Aaqu003686.1
Basic Information
- Insect
- Anopheles aquasalis
- Gene Symbol
- -
- Assembly
- GCA_002846955.1
- Location
- NJHH01007555.1:10266-13257[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00039 0.024 14.6 2.7 3 23 156 176 154 176 0.95 2 14 1.4e-06 8.5e-05 22.3 1.2 1 23 224 246 224 246 0.97 3 14 0.0063 0.4 10.8 0.3 1 23 252 275 252 275 0.95 4 14 0.16 9.9 6.4 4.1 2 23 289 311 288 311 0.95 5 14 0.43 27 5.0 0.2 1 23 386 409 386 409 0.92 6 14 0.00023 0.015 15.3 0.6 3 23 442 463 440 463 0.94 7 14 1.6 99 3.2 4.6 1 23 474 497 474 497 0.96 8 14 7.2e-06 0.00045 20.0 2.6 1 23 620 642 620 642 0.97 9 14 0.14 9 6.5 0.7 1 23 648 671 648 671 0.84 10 14 0.015 0.92 9.6 0.2 2 23 683 705 682 705 0.94 11 14 5.5 3.5e+02 1.5 1.3 3 23 735 756 733 756 0.94 12 14 0.083 5.2 7.2 0.9 2 23 777 798 776 798 0.94 13 14 0.007 0.44 10.6 0.4 1 23 823 846 823 846 0.93 14 14 0.00083 0.052 13.5 1.5 2 23 860 882 859 882 0.96
Sequence Information
- Coding Sequence
- ATGCCTGCGGACATGGAAGGGGCCGCTAGTGAGAGTGTGATGAAtctcgaggaggaggaaccggtTGTCGACGATAATCCAACAGCGGTGCCGAACGCGTACCCGGAAACCTACtgccgcttctgcttctcggAAATCGACGTCCAGCCTCTGTTTTCCCCAGAATGTAATCCCAAATCGAGTGTGCTATTGCGAGTGCGCCTGTTCGAGTGCATAGGACTGCGACTAACGAAGGATGTCGATTATCCCAGCTCCATATGCTTAATGTGTTCCTTGACGCTGCAAGAGTTCAAATGCTTTCGGGATCGTTGCTTGAAGTATGATGAAATCTTCCGCCGTTGCCGAAAGCAGAGCGCAGAAAAGCGGCATCCGGATGTGGTTGATCCACGCCAGAACGCGACAGAGGTGGTACGGAAAGTGAACGGAACAAAAGAACCCGTGCCCAAACCGCCGCGCAACATCTGTTGTGCATACTGTCCACGGAAATTCACGCGGCAAATGTACTACGAGCAGCATTTACAGAAGCACACCAAACTGAAGGGGCAGCGAGAACGCCCGTTTCGGTGTTCGTGCTGTCCACGTTCCTTCGAGTCGCTGCCCCGGCTAAAGTTCCACGAAAAGAAAGAGCACGGCAAAAAGGCTAGCAAGAAAGCGGGCGAAGGGACATCATTCGTTTGTCCGGAATGTTCGAAATCCTTCAAATATCGTTATTCGCTGCGGATGCACATCCTCAACCATCGTGGCCAGTTGCCGTTCGTTTGTGAAATATGTGACAGTGGGTTCTACAACGTCAACTATCTGACCGCACACAAGGCACGGTACCATGGTCCGAATGCTGTGGCCGTAGTGCGCGGTGAAAAGATCACCTGTCGATACTGTCCGCGCAGTTTCCTACGGAAGTGTGATCGGACGAGTCACATGAAGCAGATGCACCCGAACATTCCCGAGGAAAACCATGCACCGGAAATGCTCGAAGAGTGTCCCCCGGCAGACAGCGAAGGAATGACCGATCCGGAGCTCCTACCACCGAACGTCCACgagccggtgatggtgataaagGAGGAGCAGATGGAGCAGGAGTCGGAAGATCcggttgttccggttgttccggATGTTCCGGTTGAAACGAAGACTGAAGCCAAGGATGCAAAGGATTTCTATTGTGTAACCTGTGCGATGGAGTTCGATACGGAGGACATGTACTCGGAGCACATGGACGATCAGCATTCCCTCGGAGGGGCCGAGTCTACTGATCAGACTGAAGGGGGGCACCGTAGCCAAGACGGGGTGGTACGGTTCCGTAGCCGAAAGAGAATCATCTGCTGTCAGTATTGTCCCGCAATATTTAGCCGGCCCGGTTACTTGAACGCACATACGTTGCGGAAGCACCCGGACAAGTATGAAACTTCCATGGGTTCGTACAAGTGTCGCTTCTGCCCACGACAGTTCCATGAGCTACGATATCGAAAGGTCCACGAGCGAATGACGCACGCCAGACGGGGTGAGGTATTGCCGGAGATGCACGaattttccagcgaaacaaCACACAGTGTGGTGGTCAGCACCGCGGGCCTAGAAGCGACGTCCGATGAACCTTCGAACGATGGAACGAGTACAGTGAGCGATCTTTCTCTTCTGGGCAACGCATCACTGGTGATCCTGTTGGAACCGCTACCACCGAAGGTGCTGGCCACTTACCAGTGGCAACTGGACGAGTACGATAGGCGAGAGGAAGAACGGGATGTCAAGCCACTGATCACTGCAGCACTCGATGGAGGAACGTGTAGCTCTCCTGCCGGCAGTAGTGAGACCAGCGAACGGGTCGATTCAATGCGCACCAAGCTGGGCATCAAGTTGCACCCGTGCGGAAAATGtgagaaaatgtttaaaactcGCCAGGCACTTCAGAAACACATGATGTACCACATCGGCCAGCTGCCGTACCGGTGTGACGAGTGTGGTGTGCAGTTTATGCGGATAGGACAGCTTTCCTTTCACAAATCGCGCTATCACGGTGATAGTGCGCCGACCATTGTGAACCGGGTTAGCTGTGATTACTGTCCGCGAATATTTCTACGCAAGCAGGATCTGGCCAGCCATTACTTTATGGTCCATGGTAAAGATCGTGCTGAGCAACCGTACCGGACGGATGATGATCCTTCGCCGGAGCAGCgtaaaaaatcgaaacgaaaggagTACTGGTGCCAAGGGTGCGGCAGTTTGTTCGATCGTTATCGTAAGTGTGAGCGACACATCGCGAAGGAACACGGTATGGACGCGGCGGCGGACGGAGACGCGGGAGCGACGATCAAGCCAATCAAGCTTTGCCGCTGCAGCGTTTGTGCGACGATCTTCAAGAAGCGCGACGAATGGCTTGACCATCTGTCGGGTCACGCGAACGTCCGGCCACATAACTGCGAGCAGTGCTTGAAAGGACGCAAGAAGTTTGGCCGCAAACAGCTCCGCTTCCCGTGCAACGAGTGTGGCGTCATGTACGATCGGTACCGCTACTTGGCCATGCATAAAGTGCGCTACCATTCCGAGGACTCATCGGCCGCCGCCCAGTCACAGCTGCTCAAGTGTGCATTCTGTCCCCGTATGTTCACCCGACTGCGGGACGTTAATCACCATCAGATGTCGGTGCATTCCGATGGGATTACGGTGGACACGGCCGAGCAACCTGACGGAGTGGACCAAGAACTACGGCCTACATCACAGCTACTGCCGCACGAGTTCGGCAGTCTTTCTGAACTGCTGCTTAGTAGCAACTGTAACGATCTTTCAAACGGAGCCCCTAACATCAAGCAGGAGCTTCCTTCCAGTTTGGAGCAGTGA
- Protein Sequence
- MPADMEGAASESVMNLEEEEPVVDDNPTAVPNAYPETYCRFCFSEIDVQPLFSPECNPKSSVLLRVRLFECIGLRLTKDVDYPSSICLMCSLTLQEFKCFRDRCLKYDEIFRRCRKQSAEKRHPDVVDPRQNATEVVRKVNGTKEPVPKPPRNICCAYCPRKFTRQMYYEQHLQKHTKLKGQRERPFRCSCCPRSFESLPRLKFHEKKEHGKKASKKAGEGTSFVCPECSKSFKYRYSLRMHILNHRGQLPFVCEICDSGFYNVNYLTAHKARYHGPNAVAVVRGEKITCRYCPRSFLRKCDRTSHMKQMHPNIPEENHAPEMLEECPPADSEGMTDPELLPPNVHEPVMVIKEEQMEQESEDPVVPVVPDVPVETKTEAKDAKDFYCVTCAMEFDTEDMYSEHMDDQHSLGGAESTDQTEGGHRSQDGVVRFRSRKRIICCQYCPAIFSRPGYLNAHTLRKHPDKYETSMGSYKCRFCPRQFHELRYRKVHERMTHARRGEVLPEMHEFSSETTHSVVVSTAGLEATSDEPSNDGTSTVSDLSLLGNASLVILLEPLPPKVLATYQWQLDEYDRREEERDVKPLITAALDGGTCSSPAGSSETSERVDSMRTKLGIKLHPCGKCEKMFKTRQALQKHMMYHIGQLPYRCDECGVQFMRIGQLSFHKSRYHGDSAPTIVNRVSCDYCPRIFLRKQDLASHYFMVHGKDRAEQPYRTDDDPSPEQRKKSKRKEYWCQGCGSLFDRYRKCERHIAKEHGMDAAADGDAGATIKPIKLCRCSVCATIFKKRDEWLDHLSGHANVRPHNCEQCLKGRKKFGRKQLRFPCNECGVMYDRYRYLAMHKVRYHSEDSSAAAQSQLLKCAFCPRMFTRLRDVNHHQMSVHSDGITVDTAEQPDGVDQELRPTSQLLPHEFGSLSELLLSSNCNDLSNGAPNIKQELPSSLEQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00098562;
- 90% Identity
- -
- 80% Identity
- -