Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: grau
Assembly: GCA_000349065.1
Location: KB665954.1:1111212-1114486[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.5 2.2e+02 2.1 0.3 1 9 32 40 32 46 0.88

2 13 2.1 1e+02 3.1 0.1 3 23 203 226 201 226 0.79

3 13 1.8e-05 0.00087 19.1 0.4 2 23 234 255 233 255 0.96

4 13 3.4 1.7e+02 2.5 0.6 12 23 311 323 309 323 0.83

5 13 0.0027 0.13 12.2 0.6 2 23 331 352 330 352 0.98

6 13 0.074 3.6 7.7 0.1 9 23 440 455 438 455 0.90

7 13 0.0058 0.28 11.2 0.9 2 23 463 484 462 484 0.96

8 13 1.4e-05 0.00066 19.5 0.3 1 23 515 538 515 538 0.96

9 13 0.0038 0.19 11.8 0.5 3 23 545 565 543 565 0.95

10 13 3.1e-06 0.00015 21.5 0.1 1 20 571 590 571 592 0.95

11 13 0.00076 0.037 13.9 0.6 3 23 626 647 625 647 0.97

12 13 2.7e-05 0.0013 18.5 2.2 2 20 654 672 654 674 0.94

13 13 5.7e-05 0.0028 17.5 2.7 3 23 683 703 681 703 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.5	2.2e+02	2.1	0.3	1	9	32	40	32	46	0.88
2	13	2.1	1e+02	3.1	0.1	3	23	203	226	201	226	0.79
3	13	1.8e-05	0.00087	19.1	0.4	2	23	234	255	233	255	0.96
4	13	3.4	1.7e+02	2.5	0.6	12	23	311	323	309	323	0.83
5	13	0.0027	0.13	12.2	0.6	2	23	331	352	330	352	0.98
6	13	0.074	3.6	7.7	0.1	9	23	440	455	438	455	0.90
7	13	0.0058	0.28	11.2	0.9	2	23	463	484	462	484	0.96
8	13	1.4e-05	0.00066	19.5	0.3	1	23	515	538	515	538	0.96
9	13	0.0038	0.19	11.8	0.5	3	23	545	565	543	565	0.95
10	13	3.1e-06	0.00015	21.5	0.1	1	20	571	590	571	592	0.95
11	13	0.00076	0.037	13.9	0.6	3	23	626	647	625	647	0.97
12	13	2.7e-05	0.0013	18.5	2.2	2	20	654	672	654	674	0.94
13	13	5.7e-05	0.0028	17.5	2.7	3	23	683	703	681	703	0.97

Sequence Information

Coding Sequence: ATGTTCATGCCGCGGGAGGACGACCCGAAGGAGATGCCGTATCTGGTGTGGAAGCACGTCGGGCTACAGTTTCCGCAGGAGGCAGGCAAACACTACGTCTGCCGAGACTGCGGGTACGCAGTGTACGAGTTTAACCGATTCTACTTGATGGTGCAGAACGTCCACCAGGAACGGCAGGCTGCTGCGGCGGCAGCAGTACTGCAACCGAAGCAAGAGCCGCCTATGCAGGAGCAGGTACAATATAATGCTGAGCAGGCGGCGGCGGCGGCAGCGGTGGAAGGCGTCAATCAGAACGGTCATCATGGAGGCGAGCAAAAGTTTGACCCGTCGCCGCTGGTGGACGGGCCCGTGCCGTTGCTGTCCGATGTTCCGGATTATGGGATGAAGCACGAAGTGAACGGAATGCTACCATCCGGCGGATCCGGGGTAACGGCTGTCGGGGGCAACGGTACAGCGGCAGAGTGTCCGTCGGTGTACACGTCGCAGCACAACGATACGGAACCGGAAAGCAGCCGAATCCGGCCGGTCACGGGCAACACACCGAGCAGCCGGAAGCGCCGCAACCAAGAGATGGACGATGAGATTATCGACTTTTACAAGCTGGTCTGTGACGTGTGCGAGGAACGCATCGAGTACGGCACGATGAAGGAGCTGAACCAGCACATGAAGCTGATGCACGGGGAGGAGACGGGCCGGGTCAGCTGTCCGCAGTGTGGCAAGATGTTCCGCACGCGGGGGAAGCTGCTGGAGCACAAGAGCGTGCACCAGCGGCAGGACGCCACATCCGAGGACGACGCGGAGAAGCTACAGTCCGAGCAGATGGACAAGGAGATACTGGAGTTTTACAAGCGCATCAGCTGCGATGTGTGCGACACGGCGGCCAGTGCTGCTGCCGGGGCCGGTCCACAGGCCAGCGCGATGCTGTACGCGACGGTGAAGGAGCTAAACCACCACATGCGACTGGTGCACGGGCAGCAGGCCGGTACGGTAAAGTGTCCACTGTGTGAGAAGAAGATCCGTACGCGCCCGAAGCTGCTCGAGCACAAGCGCATGCACCAGCCAAACGCGCTGCTGGAGGAAGATTCCGGCAAGTCGGGCAACCCGGGCGGCGAGCCGGGGCCCGAGCTGACCGAGGAGCAGAAGCAGACGCTAGATAGAGAAATATTCGATTTCTACAAACCCATCATATGTGAGATTTGCGATCCGGAAAAGGTCGCTGTGGCTGTCGCGGTGGCCGGCGTCGGCGGTGACCCGGGCGGTGTTGCCGCGGGAGCGGGCCAGCCGGAAGCGGCAGGAGCAGCAACGACCCAGGAGGAGGAGTACCGGTCGCTGAAGCAGCTGAACCAGCACATGCGGACGGTGCACGGGCTCGAGTCGGGCACGGTCAAGTGTCAGCTGTGCGCGAAAAAGTTTCGCTCGCGCGTCAAGCTGGTCGAGCATAAGGATATGCACGAGAATCCGGAGCGGTTCCGGTGCGGCGTGTGCCAGGAGGTGCACCAGAACCTGGAGGAGCACATGCAGAACAAGCACCAGGAGTGGGAGTTTGCCTGCGAGGAGTGTGGCAAGCGGTTTCCTTTCAAGAACAGACTCACTGCCCACATGGCCAAGGTGCACATGAAGAAGGACATTATCTGTGAGGAATGTAACAAACCATTTACAAAGTTCAGCATCGAGAAACACAAGAAAACGGTCCACGGCCACGGTGGGACGTTCATTTGTGAAAACTGCCCGAAAACGTTCAAGACGCGCGTCTCGCTCGAACGACACATGGAGGGGCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTGCTCCCTGTGCAACTCCGTCCTGAAGGACGAGTACAACCTGAAGGCCCACATGAAGCGCATCCACGCGGAGCAGACGCCGGCGACGTGCAACACGTGCGGCAAGACGTTCAAATCGAAGCACAGTCTCAACACGCACACCGCGAACGTGTGCACGACCCGGCTCTTTGGCTGCACGACCTGCGGCAAGCAGTTTAAGAAGCGGACAAAGTTGAAACAACACATGACGATTCACCCACGCGGCGCCGACTAA
Protein Sequence: MFMPREDDPKEMPYLVWKHVGLQFPQEAGKHYVCRDCGYAVYEFNRFYLMVQNVHQERQAAAAAAVLQPKQEPPMQEQVQYNAEQAAAAAAVEGVNQNGHHGGEQKFDPSPLVDGPVPLLSDVPDYGMKHEVNGMLPSGGSGVTAVGGNGTAAECPSVYTSQHNDTEPESSRIRPVTGNTPSSRKRRNQEMDDEIIDFYKLVCDVCEERIEYGTMKELNQHMKLMHGEETGRVSCPQCGKMFRTRGKLLEHKSVHQRQDATSEDDAEKLQSEQMDKEILEFYKRISCDVCDTAASAAAGAGPQASAMLYATVKELNHHMRLVHGQQAGTVKCPLCEKKIRTRPKLLEHKRMHQPNALLEEDSGKSGNPGGEPGPELTEEQKQTLDREIFDFYKPIICEICDPEKVAVAVAVAGVGGDPGGVAAGAGQPEAAGAATTQEEEYRSLKQLNQHMRTVHGLESGTVKCQLCAKKFRSRVKLVEHKDMHENPERFRCGVCQEVHQNLEEHMQNKHQEWEFACEECGKRFPFKNRLTAHMAKVHMKKDIICEECNKPFTKFSIEKHKKTVHGHGGTFICENCPKTFKTRVSLERHMEGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSLCNSVLKDEYNLKAHMKRIHAEQTPATCNTCGKTFKSKHSLNTHTANVCTTRLFGCTTCGKQFKKRTKLKQHMTIHPRGAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101146;
90% Identity: iTF_00104589;
80% Identity: -