Basic Information

Insect: Anopheles gambiae
Gene Symbol: -
Assembly: GCF_000005575.2
Location: NT:37846373-37849858[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.01 0.52 10.4 3.9 1 20 152 171 152 174 0.93

2 17 4.5e-05 0.0023 17.8 1.8 2 23 239 260 238 260 0.97

3 17 0.065 3.3 7.8 3.3 1 23 267 290 267 290 0.88

4 17 3.9e-06 0.0002 21.1 3.6 1 23 304 326 304 326 0.97

5 17 0.025 1.3 9.2 2.0 3 23 334 355 332 355 0.96

6 17 2.9 1.5e+02 2.7 0.3 1 23 462 485 462 485 0.90

7 17 7.9e-07 4e-05 23.3 1.2 1 23 518 540 518 540 0.92

8 17 1.2e-05 0.00062 19.6 1.7 1 23 546 569 546 569 0.98

9 17 0.054 2.7 8.1 2.1 1 23 578 601 578 601 0.94

10 17 0.0014 0.071 13.1 3.0 1 23 779 801 779 801 0.95

11 17 0.0087 0.44 10.6 2.3 1 23 807 830 807 830 0.97

12 17 0.016 0.79 9.8 0.8 1 23 841 864 841 864 0.97

13 17 8.6 4.4e+02 1.2 1.2 1 21 889 909 889 912 0.77

14 17 8.7 4.4e+02 1.2 4.4 2 23 928 949 927 949 0.94

15 17 4.2e-06 0.00022 21.0 2.3 1 23 974 996 974 996 0.98

16 17 0.00083 0.042 13.8 0.4 1 23 1002 1025 1002 1025 0.96

17 17 0.00063 0.032 14.2 1.1 2 23 1040 1062 1040 1062 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.01	0.52	10.4	3.9	1	20	152	171	152	174	0.93
2	17	4.5e-05	0.0023	17.8	1.8	2	23	239	260	238	260	0.97
3	17	0.065	3.3	7.8	3.3	1	23	267	290	267	290	0.88
4	17	3.9e-06	0.0002	21.1	3.6	1	23	304	326	304	326	0.97
5	17	0.025	1.3	9.2	2.0	3	23	334	355	332	355	0.96
6	17	2.9	1.5e+02	2.7	0.3	1	23	462	485	462	485	0.90
7	17	7.9e-07	4e-05	23.3	1.2	1	23	518	540	518	540	0.92
8	17	1.2e-05	0.00062	19.6	1.7	1	23	546	569	546	569	0.98
9	17	0.054	2.7	8.1	2.1	1	23	578	601	578	601	0.94
10	17	0.0014	0.071	13.1	3.0	1	23	779	801	779	801	0.95
11	17	0.0087	0.44	10.6	2.3	1	23	807	830	807	830	0.97
12	17	0.016	0.79	9.8	0.8	1	23	841	864	841	864	0.97
13	17	8.6	4.4e+02	1.2	1.2	1	21	889	909	889	912	0.77
14	17	8.7	4.4e+02	1.2	4.4	2	23	928	949	927	949	0.94
15	17	4.2e-06	0.00022	21.0	2.3	1	23	974	996	974	996	0.98
16	17	0.00083	0.042	13.8	0.4	1	23	1002	1025	1002	1025	0.96
17	17	0.00063	0.032	14.2	1.1	2	23	1040	1062	1040	1062	0.94

Sequence Information

Coding Sequence: atgGAGCCAGAGCAAGAGCCCGAACCGATTGGAGAAGATGATCCAGTGGATGTCCCGAACTCGAATCCCGAGACATACTGCCGGTTTTGCTTCTCGGAGAACGAAGTAGAGCCACTGTTTGCCGCGAATGGTACGCAGGCCAGTACCGAACTGCTGCAACGCATCCAAGAGTGCATCGGCATCAAGCTGACACGGAAGGAATACTGCCCCAGCGCCATTTGCTGGTCGTGTACGCTCACGCTGGAGGAGTTCCAATGCTTTCGCAAACGTTGCTTGAAATTCGACACACTGGTGCGGCGCTTGCTGCCGTCGGTGAAATCGGAACCGAGCCATCGCACTGCCACACCGACGACTGCGGGgcagaaggagaaaaaaattaCCAGCAAGCAGCAGCCGGCGGCAAATGTGGCCGATTCGGAGAAAAACAATGGTGGGCCGTCGACTGCGTTGAAGTTCAAATGCCAGTTTTGTCCGCGCAGCTTCAAGCACCGAATGTATTTGGATCAGCATCTCTGGAAGCATCGGGACCGGATCGCGGCGGATGCAGCCTCCGCCGCCGGCGCGGGCACTAAAAAAATTCCTCACGTAAATGGAAACGGCAGCTCAGCGGTAAAGATTAAATCGGAACAAGCTGCGCAACAGAAATCCGCTGAACAGAAAGCTCctcctgctgcagctgctcccGCTGGTGGCGGTGCTACCGACCGGCCAATTAGCTGTGAATACTGTCCCCGCAAGTTTACCCGCCGGATGTACTACATGCAGCATCTTCGCCGGCACAAACCGGACGAGCGGCTGTTCCGCTGCCGGCATTGTCCGCGCAGCTTCACGTCGCAGCTGCGACGTACCGGGCACGAGCGAAAGATACACGGCCAGCTGAGCAACCCAAAGTCGGAGCAAAAGGACACCTTCTCCTGTCCGAAGTGTTCGCGCGTGTTTAAGCACCGGTCGTCGTTGCGGATGCATATGCTGAACCACGACGGACAGCTGCCGTACGGGTGCGACATCTGCAACTGTCGCTTTTACAGCGTCAGCTATCTGGCCCTGCACAAGAAGCGCTACCATGGCCCGAACGCGGCCCGGTCGATGACGAACGGTACCTCCATTCCGTGCCATTACTGTTCGCGCTGGTTTCTGCGCGAGTGCGACCGGTCTAGCCACATCAAGCAGATGCACGCGGACATGCACGCGAGCAAAGAGTCAGCGGCTGGCTTTAACCAACTGCTCGAAGACTGCCCCCCGGCAGACAGTGAGGGACTGACCGATCCGGAAATGTTGCCGCCAAACGTGCACGAGCCGATGATGGTGATCAAGGAGGAGGAACCGGACGGGCACGAAGCGGCGGCCTCCAATTCGGTAGCGAACAATCCGGACACGCTGCAGTTCTACTGCTACTCCTGTGCCATGCCGTTCGACACGGAGGACATGTTCTCGGAGCATCTGGACGATCAGCATCCGTTCGGGGGCGAACAGCTGATGGATCAGCTGCAGTCGGCTTCCCCGTTCGgggagcaacagcagcaggagcagcaggacCAGGATGCGAACGTGTTCAAATGTCCGTACTGTCCGAAAACGTTCACGCGCAAATGGAGTTTGACGCAGCACTTGCCGACGCACATCGCGAAGAAAGGATACCAGTGCGAATACTGTCCTGCGATCTTTACGCGCAACGAGTACTTGCGCACGCACCGGAAGCGCAAACATCCGAATCTGCCAGAGACGGGCGCGCACAAATGCAGCTACTGTCCGCGCATGTTCAACATGGTGCGATACAAAAAGGTGCACGAACGGATCGCACACATCAAGAAGGGAGACATCCTGCCGGAAGGGGACGACACGGAGAGCAGTGAGGTGGCGGCAATCAACAGTTTGCAGGTTGAGAAGCAGCTGGACGAAAGTAGCAACAGCCTGGCACCGGAGCTACCTTCCCGTGCGTCGGACAGTTTCGATCAAGCGTCCAACGACGCGCCCAGTGTCGCTTCGGTGCAGAACTACGCCGATCTGGAAGCATCCTCGCGGCTCGCCGTTGTGCTGGAACGGTTGCCGGCACAGGAGCTGGAACAGTACCGTTGGCAGCTGGAGCACTACGCAAGTTTGCCACCCGTCATCGAAATCAAGCGGGAACTGTTGGATCCCCAGTATGGTGATATCGAGGGCGAGGGCTTCAATGACAACGCTGTTTATGATGGTAATAATTACGACGATGAGCATgaggtggaggaggaagaTGCTGCTAGCAATGACGCGGAGGATTCGTTTCAGCCggaccaatcgaacgattCGGGAAAGCAGTTGCTGAAGCGAAAGCGTACCAAGTTTGGCATCACGCTTCATCCCTGTCCGCACTGCTCGAAACTGTTCAAAACCCGCACAGCGCTCCGGCTGCACGCGCTTTACCACAGTGGCGATCTGCCGCACCGGTGTGACGAGTGTGGCGTACAGTTTATGCGCTACAACCAGCTCGTGTATCACACGAACCGGTACCATGGGGCGAACAGCGCTACGATGGCAGCCCGGTACAGCTGCGACTACTGTCCGCGCATTTTCCTGCGCAAGCAGGACCGCACCACGCACCAGCTGATGGTGCACGCGCGCGATCAGGCGAATGCGATCGATAAATCGCCGGCGCTCACAATcgcgaagaaaacgaaacgcaaAGATTACGTGTGCCGCGTGTGCGATGCGGAGTTCGAGAAGTATCGGCGGTGCGTCCGGCACATCACACTCATCCACGCGGGCTCGGATGGTGAACCGGAGTGTCGACCGATCAAGCTATGCCACTGCAGCATCTGCAGCGGCATCTACAAGAAGCGCGACGACTGGCACGAGCATCTGAACGACCATCCGAGCGTTCGGCCGCACCACTGCGAGCAGTGCATCAGGAGGCGCAGGAAAGCGTCCAGCCGGAAGCAGGTGCACCGCTGCTCCTACTGCCCGAAAGCGTTCGAGCACAAGCCGAACCTGGCGTCGCATCTGCGCATACACAAGCAGCAGCTGCGGTTCCCGTGCAGCGAGTGCGGCGTAATGTACGACCGGTATCGCGATCTACTGACGCACCAGAGCCGCTACCATCCGGAGAATCAGGACGATTCGGTTGCGCGTGAGCCGCTGCCAAAGTGCAACTTTTGTCCGCGTGTGTTCACCCGGCAGCGGGATGTCAAGTATCACCAGGAGCAGGTACATGCGGATCAAGTGATACCTGCTGGCGACGCGGAAGCTACTAACGAACCGGAGGAGGATGAAGAACCGGACGAACAGCAGGAAAATGAGGGTGATGGTTTGATGACATTCGGGTTTGGGCCGGAGATGTTTCCCGAGCCCGACGTGCAAGAGGACCCGGTGTTTAATGCAGCTGACCTGCCGATCAAATCGGAACCAGATCCCGATCCCCCGTCACCAAGCAGTAATATGATGATTGATTGA
Protein Sequence: MEPEQEPEPIGEDDPVDVPNSNPETYCRFCFSENEVEPLFAANGTQASTELLQRIQECIGIKLTRKEYCPSAICWSCTLTLEEFQCFRKRCLKFDTLVRRLLPSVKSEPSHRTATPTTAGQKEKKITSKQQPAANVADSEKNNGGPSTALKFKCQFCPRSFKHRMYLDQHLWKHRDRIAADAASAAGAGTKKIPHVNGNGSSAVKIKSEQAAQQKSAEQKAPPAAAAPAGGGATDRPISCEYCPRKFTRRMYYMQHLRRHKPDERLFRCRHCPRSFTSQLRRTGHERKIHGQLSNPKSEQKDTFSCPKCSRVFKHRSSLRMHMLNHDGQLPYGCDICNCRFYSVSYLALHKKRYHGPNAARSMTNGTSIPCHYCSRWFLRECDRSSHIKQMHADMHASKESAAGFNQLLEDCPPADSEGLTDPEMLPPNVHEPMMVIKEEEPDGHEAAASNSVANNPDTLQFYCYSCAMPFDTEDMFSEHLDDQHPFGGEQLMDQLQSASPFGEQQQQEQQDQDANVFKCPYCPKTFTRKWSLTQHLPTHIAKKGYQCEYCPAIFTRNEYLRTHRKRKHPNLPETGAHKCSYCPRMFNMVRYKKVHERIAHIKKGDILPEGDDTESSEVAAINSLQVEKQLDESSNSLAPELPSRASDSFDQASNDAPSVASVQNYADLEASSRLAVVLERLPAQELEQYRWQLEHYASLPPVIEIKRELLDPQYGDIEGEGFNDNAVYDGNNYDDEHEVEEEDAASNDAEDSFQPDQSNDSGKQLLKRKRTKFGITLHPCPHCSKLFKTRTALRLHALYHSGDLPHRCDECGVQFMRYNQLVYHTNRYHGANSATMAARYSCDYCPRIFLRKQDRTTHQLMVHARDQANAIDKSPALTIAKKTKRKDYVCRVCDAEFEKYRRCVRHITLIHAGSDGEPECRPIKLCHCSICSGIYKKRDDWHEHLNDHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCSECGVMYDRYRDLLTHQSRYHPENQDDSVAREPLPKCNFCPRVFTRQRDVKYHQEQVHADQVIPAGDAEATNEPEEDEEPDEQQENEGDGLMTFGFGPEMFPEPDVQEDPVFNAADLPIKSEPDPDPPSPSSNMMID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095206;
90% Identity: iTF_00095815; iTF_00093645; iTF_00101137; iTF_00107156; iTF_00104569;
80% Identity: -