Basic Information

Gene Symbol
ZNF236
Assembly
GCA_003063765.1
Location
NJRO01000182.1:75618-79474[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00067 0.08 13.8 8.6 1 23 14 36 14 36 0.98
2 11 0.44 52 5.0 2.0 2 23 392 413 391 413 0.92
3 11 6.3e-06 0.00076 20.2 2.6 1 23 419 441 419 441 0.99
4 11 2.8 3.3e+02 2.4 1.1 2 23 448 469 447 469 0.90
5 11 1.5e-08 1.8e-06 28.4 1.4 2 23 543 564 542 564 0.98
6 11 0.00012 0.015 16.1 5.0 1 23 570 592 570 592 0.99
7 11 0.00016 0.019 15.8 4.0 1 23 598 620 598 620 0.97
8 11 1.8e-05 0.0022 18.8 2.6 1 23 626 648 626 648 0.98
9 11 6.6e-06 0.00079 20.1 0.7 2 23 885 906 884 906 0.97
10 11 3.4e-06 0.00041 21.0 4.2 1 23 912 934 912 934 0.98
11 11 0.0011 0.13 13.2 8.3 1 23 940 963 940 963 0.98

Sequence Information

Coding Sequence
ATGAAGAGGCACTTAGTCACGCATAGCAATAAAAGGCCCTATATGTGTCCGTACTGCCACAAGACGTTTAAGACGTACGTCAGTTGCCGGAAGCACATGAAAAGGCACAAGCACGAGCTGGCGCAACGGCAATTGGAGGAACAAAAGATGCAGGATCAGAAAGAACCACAGCCTTTAAGCGAGGATAAAGGAGTTACCTCAGCGTTACCGGAGAGCATCACCCTCACCGAAGATATGGAGGTGTCGTTCCAACCGCAAATGGCGCCAGATTTTACGCAGGCTTTCTCCGATCAGTTTCAAAATATCAGCGCGGAGAAAGAGAAATCTTTCTTATTGTCCGACAACGCAACGCCATCGATAGTGAATCAAAATTTATCTGTCGACACAACTAATTTAGGAACGTCGCAAACTCTACACGCTGATGAAACCGGTACTATCACGTTACCTCATTACTCAGGGGATCAAACTCTCACGCCgGAAAGCATACGAGAAATCGAGGAGACTCTGAATCAGCAACTGTTTAATATCGGCATGAATCTCGGACTAGGAGCAAACAATCTACCGAGGCAAATGGACGAGGCGAATACGAATTCTCTCGACAATTCCAGGGAACAACCGGTgctcaatattatatatgagcaTAACAAGACTCTGGAATCGGCAGGCAATACCATATTCATGTCGCAATTCGATTCGTTTGATATGAACCAAATCACATTACAGACGGATAACGATATAGATATCGGTTTAAATCCGAGCAATTCCACGAGTATGTCTAGTATTTTGCCCAGATCCGTAGGAAGCAACCCACAAGAGGAACAACGAGCTGCTCCAATTACTACCGCCAGCAATATAGACGCTTCTCAAATTACGAGAAACACTCATCTCGTAGTAATAAATCCTAAGGAGAATTGTTCAGAATTGGTGAGACTCTCGCAAGTATGCCCGTCAAAGTACTCGAAAGTTATTGCGAAGGCGGACACCACAAATGGATTGGAGATGCAAAGTGTGAGTGAACACGAAAAGGCACCACAAAAAAGTAACGCTATGTCATGCAAGAACGAAAGAAATCCTTTGTTCATGAAGAATTTCCAAAGTACAATGCAATCGGAGACGCTCGTTTCTTCTGGCATGGACAGCTCGACTAAAATATTGGAGAGTAATACTCTGTTGCAGTGCCACATGTGCGGTAATCAAGGTTTCACGACTGAAAGATTGAAGGAACACCTGAAATCTCATCGCGGTTCCAAAGAGTACGAGTGTTCGGAGTGTTCCCAGCGATTCTGCACAAACGGCGGTCTCAGCAGGCATATGAAGATGCACATGAATAAGCAGCGATGGAAATGCACGACCTGTCAGAAGATACTGGGCAGCAAATTGCAATTGAAATTTCACAGCAAAATACATACTGAGGTTTGGAATGTTTCTTCTATGGAACCCGACAGTTCTCAGAAGGATCTTATTTCCTCGAATTCCAGTCTGCCAACAATGACAACGTTGGATGTCCGAGTACATCCGAACCCATCAGTTTCCGAAAAAGTTTTAATGGATGCAGTCGCCGAGAGAAAAAGCATGGACCACGCTGATGAAAACGTGGAGAAGAAAGAGACAAAGGAATATACTAATAAATGCAAATACTGTCCGAAAACTTTCCGCAAACCAAGCGACCTCATCAGGCACATTCGCACGCATACGGGCGAACGACCGTACAAGTGCGATCATTGCAGCAAGAGCTTCGCAGTCAAATGCACTTTGGATTCGCATATGAAGGTTCATACGGGTAAGAAGACATTCTGCTGCCACGTCTGCAGCAGCATGTTCGCTACAAAAGGCAGTTTGAAGGTTCACATGCGATTGCATACGGGTTCGAAGCCGTTCAAATGTCCCGTGTGCGATCTCCGATTCCGCACTTCGGGTCACAAGAAGGTGCACATGCTGAAACACGTGAGAGAGTATAAAGGCGGCACGAAGCGCAAACCGAAACACTCGAAGATCGCTGCAGTAGCGGAAGCGGCGGCCAGCCTCGAAAAAATCGGCAAAAATTCCCTGGAAAATGCATCGATGACGATGACAACGGCGACGGCTATGATCAACGACGAGACCGGGCCATCGCAAAATCTGGATTATCCCGCGTTGGAACAGACAGTGAATCTCGATACCACGGTTCACTTGCCGAATCAAATCGCGTTCAACCATActgacgcgacgacgacgattctCAACAACAATTCTATGCTGTCCGTGAACGAGAACAATGAGCTGGTGGCGAATCTGCAGTTCTTGCTGGCGAACGGTCTCGTCACTATTCAAACGGACGACACGCTACTGACACAGCCAGTGGCAAACAGTTCCGATGCCACCGAAGTGCCAACTAACATGATCGAGTTAGTCAATCCAGATCCTTTCCAAGAAGCTTGCAACCTGGGTAACGCTAATCACGTGATGATAACCAGCCAGGTGCCGACAGAGACGACAACCGCGGACACGAGCAACGCGACAGTTATTCAAATGAATAATTGTGTGCCCCCAGTGTCCATGGTACAGATGCAAACTCAAGATGCAAACGGCGCCGGCGTATCTGAAACGAAGATGAGCGATCAAATGAcaacaacgacggcgacggcgaaaACTTCGACGCAGCCTTCAAGGAAAGAGTGCGATATATGCGGCAAAACGTTTATGAAGCCCTATCAAATGGAACGACACAAGCGTATTCATACGGGGGAACGGCCGTACAAGTGCGAGCAATGCGGCAAGTCGTTCGCGCAAAAATTTACGCTGCAGCTGCATCAGAAGCACCACACCGGTGACCGGCCGTACTCCTGTCCGCACTGCAAGCACTTGTTCACGCAGAAGTGCAACCTGCAGACGCATCTGAAACGTGTCCATGAAGTGGTCATGCTCGACGTCAAGAAGCTGAAAAGCGGCCAGCAAATGCTGGGCGCGCTTCTACAGGACAATCAAGGCGGTGATACTAAGCTGCTAAACTTGGACGACATATTGGTggtagatttttttaaatga
Protein Sequence
MKRHLVTHSNKRPYMCPYCHKTFKTYVSCRKHMKRHKHELAQRQLEEQKMQDQKEPQPLSEDKGVTSALPESITLTEDMEVSFQPQMAPDFTQAFSDQFQNISAEKEKSFLLSDNATPSIVNQNLSVDTTNLGTSQTLHADETGTITLPHYSGDQTLTPESIREIEETLNQQLFNIGMNLGLGANNLPRQMDEANTNSLDNSREQPVLNIIYEHNKTLESAGNTIFMSQFDSFDMNQITLQTDNDIDIGLNPSNSTSMSSILPRSVGSNPQEEQRAAPITTASNIDASQITRNTHLVVINPKENCSELVRLSQVCPSKYSKVIAKADTTNGLEMQSVSEHEKAPQKSNAMSCKNERNPLFMKNFQSTMQSETLVSSGMDSSTKILESNTLLQCHMCGNQGFTTERLKEHLKSHRGSKEYECSECSQRFCTNGGLSRHMKMHMNKQRWKCTTCQKILGSKLQLKFHSKIHTEVWNVSSMEPDSSQKDLISSNSSLPTMTTLDVRVHPNPSVSEKVLMDAVAERKSMDHADENVEKKETKEYTNKCKYCPKTFRKPSDLIRHIRTHTGERPYKCDHCSKSFAVKCTLDSHMKVHTGKKTFCCHVCSSMFATKGSLKVHMRLHTGSKPFKCPVCDLRFRTSGHKKVHMLKHVREYKGGTKRKPKHSKIAAVAEAAASLEKIGKNSLENASMTMTTATAMINDETGPSQNLDYPALEQTVNLDTTVHLPNQIAFNHTDATTTILNNNSMLSVNENNELVANLQFLLANGLVTIQTDDTLLTQPVANSSDATEVPTNMIELVNPDPFQEACNLGNANHVMITSQVPTETTTADTSNATVIQMNNCVPPVSMVQMQTQDANGAGVSETKMSDQMTTTTATAKTSTQPSRKECDICGKTFMKPYQMERHKRIHTGERPYKCEQCGKSFAQKFTLQLHQKHHTGDRPYSCPHCKHLFTQKCNLQTHLKRVHEVVMLDVKKLKSGQQMLGALLQDNQGGDTKLLNLDDILVVDFFK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
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