Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:19637634-19640339[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00018 0.0084 16.0 2.2 2 23 380 401 379 401 0.97

2 10 6e-09 2.9e-07 30.0 1.2 1 23 407 429 407 429 0.99

3 10 8.9e-05 0.0042 16.9 0.1 1 23 435 458 435 458 0.95

4 10 0.00072 0.034 14.1 0.7 1 23 467 489 467 489 0.96

5 10 0.0026 0.13 12.3 0.0 2 23 496 517 495 517 0.96

6 10 7.1e-06 0.00034 20.4 1.5 1 21 527 547 527 548 0.96

7 10 1.2e-06 6e-05 22.8 0.9 2 23 556 577 555 577 0.93

8 10 5.2e-06 0.00025 20.8 6.6 1 23 583 605 583 605 0.99

9 10 1.3e-05 0.00063 19.5 2.5 1 23 611 633 611 633 0.99

10 10 0.00051 0.024 14.5 3.3 1 23 638 661 638 661 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00018	0.0084	16.0	2.2	2	23	380	401	379	401	0.97
2	10	6e-09	2.9e-07	30.0	1.2	1	23	407	429	407	429	0.99
3	10	8.9e-05	0.0042	16.9	0.1	1	23	435	458	435	458	0.95
4	10	0.00072	0.034	14.1	0.7	1	23	467	489	467	489	0.96
5	10	0.0026	0.13	12.3	0.0	2	23	496	517	495	517	0.96
6	10	7.1e-06	0.00034	20.4	1.5	1	21	527	547	527	548	0.96
7	10	1.2e-06	6e-05	22.8	0.9	2	23	556	577	555	577	0.93
8	10	5.2e-06	0.00025	20.8	6.6	1	23	583	605	583	605	0.99
9	10	1.3e-05	0.00063	19.5	2.5	1	23	611	633	611	633	0.99
10	10	0.00051	0.024	14.5	3.3	1	23	638	661	638	661	0.98

Sequence Information

Coding Sequence: ATGGAAAGTGTGCTAGATTTCAGCGTTATTTGCCATACCTGTTTAAGTGTAACGCCGAGTACGATATCGGTGAAGAGTACAGATCTTAAGTACAATGTCCCGCTCGCCACAATGATCAACAAAATCAGCGCATTCGAGCGCCAAGACAACCCGAGGCTTCCGGACAGATTGTGTTTCGTGTGTGCGGAACAGCTCCGGATCGCGTACGGCTTTCAGCAGATGTGTGACGATTCGTACCGGATTCTTCTCATCCAATTGGAGAAACAACCGGAGCCAGTAGTACCAAAGGAAGAACCCGTCGTCATCGACGTGGACGCGCTAGGGCTGTCTGAAACTGAGCAGGACGAAAGCGAACAGAAAGAGATTAAGCAGCTTGAGACGAAGCATAGTGTGGCGAAGCAGAATGAGACGAAGCAAATTGAGCCGATACTGAGTGTGGTGGCGAAGCAGATTGAGCCGAAACTGAGCGTGGTGGCGAAGCAGATTGAGCCGAAACAGAATGAGACGAAGCAGATTGAGCCGATACAGAGTGTGTCGAAACTGAATGAGACGAAGCAAAATGCGCCGAAACAGATTGAGCCGAAACAGATTGCGATGGAACCGATTGTGATGGGGCATGATGTCATAGAGCAGGATGCCATGGAGCAGGATGCCATGGAGCAGGATTTCATCGAGCAGGATGCCATGGAGCAGGATGACACGGAACAGTACGACACGGAGCAATATGACACGGAGCAGTACGACACGGATCAGTACGACACAGATCAGTACGACACGGAGCAATACGACACCGAGCAGGATGACACGGAGCAAGATGACACGGAGCAGAATGACACGGAGCAGAATGGCATGGTGCACGAAAATGGCTTTATCTCGCCTAGCACCTCCACTGCACCAATGAGCTCAATGAGCAGTGATGTACGAAAATCAGAACTAAGCGAACTGTTGAACGAAGCCGAATACCTCGAGGAATATCTCATGGCCGATCCCGAAGAGCCAACCGAAGAGCAGTTCCCGAAGCCAGCCCCGATCGGCGGTGCCACTGTAGCGGAAGAGGAAGACAATAACAATGGCATCGAGGACGATCTCCAGTCCATAGTCGTGCCCGGCGAGGATGGAATACGCGAAATTCAGAACCAATGCCACGTGTGCGGGCTCATTCTGAGCAAGCTGGCGCATCTGAAACGCCACATGAAGGCGCACGCCGGAACCAAGCCGTTCAAGTGCAACGTGTGCTCGAAGTCGTTCTCCCGGGCGGACAATCTGCGGGCGCACCAAAGGATGCACACGGCGGAGAAGAACTACAAGTGTCCGCTGTGCGACGAACGCTTCAAGCGTGTCGATGCGGCCAAGGCGCACATGGGCTCGGCGCATCGCGACTTCGTGGAGGCCAACTACCACGTGTGCACGGTGTGTGACAACTTCTTCAAGACGGACGAGAAGCTGATCGCGCACATGGAGCTGCACAAGGGCGTCAACAGGCTGGTGTGTGACGTGTGCGGCAAGCAGTTCGTGGGCATGATGGCGTACGAGGCCCACCTGCAGCGGCACGCGGCCGAGTCGGAACAACCGACCATGTACTCCTGTGCGCACTGTGACAAGAAGTTTTCCAGCAAAGCGTACCTCTTGATGCATATGCGCTACATGATGGCAAACAAATGCTTGGAGTGCAAGTACTGTGGTAAAAAATTTGCACGCCAGAGTGATTTGAAGTCGCACGAAGATTACCATACCGGGATCAAGCCCTTCACCTGCAAGACCTGCGGGAAGAGCTTCCATCGTCAGTGTACGCTCGTCGTGCACATGCGAACGCACACGGGAGAAAAACCGTTCCAATGTTCGTACTGTCCCAAAAGCTTCTACCAGAAGAACGACATGCTGACGCACGAACGGCGCCATACGGGTGAGCGGTACCAGTGTGAATTTTGTGAGCAAAAGTTTATTCACCTGCACCTGCTGAATTCGCATCTGAAGGTAGTACACAACCATAACGTGGATTGCCGAAAGCGGGGTGTGAAGAAGTTTTTCGACGAACCCGGTCCGACGGTTTATGCGGCGAAGGAACCGAAGCCCGAGTAG
Protein Sequence: MESVLDFSVICHTCLSVTPSTISVKSTDLKYNVPLATMINKISAFERQDNPRLPDRLCFVCAEQLRIAYGFQQMCDDSYRILLIQLEKQPEPVVPKEEPVVIDVDALGLSETEQDESEQKEIKQLETKHSVAKQNETKQIEPILSVVAKQIEPKLSVVAKQIEPKQNETKQIEPIQSVSKLNETKQNAPKQIEPKQIAMEPIVMGHDVIEQDAMEQDAMEQDFIEQDAMEQDDTEQYDTEQYDTEQYDTDQYDTDQYDTEQYDTEQDDTEQDDTEQNDTEQNGMVHENGFISPSTSTAPMSSMSSDVRKSELSELLNEAEYLEEYLMADPEEPTEEQFPKPAPIGGATVAEEEDNNNGIEDDLQSIVVPGEDGIREIQNQCHVCGLILSKLAHLKRHMKAHAGTKPFKCNVCSKSFSRADNLRAHQRMHTAEKNYKCPLCDERFKRVDAAKAHMGSAHRDFVEANYHVCTVCDNFFKTDEKLIAHMELHKGVNRLVCDVCGKQFVGMMAYEAHLQRHAAESEQPTMYSCAHCDKKFSSKAYLLMHMRYMMANKCLECKYCGKKFARQSDLKSHEDYHTGIKPFTCKTCGKSFHRQCTLVVHMRTHTGEKPFQCSYCPKSFYQKNDMLTHERRHTGERYQCEFCEQKFIHLHLLNSHLKVVHNHNVDCRKRGVKKFFDEPGPTVYAAKEPKPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104539;
90% Identity: iTF_00101105;
80% Identity: -