Aflo012069.1
Basic Information
- Insect
- Aphaenogaster floridana
- Gene Symbol
- bab1
- Assembly
- GCA_003063835.1
- Location
- NJRP01000451.1:46555-48100[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 2.1e-23 7.5e-21 74.8 0.1 1 84 35 115 35 124 0.91
Sequence Information
- Coding Sequence
- ATGGAGACAGATCGTTATTGGGGCGTGCACTACAGCGGCGGTATGGCCGGGCAGCACTACTGCCTGCGCTGGAACAACTACCAGTCGAATATGACGTCGGTGTTCCACCAGCTCCTCCAGACCGAGGCTTTCGTCGACGTCACCCTGGCATGCAACGAGGCCTCGTTAAAGGCGCACAAGGTGGTGCTGTCGGCTTGCAGCTCCTACTTCCAGAAGCTCCTGCTGTCGAACCCCTGCAAACACCCGACGATCATCATGCCGCAGGACGTCTGCTTCAACGACCTCAAGTTCATCATCGAGTTCGTCTACCGCGGCGAGATCGACGTTTCGCAAGCGGAGCTTCAGCCCGATATCCTCGGCATTCTTGTACGGAAATTTTTAGGAATGTGA
- Protein Sequence
- METDRYWGVHYSGGMAGQHYCLRWNNYQSNMTSVFHQLLQTEAFVDVTLACNEASLKAHKVVLSACSSYFQKLLLSNPCKHPTIIMPQDVCFNDLKFIIEFVYRGEIDVSQAELQPDILGILVRKFLGM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00128356;
- 90% Identity
- iTF_00127604; iTF_00126105; iTF_01233763; iTF_01234448; iTF_01267683; iTF_01254924; iTF_00729454; iTF_01268399; iTF_01271344; iTF_01245338; iTF_01269915; iTF_00264415; iTF_01465507; iTF_01049060; iTF_00878182; iTF_00882310; iTF_00368204; iTF_00708625; iTF_01469850; iTF_01468155; iTF_01466397; iTF_00873893; iTF_01130949; iTF_00252199; iTF_01198795; iTF_01474067; iTF_00296155; iTF_00297693; iTF_00863368; iTF_00184038; iTF_01354728; iTF_01417801; iTF_00393707; iTF_00691278; iTF_00866800; iTF_00088945; iTF_00306386; iTF_00713778; iTF_00140691; iTF_00633747; iTF_01306644; iTF_01514260; iTF_00109942; iTF_00713049; iTF_01539715; iTF_00714542; iTF_01111955; iTF_01111131; iTF_00860505; iTF_00864744; iTF_00861278; iTF_00982393; iTF_00143995; iTF_00983067; iTF_01381467; iTF_01380730; iTF_01380093; iTF_01473307; iTF_00868989; iTF_01392158; iTF_00360319; iTF_01389600;
- 80% Identity
- iTF_00983067;