Amia024293.1
Basic Information
- Insect
- Aphaenogaster miamiana
- Gene Symbol
- bab1
- Assembly
- GCA_003063725.1
- Location
- NJRN01000017.1:1135262-1137460[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 2.4e-23 9.3e-21 74.5 0.2 1 83 35 114 35 126 0.89
Sequence Information
- Coding Sequence
- ATGGAGACAGATCGTTATTGGGGCGTGCACTACAGCGGCGGTATGGCCGGGCAGCACTACTGCCTGCGCTGGAACAACTACCAGTCGAATATGACGTCGGTGTTCCACCAGCTCCTCCAGACCGAGGCTTTCGTCGACGTCACCCTGGCATGCAACGAGGCCTCGTTAAAGGCGCACAAGGTGGTGCTGTCGGCTTGCAGCTCCTACTTCCAGAAGCTCCTGCTGTCGAACCCCTGCAAACACCCGACGATCATCATGCCGCAGGACGTCTGCTTCAACGACCTCAAGTTCATCATCGAGTTCGTCTACCGCGGCGAGATCGACGTTTCGCAAGCGGAGCTTCAGCTTAAAGTGCCTTCAATCCTAGTTCTAGGATTTTTTATCACGCCTCTGGAATTCGTACACCggtga
- Protein Sequence
- METDRYWGVHYSGGMAGQHYCLRWNNYQSNMTSVFHQLLQTEAFVDVTLACNEASLKAHKVVLSACSSYFQKLLLSNPCKHPTIIMPQDVCFNDLKFIIEFVYRGEIDVSQAELQLKVPSILVLGFFITPLEFVHR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00962613; iTF_00866114; iTF_01233763; iTF_00863368; iTF_00864744; iTF_00866800; iTF_00862680; iTF_00860505; iTF_00861278; iTF_01539715; iTF_01049060; iTF_00184038; iTF_01475590; iTF_00255209; iTF_01395241; iTF_00252946; iTF_01423783; iTF_00867560; iTF_00873893; iTF_00392870; iTF_01268399; iTF_01234448; iTF_01271344; iTF_01111955; iTF_01514260; iTF_01469850; iTF_01111131; iTF_01269915; iTF_00868989; iTF_01466397; iTF_00868224; iTF_01380730; iTF_00714542; iTF_00713778; iTF_00713049; iTF_01381467; iTF_01354728; iTF_01417801; iTF_00393707; iTF_00881419; iTF_00961931; iTF_00963297; iTF_00691278; iTF_00286576; iTF_00088945; iTF_00140691; iTF_00633747; iTF_00127604; iTF_00126852; iTF_00460948; iTF_00905537; iTF_01465507; iTF_00721388; iTF_01364785; iTF_00058839; iTF_00168634; iTF_00143995; iTF_00058076; iTF_00109942; iTF_00126105; iTF_00982393; iTF_01245338; iTF_00729454; iTF_00080411; iTF_00983067; iTF_01473307; iTF_00225342; iTF_01392158; iTF_00264415; iTF_01254924; iTF_00360319; iTF_00762655; iTF_01389600;
- 90% Identity
- iTF_00080411;
- 80% Identity
- -