Basic Information

Insect: Anopheles ziemanni
Gene Symbol: Trerf1
Assembly: GCA_943734765.2
Location: OX030920.2:9696433-9741512[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 7.7e-05 0.006 17.1 0.2 2 23 244 265 243 265 0.97

2 6 1.5e-06 0.00012 22.4 1.3 1 23 271 293 271 293 0.99

3 6 0.00012 0.0094 16.4 2.6 1 23 299 323 299 324 0.95

4 6 0.00063 0.049 14.2 0.8 2 23 757 778 756 778 0.97

5 6 0.0012 0.093 13.3 0.3 1 23 1852 1876 1852 1876 0.95

6 6 0.00014 0.011 16.3 0.7 1 23 1909 1931 1909 1931 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	7.7e-05	0.006	17.1	0.2	2	23	244	265	243	265	0.97
2	6	1.5e-06	0.00012	22.4	1.3	1	23	271	293	271	293	0.99
3	6	0.00012	0.0094	16.4	2.6	1	23	299	323	299	324	0.95
4	6	0.00063	0.049	14.2	0.8	2	23	757	778	756	778	0.97
5	6	0.0012	0.093	13.3	0.3	1	23	1852	1876	1852	1876	0.95
6	6	0.00014	0.011	16.3	0.7	1	23	1909	1931	1909	1931	0.98

Sequence Information

Coding Sequence: ATGCTGCTGAACGTTTGCCTCGCCGTCCAGAACAGTATCCGGTTGCCGCTGGCCGGCCTGGCCCCTCCCCGCGTGTTGATGTGCAGTGCCTCGATGGGCGCGGAAGGATCGGTCACGCTACAGCTGCGCGAAGCCGTCCCGGCACCGGATGCGACCGGTTCGCTCGATGGCGCCCTCACGATCGGCTATCCGGACTCGGAGATGCTGGCCGACATGCTCGGCACCTTCCAGGGTGCCTCGACTGGCGGGGCCGACTCCGACGGTGGCAGCTTTGACCTGCTCCAGGACACGGGCCGGACGGCGGCCGAACAGATCGAGCACATCCTCACGAAATCCACCGCTTCCAGCTCGTCCTCGCTAGGCACGAAAGCAGCCACGGAGAAAGCGAATGCAATCACCAACCGCCTGAGCAGCTCGTCCAGCACCAGCTCGTCGccttcgtcatcgtcgtcgtcgttgtcgggcGTTCTGCATCACGGCACCACGATGGTGACCGTGAAAAGTGCCGCCAGTGGCAGCAGCCCCAGCGCCAGCATTGCCGCGGCCAGCCccaccgcctccaccaccagcctTGTCCTGACGGCCGTCGGTCGCAGCGAGACGATTTCGCCGGCGATGGCTTCCGGCAACAGCTCGGCGGCCTCGTCACCGTCGGCCGCCTCCTCGCCCGGCGGGCTGGCGAAGAAACCCCGGCCCAAGACGGTCTCACCGACCCGGCACGGGCCGCAGCAGTGTCAGGTCTGCAGCAAAGTGTTCGGGAACGCGTCCGCCCTGGCCAAGCACAAGCTGACGCACAGCGACGAGCGGAAGTACGTGTGCGGCATGTGCTCGAAGGCGTTCAAGCGGCAGGATCACCTCAACGGCCACATGCTGACGCACCGCAACAAAAAGCCGTACGAGTGCAAGGCGGACGGATGCGGCAAGTCGTACTGCGATGCGCGATCCCTGCGGCGTCACACGGAAAATCATCACACGGCGCTCGGCCTGGCGGGTGGCGCTTCCGGCACGGCCAGCCCCGGCCCCGGCGGAGGCAGCAATGCCGGGCCACCCGGGGGGCTCAGTCTGTCCCCGGCGACGGCTAGTGGTGACGCTAGCTCTCCGCACGGCGCCACGCTCGTGCAGTTCAGTGCCAACGGAAGCAGCGGAACGACCGGTTCCGGTAGCTCCAGCAACAGCAATTGCAGCCTTTCAAGTAGTTCGAGCAGTAGCAGCTCAagcagtagtagcagcagcagtagtagcagcagcagcagcagcagcagtagtagtagtggcAACGTGAGCGACTCCAACTCCAGCTGCAAGTCACCATCGCCAAGCTCGCCGGCGCCCGGTTCCGGCAACGAGGGTCTCACCCGTCAGCAGCTCGATCTCATCTCGCAGATCATGCAGCAGACGAAGCAAGCGAacgcggccgccgccgccgccgctgccgccgctgcctcctcgtcctcctcctccagctCGAGCAACGCTTCCAACAACACCGCGTCATCCAACACCAACGCTTCGGGTACCGGAGTTGGTGGCCAGAAAGTTCCGCTTCGTCCGCGGACCTGGAACATGCAGGGCACCAGGTTTCCGGCATCGCGACGAAACAGCCAAGCATCGAACGGTGTCTTCGATCCCTTCGCAACGGTCGGTCGGAAGCTGTACAGCCAAAAGCGAGCTGGCAACGGGCCCATTTTCACGCCGGTGCACCGAGCCGCAAGTCCATTCGCAAGTCCCGCCAATGTGGCCAATCGTCGGCATCGGCATCGCTCCCGTGGCGGATGTGAGCATGTCCTTAGCAACTTGCTGTTTATGACTTTCTTCAGCTGCACCTGCTTGAGCCACCTGGCAACGTggCTGCAACTCAGCCAGAACAAGCTGTCCGCAACCGCAAcgtcgtcgacgacgacgacggcgacgctGGTGAGCGCCGTCCCGAGCGTGTCCTCGCTAGCAGCCGCATCGACGGTTGCGTCATCGTCCCTCACCAGCACCCTCgtgtccaccaccaccaccgccaacagcagcaccaacaccaaGGTGCCAAACGCTGGCAGCGCAAGTGCCGATCCTAATGGACCACTCACGGCGCCGTCGGGCTCGGTGTCGTCCACAACTGCGTCCGGTGCGGTCGGTGCGGTTTCGACGGCCAACTCTGCCACGGCAACCACCACActcaccaccgccaccaccactaccaccaccaccagccaaCCCCAGCAATCGGCAAccggcagcaacaacagcaacaacaacaagctcGAGCAGAAACCGGTCGAGTGCAATCTGTGTCACCGCAAGTTCAAAAATATTCCCGCCCTCAACGGGCACATGCGGCTGCACGGGGGCTACTTCAAGAAGGACTCGGAGGCGAAGAAATGTGATAAGAAGGAGAACACCGGGCCACCGCTGCAGACAGCCAGCGTTGGCGTGCGGGCGCTGATCGAGGAGAAGATCATCAACAAGCGAAGCAAGGACCTGAAGAATCTATTGTTGAAGGGTTCGTTCGTGGTGCCGGCGCCGCCCCTGACCGCCCGCCGGCTGATCGAGGCCAGCGAAGCATTCCTCTCGCCGAAGCCGGGCACGGTAGCGATCGTCTCGACGCAGAACGGCACCACGCAGATCATCAACACCGGGACGCTCCACTCGAAGGCAACCATCCTGACGGCGAGTAATGCGGCCAGCACCAGCGCACCACCCGCGATCACGATCAACGggctgacgacgacgacggccgcCGGTACGATCATGGCCACGGGCATCCCGCCCGGGACGGAGCTAAAGGATGCCACGTTGATCGAGCTGCTGAAGCGCGGCACGAAGGTGGCGGTGAAGCGAGCAGCAACGCCGATACtcaaccaacagcagcagtcgGTTGCGTCGTCCATTACGACCACGACCTCGAGCTCTTCGGGAGCCGGGAACCTTATCAGCACCGGTTCGCGATCGGTTGTGCTACCCGGGACGACGAAGCTAACGACGACATCCTCGAGTGGTCTGATGAGCTCGACAGCGGACAGTGGTCCACTTTCGCTGACGATCTCCCAGGCCACGGGAGGTAGTACAGCTGGGGACGTGTTCACACTGGCCTACTCCACCGACACCGGTGGAGGGACGACCTTCTTCAGCGATAACGACGTCTACAGCGTGAGTGAAACGGCAATGCTCCTGCAAGCCGTCGATTCCATCCAGCTATTGCAGGACTCCAACTCCGCCGAACCGCTGGACGAAATCGCCCTCTCGGACTACAGCTCCATCACCGACCAGGGTTTTACGCCGTCGCGCCAGATTCAGGCCGTGCTCGATTCTCCGCTACCCGAGAGTCTCGCCGAGTTCGGGGCTCTCAACTCCAAAGACTTCGTCCTGTACGGGAGCTCGCAGCCGTCGTCCGTTAGTAACGGACCGTCGGGCAACTCCACCGGCGCCGGCACTAACCTGCTCGAGTCACCGTCGGGTGCGCACCTATCTCCGCTTCCCTCACCATTGGCCTACCCAACGCCACCGGCTTCGCATGAGGCGGTGGCCCAGGCATCGCCTTTCCTAGACGACTCGCGCCACTTCACCGATGCGGGTTCGTTCTTCGACGACAAGCGTGGTCAGAACTTCCTCGACGATGGGTTCTTCAAGAGCGAGCCCAAGGGCGATGAACACGGTGCGGGACCGGGAGCGGGTAAGCTTACCGACAGCGAGAAGATACTGGCGCTGAAGAACGAGCTGCTTGACCATGAGCACCACGATCTGTTCCGGTCGAACAAGAACCTGTTGGACGAGCACTGCTCGGAGCTGTTCAAGTCGGAGGATAGCTTTTTCGCCGAATCGAAACCGTCGCCGGTCGACGGGACGTCCAAGATGAACCTGGACTTCCTCGACGACGCGCAGGTGTTCATCGAGGAGACACGGAACGCTGCCTCGCCGCTCTCGAATGCGTTCTTCTCCGCCACCATGCACGCCGCATCCGCCGAGGAGGTGAAGGAGGCGCTCGAGGTGGTACTACCGCACGACGATGACATCGGCGTGTCCGAGGGTGACATCGACCTCTACTACCTGAACGGCCTTTCCTCGCTGCAGTCGCAGATGATGCCCAACTCGGACGATCCGCTGCTGTCGTCCTCGCCGAAAGACTTCGCCCACCGTCAGCATCAGAAGTTCCTGTTCGAGCAGAGCCAGCAGCAAGCGCTGCAACACcatcagcaccagcagcaacaaatccagcagcaacaccttcgacagcagcaacagcagcagcagaatcaTTCATCCACGCACAATCATCCACTGCAGCAGCAAGTGGCCGCCGCCAACAACTGTATGCCACCTAGTGCCAAAAAGTCGAAACCTTGCGTCGGCGACTCCGGGACGATCCTCGCCGGTGACTCGAGCAAGGTCCCACTCACCGTACAAACCGAACCGATGTCCAAGGGCACGGACAGTGTGTTCCTCAGCCCGAGCAGCCTGTCGTCGCACAgctcttcgtcgtcgtcgtcgtcctcgatGGCGACTTCCGCCGCTTCGCCCAAGCTCCAGCACGCCCTCCTAGGAGGCGGTGGAGGAAGTATCATGTGGCCTCGCAAGCGATCCCAGACATCCACCGGAGGCAACGGGCTGAGCCACCCGATGGGGCAACGTAAGCCAACCGTCTACCTGTCCAAGCTGCGCCGTTCGACCACGACGTCCCTCCCGGCCGTTCACTACACGCCTTCGCCTATGCTGAACCCGGAACGAACCGGTTCCACCGGGCTGTACGCAAACGTGGTGCATAATCGCGCGTCCGGCCTGGACACCGATCTCGACAGTACGATGGACAGCACGAGCGACATCTTCTCCGAGCCGCCCCTGCCTATACGGCCCCGGATCAACCTCGGTCCGGACTATCAGGCAACGCTGCCCGACTGCACGCGTCCCAGTGTCTACAGTGCGCTGCAGGGGTACTCCGCAAACCCGACGCAACTGTGGGATCCTGCGGTCGCACACAACGAGCGCCAGGTACAGCGTTTCATCGAACTGGCGCGATCTTCGGCCGCCCCCCTCGGTTGCCACTCGGAGGAGAACGCCCTCCAGGCGCTGCTGGAAGCGAACGGCGAGATTCACGTCGCCATCCTGAGCATGCTGCAAGCGCCACCGGCAAGCATCCATCGCCGCTGGACCGCCGGTGAAATCGAGCAATTCATCCAGGGTCTCGAGAGCTACGGCAAGGACTTCCATCGGATCGCCCGCGAGCTCCTGCCCGCCAAGTCGACGGCCGACTGCGTCCAGATGTACTACTTCTGGAAGAAGCTCTGCATCGACTACAAACATTCGCACGGCGGCGCGCACCGGCTCGTGGACGGGCTGGTGGCGTCCAAGTTCGCCGGTTCATCATCGCCGTCCCCACCACCGACTGCCCCtgcaccacctccaccaccaccaccggtggaAGACCTGTTGATGGACCATCTGGACTATACAAGTACCACGATCGGCTCGGCGAAGGGTCACCACTCGACTCAGTCGACGGCTTCGACGCACGGAAGTGCTCATCAGCCTTCCGGTAACGCACACAATGCGCCCAGCGATGTCCGACCGCACGTATGCGAGGTTCCTGACTGTTCAGCGAGCTTCTCGTCGAAAGCGGCCCTTCACGGTCACATCCGCATTCACTGTATCGGACGTAGCCACAGCGCAATTCAAAATGGTAATTTCTTGAGTGCCGCCGGTAACCCCATTAACCCTAACCTCATACCGACAAAGGATGACTATCCCTGCAAGGTGTGCGGCAAGGTTTTCAATAAGGTAAAAAGCCGAAGCGCCCACATGAAGTCACACCGGCCCCAGGATGCAAGCGATCAACTGCAACACCAGCTGCAactgcaccagcagcagctgcagcaacgCCAGCAAGATAGCGAAAAACAAGGCACCACCGGCGACCAGCAGCCATCCAAATAA
Protein Sequence: MLLNVCLAVQNSIRLPLAGLAPPRVLMCSASMGAEGSVTLQLREAVPAPDATGSLDGALTIGYPDSEMLADMLGTFQGASTGGADSDGGSFDLLQDTGRTAAEQIEHILTKSTASSSSSLGTKAATEKANAITNRLSSSSSTSSSPSSSSSSLSGVLHHGTTMVTVKSAASGSSPSASIAAASPTASTTSLVLTAVGRSETISPAMASGNSSAASSPSAASSPGGLAKKPRPKTVSPTRHGPQQCQVCSKVFGNASALAKHKLTHSDERKYVCGMCSKAFKRQDHLNGHMLTHRNKKPYECKADGCGKSYCDARSLRRHTENHHTALGLAGGASGTASPGPGGGSNAGPPGGLSLSPATASGDASSPHGATLVQFSANGSSGTTGSGSSSNSNCSLSSSSSSSSSSSSSSSSSSSSSSSSSSSSGNVSDSNSSCKSPSPSSPAPGSGNEGLTRQQLDLISQIMQQTKQANAAAAAAAAAAASSSSSSSSSNASNNTASSNTNASGTGVGGQKVPLRPRTWNMQGTRFPASRRNSQASNGVFDPFATVGRKLYSQKRAGNGPIFTPVHRAASPFASPANVANRRHRHRSRGGCEHVLSNLLFMTFFSCTCLSHLATWLQLSQNKLSATATSSTTTTATLVSAVPSVSSLAAASTVASSSLTSTLVSTTTTANSSTNTKVPNAGSASADPNGPLTAPSGSVSSTTASGAVGAVSTANSATATTTLTTATTTTTTTSQPQQSATGSNNSNNNKLEQKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDSEAKKCDKKENTGPPLQTASVGVRALIEEKIINKRSKDLKNLLLKGSFVVPAPPLTARRLIEASEAFLSPKPGTVAIVSTQNGTTQIINTGTLHSKATILTASNAASTSAPPAITINGLTTTTAAGTIMATGIPPGTELKDATLIELLKRGTKVAVKRAATPILNQQQQSVASSITTTTSSSSGAGNLISTGSRSVVLPGTTKLTTTSSSGLMSSTADSGPLSLTISQATGGSTAGDVFTLAYSTDTGGGTTFFSDNDVYSVSETAMLLQAVDSIQLLQDSNSAEPLDEIALSDYSSITDQGFTPSRQIQAVLDSPLPESLAEFGALNSKDFVLYGSSQPSSVSNGPSGNSTGAGTNLLESPSGAHLSPLPSPLAYPTPPASHEAVAQASPFLDDSRHFTDAGSFFDDKRGQNFLDDGFFKSEPKGDEHGAGPGAGKLTDSEKILALKNELLDHEHHDLFRSNKNLLDEHCSELFKSEDSFFAESKPSPVDGTSKMNLDFLDDAQVFIEETRNAASPLSNAFFSATMHAASAEEVKEALEVVLPHDDDIGVSEGDIDLYYLNGLSSLQSQMMPNSDDPLLSSSPKDFAHRQHQKFLFEQSQQQALQHHQHQQQQIQQQHLRQQQQQQQNHSSTHNHPLQQQVAAANNCMPPSAKKSKPCVGDSGTILAGDSSKVPLTVQTEPMSKGTDSVFLSPSSLSSHSSSSSSSSSMATSAASPKLQHALLGGGGGSIMWPRKRSQTSTGGNGLSHPMGQRKPTVYLSKLRRSTTTSLPAVHYTPSPMLNPERTGSTGLYANVVHNRASGLDTDLDSTMDSTSDIFSEPPLPIRPRINLGPDYQATLPDCTRPSVYSALQGYSANPTQLWDPAVAHNERQVQRFIELARSSAAPLGCHSEENALQALLEANGEIHVAILSMLQAPPASIHRRWTAGEIEQFIQGLESYGKDFHRIARELLPAKSTADCVQMYYFWKKLCIDYKHSHGGAHRLVDGLVASKFAGSSSPSPPPTAPAPPPPPPPVEDLLMDHLDYTSTTIGSAKGHHSTQSTASTHGSAHQPSGNAHNAPSDVRPHVCEVPDCSASFSSKAALHGHIRIHCIGRSHSAIQNGNFLSAAGNPINPNLIPTKDDYPCKVCGKVFNKVKSRSAHMKSHRPQDASDQLQHQLQLHQQQLQQRQQDSEKQGTTGDQQPSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109072;
90% Identity: iTF_00096316;
80% Identity: iTF_00109072;