Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02022216.1:969-3165[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00015 0.0083 16.3 2.2 2 23 243 264 242 264 0.97

2 10 5.3e-09 2.8e-07 30.4 1.2 1 23 270 292 270 292 0.99

3 10 7.8e-05 0.0042 17.3 0.1 1 23 298 321 298 321 0.95

4 10 0.00063 0.034 14.4 0.7 1 23 330 352 330 352 0.96

5 10 0.0029 0.16 12.3 0.0 2 23 359 380 358 380 0.96

6 10 6.3e-06 0.00034 20.7 1.5 1 21 390 410 390 411 0.96

7 10 1.1e-06 5.9e-05 23.1 0.9 2 23 419 440 418 440 0.93

8 10 4.6e-06 0.00025 21.2 6.6 1 23 446 468 446 468 0.99

9 10 1.2e-05 0.00062 19.9 2.5 1 23 474 496 474 496 0.99

10 10 0.00045 0.024 14.9 3.3 1 23 501 524 501 524 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00015	0.0083	16.3	2.2	2	23	243	264	242	264	0.97
2	10	5.3e-09	2.8e-07	30.4	1.2	1	23	270	292	270	292	0.99
3	10	7.8e-05	0.0042	17.3	0.1	1	23	298	321	298	321	0.95
4	10	0.00063	0.034	14.4	0.7	1	23	330	352	330	352	0.96
5	10	0.0029	0.16	12.3	0.0	2	23	359	380	358	380	0.96
6	10	6.3e-06	0.00034	20.7	1.5	1	21	390	410	390	411	0.96
7	10	1.1e-06	5.9e-05	23.1	0.9	2	23	419	440	418	440	0.93
8	10	4.6e-06	0.00025	21.2	6.6	1	23	446	468	446	468	0.99
9	10	1.2e-05	0.00062	19.9	2.5	1	23	474	496	474	496	0.99
10	10	0.00045	0.024	14.9	3.3	1	23	501	524	501	524	0.98

Sequence Information

Coding Sequence: ATGATCAACAAAATCAGCGCATTCGAGCGCCAAGACAACCCGAGGCTTCCGGACAGATTGTGTTTCGTGTGTGCGGAACAGCTCCGGATCGCGTACGGCTTTCAGCAGATGTGTGACGATTCGTACCGGATTCTTCTCATCCAATTGGAGAAACAACCGGAGCCAGTAGTACCAAAGGAAGAACCCGTCATCATCGACGTGGACGCGCTAGGGCTGTCTGAAACTGAGCAGGACGAAAGCGAACAGAAAGAGATTAAGCAGCTTGAGACGAAGCATAGTGTGTTGAAGCAGAATGAGACGAAGCAAATTGAGCCGATACTGAGTGTGGTGGCGAAGCCGATTGAGCCGAAACTGAGTGTGGTGGCGAAGCAGATTGAGCTGAAACAGAATGAGACGAAGCAGATTGAGCCGATACAGAGTGTGTCGAAACTGAATGAGACGAAGCAAAATGCGCCGAAACAGATTGAGCCGAAACAGATTGCGATTGAACAGATTGCGATGGGGCAGGATGTCATAGTGCAGGATGCCATGGAGCAGGATGTCATTGAGCAGGATGCCATGGAGCAGGATGCCATGGAGCAGGAGCCAACCGAAGAGCAGTTCCCGAAGCCAGCCCCGATCGGTGGTGCCACTGTAGCGGAAGCGGAGGACAATAACAATGGCATCGAGGACGATCTCCAGTCCATAGTCGTGCCCGGCGAGGACGGAATACGCGAAATTCAGAACCAATGCCACGTGTGTGGCCTCATTCTGAGCAAGCTGGCGCATCTGAAACGCCACATGAAGGCGCACGCCGGAACCAAACCGTTCAAGTGCAACGTGTGCTCGAAGTCGTTCTCCCGCGCGGACAATCTGCGGGCGCACCAAAGGATGCACACGGCGGAGAAGAACTACAAGTGTCCGCTGTGCGACGAACGCTTCAAGCGTGTCGATGCGGCCAAGGCGCACATGGGCTCGGCGCATCGCGACTTCGTGGAGGCCAACTACCACGTGTGCACGGTGTGTGACAACTTCTTCAAGACGGACGAGAAGCTGATCGCGCACATGGAGCTGCACAGGGGCGTCAACAGGCTGGTGTGTGACGTGTGCGGCAAGCAGTTCGTGGGCGTGATGGCGTACGAGGCCCACCTGCAGCGGCACGCGGCCGAGTCGGAACAACCGACCATGTACTCCTGTGCGCACTGTGACAAGAAGTTTTCCAGCAAAGCGTACCTGTTGATGCATATGCGCTACATGATGTCAAACAAATGCTTGGAGTGCAAGTACTGCGGTAAAAAATTTGCACGCCAGAGTGATTTGAAGTCGCACGAAGACTACCATACCGGGATCAAGCCCTTCACCTGCAAGACCTGTGGGAAGAGCTTCCATCGTCAGTGTACACTCGTCGTACACATGCGAACGCACACGGGAGAAAAACCGTTCCAATGTTCGTACTGTCCCAAAAGCTTTTACCAGAAGAACGACATGCTGACGCACGAACGGCGCCATACGGGTGAGCGGTACCAGTGCGAATTTTGTGAGCAAAAGTTTATTCACCTGCACCTGCTGAATTCGCATCTAAAGGTAGTACACAACTATGACGTGGATTGCCGAAAGCGGGGTGTGAAGAAGTTTTTCGACGAACCCGGTCCGACGGTTTTTGCGGAGAAGGAACCGAAGCCCGAGTAG
Protein Sequence: MINKISAFERQDNPRLPDRLCFVCAEQLRIAYGFQQMCDDSYRILLIQLEKQPEPVVPKEEPVIIDVDALGLSETEQDESEQKEIKQLETKHSVLKQNETKQIEPILSVVAKPIEPKLSVVAKQIELKQNETKQIEPIQSVSKLNETKQNAPKQIEPKQIAIEQIAMGQDVIVQDAMEQDVIEQDAMEQDAMEQEPTEEQFPKPAPIGGATVAEAEDNNNGIEDDLQSIVVPGEDGIREIQNQCHVCGLILSKLAHLKRHMKAHAGTKPFKCNVCSKSFSRADNLRAHQRMHTAEKNYKCPLCDERFKRVDAAKAHMGSAHRDFVEANYHVCTVCDNFFKTDEKLIAHMELHRGVNRLVCDVCGKQFVGVMAYEAHLQRHAAESEQPTMYSCAHCDKKFSSKAYLLMHMRYMMSNKCLECKYCGKKFARQSDLKSHEDYHTGIKPFTCKTCGKSFHRQCTLVVHMRTHTGEKPFQCSYCPKSFYQKNDMLTHERRHTGERYQCEFCEQKFIHLHLLNSHLKVVHNYDVDCRKRGVKKFFDEPGPTVFAEKEPKPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101105; iTF_00102513; iTF_00107130; iTF_00095784; iTF_00093609;
90% Identity: -
80% Identity: -