Apic018410.1
Basic Information
- Insect
- Aphaenogaster picea
- Gene Symbol
- -
- Assembly
- GCA_003063865.1
- Location
- NJRM01000067.1:6252-10141[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.013 1.4 10.0 0.4 1 20 62 81 62 82 0.95 2 19 0.0013 0.15 13.0 0.7 1 21 100 120 100 121 0.94 3 19 0.0033 0.37 11.8 1.1 2 23 180 201 179 201 0.94 4 19 0.00039 0.044 14.7 2.3 1 23 205 227 205 227 0.97 5 19 2.2e-05 0.0025 18.6 0.6 3 23 235 255 234 255 0.97 6 19 2.7e-05 0.003 18.4 4.5 2 23 262 283 261 283 0.96 7 19 1.9 2.1e+02 3.1 4.4 1 23 292 314 292 314 0.90 8 19 0.21 23 6.1 0.2 3 23 322 341 321 341 0.94 9 19 0.67 75 4.5 0.4 3 11 349 357 348 360 0.89 10 19 0.54 60 4.8 0.8 1 22 444 465 444 466 0.72 11 19 2.1e-05 0.0024 18.7 1.1 3 23 476 497 475 497 0.96 12 19 1.9e-05 0.0021 18.8 3.2 1 23 503 525 503 525 0.98 13 19 0.055 6.2 7.9 0.4 1 23 529 551 529 551 0.97 14 19 1.2e-05 0.0013 19.5 1.5 2 23 558 579 557 579 0.96 15 19 7.8e-06 0.00087 20.1 0.2 1 23 585 607 585 607 0.98 16 19 0.045 5.1 8.2 0.7 1 23 613 635 613 635 0.97 17 19 7.1e-07 7.9e-05 23.3 0.2 2 23 642 663 641 663 0.97 18 19 6.5e-07 7.4e-05 23.4 0.6 1 23 669 691 669 691 0.98 19 19 1.2e-07 1.3e-05 25.8 1.9 1 23 697 719 697 719 0.99
Sequence Information
- Coding Sequence
- ATGAAGTATCTGATTCGATGTGTCACTGAGATCGCAGCTCTGAAATTGTACAGTAAAACTAAAAAATGGAATTCGAGGACACGTCAGAAAAAACCTTTGGTGAAAAAGGAACATCAAGGTGCATCTTTCGTTATCCTCCAAAAGATCGACGACGAAACTGTTCTTGTTCAAGAGGTAACCACGTACCACTGTGATTCATGTAACGAAGATTTTGATACAAAAGCCAGTTTGATAGTTCATAAAACAGAACAATCGATACTTAGAACCAGAGAAGCGTTGCGTCAAGCAAAAAAGAAACACGAGTGTGACATATGCAGACAGACGTTTTCGAAAATGTTTGAATTGATCAAGCATCGCCAAATACAATGTAGGTATCCTCTGGCCGCTGAAAAGAAGCAGGTACAGAATAAAAACGTTACAGTCGTGCACCCAAAGTTACCCCCCTTACCCAtcgggaaagacgtagttctacgtcaaaaagttacaaaaattaaGAGAAGTCGAAAGGAGAACGAGGAATCGTCAGCAGGTCCCATTGAATGTGATCAGTGTTACAAGGTATTCAAGAAGAAAAGGTATTTGGACGTGCACAAAACGTTACATGGTGCTCCGCATATTTGTCATATATGTGGCGCGAAGTTGACATCGgattattatctaaaaattcaCATCAGGCGGCACAATAAGGAGTTCACGGAGTTTTGCGAGATTTGTAACAAAGGGTTCTACTTGAAGGCAAATTTGAAGACTCACATGAGCGTGCACACCGACGAAAAGCCCTGTACTTGCGAGATCTGCCACAAGTCCTTCGGCAATCGAATCTACCTTCGAAGTCACATGAAGATTCACATTCAGCCCGAGACGAGGAAGAAATATAAGTGTGAAATATGCAGCTTTGAAACATTCTATAACTATTGCTATAAGGAGCATATGTGGACTCATACAGGCGAGAACCAAGTGGCATGCGAAGTATGTGGCAAGCTAATTAGTCGGCAGTACATGAAGACTCATATTAGGATACACACGGGCGAGAAACCGGAGATTTGTGAGTTTTGTGGCAAGGCGTTCAGTGCCAGGAAgtGCGAGGAGATCGACATAGAAGATGTAAAGCTGGACTCGATCGACGAATTGCAAGGTATAGAATTAGTACAATATCAAAACGACGTATCTACAGTGGAAGAGTATGATCACGTCGGTCATCAAGAAATTGTTATGGAAACGATCGAATATAAGACCGAAGATTCAAGCGACAAACTAGTATCTGCGTCGGACATACGTGTTATAAAACGGGTTTCCGGACACGATCCGAGTCGTAAGCGTGCGACGGTTTACGAGTGTGAAATTTGTGGGAAGCAAATGCTCAAAAAGCTGCAGTTTTTGAAGCATAGACAAGACCACGAGAGGAATCCGAAGACCGAAGGTCATTGCGAGGAGTGCGACAAAATCTTCGACAATGAGGAGAAGTTGCGAAAGCATATGATAAAAGCACACCAGAAGGAGAAACCTTTTCAATGCGTTCTGTGCGGCAAGTGTTTCAAGACCGAGGAGTTCTTGAAGATCCACTTGAAGCAACACAACAAACGTTTCACCTGCGACATATGCGGCGTATCGAAGGTCTCCGGATATGATCTGCGTTTGCACAAGAAGAAGCACAACCAGGAATATGTGATTCATTGTGAGATTTGCAACAAAGGCTTTTACACGAATCAGACGCTGGAGCGGCATTTGCTTACACATACTGGTGAGAAGCCGTTTGTGTGTAAAGTATGTAACACTGCGTACGCGAGTGCAGCGTATCTCAACATGCATATGAGGTCTCATGGCGAGAGGGAGAAACACAAGTGCAATATCTGCGATTTCGAGAGCTACTGGAAGGCCGCGCTAAAAGTGCATCTTAAGATACACACCGGCGAGAATCAGATCACGTGCGAGGTGTGCGGGAAGTCCGTAAGCAGCAAGACGTACCTGCAAATTCACATGCGTATACACTCGGGCGAGAAACCACACGTTTGCGAGGTATGCGGCAAGGCGTTCAGTGTACGGAAGTACCTAATCGTGCATTTAAGAACACATACCGGCGAGAGACCTTACGAATGTAAAGTGTGTCAGAAAAGATTTACGCAACAGGGCTCACTAAACTCGCATATGAAGTCTCATAATGAGTGCAAGTGA
- Protein Sequence
- MKYLIRCVTEIAALKLYSKTKKWNSRTRQKKPLVKKEHQGASFVILQKIDDETVLVQEVTTYHCDSCNEDFDTKASLIVHKTEQSILRTREALRQAKKKHECDICRQTFSKMFELIKHRQIQCRYPLAAEKKQVQNKNVTVVHPKLPPLPIGKDVVLRQKVTKIKRSRKENEESSAGPIECDQCYKVFKKKRYLDVHKTLHGAPHICHICGAKLTSDYYLKIHIRRHNKEFTEFCEICNKGFYLKANLKTHMSVHTDEKPCTCEICHKSFGNRIYLRSHMKIHIQPETRKKYKCEICSFETFYNYCYKEHMWTHTGENQVACEVCGKLISRQYMKTHIRIHTGEKPEICEFCGKAFSARKCEEIDIEDVKLDSIDELQGIELVQYQNDVSTVEEYDHVGHQEIVMETIEYKTEDSSDKLVSASDIRVIKRVSGHDPSRKRATVYECEICGKQMLKKLQFLKHRQDHERNPKTEGHCEECDKIFDNEEKLRKHMIKAHQKEKPFQCVLCGKCFKTEEFLKIHLKQHNKRFTCDICGVSKVSGYDLRLHKKKHNQEYVIHCEICNKGFYTNQTLERHLLTHTGEKPFVCKVCNTAYASAAYLNMHMRSHGEREKHKCNICDFESYWKAALKVHLKIHTGENQITCEVCGKSVSSKTYLQIHMRIHSGEKPHVCEVCGKAFSVRKYLIVHLRTHTGERPYECKVCQKRFTQQGSLNSHMKSHNECK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01422378;
- 90% Identity
- iTF_00129919;
- 80% Identity
- -