Aepi003156.1
Basic Information
- Insect
- Anopheles epiroticus
- Gene Symbol
- Rfx2
- Assembly
- GCA_000349105.1
- Location
- KB671954:103182-110467[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.2 7.1e+03 -2.9 0.1 14 31 6 23 3 29 0.78 2 2 8.3e-37 4.9e-33 113.0 0.0 3 78 193 268 191 269 0.97
Sequence Information
- Coding Sequence
- ATGCTAAATGTGCAGCTTTCATCACCTGAGAGCGTGCAGAACCATCACACCTACGTGCAGTATGTCGACTCGGACATGTACAACACTTCCGGCCAGGGACAGACGCAAATGACCTATCCGGTGTACACCGTTGGCGATTACGGTACAAATGGgcagcaacagcagcagcagcaacaacagTACTACACTACCGGTGGAAATTACGGCACCGCGGGTACCGGGGCCGGTAACACTCACGCCGACACTACTGGCAACAGTACCGCAAACGGCACCGGCACAACCGGAACCGGTTCCAATGGTGTTAACGCGAACGGACCCGTGTCGTCCGGCAATGGCGGTTCCGCTGGCAGCAACACTAATCAGCAACAGCAGCAGTACATTGTTCCGGTGGACGAGGCGGTCCTTCTCGGTACTGCCGGCAGCGGGAATACTTCCGGTGCGCAACAGCAGCAGTCCGACTCGTCGCCACAAAACATGACAGACGTAGCGTCCTACCTGCATGCGCACCAAGCGGCGTCCGCAGGTCAGGCGCTTGACTCCGCACCCAATCTAACCCACGCGGCTCGCGTTCTGCCCGCCACGGTGAGCTGGCTGATGGAGAACTACGAAACGGCGGACGGTGTGAGTTTGCCGCGGTCGACACTGTACAACCACTACATGTGGCACTGCAACGAGAACAAACTGGACGCGGTGAATGCGGCCAGCTTCGGCAAGCTGATCCGCTCGGTGTTTAGCGGGCTGCGGACGCGCCGGCTGGGGACGCGTGGCAACAGCAAGTACCATTACTACGGCATCCGCATCAAACCGACGTCTCCGCTGGTGCACGCGATCGAGTGTAAGCCACAGCACGGGTCGGGTGGCGTTGGTGGGGGACTGGGCGGGATGGTTGGACACCATCAGCAGCTCACTGGCAGCAACGGGCTGGGCGGAACGGGAGGTAACGGTGGTAGCAACGGGATGCACGGTCATGCAGGTGGTGGCGGTAACCATGCAAACGGGATGCATACTAGCAATGGCGGCTCGATGGGCCACGGCGCTGGTGGTGGTGGCCATCTCCAGCAAGGTGGTGGGGTGGGCGGAGGTGCAAACGGTGGAGGTAGTGGAGGTCACGGTATGTCATTGCATCATGGGCGAAGTAGCAAGAAGAACAGCTTCAAGGCTGAAATGCCCGAGTCCTGTGCGCAGTATCTCGGCGATCCAAACGGTGCCATACCGCAGTTCCCGATCATTGACATGATCCACCCGCTGCCAGACGATATCACGATGGAAGACGTGGACACGCTGCGCTCGATCTACCGCGAGCACTGCGAAGCATTCCTGGACGCCATTTTGAACCTGGACTTCAACATGATCGAGTCGCTGTGGCGCGAGTTTTGGCGCGCGGAAAACAACAACAACAATGGGGACGAGTGCGAGGAAGAGAAGTATCTGAGCAAGCAGAAGCTCTACCTGCTGACCCAGTGCGAACCAGTGCAGGAGTTTGTCAAGCACGTCGATCTGCAGTTTTACCAAAGCATGGTGGACGTGCTAATACCGGACGTGCTCCGACCGATACCGACCGGACTAACGCAGGCGATCAGGAACTTTGCGAAGAACCTTGAAAGCTGGCTCACGTCAGCGATGGGCGGTTGTCCGGAACCGATCGTCGCGATCAAGCTGTCGGCAGTGGCCGCTTTCGGGCAGACGTTACGCCGCTACACCTCGCTCAACCATCTGGCCCAGGCAGCACGGGCCGTCCTGCAGAACGGTACACAAATCGCACAGATGCTGAGTGACCTGAACCGGGTCGACTTTCGGAACGTTCAGGAGCAAGCGTCCTGGATCTGCCAGTGCGATACGGCGGTTGTGCAGCGGCTCGAGAACGACTTTAAGGCAGCGCTGCAGCAGCAGAACACGCTCGAGCAGTGGGCTGGCTGGTTGCAGAACGTTGTGGACGATGCGCTGCAGGAGTACCGTGGCAAGCCGAGCTTCGTGCACGCCGCGCGCCAGTTTCTGCTCAAGTGGAGCTTCTACAGCTCGATGGTGATCCGCGATCTGACACTCCGTTCGGCCGGCAGCTTCGGTAGCTTTCATCTGATACGCCTGCTGTACGACGAGTACATGTTTTTCATCATCGAGCATAAGGTGGCGAAGGCGACCAACACGACACCGATTGCGGTTATGGGTGAGAAAATCAACTCACGCCCCGTACAGGACGATCTGGACCGGATGCTCTACAGCAGCGAGTACGGCATGGTGAACGTGAAGCTAGAACCGAGCGCAAAACGTATGCGCAGTTAG
- Protein Sequence
- MLNVQLSSPESVQNHHTYVQYVDSDMYNTSGQGQTQMTYPVYTVGDYGTNGQQQQQQQQQYYTTGGNYGTAGTGAGNTHADTTGNSTANGTGTTGTGSNGVNANGPVSSGNGGSAGSNTNQQQQQYIVPVDEAVLLGTAGSGNTSGAQQQQSDSSPQNMTDVASYLHAHQAASAGQALDSAPNLTHAARVLPATVSWLMENYETADGVSLPRSTLYNHYMWHCNENKLDAVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPTSPLVHAIECKPQHGSGGVGGGLGGMVGHHQQLTGSNGLGGTGGNGGSNGMHGHAGGGGNHANGMHTSNGGSMGHGAGGGGHLQQGGGVGGGANGGGSGGHGMSLHHGRSSKKNSFKAEMPESCAQYLGDPNGAIPQFPIIDMIHPLPDDITMEDVDTLRSIYREHCEAFLDAILNLDFNMIESLWREFWRAENNNNNGDECEEEKYLSKQKLYLLTQCEPVQEFVKHVDLQFYQSMVDVLIPDVLRPIPTGLTQAIRNFAKNLESWLTSAMGGCPEPIVAIKLSAVAAFGQTLRRYTSLNHLAQAARAVLQNGTQIAQMLSDLNRVDFRNVQEQASWICQCDTAVVQRLENDFKAALQQQNTLEQWAGWLQNVVDDALQEYRGKPSFVHAARQFLLKWSFYSSMVIRDLTLRSAGSFGSFHLIRLLYDEYMFFIIEHKVAKATNTTPIAVMGEKINSRPVQDDLDRMLYSSEYGMVNVKLEPSAKRMRS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00100738;
- 90% Identity
- iTF_00102126; iTF_00095428; iTF_00094898;
- 80% Identity
- -