Basic Information

Insect: Anopheles farauti
Gene Symbol: thap1
Assembly: GCA_000473445.2
Location: KI915043.1:14359106-14361585[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.52 31 4.9 0.0 2 12 156 166 155 169 0.89

2 9 0.079 4.7 7.4 0.4 3 20 482 499 480 501 0.89

3 9 0.19 11 6.2 0.8 3 21 513 531 512 532 0.92

4 9 5.8e-08 3.4e-06 26.7 0.7 1 23 577 599 577 599 0.98

5 9 0.0035 0.21 11.7 0.3 1 21 607 627 607 628 0.95

6 9 3.9e-05 0.0023 17.8 0.7 1 19 689 707 689 711 0.94

7 9 1.5e-06 8.7e-05 22.3 0.3 3 23 719 739 717 739 0.97

8 9 4.6e-06 0.00027 20.8 0.3 1 23 745 768 745 768 0.95

9 9 0.22 13 6.0 0.1 1 17 774 790 774 791 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.52	31	4.9	0.0	2	12	156	166	155	169	0.89
2	9	0.079	4.7	7.4	0.4	3	20	482	499	480	501	0.89
3	9	0.19	11	6.2	0.8	3	21	513	531	512	532	0.92
4	9	5.8e-08	3.4e-06	26.7	0.7	1	23	577	599	577	599	0.98
5	9	0.0035	0.21	11.7	0.3	1	21	607	627	607	628	0.95
6	9	3.9e-05	0.0023	17.8	0.7	1	19	689	707	689	711	0.94
7	9	1.5e-06	8.7e-05	22.3	0.3	3	23	719	739	717	739	0.97
8	9	4.6e-06	0.00027	20.8	0.3	1	23	745	768	745	768	0.95
9	9	0.22	13	6.0	0.1	1	17	774	790	774	791	0.82

Sequence Information

Coding Sequence: ATGCCGGCATCATGCATAATATCGGATTGCAATTTAAAGTACACGCACAGCGAAGATGTCTCGTTCCATAAGTTTCCACTTAAAAATCCCGAGCTACTAGAACGATGGATGCAGTTTGCTGGTCGTGATGAGAATTGGCGTCCTACCAAATGGAGTGCAATATGTAGCAGGCATTTTGTGGCAAGCGACTTCAAAGACTGTTCCTTTCGAAAGATTCTCCTGCCATCGGCCGTACCTTCCGTGCGGACCGTTACTTCGAAATTTCATCCAGTAGACCTTTCGGCGCTGTCGGTCATATCGTACGAGACAGTTTGGTCAGAGGATGGACGTCCCCTGCCACGCAGTGAGGCCTACCTATCGCAAGAACAGGTAGCGTTTGACCAGAATGCAACGCTCGTCACGGTTTCGGACGGAGGGGAAGACTTTGGAATTGAGGGGGATGATGATATGCAGTTGATACAGATAACCTGTCGCATATGTGGTGTCGTCTTCAGTCGTGTGGCAGATAGTCTTCTAGCTGACCTCGTGCAAACGGAAGATTTGGTTCGCAAATACCTGCCCTTCGTGAATCTGGAGCTACCGAACTTACCTCGTAAGATATGCCTCAACTGCTCGAAAGTAGTGAACGGGTTCTCAAAGTTTAGTGAAAGTGTGCTCCGTGCCCAGTCGGATCTGGAGCATCGATTCGCGCCACAGCCTGCCAGGACGAATGCAACACCAACTATCGCACCACCAGTGGGTGCGAGAACCAAACAGGAGAACGCCGCCGGGAAACCTATGAGCATCAAACAGGAACCGATCGCAAATATTAATATTAAGGAGGAAAAAACCGAATACGCAAGACAGAAAGACTTCCTGCCGGTTGAGGAACCAATCGAAGGACCGGTGATAATTAAAAACCAGACGTTCGGCGCTGAACCAAATAGAATCTATTTATTCAACAACATCAACCAGGATCTCACTAATGGTGCTTCAACCAGTGCCACACTGGCTGCCCAGCAAAGCCGGGAACCTTCGAAAAACTGTGAAATACTTGAGATAGTCAATCTTTACCCTCCAATCGTGGATATAACCAGCGCGACGGTGACAGAGGTACAACCGTACGAGATCACAATGCCATCGGTTGCCACGGCAACCTCAACCGAATCATCCGCATCGTTGTCTACTACGGCTGCCTATTCCGCACAGTTGAAAGTGGAAAACACAGCAGAACTAGACGCGGAACAGGATGATTATTATCTTCCAGAAAAAATCAGCTTCATCAACACGCTGGAGGAACACAGCTACACCAAACTTCCGATTCAGGCGGACGATAATAAGGATGAAATTTTACACGACATGGTCATGGTCGGTAGTCAGAGCCAGTGGTTTGGCAGTGCGAACGTGATTACGGCAGTGAAGAACAAACCGTCGTCACCACCGAGAAGCATACGACGCTGGGCATGCACAAACTGTGACCGACGGTTTGTCCGTCATCGACGAATGATGGAACACCGTACGTGGGAGTGTCCCGGGCGAAGGAAACCATCCGCCAGCTGTCAGTTTTGCCGTCGAAAATTTGGCTCCTGGTCGATGGCAAGAGCTCACGTTTGCGTCTGCCCGAAACGGGCGTTGAAACATAGTAGGCTAAAATGGAGAATGATATCGGAAAAAGATAAAATGAAGCAAAAGGAGTTGTGGAAACTCGCTGGCCAACGACCATACCAAGAGGAAGTGGTCGTCACGAAATATCCCTGCTCGATGTGTGATCGATCGTACTCGAATGCATCGAATCTACGCCGGCACCTCTCGACACACCGGCCGCAAGAGCAATGGAACCACAAGTGTGGCGTTTGCTTCACAGTGTTCGACAAGTTGATCGATTTGAAGCGCCACCTGCAAATCGCTCCCTGTGGCAACGCTGGCAATACAATCGCGGTACAAGCTTCCGATACGCATGGCGTAGAGGTTGAGCTACCAGCGGAGCTGCCAGTCCCACTGCCAAATGTTCCCGAATCGCGACCACTCGACGATATGGCCGCAGTACCATCGATCACACCAAGTACCACCGTCGATCGGTTGCTCTACGTCTGCTCGACCTGTAATAAAATATTTAAATCGTACAGCAATCTCAAAATGCACGAACCGATACACACCGGTGTGAAAACGTCCATCTGCGAAACGTGCGGCAAACGGTTCACTGGCCCGTCGAACCTGTGGCAGCATCGGCTCACACACTCCGAGGTACGCCAGTTTAACTGCAACCAGTGCCCGAAGGTGTTCAAACGAAAGGGCGGTCTCAGTCAGCACGTGCGCGCTATCCACATGAACATTAAACCGTACCAATGTCCCACCTGCGGCCATGAGTACGCCCTCAAAGCCGATATGACGCGCTGTCGGCATTCCCGGCTGCACGATTCGACGACTCTCGCATGCTAG
Protein Sequence: MPASCIISDCNLKYTHSEDVSFHKFPLKNPELLERWMQFAGRDENWRPTKWSAICSRHFVASDFKDCSFRKILLPSAVPSVRTVTSKFHPVDLSALSVISYETVWSEDGRPLPRSEAYLSQEQVAFDQNATLVTVSDGGEDFGIEGDDDMQLIQITCRICGVVFSRVADSLLADLVQTEDLVRKYLPFVNLELPNLPRKICLNCSKVVNGFSKFSESVLRAQSDLEHRFAPQPARTNATPTIAPPVGARTKQENAAGKPMSIKQEPIANINIKEEKTEYARQKDFLPVEEPIEGPVIIKNQTFGAEPNRIYLFNNINQDLTNGASTSATLAAQQSREPSKNCEILEIVNLYPPIVDITSATVTEVQPYEITMPSVATATSTESSASLSTTAAYSAQLKVENTAELDAEQDDYYLPEKISFINTLEEHSYTKLPIQADDNKDEILHDMVMVGSQSQWFGSANVITAVKNKPSSPPRSIRRWACTNCDRRFVRHRRMMEHRTWECPGRRKPSASCQFCRRKFGSWSMARAHVCVCPKRALKHSRLKWRMISEKDKMKQKELWKLAGQRPYQEEVVVTKYPCSMCDRSYSNASNLRRHLSTHRPQEQWNHKCGVCFTVFDKLIDLKRHLQIAPCGNAGNTIAVQASDTHGVEVELPAELPVPLPNVPESRPLDDMAAVPSITPSTTVDRLLYVCSTCNKIFKSYSNLKMHEPIHTGVKTSICETCGKRFTGPSNLWQHRLTHSEVRQFNCNQCPKVFKRKGGLSQHVRAIHMNIKPYQCPTCGHEYALKADMTRCRHSRLHDSTTLAC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00106552;
90% Identity: iTF_00103226;
80% Identity: iTF_00100349;