Aepo022712.1
Basic Information
- Insect
- Apamea epomidion
- Gene Symbol
- Znf131
- Assembly
- GCA_947507525.1
- Location
- OX382254.1:9534434-9537964[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.4e-06 0.0001 23.0 1.3 1 21 108 128 108 129 0.94 2 17 0.18 13 6.9 0.3 1 22 160 181 160 183 0.85 3 17 0.0067 0.47 11.4 3.4 1 23 188 210 188 210 0.96 4 17 2.1 1.5e+02 3.5 5.5 1 22 213 234 213 234 0.95 5 17 4.7e-05 0.0033 18.2 1.1 1 23 248 271 248 271 0.95 6 17 4.2e-05 0.003 18.3 1.7 1 23 277 299 277 299 0.98 7 17 1.3 92 4.2 2.8 1 23 333 356 333 356 0.90 8 17 0.0011 0.075 13.9 0.7 2 22 483 503 482 506 0.89 9 17 0.26 19 6.4 0.1 3 23 510 531 509 531 0.95 10 17 0.021 1.5 9.8 1.7 1 23 536 559 536 559 0.94 11 17 0.0013 0.092 13.6 1.3 2 23 565 586 564 586 0.94 12 17 0.9 64 4.7 1.2 2 20 590 608 590 610 0.91 13 17 2.8e-06 0.0002 22.0 1.2 1 23 636 659 636 659 0.95 14 17 0.0002 0.014 16.2 0.5 1 23 665 687 665 687 0.95 15 17 0.063 4.5 8.3 0.1 1 23 693 715 693 715 0.97 16 17 0.0033 0.23 12.3 0.3 1 23 721 744 721 744 0.94 17 17 0.0001 0.0071 17.1 0.8 2 23 751 773 750 773 0.95
Sequence Information
- Coding Sequence
- ATGGAGTTGGACCCCGCGCTCCCCTGCGGCTTATGCCGGAGCTGTTCCGACGACACCCTCGCAGCCATTACCTTCAAGAACCTCTGTGCACTGTCGGCACACCATTGGGCAGAAGGATCCAACTACATCTCCCATCCCCCAACTCCCACTGAAGATGACAAAGCCTATTTCATTCTCTATAACGACGAAAAAACCATAGTGAAAGACCAAATCGCCAGAGTTCCTACCACAAAGGATGCTGTGGACAGGTTAAATATGAAGTGGGTTAAACCAGTGAAAACGCGGAAGCCTCGACGTCCGCAAGCCTTGATTAAAGAATCGTGCAAGTGTCCTGATTGTGGCAAGAAATTCTCGACGCCAGATTATTTGAACTACCATCTAAGAAACACGCTTACGCGAGCCTGTCGTAGATGTCGAATGGTCATTCACAAGAAAAAATTGGCCAAGCATTTGTCTAAGAATCATAACGTACACGTATTTGAATGTAATGTTTGTAACAAATTGTTTGATGAAGAACAGTTCATGAAGCAGCATGTCGATGAGGCTCACGGCAAACTTATGCACTCTTGCAGTCACTGTGGTAATAGTTATGTTAACGAAAGAGCCCTGAGAGCTCACGCGCATTCTCACTCGCTGTTCCACTGCAGCTCCTGCAACATGAGCTTCGACAGCGTTAAATGTTTCAAATACCATCAGCAAACATGCGAATACTTGCACCGGCCATTAGTCGAGTTCAAATTCTTTACTTGCGATCACTGTGGCGTGACTTACAACCGGAAACCGTCCCTCAGAATACATATCATCCAAAAACATCTTAACATTCTGCCTTACGTTTGCCAAACATGCGGAAAACGGACTTCCACATTAGCTCATTTGCGGTCTCACGAAAAGGTGCATAAAACTGAGCGAAAGGTCTTCCAGTGCTGTTGTGGGGCTCAGCTGACCACAGAGTTAGGCTTCCAGTTACACCAGAGAATCCACACTGGGGAACGACCATACAAATGTGAACATTGTGGAGACAGATTCCTCTCTTCTTCAAGGAGACTCGATCATATAAAAAGACGTCACAGAGGGACAAAGGATTTAAAACACGGCTGCGAGCAGTGTGCCGCTCGCTTTATGAAAGAAGAATCCCTAATACCAGTAGGTGCGTGTGTTGCCTGCGCCAGCACAGCCCTCGCCGCACAAGAATTCCGCCTCTTTGTCAGGAACTCAGAAAAACTATGGCGGAAAGCTCTCATCAACATTGCTACCTTGCCAAACTCAGTATTTGCCCCGTCCGTCAAATCAGTCTGCGCATTCATCAAAACATCTGACCTCTCGATACAGACGTTCAAAGACTACAACACTAGCGACGCCAAAACGATCCTAAATCGATTAAAAAATCGAGTCACGAAAAAACCTGTCGAGAGGAAGCCTAGAGGGGCACGCACTGGACCGTCTTGCAGTTGTCCTGATTGTGGAAAGGGCTTCCTTAGTCCGTACTACCTAAATATGCATTTAAAAAATAGTGGGCATAAGGAGGCCTGCCTCCTTTGTGGTTCAGTCTTTGTTAGAGGGAAAGAAATGCAGGAACATCTGTCTTCTGTTCACAATGAGATTGTATTCCTGTGTAAAAAGTGTCCCATCTTATGCCCAAATGAAACACAGTTGAAAAAACACGTCAAAAAGGCCCACAAAGCTGGGGCGTTGACTTGCACAGATTGTGGCAGGACCTTCCCTAGAAACGCTTCCTTTGAGTGTCATGCACAAATGCACGCAGTCAGGACTTGCCGTGCTTGTGGAGTACAGTTTACCAACCGAGGGTGTTATAGAGAACATAGGTCACAGTGTGAACCAGATGCTAAGCCTAATGCTCAAGATGTACCTAGAAATCGACGCTCCAACATCCGCGACCCTGCGACCTTCACTTGTGACCATTGTGGCAAAACATACAACTCTAGACCCCAACTCAAAAACCACATCCTCTGGATTCACATGGATATACGACCTCATCAGTGTACGTGGTGCGGAAAAAGGTTTTACACCCCTGCACGACTGGCCGAACATACTGTAGTCCATACCCGCGTTCGAAATTTCGAATGCGACATTTGTGGCGCGAAACTCGTTTCGAAAATGGCCGCCGTATACCATAGACGAAGGCATACGGGTGAGAGGCCGTATGAATGTGAAGATTGTGGGGAAAAGTTTATTTCTGCTTCTCGTAGATCGGAGCATGCCAAGCGTAGACACAATAAAGGGTACAGGCTGCCTTGTCTGAAATGCCCTGCGAATTTTGTTAGGAAACATGAGTTGAAAAAGCATATGGAAAAGGCACATAAAGGGCCAGAGAATTCTCTGGGTTGGCCACAATGA
- Protein Sequence
- MELDPALPCGLCRSCSDDTLAAITFKNLCALSAHHWAEGSNYISHPPTPTEDDKAYFILYNDEKTIVKDQIARVPTTKDAVDRLNMKWVKPVKTRKPRRPQALIKESCKCPDCGKKFSTPDYLNYHLRNTLTRACRRCRMVIHKKKLAKHLSKNHNVHVFECNVCNKLFDEEQFMKQHVDEAHGKLMHSCSHCGNSYVNERALRAHAHSHSLFHCSSCNMSFDSVKCFKYHQQTCEYLHRPLVEFKFFTCDHCGVTYNRKPSLRIHIIQKHLNILPYVCQTCGKRTSTLAHLRSHEKVHKTERKVFQCCCGAQLTTELGFQLHQRIHTGERPYKCEHCGDRFLSSSRRLDHIKRRHRGTKDLKHGCEQCAARFMKEESLIPVGACVACASTALAAQEFRLFVRNSEKLWRKALINIATLPNSVFAPSVKSVCAFIKTSDLSIQTFKDYNTSDAKTILNRLKNRVTKKPVERKPRGARTGPSCSCPDCGKGFLSPYYLNMHLKNSGHKEACLLCGSVFVRGKEMQEHLSSVHNEIVFLCKKCPILCPNETQLKKHVKKAHKAGALTCTDCGRTFPRNASFECHAQMHAVRTCRACGVQFTNRGCYREHRSQCEPDAKPNAQDVPRNRRSNIRDPATFTCDHCGKTYNSRPQLKNHILWIHMDIRPHQCTWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGERPYECEDCGEKFISASRRSEHAKRRHNKGYRLPCLKCPANFVRKHELKKHMEKAHKGPENSLGWPQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00274608;
- 90% Identity
- iTF_01527597;
- 80% Identity
- -