Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:36993293-36997204[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.011 0.51 10.4 3.9 1 20 152 171 152 174 0.93

2 17 4.7e-05 0.0023 17.8 1.8 2 23 239 260 238 260 0.97

3 17 0.068 3.2 7.9 3.3 1 23 267 290 267 290 0.88

4 17 4.1e-06 0.0002 21.1 3.6 1 23 304 326 304 326 0.97

5 17 0.026 1.2 9.2 2.0 3 23 334 355 332 355 0.96

6 17 3 1.4e+02 2.7 0.3 1 23 462 485 462 485 0.90

7 17 8.2e-07 3.9e-05 23.3 1.2 1 23 515 537 515 537 0.92

8 17 1.3e-05 0.0006 19.6 1.7 1 23 543 566 543 566 0.98

9 17 0.056 2.7 8.1 2.1 1 23 575 598 575 598 0.94

10 17 0.0014 0.069 13.1 3.0 1 23 777 799 777 799 0.95

11 17 0.009 0.43 10.6 2.3 1 23 805 828 805 828 0.97

12 17 0.016 0.77 9.8 0.8 1 23 839 862 839 862 0.97

13 17 9 4.3e+02 1.2 1.2 1 21 887 907 887 910 0.77

14 17 9 4.3e+02 1.2 4.4 2 23 926 947 925 947 0.94

15 17 4.4e-06 0.00021 21.0 2.3 1 23 972 994 972 994 0.98

16 17 0.00086 0.041 13.8 0.4 1 23 1000 1023 1000 1023 0.96

17 17 0.00066 0.031 14.2 1.1 2 23 1038 1060 1038 1060 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.011	0.51	10.4	3.9	1	20	152	171	152	174	0.93
2	17	4.7e-05	0.0023	17.8	1.8	2	23	239	260	238	260	0.97
3	17	0.068	3.2	7.9	3.3	1	23	267	290	267	290	0.88
4	17	4.1e-06	0.0002	21.1	3.6	1	23	304	326	304	326	0.97
5	17	0.026	1.2	9.2	2.0	3	23	334	355	332	355	0.96
6	17	3	1.4e+02	2.7	0.3	1	23	462	485	462	485	0.90
7	17	8.2e-07	3.9e-05	23.3	1.2	1	23	515	537	515	537	0.92
8	17	1.3e-05	0.0006	19.6	1.7	1	23	543	566	543	566	0.98
9	17	0.056	2.7	8.1	2.1	1	23	575	598	575	598	0.94
10	17	0.0014	0.069	13.1	3.0	1	23	777	799	777	799	0.95
11	17	0.009	0.43	10.6	2.3	1	23	805	828	805	828	0.97
12	17	0.016	0.77	9.8	0.8	1	23	839	862	839	862	0.97
13	17	9	4.3e+02	1.2	1.2	1	21	887	907	887	910	0.77
14	17	9	4.3e+02	1.2	4.4	2	23	926	947	925	947	0.94
15	17	4.4e-06	0.00021	21.0	2.3	1	23	972	994	972	994	0.98
16	17	0.00086	0.041	13.8	0.4	1	23	1000	1023	1000	1023	0.96
17	17	0.00066	0.031	14.2	1.1	2	23	1038	1060	1038	1060	0.94

Sequence Information

Coding Sequence: atgGAGCCAGAGCAAGAGCCCGAACCGATCGGAGAAGATGATCCAGTGGATGTTCCGAACTCGAATCCCGAGACATACTGCCGGTTTTGCTTCTCGGAGAACGAAGTAGAGCCACTGTTTGCTGCGAATGGCACGCAGGCCAGTGCCGAACTGCTGCAACGCATCCAGGAGTGCATCGGCATCAAGCTGACACGGAAGGAATACTGCCCCAGCGCCATTTGCTGGTCGTGTACGCTCACGCTGGAGGAGTTCCAATGCTTTCGCAAACGTTGCTTGAAATTCGACACACTGGTGCGGCGCTTGCTGCCGACGGTGAAATCGGAACCGAGCCATCGCACTGCCACACCGACGAATGCGGGGCAGAAGGTGAAAAAAATTACCAGCAAGCAGCAGCCGGCGGCAAATGTGGCCGATTCGGAGAAAAACAATGGTGGGCCGTCGACTGCGTTGAAGTTCAAATGCCAGTTTTGTCCGCGCAGCTTCAAGCACCGAATGTATTTGGATCAGCATCTCTGGAAGCATCGGGACCGGATCGCGGCGGATGCAGTCTCCACCGCCGGCGCGGGCACTAAAAAAATTCCTCACGTAAATGGAAACGGCAGCTCAGCGGTAAAGATTAAATCGGAACAAGCTGCGCAACAGAAATCCGCTGAGCAGAAAGCTCctcctgctgcagctgctcccgctggtggtggtgctaccGATCGGCCAATTAGCTGTGAATACTGTCCCCGCAAGTTTACCCGCCGGATGTACTACATGCAGCATCTTCGCCGGCACAAACCGGACGAGCGGCTGTTCCGCTGCCGGCATTGCCCGCGCAGCTTCACGTCGCAGCTGCGACGTACCGGGCACGAGCGAAAGATACACGGCCAGCTGAGCAACCCAAAGTCGGAGCAAAAGGACACCTTCTCCTGTCCGAAGTGTTCGCGCGTGTTTAAGCACCGGTCGTCGTTGCGGATGCATATGCTGAACCACGACGGACAGCTGCCGTACGGGTGCGACATTTGCAACTGTCGCTTTTACAGCGTCAGCTATCTGGCTCTGCACAAGAAGCGCTACCATGGCCCGAACGCGGCCCGGTCCATGACGAACGGTACCTCCATTCCGTGCCATTACTGTTCGCGCTGGTTTTTGCGCGAGTGTGACCGGTCGAGCCACATCAAGCAGATGCACGCGGACATGCACGCGAGCAAAGAGTCAGCGGCCGGGTTTAACCAACTGCTCGAAGACTGCCCCCCGGCAGACAGTGAGGGACTGACCGATCCGGAAATGTTGCCGCCAAACGTGCACGAGCCGATGATGGTGATCAAGGAGGAGGAACCGGACGGGCACGAAGCGGCGGCTTCTAATTCGGTAGCGAACAATCCGGACACGCTGCAGTTCTACTGCTACTCCTGTGCCATGCCGTTCGACACGGAGGACATGTTCTCGGAGCATCTGGACGATCAGCATCCGTTCGGGGGCGAACAGCTGATGGATCAGCTGCAGTCGGCTTCCCCGTTCggggagcaacagcagcaggaccAAGATGCGAACGTGTTCAAATGTCCGTACTGTCCGAAAACGTTCACGCGCAAATGGAGTTTGACGCAGCACTTGCCGACGCACATCGCGAAGAAAGGATACCAGTGCGAATACTGTCCTGCGATCTTTACGCGCAACGAGTACTTGCGCACGCACCGGAAGCGCAAACATCCGAATCTGCCAGAGACGGGCGCGCACAAATGCAGCTACTGTCCGCGCATGTTCAACATGGTGCGATACAAAAAGGTGCACGAACGGATCGCACACATCAAGAAGGGAGACATCCTGCCGGAAGGGGACGACACGGAGAGCAGTGAGGTGGCGGCAATCAACAGTTTGCAGGTTGAGAAGCAGCTGGACGAAAGTAGCAACAGCCTGGCACCGGAGCTACCTTCCCGTGCGTCGGACAGTTTCGATCAAGCGTCCAACGACGCGCCCAGTGTCGCTTCCGTGCAGAACTACGCCGATCTGGAAGCATCCTCGCGGCTCGCCGTTGTGCTGGAACGGTTGCCGGCGCATGAGCTGGAACAGTACCGTTGGCAGCTGGAGCACTACGCAAGTATGCCACCAGTCATCGAAATCAAGCGGGAACTGTTGGATCCCCAGTATGGTGATATCGAGGGCGAGGGCGAGGGCTTCAATGACAACGCTGTTTATGATGGTAATAATTACGACGATGAGcaggtggaggaggaagaTGCTGCTAGCAACGACGCGGAGGATTCGTTTCAGccggaccaatcgaacgattCGGGAAAGCAGTTGCTGAAGCGAAAGCGTACCAAGTTTGGCATCACGCTTCATCCCTGTCCGCACTGCTCGAAACTGTTCAAAACCCGCACAGCGCTCCGGCTGCACGCGCTTTACCACAGTGGCGATCTGCCGCACCGGTGTGACGAGTGTGGCGTACAGTTTATGCGCTACAACCAGCTCGTGTATCACACGAACCGGTACCATGGGGCGAACAGCGCTACGATGGCAGCCCGGTACAGCTGCGACTACTGTCCGCGCATTTTCCTGCGCAAGCAGGACCGCACCACGCACCAGCTGATGGTGCACGCGCGCGATCAGGCGAATGCGATCGATAAATCGCCGGCGCTCACAATcgcgaagaaaacgaaacgcaAAGATTACGTGTGTCGCGTGTGCGATGCGGAGTTCGAGAAGTATCGGCGGTGTGTTCGGCACATCACACTCATCCACGCGGGCTCGGATGGTGAACCGGAGTGTCGACCGATCAAGCTGTGCCACTGCAGCATCTGCAGCGGCATCTACAAGAAGCGCGACGACTGGCACGAGCATCTGAACGACCATCCGAGCGTGCGGCCGCACCACTGCGAGCAGTGCATCCGGAGGCGCAGGAAAGCGTCCAGCCGGAAGCAGGTGCACCGCTGCTCCTACTGCCCGAAAGCGTTCGAGCACAAGCCGAACCTGGCGTCGCATCTGCGCATACACAAGCAGCAGCTGCGGTTCCCGTGCAGCGAGTGCGGCGTAATGTATGACCGGTATCGCGATCTGCTGACGCACCAGAGCCGCTACCATCCGGAGAATCAAGACGATTCGGTTGCGCGTGAGCCGCTGCCAAAGTGCAACTTTTGTCCGCGTGTGTTCACCCGGCAGCGGGATGTCAAGTATCACCAGGAGCAGGTACATGCGGATCAAGTGATACCTGCTGGCGACGCGGAAGCTACTAACGAACCGGAGGAGGATGAAGAACCGGACGAGCAGCAGGAAAATGAGGGTGATGGTTTGATGACATTCGGGTTTGGGCCGGAGATGTTTCCCGAGCCCGACGTGCAAGAGGACCCGGTGTTTAATGCAGCTGACCTGCCGATCAAATCGGAACCGGATCCCGATCCTCCGTCACCAAGCAGTAATATGATGATTGATTGA
Protein Sequence: MEPEQEPEPIGEDDPVDVPNSNPETYCRFCFSENEVEPLFAANGTQASAELLQRIQECIGIKLTRKEYCPSAICWSCTLTLEEFQCFRKRCLKFDTLVRRLLPTVKSEPSHRTATPTNAGQKVKKITSKQQPAANVADSEKNNGGPSTALKFKCQFCPRSFKHRMYLDQHLWKHRDRIAADAVSTAGAGTKKIPHVNGNGSSAVKIKSEQAAQQKSAEQKAPPAAAAPAGGGATDRPISCEYCPRKFTRRMYYMQHLRRHKPDERLFRCRHCPRSFTSQLRRTGHERKIHGQLSNPKSEQKDTFSCPKCSRVFKHRSSLRMHMLNHDGQLPYGCDICNCRFYSVSYLALHKKRYHGPNAARSMTNGTSIPCHYCSRWFLRECDRSSHIKQMHADMHASKESAAGFNQLLEDCPPADSEGLTDPEMLPPNVHEPMMVIKEEEPDGHEAAASNSVANNPDTLQFYCYSCAMPFDTEDMFSEHLDDQHPFGGEQLMDQLQSASPFGEQQQQDQDANVFKCPYCPKTFTRKWSLTQHLPTHIAKKGYQCEYCPAIFTRNEYLRTHRKRKHPNLPETGAHKCSYCPRMFNMVRYKKVHERIAHIKKGDILPEGDDTESSEVAAINSLQVEKQLDESSNSLAPELPSRASDSFDQASNDAPSVASVQNYADLEASSRLAVVLERLPAHELEQYRWQLEHYASMPPVIEIKRELLDPQYGDIEGEGEGFNDNAVYDGNNYDDEQVEEEDAASNDAEDSFQPDQSNDSGKQLLKRKRTKFGITLHPCPHCSKLFKTRTALRLHALYHSGDLPHRCDECGVQFMRYNQLVYHTNRYHGANSATMAARYSCDYCPRIFLRKQDRTTHQLMVHARDQANAIDKSPALTIAKKTKRKDYVCRVCDAEFEKYRRCVRHITLIHAGSDGEPECRPIKLCHCSICSGIYKKRDDWHEHLNDHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCSECGVMYDRYRDLLTHQSRYHPENQDDSVAREPLPKCNFCPRVFTRQRDVKYHQEQVHADQVIPAGDAEATNEPEEDEEPDEQQENEGDGLMTFGFGPEMFPEPDVQEDPVFNAADLPIKSEPDPDPPSPSSNMMID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095206;
90% Identity: iTF_00102538;
80% Identity: -