Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB672490.1:4626499-4631217[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.46 1.9e+03 -1.4 0.0 26 46 233 253 226 258 0.82

2 11 0.23 9.3e+02 -0.5 0.1 26 32 387 393 373 404 0.76

3 11 0.19 7.6e+02 -0.2 0.0 25 47 463 485 457 490 0.80

4 11 0.0035 14 5.4 0.0 21 45 487 511 482 514 0.89

5 11 0.00017 0.69 9.6 0.0 21 44 515 538 511 542 0.91

6 11 0.003 12 5.6 0.1 21 45 543 567 539 572 0.89

7 11 0.11 4.7e+02 0.5 0.1 21 46 595 620 582 623 0.82

8 11 2.4e-05 0.099 12.3 0.2 12 52 615 655 612 656 0.87

9 11 0.019 79 3.0 0.0 22 45 681 704 678 711 0.84

10 11 0.00099 4 7.1 0.1 21 48 708 735 703 739 0.86

11 11 0.0002 0.8 9.3 0.0 21 45 736 760 734 766 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.46	1.9e+03	-1.4	0.0	26	46	233	253	226	258	0.82
2	11	0.23	9.3e+02	-0.5	0.1	26	32	387	393	373	404	0.76
3	11	0.19	7.6e+02	-0.2	0.0	25	47	463	485	457	490	0.80
4	11	0.0035	14	5.4	0.0	21	45	487	511	482	514	0.89
5	11	0.00017	0.69	9.6	0.0	21	44	515	538	511	542	0.91
6	11	0.003	12	5.6	0.1	21	45	543	567	539	572	0.89
7	11	0.11	4.7e+02	0.5	0.1	21	46	595	620	582	623	0.82
8	11	2.4e-05	0.099	12.3	0.2	12	52	615	655	612	656	0.87
9	11	0.019	79	3.0	0.0	22	45	681	704	678	711	0.84
10	11	0.00099	4	7.1	0.1	21	48	708	735	703	739	0.86
11	11	0.0002	0.8	9.3	0.0	21	45	736	760	734	766	0.91

Sequence Information

Coding Sequence: ATGGTGAGCTGCTGGTCCACCGCGGCTAGGGAAGCACCCGTCATTGTGCAACGCGGAACCTGGCTTTTCTGCCGGAATTCATCGGTAGCGGAAGAAGCGCGTACGACAACTGTACGAGATCTCCCACTTCCCCTCATGCTTGGCAAGTATGGTGAGGCGGCCAGTTCCGGCTCGATGAAAAACCTGGAAAATGGCCTGCGGGACCGCGTGCTGTACCACCAGAACATGCTGAGCATGAACCTGACGGCCGAATTCTACCACAATCCATTCCTTTCGGCCAGTAccggtggtgttgttggtaaTAGCAGCGTCGGTACGACATCGGGCGCGACTGGCATGGCACAACAGTCGCAAAAGATCCCACACCATCCACAACAAACAGTAGCAGCGTCTACTTTGACCCAGTTTCAGTGTCAGCTCTGTCAGAAGTGCTTCATCTCGAACGTGCTCCTAGCGCAGCACATGAAAACGCACGAAAGCAACGGGTTCGTGACACGCGAAGGAACCAACTAcgtccaacagcagcagcagcaatctgTGCCGACTGCACCGTCCCCAGTTATCACCGTAGCAACATCCAACAGCAAAACTAGTCCTACCATACTTGCGCAGCACATCATCAAGACCGAGTACGTCGGTGGCTCGTCTTCCGGGCACTCGATGGGACAATTTTCCTATGGTTCGACGAAGCAGTTCGAGTGCCAGATCTGCCACAAGTCCTTTATGACCCAGGTGAACCTAAACCTGCACATGAAAATCCACGACATGACCGAGCTTAAGCCGGCTCCGATGTACTCACAAATAACGGGTTCGGGCACTTCCGGCTACCAAACACCCAGCACACATcacacccaacaacaacagcatgcGACGATGGTGGTTGGTACGCATGACGGTGTGTGCCAGATATGTCACAAAACGTTCAGTACGGCCGATCAATTTGCGGCACACATGAAAATCCAtgaaaatgagtttaaaaatCGTGCCCTTTACCACTCGGGCGGTGGTGCGAACGGTGCTGACGGGGGTTCGTCCACCCCACTTCCGCCCGGTAACGGTACGTCGGATCATTTCTACGCCGCGACTTTACATCCGACACAGCAACTTGCGCACGCATCACAACATCCACCGCCGCATCTCGACGCCAGCAAGGGCCACCGGTGTCCCATCTGCCACAAAATGTCCAACAACATCATCGAGCACATTAAACAGCACGAGGGCCAGCTAACGATGGGTGGTAGCGGCGGTGCGCCCGACGTAGCAGGTGGTTCGCCCCCGGGCTCGATCATCGTTTCGAGCGCGTCCGGCTATCAGCATCACCCGGCGGACGATTCACAGTCCTCGCTGGAGGAGGAAAGTGACGGTGGCGATAGTAGCGCCCGGAAGCACGAGTGCCTGATTTGCCATAAGAAGTTCTCCAGCTCGGGCAACCTGGCCATCCACATACGCGTGCACTCGGGCGAGAAGCCGTTCAAGTGCAGCGTGTGCGGCAAGGGGTTCATCCAGTCGAACAACCTGGCGACGCACATGAAGACGCACACCGGCGAAAAACCGTATGCGTGCACGATCTGCGGCAAAAACTTCAGCCAGTCGAACAACCTGAAAACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCGTGTACGATCTGCGGGAAGCGCTTCAACCAGAAGAACAATCTCACGACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGCGTGCAGTTCATGCACCCGTCCGATCTGGCGAACCACATGAAGTTCCACAACGACGAGAAGCCGTTCATCTGCTCCGTCTGCAACAAGGTGTATCTGAACCTGGACGAGCTGACCGAGCACATGAAGAAGACGCACCAGCAGGTCAAGCCGTACCGCTGCCACATCTGCGACAAGACGTTCACCCAGTCGAACAACCTCAAGACGCACATCAAAACGCACATCTTCCAGGACCCGTACAAGTGTCAGATGTGTTCGCGCTCGTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTGCACACGGCGGACAAGCCGTACGAGTGTACGTACTGCGGGAAGCGCTTCATCCAGTCGAACAACCTGAAGACGCACGtccgcacgcacacgggcgagaAGCCGTACCGCTGCACGATCTGCTCGAAGAACTTCAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACCGGCGAGAAACCGTTCGAGTGTACGATCTGCGACAAGCGGTTCAACCAGTCCAACAACCTgaacaaacacatcaaaacgCACGGCCAGGAGAAGGACCAACAGCACGCGAGTTGA
Protein Sequence: MVSCWSTAAREAPVIVQRGTWLFCRNSSVAEEARTTTVRDLPLPLMLGKYGEAASSGSMKNLENGLRDRVLYHQNMLSMNLTAEFYHNPFLSASTGGVVGNSSVGTTSGATGMAQQSQKIPHHPQQTVAASTLTQFQCQLCQKCFISNVLLAQHMKTHESNGFVTREGTNYVQQQQQQSVPTAPSPVITVATSNSKTSPTILAQHIIKTEYVGGSSSGHSMGQFSYGSTKQFECQICHKSFMTQVNLNLHMKIHDMTELKPAPMYSQITGSGTSGYQTPSTHHTQQQQHATMVVGTHDGVCQICHKTFSTADQFAAHMKIHENEFKNRALYHSGGGANGADGGSSTPLPPGNGTSDHFYAATLHPTQQLAHASQHPPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLTMGGSGGAPDVAGGSPPGSIIVSSASGYQHHPADDSQSSLEEESDGGDSSARKHECLICHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPFICSVCNKVYLNLDELTEHMKKTHQQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICSKNFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQHAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100669;
90% Identity: iTF_00099136;
80% Identity: iTF_00099136;