATAAGTGTTTCGTGTGTAATAAAACATTCGCAATcgcatcatttttaaaaagccATATGGTTATTCATTCTTCCAACAAGccttataaatgtaatgtttgtGATAAGGTATTTTCCCAggcaatacatttaaaagttcATACTAGAACACATACTGGGGAAAAACCTTATAAATGTGATATTTGTTACAAATCATTTTCGGTATCTAATTCTTTAACTTTACACAAGAGAACTCATACTGGGGAAAAGCCGTTTAAATGTGAAATATGTGATTATAGATGTACAACATCTTcttcattaataattcataacagATTTCATTCTGGGAAGAAACCTTATAGTTGTGATGTATGTAACAAGGCATTTGTTGCTACTTCACTTTTAACTGTACATAAAAAGAAACATACAGGAGACAAACCGTTTAAATGTGACTTATGTCCTAgaacatttattcaaaaatctaCTATAAGAATGCACATTATGAGTTTTCATTCTAAATTCAGACCTTATAAGTGTGATGTTTGTAAGAACTCATATgcttcaaaatcaattttgaaattacatATGAGAATACACACTGGAGAATCCCCTTTTACTTGTGGTATCTGTAATAAATCATTTCGTCATAAACCACTATTGAaaagtcatattataaacCATACAGGAGAAAAAGCTTATAAGTGTAAAATTTGTTCGAAAGCGTTTACTAATAGCTCAGGTGTTAAAATGCACATGAGAATTCATACTGGTGAAAAACCATATAAGTGTGATTTATGTACGAGAGGATTCCGTTATAAAGGAAGTTTTGATATTCACATGGCCCAGCATACTGGGTTAAAACCCTTTAAATgtgatatatgtaataaagcCTTTGCTGTGAAATCAAGATTGATTCGGCATATGAGTATTCatactaatgagtaa
Protein Sequence
MELRTTSNDAKISSKYGYILNNSRQLIIPLIRCDHLLNRPSNVVIKQEFIAKTEYHNDSQLLQSGTVHKTGEKVNTNITDIKIENDYIDNNVFESIVVRQDHSSNFLENTLTCELCCKKFTDEFSMRRHMKIYRGKPTFTCEICKQSFHQKPQLIAHILNHTEDKSNKCGVCNKMFTRNGYVKIHMRIHTGEKPYECNLCNQKYAHRGGYDIHMKNHTGLKPHKCGLCNASFSLKGHLKRHMLTHTSKRERTYVCDICNKSYYNSSHLKRHKWLHSAEKPYKCTICNRTFSDTSHLKTHTRIHTGEKPFKCEICNKSFIVKSSLTIHMMNHTGLKPFKCKDCFKTFSNMTRLKSHMSVHTGEKPFECSICHKLFSKSTNLQYHMMKHKDENPHKCFVCNKTFAIASFLKSHMVIHSSNKPYKCNVCDKVFSQAIHLKVHTRTHTGEKPYKCDICYKSFSVSNSLTLHKRTHTGEKPFKCEICDYRCTTSSSLIIHNRFHSGKKPYSCDVCNKAFVATSLLTVHKKKHTGDKPFKCDLCPRTFIQKSTIRMHIMSFHSKFRPYKCDVCKNSYASKSILKLHMRIHTGESPFTCGICNKSFRHKPLLKSHIINHTGEKAYKCKICSKAFTNSSGVKMHMRIHTGEKPYKCDLCTRGFRYKGSFDIHMAQHTGLKPFKCDICNKAFAVKSRLIRHMSIHTNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00134721;
90% Identity
iTF_00135582;
80% Identity
-