Aste010634.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles stephensi
Gene Symbol
-
Assembly
GCA_013141755.1
Location
CM023248.1:26998515-27002922[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0011 0.065 13.5 6.4 1 23 237 259 237 259 0.98
2 14 1.9e-06 0.00011 22.2 0.2 1 23 290 312 290 312 0.98
3 14 4.4e-07 2.5e-05 24.2 0.8 1 23 318 340 318 340 0.98
4 14 9.9e-07 5.7e-05 23.1 3.5 1 23 346 368 346 368 0.98
5 14 0.00021 0.012 15.8 0.7 1 19 374 392 374 395 0.95
6 14 1.5e-05 0.00088 19.4 0.8 1 23 401 423 401 423 0.98
7 14 1.7e-07 9.8e-06 25.5 1.1 1 23 432 454 432 454 0.99
8 14 9.3e-07 5.4e-05 23.2 0.7 1 23 460 482 460 482 0.99
9 14 0.0073 0.42 11.0 0.3 1 19 489 507 489 508 0.96
10 14 0.00023 0.013 15.7 1.1 1 23 611 633 611 633 0.98
11 14 1e-05 0.0006 19.9 0.6 3 23 691 711 689 711 0.96
12 14 0.00014 0.0083 16.3 0.8 1 23 717 739 717 739 0.93
13 14 1.3e-05 0.00077 19.6 3.1 1 23 747 769 747 769 0.98
14 14 5.3e-09 3e-07 30.3 1.7 1 23 775 797 775 797 0.98

Sequence Information

Coding Sequence
ATGCGAGCTAAagatttgtgttttgtttattacaGCTTTACCCAACGGTACGGCAACAGTAATAACGATATCTGTCGGCTGTGTTTGAAAAATGAGGCCCACATGGAACCGTTGTTCTACGCGAACCTCTTTCCCAACATTTTACTTACGAAAAAGATATACGATTGCACCTCAATTCAGATAATCTACGATCGGAACTTGCCCATGTTTGTGTGCAAACTTTGCGCCAACAAGTTGGACGAATATGTACGATTTCGGGACCGCTGCATAGCGAATGATGAATTTCTCCGCAACGCTCTGGCAGCATTCGATGCGAACGGTGGAAGCTGTTCGAGCACGATTAAGATGGAACCGGAAGACACACCACCGCCCACTTCTTCAGCTCCGCCAACGGCAAAGTTTGCCCAATGCCTTGCGGTAACACCGATGGAGCTGAACTGTGCCCTtgttgcggctgctgctgccgcagcCGGTCACCAGAGCAGCAAACGCGAACCACCGGATGTGGAGGAAACCCATGGACGGTATAGCCATGGGTCGGGTGCTGCCTCtcccgatcgatcgagctgCGGTGGACGGATGACGGCGGTAGATGAGCTACCGCCACGGAAGCATGCACACGATGATCCCTACCGGAGTGGCGAAGAGGAGGACGAGCTAGCTGCCGACGAGGGAACGTACGGAGAACCTAACCCCGGTGCCAATCAGTATGTGTGCGACGTGTGTTCGAAATCGTTCAAAATACGCCACCATTTGCTAGTGCATAGGCACACGCACGTGGACAATCATCCGGCACCGATCAGCGGGTTGCTAAACGGTGGTGGATCCGACTTTAACGGTGGCGTGACCGGGAGCGGCAAACAGTCGTACAATTGTCCCAAATGCGCCAAAGTGTTCGTCAACAAGGGCAATCTGCTTAACCACCTGGAgacgcacacgaacgagaAGAGCTACGCGTGCGATATCTGCACGAAAACGTTCAAATACAATGTGCAGCTACGGTTGCATATGCGCATCCATACCGGCGAACGGCCGCACAAGTGCGAGATCTGCAATCGCGGCTTTTCGCAGCTTTCGAACCTGCGTTCCCACCGGAAAACTCACTCCAAAGTCAAACCGTACAAATGCCATTTATGCCTCAAAAGCTTCACCATGCTGGATAACCTTACCGCACACAGCGCAAAGTGTCTGAAGGACAAGTTCCGCTGCACGCTCTGCTCGAAATCGTTCGCCAAGGAGGGTAACCTCCTGTCGCACCTGCAGTCCCACAGCGATGGCATCGTGGAGAAGATGTTCAAGTGTGAAATGTGCCCGAAAAGCTTCAAAAACAAGGAGGACTGGAAGCGGCACGTGCGCGTGCACACGGGCGAAAAACCGTACACGTGCGATATCTGCTCGAAAGGATTTGCCCAAAAGGCGAATCTACTCTCCCACCGCAAGACACACCTCAAGCCGAACGTGGTTTACAAATGTGAACGATGTGCGCGGACTTTTCGATCGCAGAAAGTCCTCCAAATGCACGTGCCGAAGTGTTCCGGTGCTGGCGCGAACGACGGGACCAGTGTTCCTTCCGCACCGGCCACACCGGTATCGGAATCGGTTCCGGGTTCACCGAGTCCGGGAACAGCAGCCGTAGTTACCATGTCGACTACGGCATCCGCTGCCGTGGCTTCGGCAAACAGTACGCCAACACTCTCGGAAGCACTGTCCGATCTGCTGCGGTACGAGATCGCACTGAGAGCGCCGCTGGAACTGCAGCAAATGCTGCTCGGGCATATTGATCGCAAGAAGCCACAGAATGGCACTGGCGGCAAAGCGACGGGGCGGCGCTACCGGTGTGATGTGTGCTTCAAGGGCTACTCACAGTATCCGTCACTGATCAAACATCGCAAGCTACACTTCAAGGTACCTCCACTGGTAAAGGTTCTGGCGGGTAAAGGTCGACACGATGCAGACTACGAGGACCACGGGGAACCCCTGGAAGCGGCATGCGACGAGCGGCCCGAGGGATTGGAGCGACACCCAGCAACGACACCGGAGCTGCACGATCCGATCGAGCGGCCGTACGGCTGTGATATATGCGGTAAGAACTTTAAATACAATCGTAACCTGAAGGTGCACGCCAAACTGCACATaaaagcgaaccgttttaAGTGTGACAAGTGTACCACCACCTTTGCACAGGTGGAAGATTTGAAGCGGCATCTGCCCACCCACCCGACCGATGCCGGCAGGAGCTTCAGCTGCGAGTACTGCTCGAACCGGTTCCGCTCGAACGAGGACCTGAAGCGGCACCGGCGATCGCACACCGGCGAGCGACCCTTCCGATGCCCGCACTGCCCGAAAGCGTTTACCCAGCAGTCGAACCTGCGGGCCCACACGAGGATCCACGAGCGCTAG
Protein Sequence
MRAKDLCFVYYSFTQRYGNSNNDICRLCLKNEAHMEPLFYANLFPNILLTKKIYDCTSIQIIYDRNLPMFVCKLCANKLDEYVRFRDRCIANDEFLRNALAAFDANGGSCSSTIKMEPEDTPPPTSSAPPTAKFAQCLAVTPMELNCALVAAAAAAAGHQSSKREPPDVEETHGRYSHGSGAASPDRSSCGGRMTAVDELPPRKHAHDDPYRSGEEEDELAADEGTYGEPNPGANQYVCDVCSKSFKIRHHLLVHRHTHVDNHPAPISGLLNGGGSDFNGGVTGSGKQSYNCPKCAKVFVNKGNLLNHLETHTNEKSYACDICTKTFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTMLDNLTAHSAKCLKDKFRCTLCSKSFAKEGNLLSHLQSHSDGIVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHRKTHLKPNVVYKCERCARTFRSQKVLQMHVPKCSGAGANDGTSVPSAPATPVSESVPGSPSPGTAAVVTMSTTASAAVASANSTPTLSEALSDLLRYEIALRAPLELQQMLLGHIDRKKPQNGTGGKATGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLAGKGRHDADYEDHGEPLEAACDERPEGLERHPATTPELHDPIERPYGCDICGKNFKYNRNLKVHAKLHIKANRFKCDKCTTTFAQVEDLKRHLPTHPTDAGRSFSCEYCSNRFRSNEDLKRHRRSHTGERPFRCPHCPKAFTQQSNLRAHTRIHER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00100445;
90% Identity
iTF_00104071;
80% Identity
-