Ader003646.1
Basic Information
- Insect
- Anticlea derivata
- Gene Symbol
- Rfx2
- Assembly
- GCA_947579855.1
- Location
- OX388262.1:12523677-12543117[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.2e-37 2.1e-33 114.9 0.0 3 78 120 195 118 196 0.97 2 2 0.8 7.9e+03 -2.3 0.0 24 32 534 542 517 551 0.68
Sequence Information
- Coding Sequence
- ATGTCGGATGCTGTGTTGCTCCGGAAGCCAAGGCGAGTTGCCTGGGAGACCTCGGCCGCTATGGAGGTGCCTCGCTACCGTCCTTACTACCCCTGTGAGGGAGGGAATGGCGTTAACTATCATGTGCAGTATGTCACCGAGCCGCAAGAAATATACACGCAAGGACATCAGGCTATGGAGACACTCCGTTCGTACCCAGTGTACGGCGTGACGACTGTCGGCGGCGCGGCGAGCGAGGCGGACGCGGCGTGGGGCGGCGCCTCCAATGCCGACTACACCGCCTATGGCGTCGTGGTGGCAGGCGAGGAGGTGGAGGCGCCCGCGTCGCCGGCCGGCGCGCCGCCGCGCATGCCGCCCGCCACCGTGCAGTGGCTGCTCGACCACTACGAAACTGCTGAAGGCGTGTCGTTACCCCGGTCGACGCTGTACGCGCACTACCTGCGTCACTGCTCGCTGCACCAGCTGGAGCCGGTGAACGCGGCGTCGTTCGGCAAGCTCATCCGCTCCGTGTTCGTGGGGCTGCGCACGCGCCGCCTGGGCACGCGCGGCAACTCCAAGTACCACTACTACGGCATCCGCGCGCGCCCGAGCCTAGATGCAGCCGCGCACGACGCCCCCGACAGCGCGGACGACAACGCCGACCACAACGACAAGCAGGACGAGAACGACCGCTCCCGCGAGCGTGAAGACGGCTCGGGGTCACCACTTGGAGCCGCCAGCGTCGCTCACAGACAGTACCTGGCGTCTGTCACAGCCCCGTCTCCCCCCGCGCTCGAACTGGACATCTGCGACGACGTGCCGCCCGGAGCGTTGCAACTGCTGCGACGTCGCCATCGTGAACACGGCGCCATGTTCCTGGAGGCGGTGGCGGCGTTGGACACGGGCGCCGTGGAAGCCGCGCGTCGCACCTTCTGGCGGCGCAACTCCTCGGACGACGACGTCTTATGTCGCCGCACCCTGGCTCGCCTATGTTCAAGGAAGGATGTTTGTCGCTGGCTTCGCGCGGCCGACACGCAACTGTACCAGCGTGCCGTCGACATGCTGCTACCAGACGTACTGCGTCCTATCCCACCACAGCTCACACAGGCGATCCGCAACTTCGCGAAGAGCGTGGAGTGCGCGGTGTCGGCGGGGTCGGGCGGCGCGCCGCTGGGCGCCGTGCGGGCGCAGGCGCGCGCCGCCGCCGCGCTCGCCGGGGCGCTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCCGCGCGCGCCGTGCTCACCAACCATCACCAGATACACCAGATGGTATCAGACCTGAACCGTGTGGACTTCCGCGTGGTGCGCGAGCAAGCTTCTTGGGCCTGTGCTTGTCCCTCGGCCTCCGTGGCGCTGAAACTTGAAGCTGACTTCAAGGCGACGCTGGGGCGCGGCGCGAGCCTGGAGCAGTGGGCGGGGTGGCTGGAGCGCTGCGTGGGCGGGGCGCTGGGCGCGCACGAGGCGCGCGGGGACTTCGTGCCGCGCGCGCGCCGCCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTCCGCGGCGTCGTTCGGCTCGTTCCACCTGATCCGGCTGCTGTACGACGAGTACGTGTCGTACCTCATCGAGCGCCGCGTCGCCGCGCACCTCGACGCACCGCCCATCGCCGTCATGCACCGCCAGGAGGATGAAGAGGACGAAGAGGGCCAAGAAGAGAACCGCGTCGAAGGCCTGGAAGAGGACCAGGACTGGGACTGGGAGGACGAGGATGATGAAGAAGAACCGGAGAATAAGAAAGCGAAGACCAATGAGTAA
- Protein Sequence
- MSDAVLLRKPRRVAWETSAAMEVPRYRPYYPCEGGNGVNYHVQYVTEPQEIYTQGHQAMETLRSYPVYGVTTVGGAASEADAAWGGASNADYTAYGVVVAGEEVEAPASPAGAPPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCSLHQLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRARPSLDAAAHDAPDSADDNADHNDKQDENDRSREREDGSGSPLGAASVAHRQYLASVTAPSPPALELDICDDVPPGALQLLRRRHREHGAMFLEAVAALDTGAVEAARRTFWRRNSSDDDVLCRRTLARLCSRKDVCRWLRAADTQLYQRAVDMLLPDVLRPIPPQLTQAIRNFAKSVECAVSAGSGGAPLGAVRAQARAAAALAGALRRYTSLNHLAQAARAVLTNHHQIHQMVSDLNRVDFRVVREQASWACACPSASVALKLEADFKATLGRGASLEQWAGWLERCVGGALGAHEARGDFVPRARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVAAHLDAPPIAVMHRQEDEEDEEGQEENRVEGLEEDQDWDWEDEDDEEEPENKKAKTNE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01335664;
- 90% Identity
- -
- 80% Identity
- -