Basic Information

Insect: Anopheles punctulatus
Gene Symbol: thap1
Assembly: GCA_000956255.1
Location: JXXA01005760.1:5073-7542[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.2 98 3.5 0.0 2 12 156 166 155 169 0.89

2 9 0.05 4.1 7.8 0.7 2 20 479 497 478 499 0.89

3 9 0.16 14 6.2 3.1 3 21 511 529 510 530 0.92

4 9 6.5e-08 5.4e-06 26.3 0.8 1 23 575 597 575 597 0.98

5 9 0.0029 0.24 11.7 0.3 1 21 605 625 605 626 0.95

6 9 3.2e-05 0.0026 17.8 0.7 1 19 685 703 685 707 0.94

7 9 1.2e-06 0.0001 22.3 0.3 3 23 715 735 713 735 0.97

8 9 3.8e-06 0.00031 20.8 0.3 1 23 741 764 741 764 0.95

9 9 0.18 15 6.0 0.1 1 17 770 786 770 787 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.2	98	3.5	0.0	2	12	156	166	155	169	0.89
2	9	0.05	4.1	7.8	0.7	2	20	479	497	478	499	0.89
3	9	0.16	14	6.2	3.1	3	21	511	529	510	530	0.92
4	9	6.5e-08	5.4e-06	26.3	0.8	1	23	575	597	575	597	0.98
5	9	0.0029	0.24	11.7	0.3	1	21	605	625	605	626	0.95
6	9	3.2e-05	0.0026	17.8	0.7	1	19	685	703	685	707	0.94
7	9	1.2e-06	0.0001	22.3	0.3	3	23	715	735	713	735	0.97
8	9	3.8e-06	0.00031	20.8	0.3	1	23	741	764	741	764	0.95
9	9	0.18	15	6.0	0.1	1	17	770	786	770	787	0.82

Sequence Information

Coding Sequence: ATGCCGGCATCATGCATAATATCGGATTGCAATTTAAAGTATACGCACAGCGAAGATGTCTCGTTCCATAAATTTCCACTTAAAAATCCCGAGCTACTAGAACGATGGATGCAGTTTGCTGGTCGTGGCGAGAATTGGCGTCCTACCAAATGGAGTGCAATATGTAGCAGGCATTTTGTGGCAAGCGACTTCAAAGACTGTTCCTTTCGAAAGATTCTCCTGCCATCGGCCGTACCTTCAGTGCGGACGGTTACTTCGAAATTTCATCCAGTCGACCTTTCGGCGCTGCCTGTCATATCGTACGAAACAGTTTGGTCAGAGGATGGACGTCCCCTGCCACGCAGTGAGGCCTACCTATCCCAAGAACCGGTAGCATTTGACCAGAATGCAACCCTCGTCACGGTTTCGGACGGAGGGGAAGACTTTGGAATTGATGGGGATGATGACATGCTGTTGATACAGATAACCTGTCGCATATGTGGCGTCATTTTTAGTCGTGTGGCAGATAGTCTTCTAGCTGATCTCGTACAAACGGAGGATTTGGTTCGCAAATACCTCCCCTTCGTGAATCTTGAACTACCGAATTTACCTCGTAAAATATGCCTCAACTGCTCGAAGGTAGTGAACGGGTTCTCAAAGTTTAGTGAAAGTGTTCTCCGTGCCCAATCGGATCTGGAGCATCGATTTGCGCCACAGCCAGCCAGGACGAATGCAGCACCAACTATAGCACCACCAGTGGGTGCGAGAACCAAACAGGAAAACGCCGCCGGGAAACCCATGAATATCAAACAGGAACCGATCGCAAGTATAAATATtaaggaggaaaaaatcgaGTACGCACGACAGAAAGACTTCCTACCGGTTGAGGAACCAATCGAAGGGCCGGTGATAGTTAAGAACCAGACGTTCGGCGGTGAACCAAATAGAATCTATTTAttcaacaacatcaaccaGGATCTCCCTAATGGTGCTTCAACCAGTGCCACATTGGCTGCCCAGCAAAGCCGGGAACCTTCGAAAAACTGTGAAATACTTGAAATAGTCAATCTTTATCCTCCGATCGTGGACATAACTAGCGCGACGGTGACGGAGGTCCAACCGTACGAGATCACACTGCCATCGGTTGCCACGGCAACTTCAACCGAATCGTTCCCATCGTTGTCTACTACGACCGCATATTCGGCACAGTTGAAAGTGGAAAACACCGCTGAACTAGACACGGAACAGGATGATTATTATCTTCccgaaaaaaatagtttcatcaaCACGCTGGAGGAGCACAGCTACACCAAACTTCCGATTCAGGCGGATGATAATAAGGATGAAATTTTACACGACATGGTCATCGGTAGTCAGAGCAAGTGGTTCGGCAGTGAGAACGTGATTACGGCAGTGAAGAACAAACCGTCACCGCCGAGAAGCATACGACGCTGGTCATGCACAAACTGTGACCGACGGTTTGTCCGTCATCGACGAATGATGGAACACCGTACGTGGGAGTGCCCCGGACGAAGGAAACCATCCGCCAGCTGTCAATTTTGCCGTCGAAAATTTTGCTCCTGGTCGATGGCAAGAGCTCACGTTTGCGTCTGCCCGAAACGAGCGTTGAAACATAGCAGgctaaaatggaaaatgattttggAAAAAGATAGAATGAGGCGAAAGGATTTGTGGAAACTCGATGGTCTACGAGCAGACCAAGAGGAAGTGGTCGTCACGAAATATCCCTGCTCGATGTGTGATCGGTCGTACTCGAATGCATCGAATTTACGCCGGCACCTCACGACACACCGGCCGCAAGAGCAATGGAACCACAAGTGTGGCGTTTGCTTCACAGTGTTCGACAAGTTGATCGACTTGAAGCGCCATCTACAGATCGCACCCTGTGGCAACGCTGGCAATACAATCGCGGTGCAGGCATCGGATACGCATGGCGTAGAGATTGAGCTACCAGCGGAGGTCCCACTGCCAAATGTTCCCGAACCGAGACCGCTCGAAGATATGGCCGTAGTACCGTCGATAGCACCAAGTACCACCGTCGATCGGTTGCTCTACGTGTGCTCGACCTGTaataaaatcttcaaatcGTACAGCAATCTCAAAATGCACGAACCAATACACACCGGAGTGAAAACGTCCATCTGCGAAACGTGCGGCAAACGGTTCACTGGCCCGTCGAACCTGTGGCAGCACCGGCTCACACACTCCGAGGTACGCCAGTTCAACTGCAACCAGTGCCCGAAGGTGTTCAAACGGAAGGGCGGTCTCAGTCAGCACGTGCGCGCTATCCACATGAACATTAAACCGTACCAATGTCCCACCTGCGGGCATGAGTACGCCCTCAAAGCCGACATGACGCGCTGTCGGCATTCCCGGCTGCACGATTCGACGACTCCAGCATGCTAG
Protein Sequence: MPASCIISDCNLKYTHSEDVSFHKFPLKNPELLERWMQFAGRGENWRPTKWSAICSRHFVASDFKDCSFRKILLPSAVPSVRTVTSKFHPVDLSALPVISYETVWSEDGRPLPRSEAYLSQEPVAFDQNATLVTVSDGGEDFGIDGDDDMLLIQITCRICGVIFSRVADSLLADLVQTEDLVRKYLPFVNLELPNLPRKICLNCSKVVNGFSKFSESVLRAQSDLEHRFAPQPARTNAAPTIAPPVGARTKQENAAGKPMNIKQEPIASINIKEEKIEYARQKDFLPVEEPIEGPVIVKNQTFGGEPNRIYLFNNINQDLPNGASTSATLAAQQSREPSKNCEILEIVNLYPPIVDITSATVTEVQPYEITLPSVATATSTESFPSLSTTTAYSAQLKVENTAELDTEQDDYYLPEKNSFINTLEEHSYTKLPIQADDNKDEILHDMVIGSQSKWFGSENVITAVKNKPSPPRSIRRWSCTNCDRRFVRHRRMMEHRTWECPGRRKPSASCQFCRRKFCSWSMARAHVCVCPKRALKHSRLKWKMILEKDRMRRKDLWKLDGLRADQEEVVVTKYPCSMCDRSYSNASNLRRHLTTHRPQEQWNHKCGVCFTVFDKLIDLKRHLQIAPCGNAGNTIAVQASDTHGVEIELPAEVPLPNVPEPRPLEDMAVVPSIAPSTTVDRLLYVCSTCNKIFKSYSNLKMHEPIHTGVKTSICETCGKRFTGPSNLWQHRLTHSEVRQFNCNQCPKVFKRKGGLSQHVRAIHMNIKPYQCPTCGHEYALKADMTRCRHSRLHDSTTPAC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00099206; iTF_00103226; iTF_00100510; iTF_00100349;
90% Identity: iTF_00103226;
80% Identity: -