Agly006468.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphis glycines
Gene Symbol
-
Assembly
GCA_009928515.1
Location
scaffold:837620-848325[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 7.3e-14 3.5e-10 39.4 0.0 9 72 157 225 153 228 0.94
2 2 0.016 79 3.1 0.0 21 70 347 393 341 399 0.72

Sequence Information

Coding Sequence
ATGGATAAATCGGAGAGAAAGAAATCTGCTGGTTTAAAAGAAACCAATAATCTTTTAAACCTTGAAGCACATTTTCTTGGATTTGATATTGATGATGAAGTATTGATAGTTATTGAAAATAAGAAAAAATCATTAAAAATGGAACTTAGTAAAGAAACTGGTGAACCTATGGAAGTGGATGACCCAACCGACAGTCCATCCATTGTTAACAACAATCATGTTAATAAAAAGAAAAAATCTAAATCAAGTATATCATCACCAGAGCCCAGTGATGTTAAGAACAGCCGGAGTAATAAGAGGCAAAAGAAAGACAACAAAAACAATGATGCCTCAGAATCCTTGGAATTAGATGTTACACCTCCTTTAGAACTTACTACTCCAACATTCAACTTGACCTCTTCTAACACTAGATCACGCCGTAGTACAGGCAGAAAAATGAATGTTGATATCAGTGATGCTCTTTTTAAACTTCCATTTGAATTTGGATGGAAACGAGAATTAGTATACAGAACTTCAGGTGAATCTACTATTATTAATCGAGGAAATAGAAGTGGTGATGTATACTATTATTCTCCAAATAACCGAAAACTTCGATCTTTACGAGAAATTCAGGAACAATTGGACGCTGATAGTGAAAATGTTCTCACTATAGATAGTTTTACTTTTTTAAAACAACCAATTGGCATGAATGACCGATCAAAAGAACTGATCAGAGATGCCAATTCCAAATTATCTAAGGAAGACTCTTTTATTGCTATTCGACCTAAAAAATCTAAAACACCTGTACAGCAGCGACCACCATTTGATTATGAATTATCAGATGATGAAAACAACAAGTCTTCAAGTAAAATGAAAATTGTTTTTAAAAGTGGAAAGACTCCTAGATCTAGATCTAAAAAAGTGAATTCAGAATCAATGAATACATCTTCATCTACACCTGAATACATAGCTGAAGACTGGCAAGCTATTCAATCTAGTGTATCACCAAAAGTTTTTTCTCCTAAACTTGAGAATAATGATATAAATACCTCAACCACTAAAAGACGGTCGTCAACATCAGATGGGGAAGTTATCATGCAGACTCCTTGTGGTATACGGTGCCCTAATAGTGATGAACCTGCCACTCTAATGTGTGCTCAATGTCTAGTCTACTATCATCCAGCATGTGTCAATTTAAATGCTAATTTAAAAATTGTTGGTTATGTATGTATAAACTGTCGATCTACTGTGCGACAAAGAAATAGACGTGTACAGTCATCTCATACTGTAGTTGTTGGTGCTACTGAACCAGAACAACTACGCGTTGAACCAATTCGTATACGACAAGTTCATCAAGCATCAGATACTCCTAATTTCTTTATTGATAGAACACCTATTTCTAAAATTGAAGAATCACACTATGAAATTGATGAATATAGTGATGAAAGTGAATCTGATATAATAAATACTGTTATATGTCAAGGAAATGAATACAAAACTACAATGGTTGATGGTAATTTTCATGAGCAGTATGTTTATGAAATGAAACAAACACGAGGACCTAGTTTGATGACTTGTGTTATTCAAGAGCCCAACAATTTAGATGAGAATTCTGAAATGAATGGTTCATTAAGAGATATTGCAACATCTTCCACTTCCACTTCCATGCAATCATTCAACTACATGGCTAAAGCATTGAGACACGTCTTTAAATATCTAAAAACGCATGAACTTTTATCAGCTTCTAGAGTATGTACCGCTTGGCATATAATTGCAATGAATAAGTTCTTATGGCAAAATGTTCGTCTAAAAAATTCTATGGTCTATGATTGGGAAAGGTTTGTAAACACTATTGAACAACAATTAACTCATACTTTAGACACTAGACGAATGTTGATACCTTCAAAAGTTGAAGAATTTGAAGATTTTTGGTTGAATTTTTCGAAAGCCATGAAAAGAGCACAAAAGTTGAAATTAATTGAATTGTATAGATGTCCTACTCATGTAGTTGAAGATATTATTTACTCATTACCTCAACTTGAAGAACTTAATGCTACTTCAATTAAAAATCCAAATGTAACAAAAGAAACTAAGAACATTAATGACTTCATGGTACTAAACTTAAATTATTTAGGCCAAATGACAATGCTCACTGAGTTAAGACTAAAAGGTTTAAGTGGAATAAAATTAACGTCATTGCCATCTTTTGGAAATTTAGTTAATTTGAATAAACTTTCATTGACTTCTATTAAATCATTTCCAAAAGACATCTGTCAGAGTTTGGAAACTATTACTGATAACCTAGAGTTTTTTGAAATTGGTGATTGTGATTGTTTATCACCAGAGTTTGCATCGCCATTAAAAAGATTTGTTAATTTGAAATCATTGAGATTAGAAAACTGTGGTCGATGGGAAAGTTGTGCACAAGATGTTTTTCCTGTTATTAGGAGTCTTGAAAAGCTTACTATTCTGGAATTGGTAAACATAGAATTTAGTAGTGTTGTCGAAGATGAATTGGAAAAATGTGTTGGTATTAAAGCTTTACTGATTATTCCTGCCTATGTGAGCCAATCTGCAACTACCAATTGCCACTTGATTGACTGTCTCAAAAAACTCTCCAAGAATTTAACACATTTGGTTTGGGGATTGACTCATGAATTACTCCGTGTTACAGACTTATTTATAACTCAGTATCAACAGAACCAGCATAGTATTGGTTACAATTTAGAATTATCCCATGCCAGAGAACAAACCAACAATATACCTATATTGAGGACAAGAAAACCCAAACAGCGGCCAGATGTGGTTGCTTCAGAAAATGATAAGGAAAAAGACAAATCAGATAACGTTGATATACTTTCAGTTCCTGCTCTAGAGAAATTATTGGATACAATGATGCCTGATGCTAAAACTAGAGTACTTAAGGTTCCTTTTTCGGGAACAGTTAGAGTTTATTTGAGCGAACAGTTTAATGATCTTTGA
Protein Sequence
MDKSERKKSAGLKETNNLLNLEAHFLGFDIDDEVLIVIENKKKSLKMELSKETGEPMEVDDPTDSPSIVNNNHVNKKKKSKSSISSPEPSDVKNSRSNKRQKKDNKNNDASESLELDVTPPLELTTPTFNLTSSNTRSRRSTGRKMNVDISDALFKLPFEFGWKRELVYRTSGESTIINRGNRSGDVYYYSPNNRKLRSLREIQEQLDADSENVLTIDSFTFLKQPIGMNDRSKELIRDANSKLSKEDSFIAIRPKKSKTPVQQRPPFDYELSDDENNKSSSKMKIVFKSGKTPRSRSKKVNSESMNTSSSTPEYIAEDWQAIQSSVSPKVFSPKLENNDINTSTTKRRSSTSDGEVIMQTPCGIRCPNSDEPATLMCAQCLVYYHPACVNLNANLKIVGYVCINCRSTVRQRNRRVQSSHTVVVGATEPEQLRVEPIRIRQVHQASDTPNFFIDRTPISKIEESHYEIDEYSDESESDIINTVICQGNEYKTTMVDGNFHEQYVYEMKQTRGPSLMTCVIQEPNNLDENSEMNGSLRDIATSSTSTSMQSFNYMAKALRHVFKYLKTHELLSASRVCTAWHIIAMNKFLWQNVRLKNSMVYDWERFVNTIEQQLTHTLDTRRMLIPSKVEEFEDFWLNFSKAMKRAQKLKLIELYRCPTHVVEDIIYSLPQLEELNATSIKNPNVTKETKNINDFMVLNLNYLGQMTMLTELRLKGLSGIKLTSLPSFGNLVNLNKLSLTSIKSFPKDICQSLETITDNLEFFEIGDCDCLSPEFASPLKRFVNLKSLRLENCGRWESCAQDVFPVIRSLEKLTILELVNIEFSSVVEDELEKCVGIKALLIIPAYVSQSATTNCHLIDCLKKLSKNLTHLVWGLTHELLRVTDLFITQYQQNQHSIGYNLELSHAREQTNNIPILRTRKPKQRPDVVASENDKEKDKSDNVDILSVPALEKLLDTMMPDAKTRVLKVPFSGTVRVYLSEQFNDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00940496;
90% Identity
iTF_00134270;
80% Identity
-