Adar000177.1
Basic Information
- Insect
- Anopheles darlingi
- Gene Symbol
- -
- Assembly
- GCA_000211455.3
- Location
- scaffold:42402-71710[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00048 0.028 14.1 4.0 1 23 247 269 247 269 0.97 2 11 0.0053 0.32 10.8 9.0 1 23 277 299 277 299 0.96 3 11 8.8e-05 0.0052 16.4 6.5 1 23 305 327 305 327 0.98 4 11 0.00027 0.016 14.9 2.3 1 23 333 355 333 355 0.95 5 11 4e-06 0.00024 20.7 0.7 1 23 361 383 361 383 0.97 6 11 5.7e-05 0.0034 17.0 0.1 1 23 389 411 389 411 0.96 7 11 4.4e-05 0.0026 17.4 1.3 1 23 416 438 416 438 0.97 8 11 0.0017 0.099 12.4 0.6 6 23 449 467 444 467 0.89 9 11 0.00025 0.015 15.0 0.1 1 23 551 573 551 573 0.97 10 11 0.022 1.3 8.9 6.7 1 23 713 735 713 735 0.97 11 11 0.0038 0.23 11.3 4.9 5 23 748 766 740 766 0.92
Sequence Information
- Coding Sequence
- ATGTGTGCGGCACAGACGAACCCGCCGTCCAACTTTAACTATACCTGGGGCTACGGCGAGAATACGCGGGGCGAATCCGTGGTCGAGATAGCGCCCAACATCACCTACAATGTGGCAGCGGACGCATCAACGATGCCATACTTGCAGCTACCGGACGGTGCTAGCATAATAGTGCAGAAGGATGGCAAGGGAGCGATCACACACGGTAACAAAGCCGTCCGGCGGATGATCGTCGTGAACGATCCATCTACACTGCAGCAAACAGGAACACAGAGAATTATCACAACCAGTGGTACAGCGGCAACCGTCACAACGGGACATCAAAAGAAGCATGAAGTCATAACAAACGGAATCATCGAGACAAAGCCGAAAACGGCCATCCTGACGACGGGTGCCGGTGGTGCATTCATGTCCCCTATCGGACCGATACAGCTGACAGCTGAGGAATGCAACGATATCTTGATGAAGCGTGCGGCTGCTGCCGTCGCCGCCAACAACCAGCAGGCCATCACCAACAACACCGATGGTCATCATGCATCCATCTCGGTGCAGGTGCAGAAGGTGATCCAGGGACTTGAGGAAGGGGACGATTCACAGGCGACCGCCACGACCCATCAGCTCAAGATTGAGCCATCGTTGAGCATTTCTCCGAAGCTGGAAGCGGTGGAGATTGATTACAATGATTACGTACAGGAAGATCCCACACCTACACCGAATGTGGTACCAAAGGAGCGTCCTTATTCGTGCGATCAGTGTGGTAAATCCTTCTTGTTGAAGCACCACCTCACAACACACGCACGCGTCCACACAGGTCCGGGCGAACGTCCGCATGTGTGCGTGCACTGTGGCAAGGACTTTGCTCACAAGCACTGTCTGAACACGCATCTGCTTCTGCACTCGACCGAACGGCCGTATCAGTGTCAGGAGTGCAAGAAGAGTTTCACGTTGAAGCACCATCTGCTGACACATTCGCGAGTTCACTCGCGCGATCGGCCCTTTGTGTGCCAGGAGTGTGGTCGCTCGTTCCCGTTGAAGCGCCACCTGGTGACACACAGCAAGTTCCATGCCGGTGAGCGGCCGTACGTGTGCGAAGATTGCGGTGAAAGTTTCGCCCAAAAGGAGCATCTTGTGATGCACTCGCGGTTCCACGGTTCCGTCAATCCGTTCGTCTGCGCTGACTGTGGCGCTACCTTCCCGCGTAAGTTCCAGCTGGTGAACCATGGTAAACTGCACGGTCGCATACCGCACTCGTGTACGCTGTGCGGTAAAGAGTTCCTTCAGAAGCGCACCCTTGCGGCCCATATGAGGATCCATACGGGCGATCAGCCTTTCCCATGTATCGCCTGCGGTGAAGGATTCCGTACCAAGTCGGAACTGAACGCGCACAATCGGCACACTCATGGTGGCGTTAATCCGAACTCATCGAACACGACCATCATCACGACCAACACGGTCGTCACATCGAATGCCcaacagcaacagcagcaagcgcaggcacaggcccagcagcagcaacagcacattgaagttcagcagctgcagcaccaccagggccaacagcaacagGTGCAGGATGTGTCGAATGGGAACATTATCACGACGATCGCAACCACCGGTCAAGGTTCGCCCGATACGTCACCACGGCCACAGTATGCTTGCCGGGAGTGTGGCAGTGCCTTCAACAGTCGCGAAGCGTTGGCCCTCCATCTGCGTCTGCACACCGGTGACAAGAGCCTGATGACGGATCTGTGCGCCCTGACAGCCGCCCTTCCTGGTCATCTATTCCCAGCTGTCAACCAAGAATATTCGATCACTCCTAATGGTGGCACGATCATGACGACCAACTCTGTAATGCAAAACTCCACCATTCCAGTACAAATTATCACCTCCTCGGGGCAAGTGGTACCGCAGATTcaaccacaaagtccaccgcagcagcaacagcaacagcaacagcaccaccaacagcagttgcaacatcagacacaagtggtgcagcaacatcaaacgcatacggtcgtacaacaacagaaccaacagcagcagcaacagctacagcagcaacagcaacaacagcaacaacaacagcaacagcagcagcaatccgtcgttgtatcacaatcgaaaccaaaagcacacgtctgcaccagctgcagcaAAGGATTTGCTACCAAGCATGGTCTGTGTCTGCACAATAGGCGCCATCCCAACGGTGGTTGTACGGTTCGAACGCACGTGTGTGAGTGTGGTAAGGCGTTCTTCCAGAAAAATCATCTAATGTTGCACCAGCGTCAACATCTGGAGCAGAATCAACGTGGTGCTGCTACCGGTGGTAATGCCACTGCCGGTGGTCAACAGACGCAGCAGCAACAGCAACAAGTGCAGGCTGCTGGCGGCCAACAGCAACAGCTGGTTGTGATTCAACAATCAAACCAGGAAGCACTGGTTcagcagcaacaacagcagcagcaggcagctcaacagcaacagcagcaagcggcacaacagcagcaccagcttcaacagcagcaacagcaagtcgtacagcaacagcagaatcagcagaacaatcagcagcaCGGCATGCGCAACCTGGTGATTGCGAATCAGCCCGTCCAGCTACAGGTGATGCAGGAAGGTAACGCAGCCCAAGTGATCAAGTACGAGATCATCCACGACACCTCTCGTCAGTCGAATGTCGAGTGA
- Protein Sequence
- MCAAQTNPPSNFNYTWGYGENTRGESVVEIAPNITYNVAADASTMPYLQLPDGASIIVQKDGKGAITHGNKAVRRMIVVNDPSTLQQTGTQRIITTSGTAATVTTGHQKKHEVITNGIIETKPKTAILTTGAGGAFMSPIGPIQLTAEECNDILMKRAAAAVAANNQQAITNNTDGHHASISVQVQKVIQGLEEGDDSQATATTHQLKIEPSLSISPKLEAVEIDYNDYVQEDPTPTPNVVPKERPYSCDQCGKSFLLKHHLTTHARVHTGPGERPHVCVHCGKDFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRDRPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEDCGESFAQKEHLVMHSRFHGSVNPFVCADCGATFPRKFQLVNHGKLHGRIPHSCTLCGKEFLQKRTLAAHMRIHTGDQPFPCIACGEGFRTKSELNAHNRHTHGGVNPNSSNTTIITTNTVVTSNAQQQQQQAQAQAQQQQQHIEVQQLQHHQGQQQQVQDVSNGNIITTIATTGQGSPDTSPRPQYACRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHLFPAVNQEYSITPNGGTIMTTNSVMQNSTIPVQIITSSGQVVPQIQPQSPPQQQQQQQQHHQQQLQHQTQVVQQHQTHTVVQQQNQQQQQQLQQQQQQQQQQQQQQQQSVVVSQSKPKAHVCTSCSKGFATKHGLCLHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLEQNQRGAATGGNATAGGQQTQQQQQQVQAAGGQQQQLVVIQQSNQEALVQQQQQQQQAAQQQQQQAAQQQHQLQQQQQQVVQQQQNQQNNQQHGMRNLVIANQPVQLQVMQEGNAAQVIKYEIIHDTSRQSNVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00097245;
- 90% Identity
- iTF_00092325;
- 80% Identity
- -