Adar003177.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
-
Assembly
GCA_000211455.3
Location
scaffold:59586-63100[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8.2e-05 0.0049 16.5 0.5 1 23 246 268 246 268 0.99
2 15 1e-05 0.00061 19.4 4.2 1 23 346 368 346 368 0.97
3 15 8.5e-06 0.0005 19.6 2.3 2 23 434 455 434 455 0.97
4 15 0.35 21 5.1 1.4 1 16 523 535 523 542 0.72
5 15 3.8e-07 2.3e-05 23.9 2.4 1 23 603 625 603 625 0.97
6 15 4.5e-08 2.7e-06 26.8 0.6 1 23 631 653 631 653 0.99
7 15 3.4e-09 2e-07 30.3 2.2 1 23 659 681 659 681 0.99
8 15 5.7e-09 3.4e-07 29.6 1.8 1 23 687 709 687 709 0.98
9 15 0.00023 0.014 15.1 0.2 2 23 712 733 711 733 0.95
10 15 0.00022 0.013 15.2 0.4 1 23 739 762 739 762 0.97
11 15 1.9e-08 1.1e-06 28.0 4.7 1 23 768 790 768 790 0.99
12 15 0.00015 0.0087 15.7 0.8 1 23 796 818 796 818 0.98
13 15 2.6e-08 1.5e-06 27.6 1.8 1 23 824 846 824 846 0.99
14 15 1.6e-06 9.7e-05 21.9 1.6 1 23 852 874 852 874 0.98
15 15 2.3e-08 1.4e-06 27.7 2.0 1 23 880 902 880 902 0.98

Sequence Information

Coding Sequence
ATGAGGCTGAATATTGACGACGTGTATGGGCCGCTTAAGAAGAGGGGAAGCGGGGTAAACGTCAACTTGACTTTTGCTACTGCCACCCGTACGAAAAGAAGAAGAAGCAGGAAAATATTTTCTCGGACGGTTTTGGTGCGTGCTGGCGAAAGAATTTTCATCTTTGGTGGTTTTTCGGCGGAACGGAGCAGATTTTCCGTTTACTGTTCCTCGGAGGGCCTCGATCCGCTGTTCGATAGCATCCGAGTCGAGGTGTTCGGGGCGGAAGCTGCCCGCGATGTTGGCATTGTGCAACGTCGAACTGGCGAACGAGGCAGCGTAATACAAGAAGACAAGCGCAAGGTAATGCTCGGCAAGTATGGCGATGCGAGCTCCAGCTCGATGATGAACCTTGAAAGCGGTCTTCGTAACCGAGTACTCTACCATCAGAACATGATGGGCATGAATCTGATGGCCGAATTCTATCAccacaacccaacactagtgaacgcagccacagtcagcagttccgttaccggcagcagcagcagcagcagcaataatagcgcgatcgcgcagtcacaaaaaatgctcaacagcttaagtggaaccatagcaaacgctggtggaaaccatcagcaaccgtcgcagcatACTAACGGCACACCGCTCGCCATTTCGACCGTTTCAACAGCGGCCACCGTCACAAGTACATCGTCGTCATCGTCCTCGTCGTCGCAGCAGCCATTAGCACAGTTTCAGTGTCAAGTTTGTCAGAAAACGTACCTCACCAGCGCGATGCTTGCGGTACACATGAAAACGCACGATAATGCAGCCGGAGGATTCGTGAGCCGACAGGAGGCCACCGTTGGCAGCAGCTATCTTCAGCCGTCTTCTTCATCGCTCGAACACGTATCCGCACCAGCTGTAGCACATGGAGCGAGCAGTAAAACTAGTCCCCCGCTGCTGCTAGCTCAGCACAGCATCAAGAGTGAGTACGCAGGTACCGCACGCGGTATCGGTCAGTTCTCCTCACCGTACGGTATTATCAAGCAGTTTGACTGCCACATCTGCCATAAATCGTTCATGACACTAATGAACCTGAATCTTCACATGAAGATCCATGAAAACGACCAGAAGGTGGTTGCCGCAGCAACTGCCGCCGCAAACGTGTATTCGTCGCACGCTGGAGGCACCGGCACgacctatcaccatcagctgacccatcaacagcagctCCATCCTACGCTGCTGCAGGCGGCATCGTCGTCTGGGGCTGTACCCTCAGCTACTGCAACGACAGGGCGTAACGCCGATGGTGTTTGCCAGATTTGTCACAAAACATTCAACAGCACGGAACAGTTTACGGCCCACATGAAGATCCACGAGGAGGAATTTAAGAATCGTGCCCTCTATCACTCCTCCGCTGCTACCGGCAGCAGTACCGCAGTGGCCACAAGTGCTGCGGCTCAAACGATTAACCCGTTCTATCCTACTCTGCCACAAACACTCGCTCCAGCGGCATCCACACAGCCACAGCAGCAGCAACAACTCCCAGCGGTACATTTGTATGAAAGCTCCAAGGGACACCGATGCCCGATCTGCCACAAAATGTCCAGCAACATTATCGAGCACATAAAACAGCACGAAGGACAGCTAATCATGGGAGGAGGTGGATCATCAGCGACGGCACCCGGTGGTGGTAGTCCATCGGTGGATCGGGCCTGCGCAACGCCAGGTTACCAGCTGAACGAAGAAACATCGCAAGCATCCTCGCTGGCGGAGGTCAGCGATAATGAGGCtggcgatgatgatcagcgcaagcagcacgagtgcttgatctgtcacaaaaagttctcgagctcaagcaatctggccatccacatccgggtgcactccggggagaaaccgttcaagtgtagtgtctgcggcaaaggcttcatccagtcgaacaatctggccacacacatgaaaacgcataccggcgaaaagccttacacgtgtacgatctgtggcaagaagtttagccagtcgaacaacctgaagacacacatccggacacacacgggcgagcggccttacgcgtgtacgatttgtggtaagcggttcaaccagaagaacaacctgacgacgcacatgcgcactcaccagctggtgtgcatggtgtgcggggtccagtttgcgcatccgaccgatctggcgaaccacatgaagttccacaacgacgagaaaccgtacatttgttcggtctgcaacaaggtgtacctcaatctggacgagctgactgaacatatgaagaagacgcacaaccaggtcaaaccgtaccgatgccacatctgcgacaagacgtttacgcagtccaacaacctgaagacgcacatcaagacgcacatcttccaggatccgtacaagtgtcagatgtgttcccgttcgttccagcgagaggatgagtacggacagcacatgcttgtccacacggcggacaaaccgtacgagtgtacgtactgtggcaagcgtttcattcagtcgaacaatctgaaaacgcacgtccgaacgcacacgggcgagaaaccgtacagctgttcgatctgtctgcggaactttaaccagaagaacaacctgaacacgcacatgcgcatccacaccggtgagaaaccgttcgagtgtacaatctgcgacaagcgtttcaatcagtcgaacaacctgaacaaacacatcaagacgcacggtcaggagaaggaccagcagcaacagcagcagcaatcgcagcaccaacaccaccatcaccaccatcagcaacaccagcagcagcagcttccaagttga
Protein Sequence
MRLNIDDVYGPLKKRGSGVNVNLTFATATRTKRRRSRKIFSRTVLVRAGERIFIFGGFSAERSRFSVYCSSEGLDPLFDSIRVEVFGAEAARDVGIVQRRTGERGSVIQEDKRKVMLGKYGDASSSSMMNLESGLRNRVLYHQNMMGMNLMAEFYHHNPTLVNAATVSSSVTGSSSSSSNNSAIAQSQKMLNSLSGTIANAGGNHQQPSQHTNGTPLAISTVSTAATVTSTSSSSSSSSQQPLAQFQCQVCQKTYLTSAMLAVHMKTHDNAAGGFVSRQEATVGSSYLQPSSSSLEHVSAPAVAHGASSKTSPPLLLAQHSIKSEYAGTARGIGQFSSPYGIIKQFDCHICHKSFMTLMNLNLHMKIHENDQKVVAAATAAANVYSSHAGGTGTTYHHQLTHQQQLHPTLLQAASSSGAVPSATATTGRNADGVCQICHKTFNSTEQFTAHMKIHEEEFKNRALYHSSAATGSSTAVATSAAAQTINPFYPTLPQTLAPAASTQPQQQQQLPAVHLYESSKGHRCPICHKMSSNIIEHIKQHEGQLIMGGGGSSATAPGGGSPSVDRACATPGYQLNEETSQASSLAEVSDNEAGDDDQRKQHECLICHKKFSSSSNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYTCTICGKKFSQSNNLKTHIRTHTGERPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFAHPTDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQREDEYGQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYSCSICLRNFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQQQSQHQHHHHHHQQHQQQQLPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098693; iTF_00093149; iTF_00092939;
90% Identity
iTF_00093149;
80% Identity
iTF_00098693;