Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:129399-132614[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00018 0.011 15.5 1.9 1 21 53 73 53 74 0.95

2 17 0.12 7.2 6.6 0.3 2 19 107 123 106 125 0.83

3 17 8.1e-06 0.00048 19.7 6.2 1 23 532 554 532 554 0.98

4 17 2.9e-07 1.7e-05 24.2 0.5 1 23 560 582 560 582 0.99

5 17 2.3e-06 0.00014 21.4 0.2 1 23 588 610 588 610 0.98

6 17 2.8e-05 0.0016 18.0 0.6 2 23 616 637 615 637 0.96

7 17 2.7e-06 0.00016 21.2 5.0 1 23 643 665 643 665 0.99

8 17 0.00017 0.01 15.5 2.2 1 23 739 761 739 761 0.97

9 17 4.4e-06 0.00026 20.5 2.5 2 23 768 789 767 789 0.98

10 17 1.4e-06 8.2e-05 22.1 0.8 1 23 795 817 795 817 0.98

11 17 1.7e-06 0.0001 21.8 0.1 2 23 823 844 822 844 0.98

12 17 1.3e-06 7.6e-05 22.2 2.1 1 23 850 872 850 872 0.99

13 17 2.8e-06 0.00016 21.2 2.2 1 23 928 950 928 950 0.99

14 17 5.8e-07 3.4e-05 23.3 2.4 1 23 956 978 956 978 0.99

15 17 3.4e-05 0.002 17.7 0.3 1 23 984 1006 984 1006 0.98

16 17 2.4e-06 0.00014 21.3 0.3 2 23 1012 1033 1011 1033 0.98

17 17 3.9e-06 0.00023 20.7 1.0 1 23 1039 1061 1039 1061 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00018	0.011	15.5	1.9	1	21	53	73	53	74	0.95
2	17	0.12	7.2	6.6	0.3	2	19	107	123	106	125	0.83
3	17	8.1e-06	0.00048	19.7	6.2	1	23	532	554	532	554	0.98
4	17	2.9e-07	1.7e-05	24.2	0.5	1	23	560	582	560	582	0.99
5	17	2.3e-06	0.00014	21.4	0.2	1	23	588	610	588	610	0.98
6	17	2.8e-05	0.0016	18.0	0.6	2	23	616	637	615	637	0.96
7	17	2.7e-06	0.00016	21.2	5.0	1	23	643	665	643	665	0.99
8	17	0.00017	0.01	15.5	2.2	1	23	739	761	739	761	0.97
9	17	4.4e-06	0.00026	20.5	2.5	2	23	768	789	767	789	0.98
10	17	1.4e-06	8.2e-05	22.1	0.8	1	23	795	817	795	817	0.98
11	17	1.7e-06	0.0001	21.8	0.1	2	23	823	844	822	844	0.98
12	17	1.3e-06	7.6e-05	22.2	2.1	1	23	850	872	850	872	0.99
13	17	2.8e-06	0.00016	21.2	2.2	1	23	928	950	928	950	0.99
14	17	5.8e-07	3.4e-05	23.3	2.4	1	23	956	978	956	978	0.99
15	17	3.4e-05	0.002	17.7	0.3	1	23	984	1006	984	1006	0.98
16	17	2.4e-06	0.00014	21.3	0.3	2	23	1012	1033	1011	1033	0.98
17	17	3.9e-06	0.00023	20.7	1.0	1	23	1039	1061	1039	1061	0.98

Sequence Information

Coding Sequence: ATGATCCAAACTATGCAACTGCAGCAGCAGcaacaacaacaacaacaacaacaaGCAGCTCAAGTGCAGACACCGATCCAACAACAGCAATCGTGCAGATGCGAGTTCTGCGAGTATCTTCAGGCCAACCGTATCTCCCTCACAGGAGATCACTCCTTCCAGTGTGAGTTTTGTGGGGAAGGCTTTTCCAACCAAAACAGCTACAATCGGCATCGGTGCGGTAGCACCGACATCCAAGTGTACCGTTGTGAAAGCTGTCGCCATGAGTACGGTACCTCACGAACAATGCCCACGATCAACAGCGGCGAACCTCGTGACAAATGTGATATCTGCAATCGGAATTTCGATCATTCGATGCTAGACGATCATGTGAGCTGTGGGCCAGCGTTACCACCAGCATTGCCACCGCCGCCACCGACGCCCATCAGTAACTCATTAGCATCAATTGAAACAGTGCCAACGATGAGTATAGTAGCGGTGCCTCCTGTCCTGGGATCTGTTAACAGTAGTGGCGTCGGGAACGGCAGCAGCAACAACAACAACAACCTAGCCCCTAGCAAATCATATAATGTACCGATTCTCTTGGCATCGGTTTCCTCTACATCGCCCGCTGGAACATTTCGAGACACATCCAATGGTGGAACGAGCGATCTCAGTGCTGCAGCCAGTGTCCGCTCTATTGCCGATAGTCCGATGGAGCACGATATCGGTACGCTGGATCCGTTTGGATCGGACAGCGAGTGCATTAGTGAGTACCTTGGGCACGAATCCATGTCATCCGGCGCCTATGCCTCGACGTATTGCACCGGCAGAAAGATGGAATGCAGCTTGAGCGAATCTTCCGGTACAACGGGCTCTCTGCTACCGGAATCGGCCAAAACATACTTCGTGCTCGGCAATGTCGAGCTCCAGCAACCTGTTCAACCGACGGTCAATAACTCGGACATAGCGCAGACGTCAGTGACCCAGCACAATACCAACAGTATTAGCTCGAATGGTTACCACCATCGCCACATGCCACTGCAACAGCAGACAGCCCCTCCACCGCTTCACCATCATCAGCAACCCCCGCTGTCCATGCCTAATCTTCTGCATCATTTAACTCCCAAAGAGTACGAGGTCACAAGCCTCCAGCAGTACGATGATCAGCACTACGACGATGAGGATTACTCCACCATGTCCGAAGATGAAGCTATTGTTCCAACAGTAAATATGCTCGACCCGAGTGTGCGACAGTTTCTAATCGGTAGCTTTCCATTACAGGAACCTTATGCGAAATCACCTAATCAGGACCACGCCAAAACGGAACTGCCCATACAGGATACGATCGTGGATACGAGCACCAAGACGTTGCTACCTCCGGTCGTTACTCATCTGGGCAACGCAACGAACCAGTACACAATGCATGAGCTAAAACCGCCAATGGCCATAGACGCTCTAGGACCCATTGGACCTCTGTCACGCTGTGTCGATGAGGAGGAAGGAGGCAAATGTGACTCATCGTCCTCACTGAGGCCAACGGGAGGTATGGCACAAAAGCCCAGTGCCGAAGGGTTACAGGACGCGTCACGCGTTGGATCGACCGATCGTCCGCACAAGTGTCATATCTGTGAACGTTCGTACCGGAATCAAAAGAACCTCAAGTCACACCTCAAGGTCCACGAAGGCATTCGGGCGTATCAGTGTGAAATATGTGGCAAGAACTTTTCAGGGTCCAGCTACCTGGTCATTCACCGGAGGCGCCATACCGGCGAGCGACCCTTCAAGTGTTCCACCTGTGGTAAAGCGTTTGTTGATTCGCGGGCCCTCGCCGTCCACACGCGGCTACACAGTGGCGAACGGTTGAAGTGCGAAAAATGTGAGAAGACGTTCTCCAGTGTCAGTGCACTCACCGTCCACAACCGGCTACACACTGGCATTCATCCTTACAAATGCGAGCTGTGCAGCAAAACCTTCCCTCAGTACAACAATTTGAAGCATCACATGAAGAAGCATGATCAGCCGGGACCGGCCGAAAAGAAGTCTGGGCTGTGTACCGGCAACAGTAGCAACAGCTCGACCAGCACTACCAGCATCTCGCCGGTGTCCAGTAGTGCTCTAGAGGGACAGATGCACGATCCTGCTGCTGCACCCAGTGCTGCTGCCGCACACGTGCCCCTGCCACAGCCTACTCAAGCGATGGTACCCAGCTCGACCACTAGCAACATGTTCGAGTTCAAATGCCACATCTGTAGTAAGCTGTACAAATCATCCGCCGAGCTTCAGGACCATCTGAGTCAGCACAGCAAAGAGCGACCGAATCAGTGTGAATTCTGCTCGAAGGTATTCCCACGATCCTCGCATCTGATCATCCACCGGCGGCGTCACACCGGTGAGCGACCATTTAAGTGCAAATACTGTGACAAAGCGTTCGTCGATTCGCGGGCCCTCTCGGTACACACGCGACTCCACACCGGGGAGCGTGTAAAGTGCGAAATTTGTGAGAAAACATTCGCCAGTTCCAGCGGGTTGATCGTCCATCGGCGCATTCACACTGGCATCCATCCGTACAAGTGTGACTATTGTGAAAAATCGTTCGCACAATCGACCGCACTCAAGTATCACCTAAAAAAGCATGATACTTCCTCTTTGCCAACGACCACGACCTCCACCACCACCACGGCGACGACCACGGCTGCTGCTGGTGCTGCCGCGAGCACTGCAGCCATTGGAAGCTCATCCAATCAGCAGACGATACCGGTCAGCACCGGGGGTGGTGAAGCTACCGGTGGAAACGATCGTTACAAGTGTCTCACTtgtgggaaactgtttcgatcctcggaatatctggtgcgccatcggcgcacgcacagcggtgagcgtccgtatcagtgcgagatctgcggaaaacACTTTTCCACCATGAGCTATCTAGTCATCCACCGGCGTCGCCATACCTCGGAGCGGCCCTATAAATGCACCTCTTGCGAGAAAGCGTTCGTGGATTCGCGCGCTTTGCAGGAACACGCGCGGCTCCATACCGGGGATCGCGTCAAGTGTGAAATATGCCAAAAAACCTACTCCAGCGTCAGTAACTTGATCGTGCACCGGCGTATCCATAGCGGGATACATCCGTTCGAGTGTGGTAGCTGTGGTAAATCGTTCGCGCAGAAGAACGCCCTCAAGTATCACTTGAAAAAGCACAACAAACAAACGGAGACAGTCAATAATGAATAG
Protein Sequence: MIQTMQLQQQQQQQQQQQAAQVQTPIQQQQSCRCEFCEYLQANRISLTGDHSFQCEFCGEGFSNQNSYNRHRCGSTDIQVYRCESCRHEYGTSRTMPTINSGEPRDKCDICNRNFDHSMLDDHVSCGPALPPALPPPPPTPISNSLASIETVPTMSIVAVPPVLGSVNSSGVGNGSSNNNNNLAPSKSYNVPILLASVSSTSPAGTFRDTSNGGTSDLSAAASVRSIADSPMEHDIGTLDPFGSDSECISEYLGHESMSSGAYASTYCTGRKMECSLSESSGTTGSLLPESAKTYFVLGNVELQQPVQPTVNNSDIAQTSVTQHNTNSISSNGYHHRHMPLQQQTAPPPLHHHQQPPLSMPNLLHHLTPKEYEVTSLQQYDDQHYDDEDYSTMSEDEAIVPTVNMLDPSVRQFLIGSFPLQEPYAKSPNQDHAKTELPIQDTIVDTSTKTLLPPVVTHLGNATNQYTMHELKPPMAIDALGPIGPLSRCVDEEEGGKCDSSSSLRPTGGMAQKPSAEGLQDASRVGSTDRPHKCHICERSYRNQKNLKSHLKVHEGIRAYQCEICGKNFSGSSYLVIHRRRHTGERPFKCSTCGKAFVDSRALAVHTRLHSGERLKCEKCEKTFSSVSALTVHNRLHTGIHPYKCELCSKTFPQYNNLKHHMKKHDQPGPAEKKSGLCTGNSSNSSTSTTSISPVSSSALEGQMHDPAAAPSAAAAHVPLPQPTQAMVPSSTTSNMFEFKCHICSKLYKSSAELQDHLSQHSKERPNQCEFCSKVFPRSSHLIIHRRRHTGERPFKCKYCDKAFVDSRALSVHTRLHTGERVKCEICEKTFASSSGLIVHRRIHTGIHPYKCDYCEKSFAQSTALKYHLKKHDTSSLPTTTTSTTTTATTTAAAGAAASTAAIGSSSNQQTIPVSTGGGEATGGNDRYKCLTCGKLFRSSEYLVRHRRTHSGERPYQCEICGKHFSTMSYLVIHRRRHTSERPYKCTSCEKAFVDSRALQEHARLHTGDRVKCEICQKTYSSVSNLIVHRRIHSGIHPFECGSCGKSFAQKNALKYHLKKHNKQTETVNNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092937; iTF_00092286;
90% Identity: -
80% Identity: -