Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:12270-17808[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0012 0.069 12.9 2.6 2 23 142 164 141 164 0.91

2 16 0.00036 0.022 14.5 2.7 3 23 200 220 198 220 0.95

3 16 1.3e-06 7.6e-05 22.2 1.2 1 23 268 290 268 290 0.97

4 16 0.006 0.35 10.7 0.3 1 23 296 319 296 319 0.95

5 16 0.14 8.5 6.3 2.9 3 23 334 355 332 355 0.95

6 16 0.41 24 4.9 0.2 1 23 426 449 426 449 0.92

7 16 0.00022 0.013 15.2 0.6 3 23 480 501 478 501 0.94

8 16 1.5 88 3.1 4.6 1 23 512 535 512 535 0.96

9 16 5.9e-05 0.0035 17.0 2.9 1 23 654 676 654 676 0.96

10 16 0.13 8 6.4 0.7 1 23 682 705 682 705 0.84

11 16 0.014 0.82 9.5 0.2 2 23 717 739 716 739 0.94

12 16 5.2 3.1e+02 1.4 1.3 3 23 768 789 766 789 0.94

13 16 0.078 4.6 7.2 0.9 2 23 809 830 808 830 0.94

14 16 3.7e-06 0.00022 20.7 4.8 1 23 854 876 854 876 0.98

15 16 0.0066 0.39 10.5 0.4 1 23 882 905 882 905 0.93

16 16 0.00051 0.031 14.0 1.3 2 23 919 941 918 941 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0012	0.069	12.9	2.6	2	23	142	164	141	164	0.91
2	16	0.00036	0.022	14.5	2.7	3	23	200	220	198	220	0.95
3	16	1.3e-06	7.6e-05	22.2	1.2	1	23	268	290	268	290	0.97
4	16	0.006	0.35	10.7	0.3	1	23	296	319	296	319	0.95
5	16	0.14	8.5	6.3	2.9	3	23	334	355	332	355	0.95
6	16	0.41	24	4.9	0.2	1	23	426	449	426	449	0.92
7	16	0.00022	0.013	15.2	0.6	3	23	480	501	478	501	0.94
8	16	1.5	88	3.1	4.6	1	23	512	535	512	535	0.96
9	16	5.9e-05	0.0035	17.0	2.9	1	23	654	676	654	676	0.96
10	16	0.13	8	6.4	0.7	1	23	682	705	682	705	0.84
11	16	0.014	0.82	9.5	0.2	2	23	717	739	716	739	0.94
12	16	5.2	3.1e+02	1.4	1.3	3	23	768	789	766	789	0.94
13	16	0.078	4.6	7.2	0.9	2	23	809	830	808	830	0.94
14	16	3.7e-06	0.00022	20.7	4.8	1	23	854	876	854	876	0.98
15	16	0.0066	0.39	10.5	0.4	1	23	882	905	882	905	0.93
16	16	0.00051	0.031	14.0	1.3	2	23	919	941	918	941	0.96

Sequence Information

Coding Sequence: ATGCCTAAGGACATGGAAGGAGCCGCTTGTGAAAGTGCGATGGATCCCGAGGAGGAACCGGTTGTGGACGACAATCCAACAGCGGTACCGAACCAGTACCCGGAATCCTACTGCCGTTTCTGCTTTTCCGAAATCGACGTTCAGCCTCTGTTTTCGTCAGAATGTAATCCAAAATCGAATGTGATACGCCGCCTATTCGAGTGCATCGGATTGCGCCTGACGAAGGATGTCGATTATCCAAGCAGCATATGCTTGATGTGTTCCCTGACGATGCAAGAGTTCCAGTGCTTTCGGGATCGTTGCTTGAAATACGATGAAATTTTCCGCCGTTGCCGACAGCTGAGCGAAAAGAAACAACGGGATGTGATCGATCATCGTCAGAAAGCAGCAGCTTCCTTGCCTTTGGATGCTAAGCCAAGCTTATGCTGTCAATATTGCCAGCAGCAATTCTCAAACAAAGTTGATCTCAACCAGCACTTGGATCAAACTCACGGAGATCGGAACAGGCAACCTCCCCTGAATGGAGGCTCTACGGCACCGGAAGTACCGGCAGTGAACGGAACCCAAGGACCAATGCCCAAACCGCGGAACATCTGTTGTGCATACTGTCCGCGAAAATTCACTCGTCAAATGTATTACGAGCAGCATCTGCAGAAGCACACCAAACTGAAAGTGCAGCGAGAACGACCGTTCCGGTGTTCGTGCTGTCCACGTTCCTTCGAGTCGTTGCCGCGGCTAAAGTTCCACGAAAAGAAAGAGCACGGCAAAAAGACTAGCAAGAAAACGAACGAAGGAACATCATTCGTTTGCCCGGAATGTTCAAAATCCTTCAAATATCGTTATTCACTGCGAATGCATATCCTCAACCACCGTGGCCAGTTGCCGTTTGTGTGTGAAATATGTGACAGTGGTTTCTACAACGTGAACTATCTGACCGCACACAAGGCTCGTTATCATGGTCCGAATGCTGTGGCCGTTGTGCGCGGTGAAAAAATCGCCTGTCGATATTGTCCTCGCACTTTTCTGCGGAAGTGTGACCAGACGAGTCACATGAAGCAAATGCACCCAAACATTCCACTAGAGGATCAGCCCGAGGAAAGTCATGCGCCGGAAATGCTCGCAGAGTGTCCACCGGCAGACAGTGATGGATTGACCGACCCGGAACTTTTACCTCCTAACGTCCATGAGCCGGTGATGGTGATAAAGGAAGAGCAACTGGAAAAGGTGGTCGAAAATCCAGTTCCGGTTATGAAGACTGAAGCCAAGGGTGCAAATTTCTATTGTGTAACCTGTGCGATGGAGTTCGATACGGAGGACATGTACTCGGAACACATGGACGATCAGCATTCACTCGGAGGGGCCGAATCTGCTGATCAGACTGAAGAACATCGTAGCCAAGATGGGGTAAGGTTCCGTAAAAGAAAGAGAATTATCTGCTGCCAGTATTGTCCGGCCATTTTTAGTCGGCCCGGCTATTTAAACGCACATACGTTGCGCAAGCATCCCGACAAATATGAAACTTCCATGGGTTCGTACAAGTGTCGCTTCTGTCCACGACAGTTCCATGAGCTACGATATCGAAAGGTACACGAGCGAATGACGCACGCAAGACGAGGTGAAATATTGCCGGAGATGCACGAATTTTCCAGCGAAACAACGCACAGTGTCAGCACGATGGGACTGGAAGCGTCGTCGGAACCCTCGAATGATGGAACGAGTACAATGAGCGATCTTTCTCTTCTGGGAGGCTCATCATTGGTGATCCTATTGGAACCTCTACCACCGAAGGTGCTGGCCACTTACCAATGGCAGCTGGACGAATATGATAGGAGACAGGAAGAACGGGATGTCAAGCCCCTGAACATCGCAGCAATCGATGGAACGTGTAGTTCGCCTGCCGGCAGTAGTGAGACCAGCGATAGGGTCGATTCAATGCGAACCAAGCTTGGCATCAAGTTGCATCCTTGCGGGAAATGTGAGAAAATGTTTAAAACTCGCCAGGCACTTCAGAAGCACACGATGTATCATATCGGCCAACTTCCATATCGATGTGACGAGTGTGGCGTACAATTTATGCGGATAGGACAGCTTTCCTTTCACAAATCGCGCTATCATGGTGATAGCGCGCCTACCGTTGTGAACCGCGTTAGCTGTGACTACTGTCCACGAATATTTCTACGCAAGCAGGATCTGGCCAGCCATTACTTTATGGTTCATGGTAAAGATCGTGCTGAGCAGCCCTACAGAACGGATGATCCTTCGCCGGAGCAGCGTAAAAAATCGAAACGAAAGGAGTACTGGTGTCAAGGGTGCGGCAGTTTGTTCGATCGCTATCGTAAGTGTGAGCGACACATCGCGAAGGAACACGGTATGGATGCGGCGGACGGTGATGCTGGAGCGACGATAAAACCAATCAAGCTTTGCCGCTGCAGCGTTTGTGCGACGATCTTCAAAAAACGTGACGAATGGCTTGATCATCTGTCCGGTCACGCGAATGTCCGGCCGCACAACTGCGAGCAGTGCCTGAAAGGACGTAAGAAGTTTGGTCGCAAACAGGTACACAAGTGCACCTACTGTCCGAAGGTCTTCATTCACAGTACAACACTAAAGTCGCATCTTCGAATCCACACCCAACAGCTCCGCTTCCCATGCAACGAGTGTGGCGTCATGTACGATCGGTACCGCTACTTGGCCATGCATAAAGTTCGCTACCATTCAGAGGATGCATCGGCCGCCACGCAGTCACAGCTTATCAAGTGTGGATTCTGTCCTCGTATGTTCACTCGGCTGCGGGACGTTAATCACCACCAGATGTCGGTACACTCCGATGGGATTATCATGGACACGGCCGAGCAGCCCGACGGAATGGAGCAAGAACAGCCTGCGCAACAACTGCTGCCCCACGAATTCGGCAGTCTTTCAGAACTATTGCTTAGTAGCAATTGTAACGATCTTACAAACGGTGCCACCATCAAGCAGGAATTTCCATCCAGTTTGGAACAGTGA
Protein Sequence: MPKDMEGAACESAMDPEEEPVVDDNPTAVPNQYPESYCRFCFSEIDVQPLFSSECNPKSNVIRRLFECIGLRLTKDVDYPSSICLMCSLTMQEFQCFRDRCLKYDEIFRRCRQLSEKKQRDVIDHRQKAAASLPLDAKPSLCCQYCQQQFSNKVDLNQHLDQTHGDRNRQPPLNGGSTAPEVPAVNGTQGPMPKPRNICCAYCPRKFTRQMYYEQHLQKHTKLKVQRERPFRCSCCPRSFESLPRLKFHEKKEHGKKTSKKTNEGTSFVCPECSKSFKYRYSLRMHILNHRGQLPFVCEICDSGFYNVNYLTAHKARYHGPNAVAVVRGEKIACRYCPRTFLRKCDQTSHMKQMHPNIPLEDQPEESHAPEMLAECPPADSDGLTDPELLPPNVHEPVMVIKEEQLEKVVENPVPVMKTEAKGANFYCVTCAMEFDTEDMYSEHMDDQHSLGGAESADQTEEHRSQDGVRFRKRKRIICCQYCPAIFSRPGYLNAHTLRKHPDKYETSMGSYKCRFCPRQFHELRYRKVHERMTHARRGEILPEMHEFSSETTHSVSTMGLEASSEPSNDGTSTMSDLSLLGGSSLVILLEPLPPKVLATYQWQLDEYDRRQEERDVKPLNIAAIDGTCSSPAGSSETSDRVDSMRTKLGIKLHPCGKCEKMFKTRQALQKHTMYHIGQLPYRCDECGVQFMRIGQLSFHKSRYHGDSAPTVVNRVSCDYCPRIFLRKQDLASHYFMVHGKDRAEQPYRTDDPSPEQRKKSKRKEYWCQGCGSLFDRYRKCERHIAKEHGMDAADGDAGATIKPIKLCRCSVCATIFKKRDEWLDHLSGHANVRPHNCEQCLKGRKKFGRKQVHKCTYCPKVFIHSTTLKSHLRIHTQQLRFPCNECGVMYDRYRYLAMHKVRYHSEDASAATQSQLIKCGFCPRMFTRLRDVNHHQMSVHSDGIIMDTAEQPDGMEQEQPAQQLLPHEFGSLSELLLSSNCNDLTNGATIKQEFPSSLEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092349; iTF_00093028;
90% Identity: -
80% Identity: -