Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027928.1:39546686-39550168[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.011 0.56 10.5 3.9 1 20 152 171 152 174 0.93

2 17 4.8e-05 0.0025 17.9 1.8 2 23 239 260 238 260 0.97

3 17 0.069 3.6 7.9 3.3 1 23 267 290 267 290 0.88

4 17 4.1e-06 0.00022 21.2 3.6 1 23 304 326 304 326 0.97

5 17 0.026 1.4 9.2 2.0 3 23 334 355 332 355 0.96

6 17 3 1.6e+02 2.7 0.3 1 23 462 485 462 485 0.90

7 17 8.3e-07 4.3e-05 23.4 1.2 1 23 518 540 518 540 0.92

8 17 1.3e-05 0.00067 19.7 1.7 1 23 546 569 546 569 0.98

9 17 0.057 3 8.2 2.1 1 23 578 601 578 601 0.94

10 17 0.0015 0.077 13.2 3.0 1 23 753 775 753 775 0.95

11 17 0.0091 0.48 10.7 2.3 1 23 781 804 781 804 0.97

12 17 0.016 0.86 9.9 0.8 1 23 815 838 815 838 0.97

13 17 9.1 4.8e+02 1.2 1.2 1 21 863 883 863 886 0.77

14 17 9.2 4.8e+02 1.2 4.4 2 23 902 923 901 923 0.94

15 17 4.5e-06 0.00023 21.1 2.3 1 23 948 970 948 970 0.98

16 17 0.00087 0.046 13.9 0.4 1 23 976 999 976 999 0.96

17 17 0.00067 0.035 14.3 1.1 2 23 1014 1036 1014 1036 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.011	0.56	10.5	3.9	1	20	152	171	152	174	0.93
2	17	4.8e-05	0.0025	17.9	1.8	2	23	239	260	238	260	0.97
3	17	0.069	3.6	7.9	3.3	1	23	267	290	267	290	0.88
4	17	4.1e-06	0.00022	21.2	3.6	1	23	304	326	304	326	0.97
5	17	0.026	1.4	9.2	2.0	3	23	334	355	332	355	0.96
6	17	3	1.6e+02	2.7	0.3	1	23	462	485	462	485	0.90
7	17	8.3e-07	4.3e-05	23.4	1.2	1	23	518	540	518	540	0.92
8	17	1.3e-05	0.00067	19.7	1.7	1	23	546	569	546	569	0.98
9	17	0.057	3	8.2	2.1	1	23	578	601	578	601	0.94
10	17	0.0015	0.077	13.2	3.0	1	23	753	775	753	775	0.95
11	17	0.0091	0.48	10.7	2.3	1	23	781	804	781	804	0.97
12	17	0.016	0.86	9.9	0.8	1	23	815	838	815	838	0.97
13	17	9.1	4.8e+02	1.2	1.2	1	21	863	883	863	886	0.77
14	17	9.2	4.8e+02	1.2	4.4	2	23	902	923	901	923	0.94
15	17	4.5e-06	0.00023	21.1	2.3	1	23	948	970	948	970	0.98
16	17	0.00087	0.046	13.9	0.4	1	23	976	999	976	999	0.96
17	17	0.00067	0.035	14.3	1.1	2	23	1014	1036	1014	1036	0.94

Sequence Information

Coding Sequence: ATGGAGCCAGAGCAAGAGCCCGAACCGATCGGAGAAGATGATCCAGTGGATGTCCCGAACTCGAATCCCGAGACATACTGCCGGTTTTGCTTCTCGGAGAACGAAGTAGAGCCACTGTTTGCCGCGAATGGCACGCAGGCCAGTGCCGAACTGCTGCAACGCATCCAAGAGTGCATCGGCATCAAGCTGACACGGAAGGAATACTGCCCCAGCGCCATTTGCTGGTCGTGTACGCTCACGCTGGAGGAGTTCCAATGCTTTCGCAAACGTTGCTTGAAATTCGACACACTGGTGCGGCGCTTGCTGCCGACGGTGAAATCGGAACCGAGCCATCGCACTGCCACACCGACGACTGCGGGGCAGAAGGAGAAAAAAATTACCAGCAAGCAGCAGCCGGCGGCAAATGTGGCCGATTCGGAGAAAAACAATGGTGGGCCGTCGACTGCGTTAAAGTTCAAATGCCAGTTTTGTCCGCGCAGCTTCAAGCACCGAATGTATTTGGATCAGCATCTCTGGAAGCATCGGGACCGGATCGCGGCGGATGCAGCCTCCGCCGCCGGCGCGGGCACTAAAAAAATTCCTCACGTAAATGGAAACGGCAGCTCAGCGGTAAAGATTAAATCGGAACAAGCTGCGCAACAGAAATCCGCTGAGCAGAAAGCTCCTCCTGCTGCAGCTGCTCCCGCTGGTGGCGGTGCTACCGATCGGCCAATTAGCTGTGAATACTGTCCCCGCAAGTTTACCCGCCGGATGTACTACATGCAGCATCTTCGCCGGCACAAACCGGACGAGCGGCTGTTCCGCTGCCGGCATTGCCCGCGCAGCTTCACGTCACAGCTGCGACGTACCGGGCACGAGCGAAAGATACACGCCCAGCTGAGCAACCCAAAGTCGGAGCAAAAGGACACCTTCTCATGTCCGAAGTGTTCGCGCGTGTTTAAGCACCGGTCGTCGTTGCGGATGCATATGCTGAACCACGACGGACAGCTGCCGTACGGGTGCGACATTTGCAACTGTCGCTTTTACAGCGTCAGCTATCTGGCCCTGCACAAGAAGCGCTACCATGGCCCGAACGCGGCCCGGTCCATGACGAACGGTACCTCCATTCCATGCCATTACTGTTCGCGCTGGTTTTTGCGCGAGTGCGACCGGTCGAGCCACATCAAGCAGATGCACGCGGACATGCACGCGAGCAAAGAGTCAGCGGCCGGGTTTAACCAACTGCTCGAAGACTGCCCCCCGGCAGACAGTGAGGGACTGACCGATCCGGAAATGTTGCCGCCAAACGTGCACGAGCCGATGATGGTGATCAAGGAGGAGGAACCGGACGGGCACGAAGCGGCGGCTTCCAATTCGGTAGCGAACAATCCGGACACGCTGCAGTTCTACTGCTACTCCTGTGCCATGCCGTTCGACACGGAGGACATGTTCTCGGAGCATCTGGACGATCAGCATCCGTTCGGGGGCGAACAGCTGATGGATCAGCTGCAGTCGGCTTCCCCGTTCGGGGAGCAACAGCAGCAGGAGCAGCAGGACCAGGATGCGAACGTGTTCAAATGTCCGTACTGTCCGAAAACGTTCACGCGCAAATGGAGTTTGACGCAGCACTTGCCGACGCACATCGCGAAGAAAGGATACCAGTGCGAATACTGTCCTGCGATCTTTACGCGCAACGAGTACTTGCGCACGCACCGGAAGCGCAAACATCCGAATCTGCCAGAGACGGGGGCGCACAAATGCAGCTACTGTCCGCGCATGTTCAACATGGTGCGATACAAAAAGGTGCACGAACGGATCGCACACATCAAGAAGGGAGACATCCTGCCGGAAGGGGACGACACGGAGAGCAGTGAGGTGGCGGCAATCAATAGTTTGCAGGTTGAGAAGCAGCTGGACGAAAGTAGCAACAGCCTGGCACCGGAGCTACCTTCCCGTGCATCGGACAGTTTCGATCAAGCGTCCAACGACGCGCCCAGTGTCGCTTCCGTGCATAACTACGCCGATCTGGAAGCATCCTCGCGGCTCGCCGTTGTGCTGGAACGGTTGCCTGCACAGGAGCTGGAACAGTACCGTTGGCAGCTGGAGCACTACGCAAGTTTGCCACCCGTCATCGAAATCAAGCGGGAACTGTTGGATCCCCAGTACGGCGATATCGAGGGCGAGGGCTTCAATGACAACGCTGTTTATGATGACGAAACGAACGATTCGGGAAAGCAGCTGCTGAAGCGAAAGCGTACCAAGTTTGGCATCACGCTTCATCCCTGTCCGCACTGCTCGAAACTGTTCAAAACCCGCACAGCGCTCCGGCTGCACGCGCTTTACCACAGTGGCGATCTGCCGCACCGGTGTGACGAGTGTGGCGTACAGTTTATGCGCTACAACCAGCTCGTGTATCACACGAACCGGTACCATGGGGCGAACAGCGCTACGATGGCAGCCCGGTACAGCTGCGACTACTGTCCGCGCATTTTCCTGCGCAAGCAGGACCGCACCACGCACCAGCTGATGGTGCACGCGCGCGATCAGGCGAATGCGATCGATAAATCGCCGGCGCTCACAATCGCGAAGAAAACGAAACGCAAAGATTACGTGTGCCGCGTGTGCGATGCGGAGTTCGAGAAGTATCGGCGGTGCGTCCGGCACATCACGCTCATCCACGCGGGCTCGGATGGTGAACCGGAGTGTCGACCGATCGAGCTGTGCCACTGCAGCATCTGCAGCGGCATCTACAAGAAGCGCGACGACTGGCACGAGCATCTGAACGACCATCCGAGCGTGCGGCCGCACCACTGCGAGCAGTGCATCCGGAGGCGCAGGAAAGCGTCCAGCCGGAAGCAGGTGCACCGCTGCTCCTACTGCCCGAAAGCGTTCGAGCACAAGCCGAACCTGGCGTCGCATCTGCGCATACACAAGCAGCAGCTGCGGTTCCCGTGCAGCGAGTGCGGCGTAATGTACGACCGGTATCGCGATCTGCTGACGCACCAGAGCCGCTACCATCCGGAGAATCAGGACGATTCGGTTGCGCGTGAGCCGCTGCCAAAGTGCAACTTTTGTCCGCGTGTGTTCACCCGGCAGCGGGATGTCAAGTATCACCAGGAGCAGGTACATGCGGATCAAGTGATACCTGCTGGCGACGCGGAAGCTACTAACGAACCGGAGGAGGATGAAGAACCGGACGAGCAGCAGGAAAATGAGGGTGATGGTTTGATGACATTCGGGTTTGGGCCGGAGATGTTTCCCGAGCCCGACGTGCAAGAGGACCCGGTTAATATGATGATTGATTGA
Protein Sequence: MEPEQEPEPIGEDDPVDVPNSNPETYCRFCFSENEVEPLFAANGTQASAELLQRIQECIGIKLTRKEYCPSAICWSCTLTLEEFQCFRKRCLKFDTLVRRLLPTVKSEPSHRTATPTTAGQKEKKITSKQQPAANVADSEKNNGGPSTALKFKCQFCPRSFKHRMYLDQHLWKHRDRIAADAASAAGAGTKKIPHVNGNGSSAVKIKSEQAAQQKSAEQKAPPAAAAPAGGGATDRPISCEYCPRKFTRRMYYMQHLRRHKPDERLFRCRHCPRSFTSQLRRTGHERKIHAQLSNPKSEQKDTFSCPKCSRVFKHRSSLRMHMLNHDGQLPYGCDICNCRFYSVSYLALHKKRYHGPNAARSMTNGTSIPCHYCSRWFLRECDRSSHIKQMHADMHASKESAAGFNQLLEDCPPADSEGLTDPEMLPPNVHEPMMVIKEEEPDGHEAAASNSVANNPDTLQFYCYSCAMPFDTEDMFSEHLDDQHPFGGEQLMDQLQSASPFGEQQQQEQQDQDANVFKCPYCPKTFTRKWSLTQHLPTHIAKKGYQCEYCPAIFTRNEYLRTHRKRKHPNLPETGAHKCSYCPRMFNMVRYKKVHERIAHIKKGDILPEGDDTESSEVAAINSLQVEKQLDESSNSLAPELPSRASDSFDQASNDAPSVASVHNYADLEASSRLAVVLERLPAQELEQYRWQLEHYASLPPVIEIKRELLDPQYGDIEGEGFNDNAVYDDETNDSGKQLLKRKRTKFGITLHPCPHCSKLFKTRTALRLHALYHSGDLPHRCDECGVQFMRYNQLVYHTNRYHGANSATMAARYSCDYCPRIFLRKQDRTTHQLMVHARDQANAIDKSPALTIAKKTKRKDYVCRVCDAEFEKYRRCVRHITLIHAGSDGEPECRPIELCHCSICSGIYKKRDDWHEHLNDHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCSECGVMYDRYRDLLTHQSRYHPENQDDSVAREPLPKCNFCPRVFTRQRDVKYHQEQVHADQVIPAGDAEATNEPEEDEEPDEQQENEGDGLMTFGFGPEMFPEPDVQEDPVNMMID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095206;
90% Identity: iTF_00102538;
80% Identity: -