Basic Information

Insect: Anopheles maculipalpis
Gene Symbol: -
Assembly: GCA_943734865.1
Location: CALSEK010000098.1:183450-186599[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0011 0.061 13.6 6.2 1 23 236 258 236 258 0.98

2 14 2.1e-06 0.00011 22.2 0.2 1 23 288 310 288 310 0.98

3 14 4.9e-07 2.6e-05 24.2 0.8 1 23 316 338 316 338 0.98

4 14 1.1e-06 5.9e-05 23.1 3.5 1 23 344 366 344 366 0.98

5 14 0.00023 0.012 15.8 0.7 1 19 372 390 372 393 0.95

6 14 1.7e-05 0.00091 19.4 0.8 1 23 399 421 399 421 0.98

7 14 1.9e-07 1e-05 25.5 1.1 1 23 430 452 430 452 0.99

8 14 1e-06 5.6e-05 23.2 0.7 1 23 458 480 458 480 0.99

9 14 0.0089 0.48 10.8 0.4 1 19 487 505 487 506 0.96

10 14 0.00026 0.014 15.7 1.1 1 23 607 629 607 629 0.98

11 14 2.5e-06 0.00013 22.0 1.1 1 23 687 709 687 709 0.97

12 14 2.5e-06 0.00013 22.0 1.2 1 23 715 737 715 737 0.98

13 14 1.5e-05 0.00079 19.6 3.1 1 23 745 767 745 767 0.98

14 14 7.9e-09 4.2e-07 29.9 1.0 1 23 773 795 773 795 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0011	0.061	13.6	6.2	1	23	236	258	236	258	0.98
2	14	2.1e-06	0.00011	22.2	0.2	1	23	288	310	288	310	0.98
3	14	4.9e-07	2.6e-05	24.2	0.8	1	23	316	338	316	338	0.98
4	14	1.1e-06	5.9e-05	23.1	3.5	1	23	344	366	344	366	0.98
5	14	0.00023	0.012	15.8	0.7	1	19	372	390	372	393	0.95
6	14	1.7e-05	0.00091	19.4	0.8	1	23	399	421	399	421	0.98
7	14	1.9e-07	1e-05	25.5	1.1	1	23	430	452	430	452	0.99
8	14	1e-06	5.6e-05	23.2	0.7	1	23	458	480	458	480	0.99
9	14	0.0089	0.48	10.8	0.4	1	19	487	505	487	506	0.96
10	14	0.00026	0.014	15.7	1.1	1	23	607	629	607	629	0.98
11	14	2.5e-06	0.00013	22.0	1.1	1	23	687	709	687	709	0.97
12	14	2.5e-06	0.00013	22.0	1.2	1	23	715	737	715	737	0.98
13	14	1.5e-05	0.00079	19.6	3.1	1	23	745	767	745	767	0.98
14	14	7.9e-09	4.2e-07	29.9	1.0	1	23	773	795	773	795	0.98

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATCGATCAATAAAAATAAGATATTCACCCAACGGTACGGCAACAGTAATAACGATATTTGTCGGCTGTGTTTGAAAAATGAAGCCCACATGGAACCGCTGTTCTATTCGAACCTTTTTCCCAACATTTTACTCACGAAAAAGATATACGATTGCACTTCCATCCAGATAATCTACGAGCGCAACTTGCCGATGTTTGTGTGCAAACTTTGCGCCAACAAGCTGGACGAGTACGTGCGGTTTCGGGACCGGTGCATAGCAAATGATGAATTTCTACGCAATGCTCTGGCGGCATTCGATGCCAACGGTGGAAGCTGTTCGAGTGGGATTAAGATGGAACCGGAAGACACATCGCCACCTCCACCGTTGCCACCGACAGCTCCGACGACGGCAAAGTTTGCCCACTGCCTTGCGGTAACGCCGATGGAACTAAACTGTGCCCTTGTTGCGGCTGCTGCCGTTGCAGCCGGTCACCAGAGCAGCAAGCGCGAGCCACCGGATGTGGAGGAAAGCCATGAAAGATATGGTTCCGGTGCTGTCTCTCCCGACCGATCGAGCTGTGGACGAATGGCAACGGTAGACGAGCTGCCATCCCTGAAACAAACGCACGACGATCGATATCGGAGTGGCGAAGAGGAGGACGATCTACCTGCTGACGATGCGTACGGAGAACCAAACCCCGGTGCCAAGCAGTACGTGTGCGAGGTGTGTTCGAAATCGTTCAGAATCCGCCATCATTTGCTTGTGCATAGGCACACGCACGTGGACAATCATGCAGCGCCGACCAACGGTTTGCTGCACGGTGGATCGGACTTTAATGGCGGCGTAACCGGTAGcgggaaacagtcgtataattgtcccaaatgcgccaaagtgttcgtcaacaagggtaatctgctgaaccatctcgagacgcacacgaacgagaagagctacgcgtgtgatatctgcacgaaaacgttcaagtacaatgtgcagctgcggttgcatatgcgcatccacaccggcgaacggccgcacaagtgcgagatttgtaatcgcggattttcgcaactttcaaatctgcgttcccaccgaaaaactcactccaaaGTCAAAccgtacaaatgccatttatgcctcaaaagcttcaccatgctggacaaccttaccgcgcacagtgcaaaatgtctgaaggacaagttccgctgcacgctctgttcgaaatcgttcgccaaggagggtaacctcctgtcgcacctgcagtcccacaccgatggcattgtggagaagatgttcaagtgtgaaatgtgtccgaaaagtttcaaaaacaaggaggactggaaacggcacgtgcgtgttcatacgggcgaaaaaccgtacacttgcgatatctgctcgaaagggttcgcccaaaaggcgaatctactctcccaccgcaaaacgcacctgaagccaaacgtggtgtacaaatgtgaacgctgtgcgcgtacgtttcgatcccagaaagtcCTCCAGCTACATGTGCCCAAGTGTTCCGGCATTGGTGTGAGTGATGGGACGAGTGTTCCTTCCGCTCCAGCTACACCGGTGTCGGAATCGGTTCCGGATTCTCCGAGTCCGGGAACGGCCGTCACCCAGTCGAACACGGCATCCTCTACCGTGGCTTCGGCAAACGACACGCCCACACTATCGGAAGCTCTATCCGATCTGTTGCGGTACGAAATCGCGTTACGAGCACCGCTGGAACTGCAGCAAATGCTGCTCGGGCACATTGATCGCAAGAAGCCACAAAATGGAACTGGCGGCAAAGCGACCGGACGGCGCTACAGGTGTGATGTGTGCTTCAAGGGCTACTCCCAGTATCCGTCACTGATCAAGCATCGAAAGCTACACTTCAAGGTACCTCCACTGGTAAAGGTTCTGGCGGGTAAGGGAAAGCACGACGCCGACTACGAGGACCACGAGGAACCACGGGATGCGGGATGTGACGAGCATGCGACTGATGGCCGACACCTAgacgggacgacaccaccaccggagccgcacgatccaatcgagcggccgtacagctgtgatatatgcggtaagaactttaaatacaatcgtaacctgaaggtgcacggcaagctgcacataaaagcgaaccgttttaagtgtgacaagtgtaccaccacctttgcacaggcggaagatttgaggcggcatctgaccacccacccgaccgatgccggcaggagcttcagctgcgagtactgctcgaaccggttccgctcgaacgaggacctgaagcggcaccgacgctcccacaccggcgagcggcccttccgctgcccgcactgcccgaaagcgtttacccagcagtcgaaccttcgggcccacgcgaggatccacgagcgCTAG
Protein Sequence: MAEDLSINKNKIFTQRYGNSNNDICRLCLKNEAHMEPLFYSNLFPNILLTKKIYDCTSIQIIYERNLPMFVCKLCANKLDEYVRFRDRCIANDEFLRNALAAFDANGGSCSSGIKMEPEDTSPPPPLPPTAPTTAKFAHCLAVTPMELNCALVAAAAVAAGHQSSKREPPDVEESHERYGSGAVSPDRSSCGRMATVDELPSLKQTHDDRYRSGEEEDDLPADDAYGEPNPGAKQYVCEVCSKSFRIRHHLLVHRHTHVDNHAAPTNGLLHGGSDFNGGVTGSGKQSYNCPKCAKVFVNKGNLLNHLETHTNEKSYACDICTKTFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTMLDNLTAHSAKCLKDKFRCTLCSKSFAKEGNLLSHLQSHTDGIVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHRKTHLKPNVVYKCERCARTFRSQKVLQLHVPKCSGIGVSDGTSVPSAPATPVSESVPDSPSPGTAVTQSNTASSTVASANDTPTLSEALSDLLRYEIALRAPLELQQMLLGHIDRKKPQNGTGGKATGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLAGKGKHDADYEDHEEPRDAGCDEHATDGRHLDGTTPPPEPHDPIERPYSCDICGKNFKYNRNLKVHGKLHIKANRFKCDKCTTTFAQAEDLRRHLTTHPTDAGRSFSCEYCSNRFRSNEDLKRHRRSHTGERPFRCPHCPKAFTQQSNLRAHARIHER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100445;
90% Identity: iTF_00104071;
80% Identity: iTF_00104071;