Basic Information

Insect: Anopheles sinensis
Gene Symbol: lrrfip2
Assembly: GCA_000441895.2
Location: KE525369.1:352405-359910[-]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1 1.5e+04 -5.8 1.8 67 87 139 159 131 166 0.49

2 3 1.4e-110 2.2e-106 355.3 34.8 1 299 214 512 214 513 0.94

3 3 0.051 8e+02 -1.1 2.8 210 246 532 567 516 586 0.60

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1	1.5e+04	-5.8	1.8	67	87	139	159	131	166	0.49
2	3	1.4e-110	2.2e-106	355.3	34.8	1	299	214	512	214	513	0.94
3	3	0.051	8e+02	-1.1	2.8	210	246	532	567	516	586	0.60

Sequence Information

Coding Sequence: ATGAGTGTCACAAGCCGGCAGCAGGCGAATGCTGATGATGACGCTAGTGACAGCAGTAGCGTGGGTGACATTTACGAGCTGGCGCACAGTGAGCTGTACGGGCCGTCGGGCCCTGCGATCGGAGAGGGTCGTCCGGAGCAGGCCGGTAATGGGGTCGACGCCGTGGAGTCGCCACCGTCGTTGGGGTTCGACAAAGCTACCGCCAGCGACGGCGGGTCGGTTGACATTAACCGCAATCGGATCGCACCGGAGGCTAACGGGCCGGAGGATCGCTCGCTGACCAGCGTGTACAGCGACGCTGGCGTCGAGGAGGTCCTCGGGCGTCGAGCTAGCTTTGAATGTGACCTATCTTCACCCGACCAGCACGACGGTGGACCACAGCCCCACTCGGAGGAGCTCAACGACCGGAGCGATGACAGCCGGAACAGCAGTAGTCTGCGCAGCGACAGCTACCATGACTCCTCGTCCATGCACGAGCCGCACCAGCAGCACCAGCAGCAGCACGGAGGCCACGGGCACCATCCGTCGTACGAGCCGCACCGCCAGTACCATCGCCTCTCGGTTAGTCACACCGGCGACGAGTTCAGCTCCGAGGAGGACGATGCGTTCGTAGAGTTGCTCGAGCGGGCGAATGACATCGCGGAAGCCCGGTTAGCAGCCAGGCGGCAGGCAAGGGCGGAAGCCCGCGAGATACGTATGCGCGAGCTGGAGCGCCAGCAGAAGGAGCTGGAACAGAATGCGGACCGGGTGTTCGACCTGCAGCAGCAGTCGATCGGACTGTCCGGCGAGCCGGTCAGTCTGGACCGTACCACAACGCCGCGCTCGAGCCGAATGATGGCGCAGGGATCGGCCAGTGCGGCCCGCGGCAGTGCCCTCTCGTCCCGCCGCAACTCGGAGGATTCGCTCGAGGAGGAGGCGCGCAGCTTACGCGATCTGCGGCACGAGCTGAAGGATGTGGAGGAGCGGTTCCGTAAGGCGATGATTGCGAACGCGCAGCTAGACAACGAGCGGTCGTCGCTCAACTACCAGATACAGCTGCTGAAGGACAAGCTGGAGGAGATGGAGGAGTCGCACACGCAACTGCAGCGCGAGTATCGGGAGAAGTGCCGCGACCGGGAGGCGCTCAAGCGCAACAACGACAAGCTGAGCGAGGAGCTGAAGCTCGTCCAGGGCCAGCTGCAGGAGCGGGACGCGCTTATAGAGCAGTACGGGCTGGTCATAGTGACGGTGGAGAACGAGGACGGTACCGATGCGCATCGCGCCCTAGTCACAGCGGACAACGCACAGTTGCTCAAAACCGTACCGGGTTCGTTAGACGTAAGACTGAAGAAGTTTGCCGAGGAAAAGCAGGAACTACAGAGCGAGCTGCAGACACTGCAGCAGCAACTGAACGACTTCAAAAGCAAGGGCCGCCGGAATACCTGCTCGAACGGGTTCGGTCTGGCCGACGATGACTACGAGGACGCGCAGCGCGAAGCCAACAAGCTGATAACTGAGTATAAATACAAACTGCAGAAGGCGGAGCAGGAGATTGCGAACCTGCAGGCCAGCCTTGCCCGATCGGAGACTCAGGTGATTCGATACAAGAGCACCGCCGAGGCAGCTGAGAAGGCCGAGAGCGATCTGAAGATCGAGCGGCGAAAGTTGCAGCGCGAGAATCGCGAAGCGATGGACCGCCTAGAGGAGCTGGAAACATCGAACAACCATCTGCTGAAGCGGCTGGACAAGCTAAAGAACGTCAAAAGCAATATTCTGAAGGACATTTGA
Protein Sequence: MSVTSRQQANADDDASDSSSVGDIYELAHSELYGPSGPAIGEGRPEQAGNGVDAVESPPSLGFDKATASDGGSVDINRNRIAPEANGPEDRSLTSVYSDAGVEEVLGRRASFECDLSSPDQHDGGPQPHSEELNDRSDDSRNSSSLRSDSYHDSSSMHEPHQQHQQQHGGHGHHPSYEPHRQYHRLSVSHTGDEFSSEEDDAFVELLERANDIAEARLAARRQARAEAREIRMRELERQQKELEQNADRVFDLQQQSIGLSGEPVSLDRTTTPRSSRMMAQGSASAARGSALSSRRNSEDSLEEEARSLRDLRHELKDVEERFRKAMIANAQLDNERSSLNYQIQLLKDKLEEMEESHTQLQREYREKCRDREALKRNNDKLSEELKLVQGQLQERDALIEQYGLVIVTVENEDGTDAHRALVTADNAQLLKTVPGSLDVRLKKFAEEKQELQSELQTLQQQLNDFKSKGRRNTCSNGFGLADDDYEDAQREANKLITEYKYKLQKAEQEIANLQASLARSETQVIRYKSTAEAAEKAESDLKIERRKLQRENREAMDRLEELETSNNHLLKRLDKLKNVKSNILKDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00096382; iTF_00109141;
90% Identity: iTF_00096382; iTF_00109141;
80% Identity: -